Publications Authored by Christian Grommes

Pretreatment dynamic contrast-enhanced MRI biomarkers correlate with progression-free survival in primary central nervous system lymphoma.

Authors:

Vaios Hatzoglou Jung Hun Oh Olivia Buck Xuling Lin Michelle Lee Amita Shukla-Dave Robert J Young Kyung K Peck Behroze Vachha Andrei I Holodny Christian Grommes

J Neurooncol 2018 Aug 2. Epub 2018 Aug 2.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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August 2018

Treatment of Primary Central Nervous System Lymphoma: From Chemotherapy to Small Molecules.

Authors:

Joe S Mendez Christian Grommes

Am Soc Clin Oncol Educ Book 2018 May(38):604-615

From the Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Neurology, Weill Cornell Medical College, New York, NY.

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May 2018

The elderly left behind-changes in survival trends of primary central nervous system lymphoma over the past 4 decades.

Authors:

Joe S Mendez Quinn T Ostrom Haley Gittleman Carol Kruchko Lisa M DeAngelis Jill S Barnholtz-Sloan Christian Grommes

Neuro Oncol 2018 Apr;20(5):687-694

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York.

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April 2018

Updates on Primary Central Nervous System Lymphoma.

Authors:

Lauren R Schaff Christian Grommes

Curr Oncol Rep 2018 Feb 28;20(2):11. Epub 2018 Feb 28.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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February 2018

EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer.

Authors:

Barbara Oldrini Wan-Ying Hsieh Hediye Erdjument-Bromage Paolo Codega Maria Stella Carro Alvaro Curiel-García Carl Campos Maryam Pourmaleki Christian Grommes Igor Vivanco Daniel Rohle Craig M Bielski Barry S Taylor Travis J Hollmann Marc Rosenblum Paul Tempst John Blenis Massimo Squatrito Ingo K Mellinghoff

Nat Commun 2017 12 11;8(1):2035. Epub 2017 Dec 11.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.

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December 2017

Retrospective review of safety and efficacy of programmed cell death-1 inhibitors in refractory high grade gliomas.

Authors:

Samantha N Reiss Prakirthi Yerram Lisa Modelevsky Christian Grommes

J Immunother Cancer 2017 12 19;5(1):99. Epub 2017 Dec 19.

Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA.

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December 2017

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma.

Cancer Discov 2017 09 15;7(9):1018-1029. Epub 2017 Jun 15.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York.

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September 2017

Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma.

Neurol Genet 2017 Aug 11;3(4):e164. Epub 2017 Jul 11.

New York Genome Center (K.O.W., M.O.F., N.R., A.-K.E., B.-J.C., K.A., M.S., V.V., E.A.B., J.L.M.V., M.C.Z., V.J., R.B.D.); IBM Thomas J. Watson Research Center (T.K., K.R., F.U., R.N., E.B., L.P., A.K.R.); Columbia University Medical Center (J.N.B., A.B.L., P.C., V.J.); Memorial Sloan-Kettering Cancer Center (C.G.), New York, NY; IBM Watson Health (S.H., V.V.M.), Boca Raton, FL; Laboratory of Molecular Neuro-Oncology (M.O.F., R.B.D.), and Howard Hughes Medical Institute (R.B.D.), The Rockefeller University, New York, NY. B.-J.C. is currently affiliated with Google, New York, NY. V.V. is currently affiliated with 23andMe, Inc., Mountain View, CA. E.A.B. is currently affiliated with Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.

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August 2017

Primary CNS Lymphoma.

Authors:

Christian Grommes Lisa M DeAngelis

J Clin Oncol 2017 Jul 22;35(21):2410-2418. Epub 2017 Jun 22.

All authors: Memorial Sloan Kettering Cancer Center, New York, NY.

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July 2017

Ibrutinib in PCNSL: The Curious Cases of Clinical Responses and Aspergillosis.

Authors:

Christian Grommes Anas Younes

Cancer Cell 2017 06 25;31(6):731-733. Epub 2017 May 25.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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June 2017

Molecular and Clinical Effects of Notch Inhibition in Glioma Patients: A Phase 0/I Trial.

Clin Cancer Res 2016 Oct 6;22(19):4786-4796. Epub 2016 May 6.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York.

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October 2016

Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid.

J Clin Oncol 2016 Jul 9;34(20):2404-15. Epub 2016 May 9.

Elena I. Pentsova, Ronak H. Shah, Jiabin Tang, Adrienne Boire, Daoqi You, Samuel Briggs, Antonio Omuro, Xuling Lin, Martin Fleisher, Christian Grommes, Katherine S. Panageas, Fanli Meng, S. Duygu Selcuklu, Shahiba Ogilvie, Natalie Distefano, Larisa Shagabayeva, Marc Rosenblum, Lisa M. DeAngelis, Agnes Viale, Ingo K. Mellinghoff, and Michael F. Berger, Memorial Sloan Kettering Cancer Center; Ingo K. Mellinghoff, Weill-Cornell Graduate School of Biomedical Sciences; and Michael F. Berger, Weill-Cornell Medical College, New York, NY.

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July 2016

Posterior Reversible Encephalopathy Syndrome in Patients With Cancer.

Authors:

Samuel Singer Christian Grommes Anne S Reiner Marc K Rosenblum Lisa M DeAngelis

Oncologist 2015 Jul 1;20(7):806-11. Epub 2015 Jun 1.

Departments of Neurology, Epidemiology and Biostatistics, and Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA

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July 2015

R-MPV followed by high-dose chemotherapy with TBC and autologous stem-cell transplant for newly diagnosed primary CNS lymphoma.

Authors:

Antonio Omuro Denise D Correa Lisa M DeAngelis Craig H Moskowitz Matthew J Matasar Thomas J Kaley Igor T Gavrilovic Craig Nolan Elena Pentsova Christian C Grommes Katherine S Panageas Raymond E Baser Geraldine Faivre Lauren E Abrey Craig S Sauter

Blood 2015 Feb 7;125(9):1403-10. Epub 2015 Jan 7.

Department of Medicine, and.

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February 2015

Phase II study of bevacizumab, temozolomide, and hypofractionated stereotactic radiotherapy for newly diagnosed glioblastoma.

Clin Cancer Res 2014 Oct 8;20(19):5023-31. Epub 2014 Aug 8.

Department of Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York. Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York.

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October 2014

Bevacizumab for the treatment of high-grade glioma: an update after phase III trials.

Authors:

Mustafa Khasraw Malaka Ameratunga Christian Grommes

Expert Opin Biol Ther 2014 May 22;14(5):729-40. Epub 2014 Mar 22.

Geelong Hospital, Andrew Love Cancer Centre , 70 Swanston Street, Geelong, VIC 3220 , Australia +61 3 42152700 ; +61 3 42152836 ;

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May 2014

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

Science 2013 May 4;340(6132):626-30. Epub 2013 Apr 4.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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May 2013

Retrospective analysis of the effects of steroid therapy and antidiabetic medication on survival in diabetic glioblastoma patients.

Authors:

Mary R Welch Christian Grommes

CNS Oncol 2013 May;2(3):237-46

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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May 2013

The PPARγ agonist pioglitazone crosses the blood-brain barrier and reduces tumor growth in a human xenograft model.

Authors:

Christian Grommes J Colleen Karlo Andrew Caprariello D'Arbra Blankenship Anne Dechant Gary E Landreth

Cancer Chemother Pharmacol 2013 Apr 29;71(4):929-36. Epub 2013 Jan 29.

Department of Neuroscience, Case Western Reserve University, Cleveland, OH, USA.

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April 2013

Bevacizumab for the treatment of high-grade glioma.

Authors:

Mustafa Khasraw Marcelle Simeonovic Christian Grommes

Expert Opin Biol Ther 2012 Aug 5;12(8):1101-11. Epub 2012 Jun 5.

Daekin University, Geelong Hospital, Andrew Love Cancer Centre, School of Medicine, 70 Swanston Street, Geelong VIC 3220, Australia.

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August 2012

Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors.

Cancer Discov 2012 May 31;2(5):458-71. Epub 2012 Mar 31.

Human Oncology and Pathogenesis Program, Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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May 2012

"Pulsatile" high-dose weekly erlotinib for CNS metastases from EGFR mutant non-small cell lung cancer.

Authors:

Christian Grommes Geoffrey R Oxnard Mark G Kris Vincent A Miller William Pao Andrei I Holodny Jennifer L Clarke Andrew B Lassman

Neuro Oncol 2011 Dec 24;13(12):1364-9. Epub 2011 Aug 24.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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December 2011

Treatment of epidural spinal cord involvement from germ cell tumors with chemotherapy.

Authors:

Christian Grommes George J Bosl Lisa M DeAngelis

Cancer 2011 May 29;117(9):1911-6. Epub 2010 Nov 29.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York 100685, USA.

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May 2011

Kitten-transmitted Bordetella bronchiseptica infection in a patient receiving temozolomide for glioblastoma.

Authors:

Gil Redelman-Sidi Christian Grommes Genovefa Papanicolaou

J Neurooncol 2011 Apr 30;102(2):335-9. Epub 2010 Jul 30.

Department of Medicine, Infectious Disease, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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April 2011

The stepping test: a step back in history.

Authors:

Christian Grommes Devon Conway

J Hist Neurosci 2011 Jan;20(1):29-33

Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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January 2011

Inverse association of PPARγ agonists use and high grade glioma development.

Authors:

Christian Grommes Devon S Conway Amer Alshekhlee Jill S Barnholtz-Sloan

J Neurooncol 2010 Nov 5;100(2):233-9. Epub 2010 May 5.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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November 2010

Corpus callosum dysgenesis limits MRI changes to one hemisphere in status epilepticus.

Authors:

Christian Grommes Roger Oghlakian Kristina A Blackham Michael A De Georgia

Neurology 2009 Mar;72(10):942

Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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March 2009

Cardiac papillary fibroelastoma mimicking left atrial appendage thrombus.

Authors:

Julio Barcena Jon C George Christian Grommes Arie Blitz Robert Gilkeson Brian D Hoit

J Am Soc Echocardiogr 2008 Oct 14;21(10):1177.e1-2. Epub 2008 Jan 14.

Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106-5038, USA.

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October 2008

Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases.

Authors:

Christian Grommes C Y Daniel Lee Brandy L Wilkinson Qingguang Jiang Jessica L Koenigsknecht-Talboo Brian Varnum Gary E Landreth

J Neuroimmune Pharmacol 2008 Jun 10;3(2):130-40. Epub 2007 Oct 10.

Alzheimer Research Laboratory, Department of Neurosciences, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH 44106, USA.

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June 2008

Lambert-Eaton syndrome with large-cell neuroendocrine carcinoma of the lung.

Authors:

Christian Grommes David C Preston Zaid Al-Kadhimi Amer Alshekhlee

Muscle Nerve 2008 Jun;37(6):786-9

The Neurological Institutes, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106-5040, USA.

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June 2008

Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment.

Authors:

Christian Grommes Gary E Landreth Magdalena Sastre Martina Beck Douglas L Feinstein Andreas H Jacobs Uwe Schlegel Michael T Heneka

Mol Pharmacol 2006 Nov 3;70(5):1524-33. Epub 2006 Aug 3.

Department of Neurosciences, Alzheimer Research Laboratory, Case Western Reserve University, Cleveland, Ohio, USA.

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November 2006

Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia.

Authors:

Brandy Wilkinson Jessica Koenigsknecht-Talboo Christian Grommes C Y Daniel Lee Gary Landreth

J Biol Chem 2006 Jul 25;281(30):20842-50. Epub 2006 May 25.

Alzheimer Research Laboratory, Department of Neuroscience, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.

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July 2006

The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells.

Authors:

Christian Grommes Gary E Landreth Uwe Schlegel Michael T Heneka

J Pharmacol Exp Ther 2005 May 21;313(2):806-13. Epub 2005 Jan 21.

Department of Neurosciences, Alzheimer Research Laboratory, Case Western Reserve University, Cleveland, Ohio, USA.

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May 2005

Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists.

Authors:

Christian Grommes Gary E Landreth Michael T Heneka

Lancet Oncol 2004 Jul;5(7):419-29

Department of Neurosciences, Alzheimer Research Laboratory, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

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July 2004

Different mechanisms of secondary neuronal damage in thalamic nuclei after focal cerebral ischemia in rats.

Authors:

Marcel Dihné Christian Grommes Michael Lutzenburg Otto W Witte Frank Block

Stroke 2002 Dec;33(12):3006-11

Department of Neurology, Rheinisch Westfälische Technische Hochschule-Aachen, Aachen, Germany.

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December 2002

Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma.

Authors:

Thomas Zander Jürgen A Kraus Christian Grommes Uwe Schlegel Douglas Feinstein Thomas Klockgether Gary Landreth Jessica Koenigsknecht Michael T Heneka

J Neurochem 2002 Jun;81(5):1052-60

Department of Neurology, University Bonn, Germany.

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June 2002

Christian Grommes

Christian Grommes

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