Christian Leborgne

Christian Leborgne

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Christian Leborgne

Christian Leborgne

Publications by authors named "Christian Leborgne"

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42Publications

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Peptides derived from the C-terminal domain of HIV-1 Viral Protein R in lipid bilayers: Structure, membrane positioning and gene delivery.

Biochim Biophys Acta Biomembr 2020 Feb 6;1862(2):183149. Epub 2019 Dec 6.

Laboratoire de Conception et Application de Molécules Bioactives UMR7199 CNRS - Université de Strasbourg, Faculté de Pharmacie, 67401 Illkirch, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.183149DOI Listing
February 2020

The absorption enhancer sodium deoxycholate promotes high gene transfer in skeletal muscles.

Int J Pharm 2017 May 14;523(1):291-299. Epub 2017 Mar 14.

Genethon, BP60, 91002 Evry cedex, France; Unité de Technologies Chimiques et Biologiques pour la Santé, CNRS UMR8258 - Inserm U1022 - Université Paris Descartes, Chimie ParisTech, 75006 Paris, France; Laboratoire de Conception et Application de Molécules Bioactives UMR7199 CNRS - Université de Strasbourg, LabEx Medalis, Faculté de Pharmacie, 67401 Illkirch, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.03.020DOI Listing
May 2017

Histidine-rich designer peptides of the LAH4 family promote cell delivery of a multitude of cargo.

J Pept Sci 2017 Apr 9;23(4):320-328. Epub 2017 Jan 9.

Université de Strasbourg, CNRS, UMR7177, Institut de Chimie, 4, Rue Blaise Pascal, 67070, Strasbourg, France.

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http://dx.doi.org/10.1002/psc.2955DOI Listing
April 2017

Low-Dose Liver-Targeted Gene Therapy for Pompe Disease Enhances Therapeutic Efficacy of ERT via Immune Tolerance Induction.

Mol Ther Methods Clin Dev 2017 Mar 11;4:126-136. Epub 2017 Jan 11.

Division of Medical Genetics, Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S23290501173000
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http://dx.doi.org/10.1016/j.omtm.2016.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363303PMC
March 2017

Enhanced efficacy from gene therapy in Pompe disease using coreceptor blockade.

Hum Gene Ther 2015 Jan;26(1):26-35

1 Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center , Durham, NC 27710.

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http://dx.doi.org/10.1089/hum.2014.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303018PMC
January 2015

Humoral and cellular capsid-specific immune responses to adeno-associated virus type 1 in randomized healthy donors.

J Immunol 2012 Jun 16;188(12):6418-24. Epub 2012 May 16.

Laboratoire d'Immunologie, Genethon, 91002 Evry Cedex, France.

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http://dx.doi.org/10.4049/jimmunol.1200620DOI Listing
June 2012

Smart DNA vectors based on cyclodextrin polymers: compaction and endosomal release.

Pharm Res 2012 Feb 17;29(2):384-96. Epub 2011 Aug 17.

Institut de Chimie et des Matériaux Paris Est, ICMPE Systèmes Polymères Complexes, UMR 7182, 2-8 rue Henri Dunant, 94320, Thiais, France.

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http://dx.doi.org/10.1007/s11095-011-0560-0DOI Listing
February 2012

Synthesis of poly(propylene glycol)-block-polyethylenimine triblock copolymers for the delivery of nucleic acids.

Macromol Biosci 2011 May 8;11(5):652-61. Epub 2011 Feb 8.

Institut Chimie et Matériaux de Paris Est, UMR 7182 Equipe Systèmes Polymères Complexes, Thiais, France.

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http://dx.doi.org/10.1002/mabi.201000404DOI Listing
May 2011

Investigation of DNA condensing properties of amphiphilic triblock cationic polymers by atomic force microscopy.

Langmuir 2010 Nov 7;26(22):17552-7. Epub 2010 Oct 7.

Laboratoire Structure et Activité des Biomolécules Normales et Pathologiques, Université d'Evry-Val-d'Essonne and INSERM U829, Evry, France.

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http://dx.doi.org/10.1021/la103066cDOI Listing
November 2010

Design and evaluation of histidine-rich amphipathic peptides for siRNA delivery.

Pharm Res 2010 Jul;27(7):1426-36

Genethon, 1bis rue de l'Internationale, BP60, 91002 Evry, France.

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http://dx.doi.org/10.1007/s11095-010-0138-2DOI Listing
July 2010

Nucleic acid transfer with hemifluorinated polycationic lipids.

Biomaterials 2010 Jun 29;31(17):4781-8. Epub 2010 Mar 29.

Laboratoire de Conception et Application de Molécules Bioactives, UMR 7199 CNRS-Université de Strasbourg, Faculté de Pharmacie, 67401 Illkirch Cedex, France.

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http://dx.doi.org/10.1016/j.biomaterials.2010.02.047DOI Listing
June 2010

"HFP" fluorinated cationic lipids for enhanced lipoplex stability and gene delivery.

Bioconjug Chem 2010 Feb;21(2):360-71

Laboratoire de Conception et Application de Molecules Bioactives, CNRS-Universite de Strasbourg, 74 route du Rhin, BP 60024, 67401 Illkirch Cedex, France.

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http://dx.doi.org/10.1021/bc900469zDOI Listing
February 2010

Development and characterization of new cyclodextrin polymer-based DNA delivery systems.

Bioconjug Chem 2008 Dec;19(12):2311-20

Institut de Chimie des Materiaux Paris Est, Systemes Polymeres Complexes, Universite Paris 12 Val de Marne, CNRS, 2-8 rue Henri Dunant, 94320 Thiais, France.

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http://dx.doi.org/10.1021/bc800070fDOI Listing
December 2008

Self-promoted cellular uptake of peptide/DNA transfection complexes.

Biochemistry 2007 Oct 12;46(40):11253-62. Epub 2007 Sep 12.

Université Louis Pasteur/CNRS, UMR 7177, Institut de Chimie de Strasbourg, 4, rue Blaise Pascal, 67070 Strasbourg, France.

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http://dx.doi.org/10.1021/bi700766jDOI Listing
October 2007

Amphiphilic poly[(propylene glycol)-block-(2-methyl-2-oxazoline)] copolymers for gene transfer in skeletal muscle.

ChemMedChem 2007 Aug;2(8):1202-7

Laboratoire Matériaux Polymères aux Interfaces-UMR CNRS 7581, Université d'Evry, 91025 Evry, France.

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http://doi.wiley.com/10.1002/cmdc.200700068
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http://dx.doi.org/10.1002/cmdc.200700068DOI Listing
August 2007

Optimising histidine rich peptides for efficient DNA delivery in the presence of serum.

J Control Release 2007 Mar 8;118(1):95-104. Epub 2006 Dec 8.

Faculté de chimie, Université Louis Pasteur/CNRS LC3-UMR7177, Institut le Bel, 4 rue Blaise Pascal, F-67070 Strasbourg, France.

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http://linkinghub.elsevier.com/retrieve/pii/S016836590600701
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http://dx.doi.org/10.1016/j.jconrel.2006.12.004DOI Listing
March 2007

Characterization of the gene transfer process mediated by histidine-rich peptides.

J Mol Med (Berl) 2007 Feb 17;85(2):191-201. Epub 2006 Nov 17.

Généthon-CNRS UMR 8115, 1bis rue de l'Internationale, BP60, 91002 Evry, France.

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http://link.springer.com/10.1007/s00109-006-0119-4
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http://dx.doi.org/10.1007/s00109-006-0119-4DOI Listing
February 2007

Dilution of reporter gene with stuffer DNA does not alter the transfection efficiency of polyethylenimines.

J Gene Med 2005 Nov;7(11):1459-67

Genethon-UMR 8115 CNRS, 1bis rue de l'Internationale, BP 60, F-91002 Evry, France.

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http://dx.doi.org/10.1002/jgm.805DOI Listing
November 2005

Cationic steroid antibiotics demonstrate DNA delivery properties.

J Control Release 2005 Sep;107(1):174-82

Genethon - UMR 8115 CNRS, 1bis rue de l'Internationale, BP 60, F-91002 Evry, France.

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http://dx.doi.org/10.1016/j.jconrel.2005.08.002DOI Listing
September 2005

Synthesis of linear polyethylenimine derivatives for DNA transfection.

Bioconjug Chem 2003 May-Jun;14(3):581-7

Laboratory Matériaux Polymères aux Interfaces, UMR CNRS 7581, University of Evry, Bld Mitterrand, 91025 Evry Cedex, France.

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https://pubs.acs.org/doi/10.1021/bc0200529
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http://dx.doi.org/10.1021/bc0200529DOI Listing
January 2004

Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells.

Proc Natl Acad Sci U S A 2003 Feb 31;100(4):1564-8. Epub 2003 Jan 31.

Généthon III-Centre National de la Recherche Scientifique Unité de Recherche Associée 1923, 1 Rue de l'Internationale, F-91002 Evry, France.

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http://dx.doi.org/10.1073/pnas.0337677100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149872PMC
February 2003

Intranasal gene delivery with a polyethylenimine-PEG conjugate.

J Control Release 2002 Jun;81(3):379-88

Généthon III-CNRS URA 1923, 1 Rue de l'Internationale, Evry, France.

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http://dx.doi.org/10.1016/s0168-3659(02)00080-9DOI Listing
June 2002