Publications by authors named "Christian Grohe"

96Publications

Optimizing therapy sequence to prevent patient attrition in EGFR mutation-positive advanced or metastatic NSCLC.

Future Oncol 2020 Oct 23. Epub 2020 Oct 23.

Department of Hematology & Oncology, University Department Internal Medicine-Oncology, Pius-Hospital, Medical Campus University of Oldenburg, Oldenburg, Germany.

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http://dx.doi.org/10.2217/fon-2020-0854DOI Listing
October 2020

Osimertinib in Resected -Mutated Non-Small-Cell Lung Cancer.

N Engl J Med 2020 10 19;383(18):1711-1723. Epub 2020 Sep 19.

From the Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, and Guangdong Academy of Medical Sciences, Guangzhou (Y.-L.W.), the Thoracic Surgery Department, National Cancer Center-National Clinical Research Center for Cancer-Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.H.), and the Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai (S.L.) - all in China; the Department of Thoracic Surgery and Oncology, National Cancer Center Hospital East, Kashiwa (M.T.), and the Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama (T.K.) - both in Japan; the Department of Medical Oncology, Austin Health, Melbourne, VIC, Australia (T.J.); the Department of Respiratory Diseases, Evangelische Lungenklinik, Berlin (C.G.); the Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona (M.M.), and the Department of Oncology, Hospital Universitario Fundación Jiménez Díaz, Madrid (M.D.); the David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles (J.W.G.); the Center of Innovative Technologies and Oncology, N.N. Blokhin Russian Cancer Center, Russian Academy of Medical Sciences, Moscow (K.L.); the Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine (S.-W.K.), and the Precision Medicine Lung Cancer Center, Konkuk University Medical Center (K.-Y.L.) - both in Seoul, South Korea; the Department of Thoracic Surgery, Cho Ray Hospital, Ho Chi Minh City, Vietnam (H.-V.V.); the Division of Medical Oncology, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand (C.A.); the Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (C.-J.Y.); the Division of Thoracic Oncology, European Institute of Oncology, IRCCS, Milan (F.M.), and Medical Oncology 2, Istituto Oncologico Veneto, IRCCS, Padua (L.B.) - both in Italy; the Department of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre and the University of Toronto, Toronto (F.A.S.); Late Oncology Statistics, AstraZeneca, Gaithersburg, MD (L.Z.); Late Oncology Statistics (R.H.) and Oncology Research and Development (A.A., Y.R.), AstraZeneca, Cambridge, United Kingdom; and Section of Medical Oncology, Yale School of Medicine and Yale Cancer Center, New Haven, CT (R.S.H.).

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http://dx.doi.org/10.1056/NEJMoa2027071DOI Listing
October 2020

Pemetrexed-Based Chemotherapy Is Inferior to Pemetrexed-Free Regimens in Thyroid Transcription Factor 1 (TTF-1)-Negative, EGFR/ALK-Negative Lung Adenocarcinoma: A Propensity Score Matched Pairs Analysis.

Clin Lung Cancer 2020 May 22. Epub 2020 May 22.

Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Division of Pulmonary Inflammation, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1016/j.cllc.2020.05.014DOI Listing
May 2020

Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry.

J Clin Med 2020 05 13;9(5). Epub 2020 May 13.

Universitätsklinik Köln- Herzzentrum, Klinik III für Innere Medizin, 50937 Köln, Germany.

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http://dx.doi.org/10.3390/jcm9051456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290703PMC
May 2020

Anti-angiogenic agents in the age of resistance to immune checkpoint inhibitors: Do they have a role in non-oncogene-addicted non-small cell lung cancer?

Lung Cancer 2020 06 20;144:76-84. Epub 2020 Apr 20.

Boehringer Ingelheim International GmbH, Binger Strasse 173, 55216 Ingelheim am Rhein, Germany; Institute of Pharmacology, Johannes Gutenberg-University Mainz, 55122 Mainz, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2020.04.009DOI Listing
June 2020

Antwort.

Dtsch Med Wochenschr 2020 Apr 15;145(8):573. Epub 2020 Apr 15.

Klinik für Pneumologie, Evangelische Lungenklinik Berlin.

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http://dx.doi.org/10.1055/a-1110-6220DOI Listing
April 2020

[Pneumonia].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2020 03 19;145(6):345. Epub 2020 Mar 19.

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http://dx.doi.org/10.1055/a-0952-9509DOI Listing
March 2020

Hyponatremia in Oncology Patients.

Authors:
Christian Grohé

Front Horm Res 2019 15;52:161-166. Epub 2019 Jan 15.

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http://dx.doi.org/10.1159/000493245DOI Listing
June 2020

Prevalence of sarcoidosis-associated pulmonary hypertension: cumulative analysis of two PULSAR studies.

Eur Respir J 2020 02 12;55(2). Epub 2020 Feb 12.

Dept of Internal Medicine II - Pneumology/Cardiology, University Hospital Bonn, Bonn, Germany

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http://dx.doi.org/10.1183/13993003.02223-2019DOI Listing
February 2020

[Medical expert opinion of occupational illness using the example of pneumological diseases].

Dtsch Med Wochenschr 2019 10 21;144(21):1496-1503. Epub 2019 Oct 21.

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http://dx.doi.org/10.1055/a-0754-0528DOI Listing
October 2019

[Occupational Diseases].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2019 10 21;144(21):1469. Epub 2019 Oct 21.

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http://dx.doi.org/10.1055/a-0718-6693DOI Listing
October 2019

Use of Anticholinergic and Antifungal Pharmacotherapy for the Management of Bronchorrhea in a Patient With BRAF-Mutated Adenocarcinoma of the Lung.

J Pain Symptom Manage 2020 01 11;59(1):e14-e16. Epub 2019 Oct 11.

Department of Respiratory Medicine, ELK Thorax Center (Evangelische Lungenklinik Berlin), Berlin, Germany.

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http://dx.doi.org/10.1016/j.jpainsymman.2019.10.001DOI Listing
January 2020

Defining aggressive or early progressing nononcogene-addicted non-small-cell lung cancer: a separate disease entity?

Future Oncol 2019 Apr 13;15(12):1363-1383. Epub 2019 Feb 13.

Boehringer Ingelheim Pharma GmbH & Co, KG, Germany & Institute of Pharmacology, Johannes Gutenberg-University Mainz, Germany.

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http://dx.doi.org/10.2217/fon-2018-0948DOI Listing
April 2019

[COPD - a Common Clinical Condition].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2019 01 2;144(1). Epub 2019 Jan 2.

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http://dx.doi.org/10.1055/a-0677-3294DOI Listing
January 2019

Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease.

Med Mycol Case Rep 2018 Jun 6;20:28-32. Epub 2018 Feb 6.

Department of Respiratory Medicine, Evangelische Lungenklinik Berlin, Lindenberger Weg 27, 13125 Berlin, Germany.

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http://dx.doi.org/10.1016/j.mmcr.2018.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105918PMC
June 2018

Large cell neuroendocrine lung carcinoma induces peripheral T-cell repertoire alterations with predictive and prognostic significance.

Lung Cancer 2018 05 6;119:48-55. Epub 2018 Mar 6.

Translational Research Unit, Thoraxklinik at Heidelberg University Hospital, Germany; Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Member of the German Center for Lung Research (DZL), Germany.

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http://dx.doi.org/10.1016/j.lungcan.2018.03.002DOI Listing
May 2018

Cardiovascular magnetic resonance imaging and clinical performance of somatostatin receptor positron emission tomography in cardiac sarcoidosis.

ESC Heart Fail 2018 04 12;5(2):249-261. Epub 2017 Dec 12.

Department of Internal Medicine II, Cardiology, Pneumology and Angiology, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1002/ehf2.12243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880659PMC
April 2018

[Concepts to Optimize Home Care of Patients with Mechanical Ventilation].

Dtsch Med Wochenschr 2017 Aug 15;142(16):1205-1210. Epub 2017 Aug 15.

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http://dx.doi.org/10.1055/s-0042-121789DOI Listing
August 2017

[Extraclinical Ventilation: An Increasing Challenge].

Dtsch Med Wochenschr 2017 Aug 15;142(16):1181. Epub 2017 Aug 15.

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http://dx.doi.org/10.1055/s-0042-109200DOI Listing
August 2017

[Current Therapeutic Approaches to Sarcoidosis].

Dtsch Med Wochenschr 2017 Jan 5;142(1):17-23. Epub 2017 Jan 5.

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http://dx.doi.org/10.1055/s-0042-109195DOI Listing
January 2017

[Granulomatous systemic diseases - a differential diagnostic challenge].

Dtsch Med Wochenschr 2017 Jan 5;142(1). Epub 2017 Jan 5.

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http://dx.doi.org/10.1055/s-0042-108659DOI Listing
January 2017

ctDNA Determination of EGFR Mutation Status in European and Japanese Patients with Advanced NSCLC: The ASSESS Study.

J Thorac Oncol 2016 Oct 25;11(10):1682-9. Epub 2016 Jul 25.

Cell Biology and Biotherapy Unit, National Cancer Institute "Pascale Foundation," Institute of Hospitalization and Scientific Care (IRCCS), Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.05.036DOI Listing
October 2016

[Obstructive lung disease: chronic progression must be stopped].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2016 05 13;141(10):686. Epub 2016 May 13.

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http://dx.doi.org/10.1055/s-0042-106912DOI Listing
May 2016

[Not Available].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2016 Apr 14;141(8):529. Epub 2016 Apr 14.

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http://dx.doi.org/10.1055/s-0042-100795DOI Listing
April 2016

Hyponatremia in cancer patients: Time for a new approach.

Crit Rev Oncol Hematol 2016 Jun 10;102:15-25. Epub 2016 Mar 10.

Medical Oncology, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria Ospedali Riuniti Umberto I, GM Lancisi, G Salesi, Ancona, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S10408428163005
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http://dx.doi.org/10.1016/j.critrevonc.2016.03.010DOI Listing
June 2016

SIADH: differential diagnosis and clinical management.

Endocrine 2017 Jan 30;55(1):311-319. Epub 2016 Mar 30.

Department of Endocrinology, Metabolism and Nutrition, Instituto de Investigación Sanitaria San Carlos (IdISSC) Hospital Clínico San Carlos, Madrid, Spain.

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http://dx.doi.org/10.1007/s12020-016-0936-3DOI Listing
January 2017

Cardiovascular magnetic resonance-guided diagnosis of cardiac affection in a Caucasian sarcoidosis population.

Sarcoidosis Vasc Diffuse Lung Dis 2016 Jan 18;32(4):325-35. Epub 2016 Jan 18.

University Hospital Bonn, Department of Internal Medicine II, Cardiology, Pneumology and Angiology, Bonn, Germany.

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January 2016

[Advantages of Ticagrelor outweigh also in COPD patients].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2016 Jan 22;141(2):78. Epub 2016 Jan 22.

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http://dx.doi.org/10.1055/s-0041-107741DOI Listing
January 2016

Hyponatraemia--SIADH in lung cancer diagnostic and treatment algorithms.

Crit Rev Oncol Hematol 2015 Oct 23;96(1):1-8. Epub 2015 Apr 23.

Department 2 of Internal Medicine, Nephrology, University Hospital, Cologne, Germany.

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http://dx.doi.org/10.1016/j.critrevonc.2015.04.005DOI Listing
October 2015

[Lung cancer therapy in transition: targeted therapies are coming].

Authors:
Christian Grohé

Dtsch Med Wochenschr 2015 Mar 3;140(5):316. Epub 2015 Mar 3.

Evangelische Lungenklinik Berlin.

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http://dx.doi.org/10.1055/s-0041-100764DOI Listing
March 2015

Experience with afatinib in patients with non-small cell lung cancer progressing after clinical benefit from gefitinib and erlotinib.

Oncologist 2014 Oct 17;19(10):1100-9. Epub 2014 Sep 17.

Department of Medical Oncology, West German Cancer Center, University Hospital Essen, Essen, Germany; Division of Thoracic Oncology, Ruhrlandklinik, West German Lung Center, University Duisburg-Essen, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany, Department of Medical Oncology, Klinik Löwenstein, Löwenstein, Germany; Department of Respiratory Medicine, Evangelische· Lungenklinik, Berlin, Germany; Department of Pneumology, Evangelisches Diakonissenkrankenhaus, Leipzig, Germany; Translational Lung Research Center Heidelberg, Heidelberg, Germany; Department of Pneumology and Thoracic Oncology, Klinik Schillerhoehe, Gerlingen, Germany; Department of Hematology and Medical Oncology, Zentralklinik, Bad Berka, Germany; Haemato-Oncology Hamburg, Hamburg, Germany; Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim, Germany.

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http://dx.doi.org/10.1634/theoncologist.2014-0103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200993PMC
October 2014

A rapid and efficient way to manage hyponatremia in patients with SIADH and small cell lung cancer: treatment with tolvaptan.

BMC Pulm Med 2013 Aug 29;13:55. Epub 2013 Aug 29.

ELK Department of Respiratory Diseases, Lindenberger Weg 27, 13125, Berlin, Germany.

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http://dx.doi.org/10.1186/1471-2466-13-55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851291PMC
August 2013

VEGF gene haplotypes are associated with sarcoidosis.

Chest 2010 Jan 9;137(1):156-63. Epub 2009 Sep 9.

Department of Internal Medicine II, Division of Pneumology, University of Bonn, Sigmund-Freud-Str. 25, D-53105 Bonn, Germany.

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http://dx.doi.org/10.1378/chest.09-1003DOI Listing
January 2010

Lack of gelsolin promotes perpetuation of atrial fibrillation in the mouse heart.

J Interv Card Electrophysiol 2009 Oct 8;26(1):3-10. Epub 2009 Aug 8.

Department of Medicine-Cardiology, University of Bonn, Sigmund Freud Strasse 25, 53105, Bonn, Germany.

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http://dx.doi.org/10.1007/s10840-009-9425-4DOI Listing
October 2009

Toll-like receptor 2 gene polymorphisms Arg677Trp and Arg753Gln in chronic obstructive pulmonary disease.

Lung 2009 May-Jun;187(3):173-8. Epub 2009 Apr 19.

Department of Pneumology, Medical Clinic II, University of Bonn, Sigmund-Freud-Strasse 25, Bonn, Germany.

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http://dx.doi.org/10.1007/s00408-009-9144-8DOI Listing
July 2009

Polymorphisms of the beta2 adrenoreceptor gene in chronic obstructive pulmonary disease.

Ther Adv Respir Dis 2009 Feb;3(1):3-10

St. Georg Medical Center, Robert-Koch-Hospital, Leipzig, Germany.

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http://dx.doi.org/10.1177/1753465809102553DOI Listing
February 2009

Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of toll-like receptor 9.

Cardiovasc Res 2008 Apr 14;78(1):26-35. Epub 2008 Jan 14.

Department for Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Sigmund-Freud-Strasse 25, Bonn 53105, Germany.

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http://dx.doi.org/10.1093/cvr/cvn011DOI Listing
April 2008

CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo.

Respir Res 2007 Oct 9;8:72. Epub 2007 Oct 9.

Department for Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Sigmund-Freud-Strasse 25, 53125 Bonn, Germany.

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http://dx.doi.org/10.1186/1465-9921-8-72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173891PMC
October 2007

Hodgkin's lymphoma in a patient with Jo-1 syndrome.

Virchows Arch 2007 Jul 24;451(1):101-4. Epub 2007 May 24.

Department of Pathology, University of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany.

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http://dx.doi.org/10.1007/s00428-007-0429-0DOI Listing
July 2007

Toll-like receptor 4 modulates myocardial ischaemia-reperfusion injury: Role of matrix metalloproteinases.

Eur J Heart Fail 2006 Nov 7;8(7):665-72. Epub 2006 Jul 7.

Institute of Physiology II, University of Bonn, Germany.

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http://dx.doi.org/10.1016/j.ejheart.2006.03.005DOI Listing
November 2006

Myocardial injury modulates the innate immune system and changes myocardial sensitivity.

Basic Res Cardiol 2006 Sep 12;101(5):427-35. Epub 2006 May 12.

Department of Anesthesiology and Intensive Care Medicine, Universitätsklinikum Bonn, Sigmund-Freud Strasse 25, 53105, Bonn, Germany.

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http://link.springer.com/10.1007/s00395-006-0597-0
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http://dx.doi.org/10.1007/s00395-006-0597-0DOI Listing
September 2006

Estrogen receptor beta protects the murine heart against left ventricular hypertrophy.

Arterioscler Thromb Vasc Biol 2006 Jul 20;26(7):1524-30. Epub 2006 Apr 20.

Department of Cardiology, Cardiovascular Research Institute Maastricht, University Hospital Maastricht, Netherlands.

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http://dx.doi.org/10.1161/01.ATV.0000223344.11128.23DOI Listing
July 2006

Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia.

Shock 2006 Jan;25(1):43-9

Department of Anesthesiology and Intensive Care Medicine, Institute of Physiology II, Universitätsklinikum Bonn, D-53111 Bonn, Germany.

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http://dx.doi.org/10.1097/01.shk.0000196498.57306.a6DOI Listing
January 2006

'Tib the balance': the search for the optimal hormone replacement therapy.

Authors:
Christian Grohé

Eur Heart J 2005 Jul 17;26(14):1345-6. Epub 2005 Jun 17.

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http://dx.doi.org/10.1093/eurheartj/ehi354DOI Listing
July 2005

17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling.

Circ Res 2004 Oct 2;95(7):692-9. Epub 2004 Sep 2.

Molecular Cardiology Research Institute, Department of Medicine, Tufts-New England Medical Center, 750 Washington St, Boston MA 02111, USA.

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http://dx.doi.org/10.1161/01.RES.0000144126.57786.89DOI Listing
October 2004

The cardiac cocaine connection.

Cardiovasc Res 2003 Oct;59(4):805-6

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http://dx.doi.org/10.1016/s0008-6363(03)00532-7DOI Listing
October 2003

17 Beta-estradiol regulates the expression of endothelin receptor type B in the heart.

Br J Pharmacol 2003 Sep 29;140(1):195-201. Epub 2003 Jul 29.

Institut für Physiologie II, Wilhelmstr. 35-37, Universitatsklinikum Bonn 53111, Germany.

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http://dx.doi.org/10.1038/sj.bjp.0705409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1574007PMC
September 2003

Modulation of antioxidant enzyme expression and function by estrogen.

Circ Res 2003 Jul 19;93(2):170-7. Epub 2003 Jun 19.

Medizinische Klinik und Poliklinik, Innere Medizin III, Universitätskliniken des Saarlandes, Homburg/Saar, Germany.

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http://dx.doi.org/10.1161/01.RES.0000082334.17947.11DOI Listing
July 2003

Increasing myocardial contraction and blood pressure in C57BL/6 mice during early postnatal development.

Am J Physiol Heart Circ Physiol 2003 Feb 31;284(2):H464-74. Epub 2002 Oct 31.

Department of Pharmacology, Universitätsklinik Bonn, Germany.

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http://dx.doi.org/10.1152/ajpheart.00540.2002DOI Listing
February 2003

Induction of atrial fibrillation in mice by rapid transesophageal atrial pacing.

Basic Res Cardiol 2002 Nov;97(6):452-60

Department of Cardiology, University of Bonn, Sigmund-Freud-Str 25, 53105 Bonn, Germany.

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http://dx.doi.org/10.1007/s003950200052DOI Listing
November 2002

Estrogenic hormone action in the heart: regulatory network and function.

Cardiovasc Res 2002 Feb;53(3):709-19

Department of Cardiology, Cardiovascular Research Institute Maastricht, University Hospital Maastricht, P. Debyelaan 25, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/s0008-6363(01)00526-0DOI Listing
February 2002