Publications by authors named "Christian Beerli"

25Publications

Neutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controls.

Int J Chron Obstruct Pulmon Dis 2016;11:2139-2147. Epub 2016 Sep 6.

Respiratory Diseases, Novartis Institute for Biomedical Research, Horsham, West Sussex, UK.

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http://dx.doi.org/10.2147/COPD.S95578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019168PMC
September 2016

Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo.

Circ Res 2015 Jul 30;117(4):376-87. Epub 2015 Jun 30.

From the Medizinische Klinik und Poliklinik I, Klinikum der Universität München (N.U., F.G., M.-L.v.B., S.C., F.R., M.O., V.B., J.B., I.S., M.L., K.R.L., S.M.), Department of Applied Physics, Center for NanoSciences (K.R.L.), and Walther-Straub-Institute of Pharmacology and Toxicology (M.M.y.S.), Ludwig-Maximilians-Universität, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany (N.U., F.G., M.-L.v.B., S.C., F.R., M.O., J.B., I.S., M.L., M.M.y.S., S.M.); Heart Failure Institute, Research Center for Translational Medicine and Department of Cardiovascular Medicine, East Hospital, Tongji University School of Medicine, Shanghai, China (L.Z.); Institute of Pharmacology, University of Bern, Bern, Switzerland (A.H.); Pharmazentrum Frankfurt/ZAFES, Goethe University Hospital, Frankfurt am Main, Germany (J.M.P.); and Preclinical Safety (D.L., E.P.), and Autoimmunity, Transplantation and Inflammation (C.B., A.B., T.B.), Novartis Institutes for BioMedical Research, Basel, Switzerland.

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306901DOI Listing
July 2015

Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.

J Control Release 2013 Dec 15;172(3):975-82. Epub 2013 Oct 15.

Novartis Pharma AG, Biologics Process Research & Development, 4002 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.jconrel.2013.10.010DOI Listing
December 2013

Assay to measure the secretion of sphingosine-1-phosphate from cells induced by S1P lyase inhibitors.

Biochem Biophys Res Commun 2013 Apr 14;433(3):345-8. Epub 2013 Mar 14.

Novartis Institutes for BioMedical Research, Basel, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X130039
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http://dx.doi.org/10.1016/j.bbrc.2013.03.004DOI Listing
April 2013

Cellular assay for the characterization of sphingosine-1-phosphate lyase inhibitors.

Anal Biochem 2013 Mar 13;434(2):247-53. Epub 2012 Dec 13.

Novartis Institutes for BioMedical Research, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1016/j.ab.2012.11.026DOI Listing
March 2013

BZM055, an iodinated radiotracer candidate for PET and SPECT imaging of myelin and FTY720 brain distribution.

ChemMedChem 2011 Apr 30;6(4):667-77. Epub 2011 Jan 30.

Novartis Institutes for BioMedical Research, Basel, Global Discovery Chemistry, Neurosciences and Molecular Imaging, Postfach, 4002 Basel, Switzerland.

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http://dx.doi.org/10.1002/cmdc.201000477DOI Listing
April 2011

Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitro and in vivo.

J Med Chem 2008 Dec;51(24):7915-20

Novartis Institutes for BioMedical Research, Forum 1, Novartis Campus, CH-4002 Basel, Switzerland.

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http://dx.doi.org/10.1021/jm801065qDOI Listing
December 2008