Christian Drosten

Christian Drosten

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Christian Drosten

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The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health - The latest 2019 novel coronavirus outbreak in Wuhan, China.

Int J Infect Dis 2020 Feb 14;91:264-266. Epub 2020 Jan 14.

Directorate General for Disease Surveillance and Control, Ministry of Health, Muscat, Oman; Institute for Clinical Medicine, Faculty of Health Science, University of Aarhus, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.ijid.2020.01.009DOI Listing
February 2020

Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence.

Elife 2020 Feb 3;9. Epub 2020 Feb 3.

Department of Coastal Systems, Royal Netherlands Institute for Sea Research, Texel, Netherlands.

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http://dx.doi.org/10.7554/eLife.48401DOI Listing
February 2020

The Middle East Respiratory Syndrome (MERS).

Infect Dis Clin North Am 2019 12;33(4):891-905

Center for Clinical Microbiology, University College London, Royal Free Campus 2nd Floor, Rowland Hill Street, London NW3 2PF, United Kingdom.

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http://dx.doi.org/10.1016/j.idc.2019.08.001DOI Listing
December 2019

Re-assessing the diversity of negative strand RNA viruses in insects.

PLoS Pathog 2019 Dec 12;15(12):e1008224. Epub 2019 Dec 12.

Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Free University, Humboldt-University and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1008224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932829PMC
December 2019

Enzootic patterns of Middle East respiratory syndrome coronavirus in imported African and local Arabian dromedary camels: a prospective genomic study.

Lancet Planet Health 2019 Dec 16;3(12):e521-e528. Epub 2019 Dec 16.

Special Infectious Agent Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/S2542-5196(19)30243-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926486PMC
December 2019

Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience.

Antivir Ther 2018 20;23(7):617-622. Epub 2018 Jun 20.

Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.3851/IMP3243DOI Listing
September 2019

Virus- and Interferon Alpha-Induced Transcriptomes of Cells from the Microbat Myotis daubentonii.

iScience 2019 Sep 10;19:647-661. Epub 2019 Aug 10.

Institute for Virology, FB10-Veterinary Medicine, Justus-Liebig University, Giessen, Germany; Institute for Virology, Philipps University Marburg, Marburg, Germany; German Centre for Infection Research (DZIF), partner sites Marburg, Giessen, and Charité Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718828PMC
September 2019

Detection of Two Highly Diverse Peribunyaviruses in Mosquitoes from Palenque, Mexico.

Viruses 2019 Sep 7;11(9). Epub 2019 Sep 7.

Berlin Institute of Health, Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, 10117 Berlin, Germany.

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http://dx.doi.org/10.3390/v11090832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783978PMC
September 2019

Adenovirus infection is associated with altered gut microbial communities in a non-human primate.

Sci Rep 2019 Sep 16;9(1):13410. Epub 2019 Sep 16.

University of Ulm, Institute of Evolutionary Ecology and Conservation Genomics, Ulm, Germany.

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http://dx.doi.org/10.1038/s41598-019-49829-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746978PMC
September 2019

A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species.

Proc Natl Acad Sci U S A 2019 Jun 21;116(23):11351-11360. Epub 2019 May 21.

BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303;

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http://dx.doi.org/10.1073/pnas.1814995116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561249PMC
June 2019

Huge diversity of phleboviruses in ticks from Strandja Nature Park, Bulgaria.

Ticks Tick Borne Dis 2019 04 5;10(3):697-703. Epub 2019 Mar 5.

Institute of Virology, Charité Universitätsmedizin Berlin, Corporate Member of Free University Berlin, Humboldt-University Berlin, and Berlin Institute of Health, Berlin, Germany; German Centre for Infection Research (DZIF), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ttbdis.2019.03.001DOI Listing
April 2019

The difficulties in obtaining reliable Zika virus diagnostics.

Lancet Infect Dis 2019 Mar;19(3):240-241

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin 10117, Germany; German Centre for Infection Research, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30049-0DOI Listing
March 2019

Corrigendum to "Phylogenetic analysis of a newfound bat-borne hantavirus supports a Laurasiatherian host association for ancestral mammalian hantaviruses" [Infect. Genet. Evol. 41 (2016) 113-119].

Infect Genet Evol 2019 01 26;67:245. Epub 2018 Apr 26.

Institute of Virology, Helmut-Ruska-Haus, Charité Medical School, Berlin, Germany; Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia. Electronic address:

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http://dx.doi.org/10.1016/j.meegid.2018.02.033DOI Listing
January 2019

Hosts and Sources of Endemic Human Coronaviruses.

Adv Virus Res 2018 16;100:163-188. Epub 2018 Feb 16.

Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin, Germany; German Center for Infection Research (DZIF), Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00653527183000
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http://dx.doi.org/10.1016/bs.aivir.2018.01.001DOI Listing
December 2018

Astrovirus infections induce age-dependent dysbiosis in gut microbiomes of bats.

ISME J 2018 12 30;12(12):2883-2893. Epub 2018 Jul 30.

Institute of Evolutionary Ecology and Conservation Genomics, University of Ulm, Albert-Einstein Allee 11, Ulm, D-89069, Germany.

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http://dx.doi.org/10.1038/s41396-018-0239-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246552PMC
December 2018

Zika virus infection in human placental tissue explants is enhanced in the presence of dengue virus antibodies in-vitro.

Emerg Microbes Infect 2018 Dec 1;7(1):198. Epub 2018 Dec 1.

Institute of Virology, Campus Charité Mitte, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1038/s41426-018-0199-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274641PMC
December 2018

Ecological drivers of Hepacivirus infection in a neotropical rodent inhabiting landscapes with various degrees of human environmental change.

Oecologia 2018 Sep 23;188(1):289-302. Epub 2018 Jun 23.

Institute of Evolutionary Ecology and Conservation Genomics, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1007/s00442-018-4210-7DOI Listing
September 2018

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species.

PLoS Pathog 2018 09 24;14(9):e1007296. Epub 2018 Sep 24.

Institute of Virology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1007296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171950PMC
September 2018

Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018.

Authors:
Piet Maes Sergey V Alkhovsky Yīmíng Bào Martin Beer Monica Birkhead Thomas Briese Michael J Buchmeier Charles H Calisher Rémi N Charrel Il Ryong Choi Christopher S Clegg Juan Carlos de la Torre Eric Delwart Joseph L DeRisi Patrick L Di Bello Francesco Di Serio Michele Digiaro Valerian V Dolja Christian Drosten Tobiasz Z Druciarek Jiang Du Hideki Ebihara Toufic Elbeaino Rose C Gergerich Amethyst N Gillis Jean-Paul J Gonzalez Anne-Lise Haenni Jussi Hepojoki Udo Hetzel Thiện Hồ Ní Hóng Rakesh K Jain Petrus Jansen van Vuren Qi Jin Miranda Gilda Jonson Sandra Junglen Karen E Keller Alan Kemp Anja Kipar Nikola O Kondov Eugene V Koonin Richard Kormelink Yegor Korzyukov Mart Krupovic Amy J Lambert Alma G Laney Matthew LeBreton Igor S Lukashevich Marco Marklewitz Wanda Markotter Giovanni P Martelli Robert R Martin Nicole Mielke-Ehret Hans-Peter Mühlbach Beatriz Navarro Terry Fei Fan Ng Márcio Roberto Teixeira Nunes Gustavo Palacios Janusz T Pawęska Clarence J Peters Alexander Plyusnin Sheli R Radoshitzky Víctor Romanowski Pertteli Salmenperä Maria S Salvato Hélène Sanfaçon Takahide Sasaya Connie Schmaljohn Bradley S Schneider Yukio Shirako Stuart Siddell Tarja A Sironen Mark D Stenglein Nadia Storm Harikishan Sudini Robert B Tesh Ioannis E Tzanetakis Mangala Uppala Olli Vapalahti Nikos Vasilakis Peter J Walker Guópíng Wáng Lìpíng Wáng Yànxiăng Wáng Tàiyún Wèi Michael R Wiley Yuri I Wolf Nathan D Wolfe Zhìqiáng Wú Wénxìng Xú Li Yang Zuòkūn Yāng Shyi-Dong Yeh Yǒng-Zhèn Zhāng Yàzhōu Zhèng Xueping Zhou Chénxī Zhū Florian Zirkel Jens H Kuhn

Arch Virol 2018 Aug 21;163(8):2295-2310. Epub 2018 Apr 21.

Division of Clinical Research (DCR), Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), B-8200 Research Plaza, Fort Detrick, Frederick, MD, 21702, USA.

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http://dx.doi.org/10.1007/s00705-018-3843-5DOI Listing
August 2018

A novel hepatitis B virus species discovered in capuchin monkeys sheds new light on the evolution of primate hepadnaviruses.

J Hepatol 2018 06 8;68(6):1114-1122. Epub 2018 Feb 8.

Institute of Virology, University of Bonn Medical Centre, Bonn, Germany; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Berlin, Germany; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Virology, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.01.029DOI Listing
June 2018

Intravesical cidofovir application in BK virus cystitis after allogeneic hematopoetic stem cell transplantation (HSCT) is safe and highly effective.

Bone Marrow Transplant 2018 04 12;53(4):495-498. Epub 2018 Jan 12.

Medical Clinic III for Oncology, Hematology, Immunoncology and Rheumatology, University Hospital Bonn (UKB), Bonn, Germany.

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http://dx.doi.org/10.1038/s41409-017-0044-xDOI Listing
April 2018

Serologic responses of 42 MERS-coronavirus-infected patients according to the disease severity.

Diagn Microbiol Infect Dis 2017 Oct 14;89(2):106-111. Epub 2017 Jul 14.

Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.diagmicrobio.2017.07.006DOI Listing
October 2017

Seasonal Fluctuations of Astrovirus, But Not Coronavirus Shedding in Bats Inhabiting Human-Modified Tropical Forests.

Ecohealth 2017 06 12;14(2):272-284. Epub 2017 May 12.

Department of Evolutionary Ecology, Leibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke-Str. 17, 10315, Berlin, Germany.

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http://dx.doi.org/10.1007/s10393-017-1245-xDOI Listing
June 2017

Serologic Evaluation of MERS Screening Strategy for Healthcare Personnel During a Hospital-Associated Outbreak.

Infect Control Hosp Epidemiol 2017 02 14;38(2):234-238. Epub 2016 Nov 14.

1Division of Infectious Diseases,Department of Medicine,Samsung Medical Center,Sungkyunkwan University School of Medicine,Seoul 135-710,Korea.

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http://dx.doi.org/10.1017/ice.2016.251DOI Listing
February 2017

Discovery of a novel alphavirus related to Eilat virus.

J Gen Virol 2017 Jan;98(1):43-49

Institute of Virology, University of Bonn Medical Centre, Bonn, Germany.

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http://dx.doi.org/10.1099/jgv.0.000694DOI Listing
January 2017

Zika virus and congenital malformations in perspective.

Euro Surveill 2016 ;21(13)

Institute of Virology, University of Bonn, Germany.

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http://dx.doi.org/10.2807/1560-7917.ES.2016.21.13.30182DOI Listing
December 2016

Fatal outcome of human coronavirus NL63 infection despite successful viral elimination by IFN-alpha in a patient with newly diagnosed ALL.

Eur J Haematol 2016 Aug 4;97(2):208-210. Epub 2016 Mar 4.

Medical Clinic III for Oncology, Haematology and Rheumatology, University Hospital Bonn (UKB), Bonn, Germany.

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http://dx.doi.org/10.1111/ejh.12744DOI Listing
August 2016

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1.

Proc Natl Acad Sci U S A 2016 08 12;113(35):E5192-201. Epub 2016 Aug 12.

Max-von-Pettenkofer Institute, Ludwig-Maximilians-University Munich and German Center for Infection Research (DZIF), partner site Munich, 80336 Munich, Germany;

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http://dx.doi.org/10.1073/pnas.1603435113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024628PMC
August 2016

Phylogenetic analysis of a newfound bat-borne hantavirus supports a laurasiatherian host association for ancestral mammalian hantaviruses.

Infect Genet Evol 2016 07 3;41:113-119. Epub 2016 Apr 3.

Institute of Virology, Helmut-Ruska-Haus, Charité Medical School, Berlin, Germany; Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia.

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http://dx.doi.org/10.1016/j.meegid.2016.03.036DOI Listing
July 2016

Serological evidence of influenza A viruses in frugivorous bats from Africa.

PLoS One 2015 12;10(5):e0127035. Epub 2015 May 12.

Center for Infectious Diseases Research, Diagnostics and Screening, Department of Virology, National Institute for Public Health and the Environment, Bilthoven, the Netherlands; Viroscience Department, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127035PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429104PMC
February 2016

Editorial overview: Emerging viruses: Interspecies transmission.

Curr Opin Virol 2016 Feb;16:v-vi

Mitentdeckern of the SARS Virus, Institute of Virology at the University Hospital Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2016.03.005DOI Listing
February 2016

Lagos bat virus transmission in an Eidolon helvum bat colony, Ghana.

Virus Res 2015 Dec 17;210:42-5. Epub 2015 Jul 17.

Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Molecular Virology and Cell Biology, WHO Collaborating Centre for Rabies Surveillance and Research, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1016/j.virusres.2015.07.009DOI Listing
December 2015

Evolutionary origins of hepatitis A virus in small mammals.

Proc Natl Acad Sci U S A 2015 Dec 2;112(49):15190-5. Epub 2015 Nov 2.

Institute of Virology, University of Bonn Medical Centre, 53127 Bonn, Germany; German Centre for Infection Research, Bonn-Cologne, Germany;

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http://dx.doi.org/10.1073/pnas.1516992112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679062PMC
December 2015

First international external quality assessment of molecular diagnostics for Mers-CoV.

J Clin Virol 2015 Aug 30;69:81-5. Epub 2015 May 30.

Center for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jcv.2015.05.022DOI Listing
August 2015

Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family.

Proc Natl Acad Sci U S A 2015 Jun 2;112(24):7536-41. Epub 2015 Jun 2.

Institute of Virology, University of Bonn Medical Center, 53127 Bonn, Germany; German Center for Infection Research, Partner Site Bonn-Cologne, 53127 Bonn, Germany;

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http://dx.doi.org/10.1073/pnas.1502036112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475995PMC
June 2015