Christian Barro

Christian Barro

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Christian Barro

Christian Barro

Publications by authors named "Christian Barro"

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Correlations between serum and CSF pNfH levels in ALS, FTD and controls: a comparison of three analytical approaches.

Clin Chem Lab Med 2019 Sep;57(10):1556-1564

Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1515/cclm-2019-0015DOI Listing
September 2019

Serum neurofilament light chain in pediatric MS and other acquired demyelinating syndromes.

Neurology 2019 Sep 5;93(10):e968-e974. Epub 2019 Aug 5.

From the Department of Neurology, MS Centre ErasMS (Y.Y.M.W., A.L.B., D.v.P., R.Q.H.), Department of Immunology (M.-J.M., A.F.W., R.Q.H.), and Department of Pediatric Neurology (R.F.N.), Erasmus MC, Rotterdam, the Netherlands; and Neurologic Clinic and Policlinic (C.B., Z.M., J.K.), University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000008057DOI Listing
September 2019

Serum Neurofilament Light Chain Levels in Patients With Presymptomatic Multiple Sclerosis.

JAMA Neurol 2019 Sep 13. Epub 2019 Sep 13.

Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jamaneurol.2019.3238DOI Listing
September 2019

Serum neurofilament light chain levels associations with gray matter pathology: a 5-year longitudinal study.

Ann Clin Transl Neurol 2019 Aug 22. Epub 2019 Aug 22.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.

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http://dx.doi.org/10.1002/acn3.50872DOI Listing
August 2019

Serum GFAP and neurofilament light as biomarkers of disease activity and disability in NMOSD.

Neurology 2019 Aug 30. Epub 2019 Aug 30.

From the Departments of Neurology (M.W., Y.N., T.M., F.H., R.Y., J.-i.K.) and Neurological Therapeutics (N.I.), Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; and Neurology (Z.M., C.B., D.L., J.K.), Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000008160DOI Listing
August 2019

Serum neurofilament light chain as a prognostic marker in postanoxic encephalopathy.

Epilepsy Behav 2019 Jul 30:106432. Epub 2019 Jul 30.

Neurocenter of Southern Switzerland, Civic Hospital, Lugano, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2019.07.033DOI Listing
July 2019

Serum neurofilament light chain in chronic inflammatory demyelinating polyneuropathy.

J Peripher Nerv Syst 2019 Jun 29;24(2):187-194. Epub 2019 Apr 29.

Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam Neuroscience, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/jns.12319DOI Listing
June 2019

Blood neurofilament light as a potential endpoint in Phase 2 studies in MS.

Ann Clin Transl Neurol 2019 Jun 28;6(6):1081-1089. Epub 2019 May 28.

Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, Biomedicine and Biomedical Engineering University Hospital Basel, University of Basel Basel Switzerland.

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http://dx.doi.org/10.1002/acn3.795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562031PMC
June 2019

Serum neurofilament light chain is a biomarker of acute and chronic neuronal damage in early multiple sclerosis.

Mult Scler 2019 Apr 15;25(5):678-686. Epub 2018 Mar 15.

Department of Neurology and Focus Program Translational Neuroscience (FTN), Research Center for Immunotherapy (FZI), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.1177/1352458518765666DOI Listing
April 2019

Blood neurofilament light chain as a biomarker of MS disease activity and treatment response.

Neurology 2019 Mar 8;92(10):e1007-e1015. Epub 2019 Feb 8.

From the Neurologic Clinic and Policlinic (J.K., C.B., L.K.), Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel; Novartis Pharma AG (H.K., D.A.H., F.D., D.T., D.L.), Basel, Switzerland; Novartis Healthcare Pvt. Ltd. (U.K.), Hyderabad, India; and DATAMAP GmbH (R.M.), Freiburg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000007032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442011PMC
March 2019

Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity.

Mult Scler 2018 Dec 20:1352458518819380. Epub 2018 Dec 20.

Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland/Division of Clinical Neurosciences, Turku University Hospital and University of Turku, Turku, Finland.

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http://dx.doi.org/10.1177/1352458518819380DOI Listing
December 2018

Neurofilament Light Chain: Blood Biomarker of Neonatal Neuronal Injury.

Front Neurol 2018 20;9:984. Epub 2018 Nov 20.

Department of Neonatology, University Children's Hospital Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.3389/fneur.2018.00984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256184PMC
November 2018

Neurofilaments as biomarkers in neurological disorders.

Nat Rev Neurol 2018 10;14(10):577-589

Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, and Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland.

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http://www.nature.com/articles/s41582-018-0058-z
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http://dx.doi.org/10.1038/s41582-018-0058-zDOI Listing
October 2018

Serum neurofilament light: A biomarker of neuroaxonal injury after ischemic stroke.

Neurology 2018 10 14;91(14):e1338-e1347. Epub 2018 Sep 14.

From the Institute for Stroke and Dementia Research, University Hospital (S.T., M. Duering, A.G.K., J.B., B.G., F.A.W., M. Dichgans), and Graduate School of Systemic Neurosciences (S.T.), LMU Munich; Munich Cluster for Systems Neurology (SyNergy) (S.T., M. Dichgans), Munich, Germany; Neurologic Clinic and Policlinic (C.B., J.K.), Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Switzerland; German Center for Neurodegenerative Diseases (DZNE) (F.J.B., G.C.P.), Bonn; Department of Neurology (F.J.B., G.C.P.), University Hospital Bonn; Departments of Neurology (M.K., L.K.), Neuroradiology (F.D.), and Radiology (B.E.-W.), University Hospital, LMU Munich; Department of Neurology (M.W.G.), University of Magdeburg, University Hospital; German Center for Neurodegenerative Diseases (DZNE) (M.W.G.), Magdeburg, Germany; Stroke Center and Department of Neurology (N.P.), University Hospital Basel, Switzerland; and German Center for Neurodegenerative Diseases (DZNE) (M. Dichgans), Munich, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006282DOI Listing
October 2018

NfL is a biomarker for adult-onset leukoencephalopathy with axonal spheroids and pigmented glia.

Neurology 2018 10 14;91(16):755-757. Epub 2018 Sep 14.

From the Department of Neurodegenerative Diseases (S.N.H., L.S.), Hertie-Institute for Clinical Brain Research & Center of Neurology, University of Tübingen, Germany; German Research Center for Neurodegenerative Diseases (DZNE) (S.N.H., L.S.), Tübingen, Germany; Institute of Human Genetics (I.K., F.R., J.R.L.), University of Leipzig, Germany; Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research (C.B., J.K.), University Hospital Basel, University of Basel, Switzerland; and Department of Neurology (P.K.), University of Magdeburg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006357DOI Listing
October 2018

Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis.

Brain 2018 08;141(8):2382-2391

Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1093/brain/awy154DOI Listing
August 2018

Serum neurofilament light chain: a biomarker of neuronal injury in vasculitic neuropathy.

Ann Rheum Dis 2018 07 25;77(7):1093-1094. Epub 2017 Jul 25.

Clinic for Rheumatology, Department of Medicine, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1136/annrheumdis-2017-212045DOI Listing
July 2018

Neurofilament light chain predicts disease activity in relapsing-remitting MS.

Neurol Neuroimmunol Neuroinflamm 2018 Jan 28;5(1):e422. Epub 2017 Nov 28.

Department of Neurology (K.N.V., K.B., K.-M.M., Ø.T., S.W., L.A.B., C.V.), Haukeland University Hospital; Department of Clinical Medicine (K.N.V., K.-M.M., Ø.T., S.W., L.A.B., C.V.), University of Bergen, Norway; Neurologic Clinic and Policlinic (C.B., J.K.), Departments of Medicine, Clinical Research and Biomedicine, University Hospital Basel, University of Basel, Switzerland; Department of Global Public Health and Primary Care (K.B.), University of Bergen, Norway; and Norwegian MS-Registry & Biobank (K.-M.M.).

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http://dx.doi.org/10.1212/NXI.0000000000000422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707445PMC
January 2018

Multicenter evaluation of neurofilaments in early symptom onset amyotrophic lateral sclerosis.

Neurology 2018 01 6;90(1):e22-e30. Epub 2017 Dec 6.

From the Nuffield Department of Clinical Neurosciences (E.F., E.G., M.R.T.), University of Oxford, UK; Department of Neurology (P.O., P.S., F.V., J.H.W., P.W., A.C.L., M.O.), Ulm University Hospital, Germany; Department of Pathophysiology and Transplantation (F.V., V.S.), Università degli Studi di Milano; Department of Neurology-Stroke Unit and Laboratory of Neuroscience (F.V., C.M., V.S.), IRCCS Istituto Auxologico Italiano, Milan, Italy; Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, and Biomedicine (C.B., J.K.), University Hospital and University of Basel, Switzerland; Department of Neurology (P.V.D.) and Laboratory of Molecular Neurobiomarker Research and Laboratory Medicine (K.P.), University Hospitals Leuven; KU Leuven-University of Leuven (P.V.D.); Department of Neurosciences (P.V.D.), VIB-Center for Brain & Disease Research, Leuven, Belgium; Department of Neurology (J.G., P.M., B.S.), Jena University Hospital, Germany; Department of Metabolic Biochemistry (C.J., F.L.) and Neurological Diseases Department (M.d.M.A., F.S.), Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris, France; Department of Neurology (S.K., S.P.), Hannover Medical School; Institute for Epidemiology and Medical Biometry (B.M.) Ulm University, Germany; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology (J.R., M.M.V.), and Radboud Alzheimer Center, Department of Laboratory Medicine (M.M.V.), Radboud University Medical Center, Nijmegen, the Netherlands; and Department of Neurodegenerative Disease and Gerontopsychiatry/Neurology (P.W.), Bonn University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004761DOI Listing
January 2018

Serum neurofilament light is sensitive to active cerebral small vessel disease.

Neurology 2017 Nov 18;89(20):2108-2114. Epub 2017 Oct 18.

From the Department of Neurology (T.G., D.P., C.E., T.S.-H., M.K., S.F., A.P., M.V., L.P., E.H., S.R., R.S., F.F., M.K.), Division of Neuroradiology, Vascular and Interventional Radiology (C.E.), and Institute for Medical Informatics, Statistics and Documentation (E.H.), Medical University of Graz, Austria; and Neurologic Clinic and Policlinic (C.B., S.G., J,K.), Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, University of Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000004645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711505PMC
November 2017

Fluid biomarker and electrophysiological outcome measures for progressive MS trials.

Mult Scler 2017 Oct;23(12):1600-1613

Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine and Clinical Research, University Hospital of Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1177/1352458517732844DOI Listing
October 2017

Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis.

Ann Neurol 2017 Jun;81(6):857-870

Neurologic Clinic and Policlinic, Departments of Medicine, Biomedicine, and Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1002/ana.24954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519945PMC
June 2017

Serum neurofilament is associated with progression of brain atrophy and disability in early MS.

Neurology 2017 Feb 1;88(9):826-831. Epub 2017 Feb 1.

From Neurologic Clinic and Policlinic (J.K., C.B., O.Y.), Departments of Medicine, Clinical Research, and Biomedicine, University Hospital Basel, University of Basel, Switzerland; Department of Neurology (B.N., E.W.), University of California San Francisco; Department of Neuroimmunology (D.G.), Queen Square, Institute of Neurology, London; independent statistician (S.M.), Haddenham, Bucks, UK; Department of Neurology (D.P.), University of Southern California, Los Angeles; and Department of Neuroscience and Trauma (G.G., S.G.), Queen Mary University of London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000003653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331872PMC
February 2017

Neurofilament light chain in FTD is elevated not only in cerebrospinal fluid, but also in serum.

J Neurol Neurosurg Psychiatry 2016 11 17;87(11):1270-1272. Epub 2016 May 17.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany German Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1136/jnnp-2015-312972DOI Listing
November 2016

Serum neurofilament light chain in early relapsing remitting MS is increased and correlates with CSF levels and with MRI measures of disease severity.

Mult Scler 2016 10 11;22(12):1550-1559. Epub 2016 Jan 11.

Advanced Clinical Imaging Technology Group, Siemens Healthcare IM BM PI, Lausanne, Switzerland/Neuro-Immunology, Neurology Division, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland/LTS5, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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http://dx.doi.org/10.1177/1352458515623365DOI Listing
October 2016

Neurofilament Light Chain Determination from Peripheral Blood Samples.

Methods Mol Biol 2016 ;1304:93-8

Neurology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.

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http://link.springer.com/content/pdf/10.1007/7651_2015_206.p
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http://link.springer.com/10.1007/7651_2015_206
Publisher Site
http://dx.doi.org/10.1007/7651_2015_206DOI Listing
May 2016