Publications by authors named "Christian Funck-Brentano"

131 Publications

Development and clinical validation of a simple and fast UPLC-ESI-MS/MS method for simultaneous quantification of nine kinase inhibitors and two antiandrogen drugs in human plasma: Interest for their therapeutic drug monitoring.

Authors:
Benoit Llopis Pascal Robidou Nadine Tissot Bruno Pinna Paul Gougis Fleur Cohen Aubart Luca Campedel Baptiste Abbar Damien Roos Weil Madalina Uzunov Joseph Gligorov Joe-Elie Salem Christian Funck-Brentano Noël Zahr

J Pharm Biomed Anal 2021 Feb 14;197:113968. Epub 2021 Feb 14.

AP-HP.Sorbonne Université, Department of Pharmacology and Clinical Investigation Center (CIC-1901), Pitié-Salpêtrière Hospital, INSERM, CIC-1901 and UMR-S 1166, Sorbonne Université, Faculty of Medicine Sorbonne Université, Faculty of Medicine, Paris, France. Electronic address:

View Article and Find Full Text PDF
February 2021

Pharmacokinetics and pharmacodynamics of hydroxychloroquine in hospitalized patients with COVID-19.

Authors:
Noël Zahr Saik Urien Benoit Llopis Valérie Pourcher Olivier Paccoud Alexandre Bleibtreu Julien Mayaux Estelle Gandjbakhch Guillaume Hekimian Alain Combes Olivier Benveniste David Saadoun Yves Allenbach Bruno Pinna Patrice Cacoub Christian Funck-Brentano Joe-Elie Salem

Therapie 2021 Jan 28. Epub 2021 Jan 28.

AP-HP, Sorbonne Université, Pitié-Salpêtrière Hospital, Department of Pharmacology and Clinical Investigation Center, INSERM, CIC-1901, Sorbonne Université, Faculty of Medicine, 75013 Paris, France.

View Article and Find Full Text PDF
January 2021

Sexual Dimorphisms, Anti-Hormonal Therapy and Cardiac Arrhythmias.

Authors:
Virginie Grouthier Melissa Y Y Moey Estelle Gandjbakhch Xavier Waintraub Christian Funck-Brentano Anne Bachelot Joe-Elie Salem

Int J Mol Sci 2021 Feb 2;22(3). Epub 2021 Feb 2.

INSERM, CIC-1901, AP-HP, Pitié-Salpêtrière Hospital, Regional Pharmacovigilance Center, UNICO-GRECO Cardio-Oncology Program, Department of Pharmacology and Clinical Investigation Center, CLIP2 Galilée, Sorbonne Université, F-75013 Paris, France.

View Article and Find Full Text PDF
February 2021

Cardiotoxicity Associated with Gemcitabine: Literature Review and a Pharmacovigilance Study.

Authors:
Marc Hilmi Stéphane Ederhy Xavier Waintraub Christian Funck-Brentano Ariel Cohen Aurore Vozy Bénédicte Lebrun-Vignes Javid Moslehi Lee S Nguyen Joe-Elie Salem

Pharmaceuticals (Basel) 2020 Oct 21;13(10). Epub 2020 Oct 21.

Department of Pharmacology, Regional Pharmacovigilance Centre, Pitié-Salpêtrière Hospital, INSERM CIC-1901, Sorbonne Université, AP-HP, 75006 Paris, France.

View Article and Find Full Text PDF
October 2020

Indispensable but deceptive evidence-based medicine.

Authors:
Christian Funck-Brentano

Diabetes Metab 2020 11 10;46(6):415-422. Epub 2020 Oct 10.

AP-HP Sorbonne Université, Pitié-Salpêtrière University Hospital, Department of Pharmacology and Clinical Investigation Centre, F-75013 Paris, France; INSERM, CIC-1901 and UMR-S 1166, Sorbonne University, Faculty of Medicine, F-75013 Paris, France. Electronic address:

View Article and Find Full Text PDF
November 2020

Circulating Receptor Activator of Nuclear Factor kB Ligand and triglycerides are associated with progression of lower limb arterial calcification in type 2 diabetes: a prospective, observational cohort study.

Authors:
Olivier Bourron Franck Phan Mamadou Hassimiou Diallo David Hajage Carole-Elodie Aubert Aurélie Carlier Joe-Elie Salem Christian Funck-Brentano Salim Kemel Philippe Cluzel Alban Redheuil Jean-Michel Davaine Ziad Massy Romuald Mentaverri Dominique Bonnefont-Rousselot Philippe Gillery Stéphane Jaisson Cees Vermeer Jean-Marc Lacorte Nesrine Bouziri Suzanne Laroche Chloé Amouyal Agnes Hartemann

Cardiovasc Diabetol 2020 09 18;19(1):140. Epub 2020 Sep 18.

Sorbonne Université, Paris, France.

View Article and Find Full Text PDF
September 2020

HIV Infection and Long-Term Residual Cardiovascular Risk After Acute Coronary Syndrome.

Authors:
Franck Boccara Murielle Mary-Krause Valérie Potard Emmanuel Teiger Sylvie Lang Nadjib Hammoudi Marion Chauvet Stéphane Ederhy Laurie Dufour-Soulat Yann Ancedy Pascal Nhan Saroumadi Adavane Ph Gabriel Steg Christian Funck-Brentano Dominique Costagliola Ariel Cohen

J Am Heart Assoc 2020 09 26;9(17):e017578. Epub 2020 Aug 26.

Department of Cardiology Faculty of Medicine AP-HP Hôpitaux de l'Est Parisien Hôpital Saint-Antoine Sorbonne Université Paris France.

View Article and Find Full Text PDF
September 2020

Retraction and republication: cardiac toxicity of hydroxychloroquine in COVID-19.

Authors:
Christian Funck-Brentano Lee S Nguyen Joe-Elie Salem

Lancet 2020 07 9;396(10245):e2-e3. Epub 2020 Jul 9.

AP-HP, Sorbonne Université, Pitié-Salpêtrière Hospital, Department of Pharmacology and Clinical Investigation Centre, Paris 75013, France; INSERM, CIC-1901 and UMR-S 1166, Sorbonne Université, Faculty of Medicine, Paris, France.

View Article and Find Full Text PDF
July 2020

Anticancer drugs and COVID-19 antiviral treatments in patients with cancer: What can we safely use?

Authors:
Paul Gougis Charlotte Fenioux Christian Funck-Brentano Marianne Veyri Joseph Gligorov Caroline Solas Jean-Philippe Spano

Eur J Cancer 2020 09 10;136:1-3. Epub 2020 Jun 10.

Sorbonne Université, Assistance Publique - Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Department of Oncology, F-75013 Paris, France; Institut Universitaire de Cancérologie. AP-HP Sorbonne Université, Paris, France; INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, équipe Theravir, France.

View Article and Find Full Text PDF
September 2020

Effect of congenital adrenal hyperplasia treated by glucocorticoids on plasma metabolome: a machine-learning-based analysis.

Authors:
Lee S Nguyen Edi Prifti Farid Ichou Monique Leban Christian Funck-Brentano Philippe Touraine Joe-Elie Salem Anne Bachelot

Sci Rep 2020 06 1;10(1):8859. Epub 2020 Jun 1.

Department of Endocrinology and Reproductive Medicine, Sorbonne Université, AP-HP, Pitié-Salpêtrière Hospital, Centre de Référence des Maladies Endocriniennes Rares de la Croissance, Centre de Référence des Pathologies Gynécologiques Rares, ICAN, Paris, France.

View Article and Find Full Text PDF
June 2020

Chloroquine or hydroxychloroquine for COVID-19: why might they be hazardous?

Authors:
Christian Funck-Brentano Joe-Elie Salem

Lancet 2020 05 22. Epub 2020 May 22.

AP-HP, Sorbonne Université, Pitié-Salpêtrière Hospital, Department of Pharmacology and Clinical Investigation Centre, Paris 75013, France; INSERM, CIC-1901 and UMR-S 1166, Sorbonne Université, Faculty of Medicine, Paris, France.

View Article and Find Full Text PDF
May 2020

Cardiovascular Toxicities Associated With Hydroxychloroquine and Azithromycin: An Analysis of the World Health Organization Pharmacovigilance Database.

Authors:
Lee S Nguyen Charles Dolladille Milou-Daniel Drici Charlotte Fenioux Joachim Alexandre Jean-Paul Mira Javid J Moslehi Dan M Roden Christian Funck-Brentano Joe-Elie Salem

Circulation 2020 Jul 22;142(3):303-305. Epub 2020 May 22.

Sorbonne Université, Institut national de la santé et de la recherche médicale (INSERM), Assistance Publique - Hopitaux de Paris, Clinical Investigation Center, Department of Pharmacology, Pitié-Salpêtrière Hospital, Paris, France (L.S.N., C.F., C.F.-B., J.-E.S.).

View Article and Find Full Text PDF
July 2020

Correction: Inactive matrix gla protein plasma levels are associated with peripheral neuropathy in Type 2 diabetes.

Authors:
Anne-Caroline Jeannin Joe-Elie Salem Ziad Massy Carole Elodie Aubert Cees Vemeer Chloé Amouyal Franck Phan Marine Halbron Christian Funck-Brentano Agnès Hartemann Olivier Bourron

PLoS One 2020 5;15(5):e0232996. Epub 2020 May 5.

View Article and Find Full Text PDF
May 2020

Identification of anticancer drugs associated with atrial fibrillation - analysis of the WHO pharmacovigilance database.

Authors:
Joachim Alexandre Joe-Elie Salem Javid Moslehi Marion Sassier Camille Ropert Jennifer Cautela Franck Thuny Stéphane Ederhy Ariel Cohen Ghandi Damaj Jean-Pierre Vilque Anne-Flore Plane Damien Legallois Laure Champ-Rigot Paul Milliez Christian Funck-Brentano Charles Dolladille

Eur Heart J Cardiovasc Pharmacother 2020 Apr 30. Epub 2020 Apr 30.

Normandie Univ, UNICAEN, CHU de Caen Normandie, PICARO Cardio-oncology Program, Department of Pharmacology, EA 4650, Signalisation, électrophysiologie et imagerie des lésions d'ischémie-reperfusion myocardique, F-14000 CAEN, France.

View Article and Find Full Text PDF
April 2020

Response to the editorial "COVID-19 in patients with cardiovascular diseases": Covid-19 treatment with hydroxychloroquine or chloroquine and azithromycin: A potential risk of Torsades de Pointes.

Authors:
Christian Funck-Brentano Joe-Elie Salem Lee S Nguyen Milou-Daniel Drici Dan M Roden

Arch Cardiovasc Dis 2020 05 15;113(5):367-368. Epub 2020 Apr 15.

Department of Medicine, Vanderbilt University Medical Centre, Nashville, TN, USA.

View Article and Find Full Text PDF
May 2020

Randomized study of the effect of gadopiclenol, a new gadolinium-based contrast agent, on the QTc interval in healthy subjects.

Authors:
Christian Funck-Brentano Mathieu Felices Nathalie Le Fur Corinne Dubourdieu Pierre Desché Frédéric Vanhoutte Pascal Voiriot

Br J Clin Pharmacol 2020 11 27;86(11):2174-2181. Epub 2020 Apr 27.

Cardiabase, Nancy, France.

View Article and Find Full Text PDF
November 2020

Uses of pharmacovigilance databases: An overview.

Authors:
Kévin Bihan Bénédicte Lebrun-Vignes Christian Funck-Brentano Joe-Elie Salem

Therapie 2020 Nov - Dec;75(6):591-598. Epub 2020 Feb 26.

INSERM, CIC Pitié-Salpêtrière (CIC-1901), Sorbonne université, faculty of medicine, AP-HP, Pitié-Salpêtrière hospital, department of pharmacology and clinical investigation center, UNICO-GRECO Cardio-oncology program, 75013 Paris, France.

View Article and Find Full Text PDF
February 2020

Inactive matrix gla protein plasma levels are associated with peripheral neuropathy in Type 2 diabetes.

Authors:
Anne-Caroline Jeannin Joe-Elie Salem Ziad Massy Carole Elodie Aubert Cees Vermeer Chloé Amouyal Franck Phan Marine Halbron Christian Funck-Brentano Agnès Hartemann Olivier Bourron

PLoS One 2020 24;15(2):e0229145. Epub 2020 Feb 24.

Sorbonne Université, Paris, France.

View Article and Find Full Text PDF
June 2020

Development and validation of a UPLC-MS/MS method for simultaneous quantification of levofloxacin, ciprofloxacin, moxifloxacin and rifampicin in human plasma: Application to the therapeutic drug monitoring in osteoarticular infections.

Authors:
Benoit LLopis Christian Funck-Brentano Nadine Tissot Alexandre Bleibtreu Stéphane Jaureguiberry Eric Fourniols Alexandra Aubry Noël Zahr

J Pharm Biomed Anal 2020 May 1;183:113137. Epub 2020 Feb 1.

AP-HP, Pitié-Salpêtrière Hospital, Department of Pharmacology, CIC-1421, F-75013 Paris, France. Electronic address:

View Article and Find Full Text PDF
May 2020

Response by Salem et al to Letter Regarding Article, "Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes".

Authors:
Joe-Elie Salem Javid J Moslehi Christian Funck Brentano Dan M Roden

Circulation 2020 02 3;141(5):e63-e64. Epub 2020 Feb 3.

Department of Medicine and Pharmacology, Cardio-Oncology Program (J.-E.S., J.J.M., D.M.R.), Vanderbilt University Medical Center, Nashville, TN.

View Article and Find Full Text PDF
February 2020

Results of the 2017 inspection campaign of French phase I/II research sites in Île-de-France following the BIA 10-2474 accident: Medical vs. regulatory relevance.

Authors:
Claire Henry Franck Odoul Coffi Megnigbeto Bruno Lebourgeois François Doz Christian Funck-Brentano

Therapie 2020 Nov - Dec;75(6):517-525. Epub 2020 Jan 14.

INSERM, CIC-1901 and UMR ICAN 1166, Sorbonne university, faculty of medicine, AP-HP, Pitié-Salpêtrière hospital, department of pharmacology and clinical investigation center Paris-Est, institute of cardiometabolism and nutrition (ICAN), 75013 Paris, France. Electronic address:

View Article and Find Full Text PDF
January 2020

Anti-ischaemic medication must be adapted to each patient's characteristics and preferences in patients with chronic coronary syndromes.

Authors:
Juhani Knuuti William Wijns Christian Funck-Brentano

Eur Heart J 2020 01;41(3):480-481

Department of Clinical Pharmacology, Sorbonne Université, INSERM CIC Paris-Est, AP-HP.Sorbonne Université, ICAN, Pitié-Salpêtrière Hospital, 47-83 Blvd de l'Hôpital, F-75013 Paris, France.

View Article and Find Full Text PDF
January 2020

Effects of Mineralocorticoid Receptor Antagonists on Atrial Fibrillation Occurrence: A Systematic Review, Meta-Analysis, and Meta-Regression to Identify Modifying Factors.

Authors:
Joachim Alexandre Charles Dolladille Laurent Douesnel Jonaz Font Rafal Dabrowski Linda Shavit Damien Legallois Christian Funck-Brentano Laure Champ-Rigot Pierre Ollitrault Farzin Beygui Theodora Bejan-Angoulvant Jean-Jacques Parienti Paul Milliez

J Am Heart Assoc 2019 11 12;8(22):e013267. Epub 2019 Nov 12.

UNICAEN, CHU Caen Medical School Université Caen Normandie Caen France.

View Article and Find Full Text PDF
November 2019

Heart failure and atrial tachyarrhythmia on abiraterone: A pharmacovigilance study.

Authors:
Marie Bretagne Bénédicte Lebrun-Vignes Antoine Pariente Christian M Shaffer Gabriel G Malouf Pauline Dureau Camille Potey Christian Funck-Brentano Dan M Roden Javid J Moslehi Joe-Elie Salem

Arch Cardiovasc Dis 2020 Jan 2;113(1):9-21. Epub 2019 Nov 2.

Department of pharmacology, Sorbonne université, Inserm CIC Paris-Est, ICAN, UNICO-GRECO, Sorbonne Cardio-Oncology program, regional pharmacovigilance centre, Pitié-Salpêtrière hospital, AP-HP, 75013 Paris, France; Cardio-oncology program, department of medicine and pharmacology, Vanderbilt university medical center, 37232 Nashville, TN, USA. Electronic address:

View Article and Find Full Text PDF
January 2020

[Early clinical drug development].

Authors:
Christian Funck-Brentano

Rev Prat 2019 Jun;69(6):607-611

Sorbonne université, Inserm CIC Paris-Est, AP-HP, ICAN, service de pharmacologie médicale, groupe hospitalier La Pitié-Salpêtrière, Paris, France.

View Article and Find Full Text PDF
June 2019

Cardiovascular Toxicities Associated With Ibrutinib.

Authors:
Joe-Elie Salem Ali Manouchehri Marie Bretagne Bénédicte Lebrun-Vignes John D Groarke Douglas B Johnson Tao Yang Nishitha M Reddy Christian Funck-Brentano Jennifer R Brown Dan M Roden Javid J Moslehi

J Am Coll Cardiol 2019 10;74(13):1667-1678

Departments of Medicine and Pharmacology, Cardio-Oncology program, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

View Article and Find Full Text PDF
October 2019

Influence of hormones on the immunotolerogenic molecule HLA-G: a cross-sectional study in patients with congenital adrenal hyperplasia.

Authors:
Lee S Nguyen Nathalie Rouas-Freiss Christian Funck-Brentano Monique Leban Edgardo D Carosella Philippe Touraine Shaida Varnous Anne Bachelot Joe-Elie Salem

Eur J Endocrinol 2019 Nov;181(5):481-488

Department of Pharmacology, Sorbonne Université, INSERM CIC Paris-Est, UNICO AP-HP.6 Cardio-Oncology Program, Pitié-Salpêtrière Hospital, Paris, France.

View Article and Find Full Text PDF
November 2019

2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes.

Authors:
Juhani Knuuti William Wijns Antti Saraste Davide Capodanno Emanuele Barbato Christian Funck-Brentano Eva Prescott Robert F Storey Christi Deaton Thomas Cuisset Stefan Agewall Kenneth Dickstein Thor Edvardsen Javier Escaned Bernard J Gersh Pavel Svitil Martine Gilard David Hasdai Robert Hatala Felix Mahfoud Josep Masip Claudio Muneretto Marco Valgimigli Stephan Achenbach Jeroen J Bax

Eur Heart J 2020 01;41(3):407-477

View Article and Find Full Text PDF
January 2020

Clinical characterization of men with long QT syndrome and torsades de pointes associated with hypogonadism: A review and pharmacovigilance study.

Authors:
Joe-Elie Salem Marie Bretagne Benedicte Lebrun-Vignes Xavier Waintraub Estelle Gandjbakhch Francoise Hidden-Lucet Paul Gougis Anne Bachelot Christian Funck-Brentano

Arch Cardiovasc Dis 2019 Nov 30;112(11):699-712. Epub 2019 Aug 30.

Inserm, UNICO-GRECO Cardio-Oncology Programme, Department of Pharmacology, CIC-1421, Pharmacovigilance Unit, Pitié-Salpêtrière Hospital, Sorbonne Université, AP-HP, 75013 Paris, France.

View Article and Find Full Text PDF
November 2019

Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes.

Authors:
Joe-Elie Salem Tao Yang Javid J Moslehi Xavier Waintraub Estelle Gandjbakhch Anne Bachelot Francoise Hidden-Lucet Jean-Sebastien Hulot Bjorn C Knollmann Benedicte Lebrun-Vignes Christian Funck-Brentano Andrew M Glazer Dan M Roden

Circulation 2019 09 5;140(13):1070-1080. Epub 2019 Aug 5.

Department of Medicine (J-E.S., T.Y., J.J.M., B.C.K., A.M.G., D.M.R.), Vanderbilt University Medical Center, Nashville, TN.

View Article and Find Full Text PDF
September 2019
Get 20% Off Journals at LWW.com