Christian Brandts

Christian Brandts

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Christian Brandts

Christian Brandts

Publications by authors named "Christian Brandts"

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Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy.

PLoS One 2019 30;14(9):e0223013. Epub 2019 Sep 30.

Department of Medicine, Hematology/Oncology, Goethe University, Theodor-Stern-Kai, Frankfurt/Main, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223013PLOS
September 2019

Selective Autophagy in Normal and Malignant Hematopoiesis.

J Mol Biol 2019 Jun 28. Epub 2019 Jun 28.

Department of Medicine, Hematology/Oncology, Goethe University, Frankfurt, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany; University Cancer Center Frankfurt (UCT), Goethe University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2019.06.025DOI Listing
June 2019

Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation.

Cell Rep 2019 May;27(7):2022-2028.e3

Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt am Main 60590, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193053
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http://dx.doi.org/10.1016/j.celrep.2019.04.064DOI Listing
May 2019

Biglycan is a new high-affinity ligand for CD14 in macrophages.

Matrix Biol 2019 04 17;77:4-22. Epub 2018 May 17.

Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Klinikum der Goethe-Universität Frankfurt am Main, Frankfurt am Main 60590, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.05.006DOI Listing
April 2019

Innovating the outreach of comprehensive cancer centers.

Mol Oncol 2019 03 2;13(3):619-623. Epub 2019 Feb 2.

Department of Medicine, Hematology/Oncology, University Hospital Frankfurt, University Cancer Center Frankfurt (UCT), Germany.

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http://dx.doi.org/10.1002/1878-0261.12451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396353PMC
March 2019

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2).

Biochem J 2019 Mar 12;476(5):875-887. Epub 2019 Mar 12.

Institute of Pharmaceutical Chemistry, Goethe-University Frankfurt, 60438 Frankfurt, Germany

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http://dx.doi.org/10.1042/BCJ20190038DOI Listing
March 2019

Clinical Impact of Colonization with Multidrug-Resistant Organisms on Outcome after Autologous Stem Cell Transplantation: A Retrospective Single-Center Study.

Biol Blood Marrow Transplant 2017 Sep 18;23(9):1455-1462. Epub 2017 May 18.

Department of Hematology and Oncology, Johann Wolfgang Goethe University of Frankfurt, Frankfurt am Main, Germany; University Center for Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2017.05.016DOI Listing
September 2017

Improved Outcomes With Retinoic Acid and Arsenic Trioxide Compared With Retinoic Acid and Chemotherapy in Non-High-Risk Acute Promyelocytic Leukemia: Final Results of the Randomized Italian-German APL0406 Trial.

J Clin Oncol 2017 Feb 31;35(6):605-612. Epub 2016 Oct 31.

Uwe Platzbecker, Christian Thiede, Christoph Röllig, and Gerhard Ehninger, Universitätsklinikum Carl Gustav Carus der Technischen Universität Dresden; Uwe Platzbecker and Gerhard Ehninger, Study Alliance Leukemia, Dresden; Walter Fiedler, University Hospital Hamburg-Eppendorf; Norbert Schmitz, Asklepios Klinik St Georg Hamburg, Hamburg; Peter Brossart, Innere Medizin mit deSchwerpunkten Onkologie, Haematollogie un Rheumatologie, Bonn; Bernd Hertenstein, Klinikum Bremen Mitte, Bremen; Helmut R. Salih, University Hospital Tubingen; Mohammed Wattad, Kliniken Essen Süd, Essen; Michael Lübbert, University Medical Center, Freiburg; Christian H. Brandts, Goethe University Frankfurt, Frankfurt; Mathias Hänel, Klinikum Chemnitz gGmbH, Chemnitz; Hartmut Link, Klinik für Innere Medizin I, Westpfalz-Klinikum, Kaiserslautern; Konstanze Döhner, Hartmut Döhner, and Richard F. Schlenk, University Hospital Ulm, Ulm; Arnold Ganser, Hannover Medical School, Hannover, Germany; Giuseppe Avvisati, University Campus Bio-Medico; Laura Cicconi, Mariadomenica Divona, Sergio Amadori, and Francesco Lo-Coco, University Tor Vergata; Francesca Paoloni, Marco Vignetti, Fabio Efficace, Paola Fazi, and Franco Mandelli, Gruppo Italiano Malattie Ematologiche dell'Adulto Central Office; Marco Vignetti and Massimo Breccia, Sapienza University, Rome; Felicetto Ferrara, Cardarelli Hospital, Naples; Francesco Albano, University of Bari, Bari; Marco Sborgia, U.O. di Ematologia Clinica, Pescara; Eros Di Bona, San Bortolo Hospital, Vicenza; Erika Borlenghi, U.O. di Ematologia, Spedali Civili, Brescia; Roberto Cairoli, Ospedale Niguarda, Ca' Granda, SC Ematologia; Agostino Cortelezzi, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico and University of Milan, Milano; Alessandro Rambaldi, Azienda Opsedaliera Papa Giovanni XXIII, Bergamo; Lorella Melillo, Casa Sollievo della Sofferenza Hospital, IRCCS, San Giovanni Rotondo; Giorgio La Nasa, Centro Trapianti Midollo Osseo, Ospedale R. Binaghi, Università di Cagliari, Cagliari; Chiara Frairia, Hematology, Città della Salute e della Scienza, Torino; Enrico Maria Pogliani, Ospedale San Gerardo, Università degli Studi Milano Bicocca, Monza; Claudio Fozza, University of Sassari, Sassari; Alfonso Maria D'Arco, U.O. Medicina Interna e Onco-Ematologica P.O. "Umberto I," Nocera Inferiore, Nocera Inferiore; Nicola Di Renzo, Ospedale Vito Fazzi, Lecce; and Francesco Fabbiano, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy.

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http://dx.doi.org/10.1200/JCO.2016.67.1982DOI Listing
February 2017

The Phosphatases STS1 and STS2 Regulate Hematopoietic Stem and Progenitor Cell Fitness.

Stem Cell Reports 2015 Oct 10;5(4):633-46. Epub 2015 Sep 10.

Department of Medicine, Hematology/Oncology, Goethe University, 60590 Frankfurt, Germany; German Cancer Consortium, 69120 Heidelberg, Germany; German Cancer Research Center, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624938PMC
October 2015

Interferon-γ impairs proliferation of hematopoietic stem cells in mice.

Blood 2013 May 13;121(18):3578-85. Epub 2013 Mar 13.

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2012-05-432906DOI Listing
May 2013

Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling.

Exp Hematol 2011 May 1;39(5):591-600. Epub 2011 Mar 1.

Department of Medicine, Hematology/Oncology, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.exphem.2011.02.001DOI Listing
May 2011

Adaptor protein Lnk inhibits c-Fms-mediated macrophage function.

J Leukoc Biol 2010 Oct 22;88(4):699-706. Epub 2010 Jun 22.

Department of Hematology and Oncology, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1189/jlb.0309185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218676PMC
October 2010

E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease.

Blood 2009 Nov 4;114(19):4197-208. Epub 2009 Sep 4.

Department of Medicine, Hematology and Oncology and the Interdisciplinary Center for Clinical Research, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1182/blood-2008-12-190934DOI Listing
November 2009

Flt3-dependent transformation by inactivating c-Cbl mutations in AML.

Blood 2007 08 19;110(3):1004-12. Epub 2007 Apr 19.

Department of Medicine, Hematology and Oncology, and Interdisciplinary Center for Clinical Research, University Hospital Münster, Albert-Schweitzer-Strasse 33, 48129 Münster, Germany.

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http://dx.doi.org/10.1182/blood-2007-01-066076DOI Listing
August 2007

Activation mechanisms of STAT5 by oncogenic Flt3-ITD.

Blood 2007 Jul 13;110(1):370-4. Epub 2007 Mar 13.

Department of Medicine, Interdisciplinary Center for Clinical Research, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1182/blood-2006-05-024018DOI Listing
July 2007

Oncogenic signaling in acute myeloid leukemia.

Curr Drug Targets 2007 Feb;8(2):237-46

Dept. of Medicine, Hematology/Oncology, University of Münster, Albert-Schweitzer-Strasse 33, D-48149 Münster, Germany.

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http://dx.doi.org/10.2174/138945007779940197DOI Listing
February 2007

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

Blood 2005 Jul 15;106(1):265-73. Epub 2005 Mar 15.

Department of Medicine, Hematology/Oncology and Interdisciplinary Center for Clinical Research, University Münster, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-07-29
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http://dx.doi.org/10.1182/blood-2004-07-2942DOI Listing
July 2005

Flt3 tandem duplication mutations cooperate with Wnt signaling in leukemic signal transduction.

Blood 2005 May 13;105(9):3699-706. Epub 2005 Jan 13.

Department of Medicine, Hematology, and Oncology, University of Münster, Domagkstr. 3, 48149 Münster, Germany.

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http://dx.doi.org/10.1182/blood-2004-07-2924DOI Listing
May 2005

RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.

Blood 2005 Mar 9;105(5):2107-14. Epub 2004 Nov 9.

Department of Medicine, Hematology, and Oncology, and the Interdisciplinary Clinical Research Center (IZKF), University Hospital Münster, Albert-Schweitzer-Strasse 33, 48129 Münster, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-03-09
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http://dx.doi.org/10.1182/blood-2004-03-0940DOI Listing
March 2005

Phosphorylation-independent stabilization of p27kip1 by the phosphoinositide 3-kinase pathway in glioblastoma cells.

J Biol Chem 2005 Jan 12;280(3):2012-9. Epub 2004 Nov 12.

Cancer Research Institute, University of California, San Francisco, California 94115-0128, USA.

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http://dx.doi.org/10.1074/jbc.M408348200DOI Listing
January 2005

Oncolytic viruses for the treatment of cancer: current strategies and clinical trials.

Drug Discov Today 2004 Sep;9(17):759-68

University of Müster, Department of Medicine, Hematology and Oncology, Albert-Schweitzer-Strasse 33, D-48129 Münster, Germany.

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http://dx.doi.org/10.1016/S1359-6446(04)03221-0DOI Listing
September 2004

Replication-selective viruses for cancer therapy.

J Mol Med (Berl) 2002 Mar 20;80(3):163-75. Epub 2001 Dec 20.

SWITCH Biotech AG, Fraunhofer Strasse 10, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1007/s00109-001-0295-1DOI Listing
March 2002