Publications by authors named "Christian Jäger"

45 Publications

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold-Hopping Approach.

ChemMedChem 2020 Dec 23. Epub 2020 Dec 23.

Department of Drug Design and Target Validation MWT, Fraunhofer Institute for Cell Therapy and Immunology IZI, Biocenter, Weinbergweg 22, 06120, Halle (Saale), Germany.

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December 2020

A Primary Evaluation of Potential Small-Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment.

ChemMedChem 2020 08 2;15(16):1499-1504. Epub 2020 Jul 2.

Department of Drug Design and Target Validation MWT, Fraunhofer Institute for Cell Therapy and Immunology IZI Biocenter, Weinbergweg 22, 06120, Halle (Saale), Germany.

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August 2020

A HF Loaded Lewis-Acidic Aluminium Chlorofluoride for Hydrofluorination Reactions.

Chemistry 2020 Jun 26;26(32):7314-7322. Epub 2020 May 26.

BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Straße, 12489, Berlin, Germany.

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June 2020

Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.

Cell Metab 2020 May 25;31(5):920-936.e7. Epub 2020 Mar 25.

Experimental & Molecular Immunology, Department of Infection and Immunity, Luxembourg Institute of Health, 29 Rue Henri Koch, Esch-sur-Alzette, Luxembourg; Odense Research Center for Anaphylaxis (ORCA), Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, Denmark; Immunology & Genetics, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 7 Avenue des Hauts Fourneaux, Esch-sur-Alzette, Luxembourg. Electronic address:

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May 2020

Metabolite profiling of the cold adaptation of Pseudomonas putida KT2440 and cold-sensitive mutants.

Environ Microbiol Rep 2019 12 10;11(6):777-783. Epub 2019 Oct 10.

Molecular Pathology of Cystic Fibrosis and Pseudomonas Genomics, Clinical Research Group, Hannover Medical School, 30625, Hannover, Germany.

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December 2019

Tertiary-Amine-Based Inhibitors of the Astacin Protease Meprin α.

ChemMedChem 2018 08 16;13(16):1619-1624. Epub 2018 Jul 16.

Department of Drug Design and Target Validation MWT, Fraunhofer Institute for Cell Therapy and Immunology IZI, Biocenter, Weinbergweg 22, 06120, Halle (Saale), Germany.

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August 2018

Quantification of Stable Isotope Traces Close to Natural Enrichment in Human Plasma Metabolites Using Gas Chromatography-Mass Spectrometry.

Metabolites 2018 Feb 14;8(1). Epub 2018 Feb 14.

Department of Bioinformatics and Biochemistry, BRICS, Technische Universität Braunschweig, 38106 Braunschweig, Germany.

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February 2018

Glutathione Primes T Cell Metabolism for Inflammation.

Immunity 2017 04;46(4):675-689

Department of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, Esch-sur-Alzette, L-4354, Luxembourg; Odense Research Center for Anaphylaxis, Department of Dermatology and Allergy Center, Odense University Hospital, University of Southern Denmark, Odense, DK-5000, Denmark. Electronic address:

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April 2017

Metabolic profiling of body fluids and multivariate data analysis.

MethodsX 2017 20;4:95-103. Epub 2017 Feb 20.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg; Braunschweig Integrated Centre of Systems Biology, University of Braunschweig, Rebenring 56, Braunschweig, Germany; Department of Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany.

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February 2017

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors.

Metab Eng 2017 09 12;43(Pt B):187-197. Epub 2016 Nov 12.

Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB Leuven, 3000 Leuven, Belgium; Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium. Electronic address:

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September 2017

Mechanochemically Induced Conversion of Crystalline Benzamide Polymorphs by Seeding.

Angew Chem Int Ed Engl 2016 11 20;55(46):14281-14285. Epub 2016 Oct 20.

BAM Federal Institute for Materials Research and Testing, Richard-Willstätter-Str. 11, 12489, Berlin, Germany.

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November 2016

Metabolic Profiling and Quantification of Neurotransmitters in Mouse Brain by Gas Chromatography-Mass Spectrometry.

Curr Protoc Mouse Biol 2016 Sep 1;6(3):333-342. Epub 2016 Sep 1.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.

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September 2016

Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions.

Cell Rep 2016 08 28;16(6):1536-1547. Epub 2016 Jul 28.

Department of Bioengineering, University of California, San Diego, La Jolla, CA 92037, USA; Moores Cancer Center, University of California, San Diego, La Jolla, CA 92037, USA. Electronic address:

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August 2016

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

Authors:
Uli Fechner Chris de Graaf Andrew E Torda Stefan Güssregen Andreas Evers Hans Matter Gerhard Hessler Nicola J Richmond Peter Schmidtke Marwin H S Segler Mark P Waller Stefanie Pleik Joan-Emma Shea Zachary Levine Ryan Mullen Karina van den Broek Matthias Epple Hubert Kuhn Andreas Truszkowski Achim Zielesny Johannes Hans Fraaije Ruben Serral Gracia Stefan M Kast Krishna C Bulusu Andreas Bender Abraham Yosipof Oren Nahum Hanoch Senderowitz Timo Krotzky Robert Schulz Gerhard Wolber Stefan Bietz Matthias Rarey Markus O Zimmermann Andreas Lange Manuel Ruff Johannes Heidrich Ionut Onlia Thomas E Exner Frank M Boeckler Marcel Bermudez Dzmitry S Firaha Oldamur Hollóczki Barbara Kirchner Christofer S Tautermann Andrea Volkamer Sameh Eid Samo Turk Friedrich Rippmann Simone Fulle Noureldin Saleh Giorgio Saladino Francesco L Gervasio Elke Haensele Lee Banting David C Whitley Jana Sopkova-de Oliveira Santos Ronan Bureau Timothy Clark Achim Sandmann Harald Lanig Patrick Kibies Jochen Heil Franziska Hoffgaard Roland Frach Julian Engel Steven Smith Debjit Basu Daniel Rauh Oliver Kohlbacher Frank M Boeckler Jonathan W Essex Michael S Bodnarchuk Gregory A Ross Arndt R Finkelmann Andreas H Göller Gisbert Schneider Tamara Husch Christoph Schütter Andrea Balducci Martin Korth Fidele Ntie-Kang Stefan Günther Wolfgang Sippl Luc Meva'a Mbaze Fidele Ntie-Kang Conrad V Simoben Lydia L Lifongo Fidele Ntie-Kang Philip Judson Jiří Barilla Miloš V Lokajíček Hana Pisaková Pavel Simr Natalia Kireeva Alexandre Petrov Denis Ostroumov Vitaly P Solovev Vladislav S Pervov Nils-Ole Friedrich Kai Sommer Matthias Rarey Johannes Kirchmair Eugen Proschak Julia Weber Daniel Moser Lena Kalinowski Janosch Achenbach Mark Mackey Tim Cheeseright Gerrit Renner Gerrit Renner Torsten C Schmidt Jürgen Schram Marion Egelkraut-Holtus Albert van Oeyen Tuomo Kalliokoski Denis Fourches Akachukwu Ibezim Chika J Mbah Umale M Adikwu Ngozi J Nwodo Alexander Steudle Brian B Masek Stephan Nagy David Baker Fred Soltanshahi Roman Dorfman Karen Dubrucq Hitesh Patel Oliver Koch Florian Mrugalla Stefan M Kast Qurrat U Ain Julian E Fuchs Robert M Owen Kiyoyuki Omoto Rubben Torella David C Pryde Robert Glen Andreas Bender Petr Hošek Vojtěch Spiwok Lewis H Mervin Ian Barrett Mike Firth David C Murray Lisa McWilliams Qing Cao Ola Engkvist Dawid Warszycki Marek Śmieja Andrzej J Bojarski Natalia Aniceto Alex Freitas Taravat Ghafourian Guido Herrmann Valentina Eigner-Pitto Alexandra Naß Rafał Kurczab Andrzej J Bojarski Andreas Lange Marcel B Günther Susanne Hennig Felix M Büttner Christoph Schall Adrian Sievers-Engler Francesco Ansideri Pierre Koch Thilo Stehle Stefan Laufer Frank M Böckler Barbara Zdrazil Floriane Montanari Gerhard F Ecker Christoph Grebner Anders Hogner Johan Ulander Karl Edman Victor Guallar Christian Tyrchan Johan Ulander Christian Tyrchan Wolfgang Klute Fredrik Bergström Christian Kramer Quoc Dat Nguyen Roland Frach Patrick Kibies Steven Strohfeldt Saraphina Böttcher Tim Pongratz Dominik Horinek Stefan M Kast Bernd Rupp Raed Al-Yamori Michael Lisurek Ronald Kühne Filipe Furtado Karina van den Broek Ludger Wessjohann Miriam Mathea Knut Baumann Siti Zuraidah Mohamad-Zobir Xianjun Fu Tai-Ping Fan Andreas Bender Maximilian A Kuhn Christoph A Sotriffer Azedine Zoufir Xitong Li Lewis Mervin Ellen Berg Mark Polokoff Wolf D Ihlenfeldt Wolf D Ihlenfeldt Jette Pretzel Zayan Alhalabi Robert Fraczkiewicz Marvin Waldman Robert D Clark Neem Shaikh Prabha Garg Alexander Kos Hans-Jürgen Himmler Achim Sandmann Christophe Jardin Heinrich Sticht Thomas B Steinbrecher Markus Dahlgren Daniel Cappel Teng Lin Lingle Wang Goran Krilov Robert Abel Richard Friesner Woody Sherman Ina A Pöhner Joanna Panecka Rebecca C Wade Stefan Bietz Karen T Schomburg Matthias Hilbig Matthias Rarey Christian Jäger Vivien Wieczorek Lance M Westerhoff Oleg Y Borbulevych Hans-Ulrich Demuth Mirko Buchholz Denis Schmidt Thomas Rickmeyer Timo Krotzky Peter Kolb Sumit Mittal Elsa Sánchez-García Mauro S Nogueira Tiago B Oliveira Fernando B da Costa Thomas J Schmidt

J Cheminform 2016 Apr 26;8(Suppl 1):18. Epub 2016 Apr 26.

Central Institute for Scientific Computing (ZISC), FAU-Erlangen-Nürnberg, Martensstr. 5a, 91058, Erlangen, Germany.

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April 2016

Isotopologue ratio normalization for non-targeted metabolomics.

J Chromatogr A 2015 Apr 17;1389:112-9. Epub 2015 Feb 17.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 7, Avenue des Hauts-Fourneaux, L-4362 Esch-Belval, Luxembourg. Electronic address:

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April 2015

Carbon dioxide adsorption in betulin-based micro- and macroporous polyurethanes.

ChemistryOpen 2013 Feb 18;2(1):17-20. Epub 2013 Jan 18.

Department of Colloid Chemistry, Max Planck Institute of Colloids and Interfaces, Science Park Golm 14424 Potsdam (Germany) E-mail:

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February 2013

Fragment formula calculator (FFC): determination of chemical formulas for fragment ions in mass spectrometric data.

Anal Chem 2014 Feb 5;86(4):2221-8. Epub 2014 Feb 5.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg , 7, avenue des Hauts-Fourneaux, L-4362 Esch-Belval, Luxembourg.

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February 2014

Chemical and morphological changes in hydrochars derived from microcrystalline cellulose and investigated by chromatographic, spectroscopic and adsorption techniques.

Bioresour Technol 2013 Dec 8;150:98-105. Epub 2013 Oct 8.

Leibniz Institute for Agricultural Engineering Potsdam-Bornim e.V., Max-Eyth-Allee 100, 14469 Potsdam, Germany. Electronic address:

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December 2013

Gate effects in a hexagonal zinc-imidazolate-4-amide-5-imidate framework with flexible methoxy substituents and CO2 selectivity.

Chem Commun (Camb) 2013 Sep 22;49(69):7599-601. Epub 2013 Jul 22.

Institut für Chemie, Anorganische Chemie, Universität Potsdam, Karl-Liebknecht-Strasse 24-25, 14476 Potsdam, Germany.

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September 2013