Chris Wallace

Chris Wallace

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Chris Wallace

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Recent Trends in Neurosurgery Career Outcomes in Canada.

Can J Neurol Sci 2019 Jul 23;46(4):436-442. Epub 2019 Apr 23.

Division of Neurosurgery,University of British Columbia,Victoria, BC,Canada.

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http://dx.doi.org/10.1017/cjn.2019.22DOI Listing
July 2019

Stochastic search and joint fine-mapping increases accuracy and identifies previously unreported associations in immune-mediated diseases.

Nat Commun 2019 Jul 19;10(1):3216. Epub 2019 Jul 19.

MRC Biostatistics Unit, University of Cambridge, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK.

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http://dx.doi.org/10.1038/s41467-019-11271-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642100PMC
July 2019

simGWAS: a fast method for simulation of large scale case-control GWAS summary statistics.

Bioinformatics 2019 Jun;35(11):1901-1906

MRC Biostatistics Unit, Cambridge Institute of Public Health, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/bty898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546134PMC
June 2019

Fine mapping chromatin contacts in capture Hi-C data.

BMC Genomics 2019 Jan 23;20(1):77. Epub 2019 Jan 23.

Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

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http://dx.doi.org/10.1186/s12864-018-5314-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343296PMC
January 2019

Comparison of mobility and user satisfaction between a microprocessor knee and a standard prosthetic knee: a summary of seven single-subject trials.

Int J Rehabil Res 2018 Mar;41(1):63-73

Center for Neuroscience and Neurological Recovery, Methodist Rehabilitation Center, Jackson, Mississippi, USA.

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http://Insights.ovid.com/crossref?an=00004356-201803000-0001
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http://dx.doi.org/10.1097/MRR.0000000000000267DOI Listing
March 2018

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

Diabetologia 2018 Jan 5;61(1):147-157. Epub 2017 Oct 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, NIHR Oxford Biomedical Research Centre, Nuffield Department of Medicine, Roosevelt Drive, Oxford, OX3 7BN, UK.

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http://dx.doi.org/10.1007/s00125-017-4440-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719131PMC
January 2018

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.

J Autoimmun 2017 Nov 23;84:75-86. Epub 2017 Jul 23.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust/MRC Building, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656572PMC
November 2017

Increased alertness, better than posture prioritization, explains dual-task performance in prosthesis users and controls under increasing postural and cognitive challenge.

Exp Brain Res 2017 11 31;235(11):3527-3539. Epub 2017 Aug 31.

Center for Neuroscience and Neurological Recovery, Methodist Rehabilitation Center, Jackson, USA.

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http://dx.doi.org/10.1007/s00221-017-5077-2DOI Listing
November 2017

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

JCI Insight 2017 Aug 17;2(16). Epub 2017 Aug 17.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1172/jci.insight.93739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621870PMC
August 2017

A method for identifying genetic heterogeneity within phenotypically defined disease subgroups.

Nat Genet 2017 Feb 26;49(2):310-316. Epub 2016 Dec 26.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357574PMC
February 2017

Residual standard deviation: Validation of a new measure of dual-task cost in below-knee prosthesis users.

Gait Posture 2017 01 26;51:91-96. Epub 2016 Sep 26.

Center for Neuroscience and Neurological Recovery, Methodist Rehabilitation Center, Jackson, MS, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S09666362163058
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http://dx.doi.org/10.1016/j.gaitpost.2016.09.025DOI Listing
January 2017

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

Diabetes 2015 Nov 29;64(11):3891-902. Epub 2015 Jul 29.

Department of Immunobiology, Faculty of Life Sciences & Medicine, King's College London, London, U.K. National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' National Health Service Foundation Trust and King's College London, London, U.K.

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http://dx.doi.org/10.2337/db15-0516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975524PMC
November 2015

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

Eur J Immunol 2015 Nov 1;45(11):3200-3. Epub 2015 Oct 1.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.201545646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832369PMC
November 2015

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci.

Nat Commun 2015 Nov 30;6:10069. Epub 2015 Nov 30.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Faculty of Medical and Human Sciences, Manchester Academic Health Science Centre, The University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1038/ncomms10069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674669PMC
November 2015

Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.

Nat Genet 2015 Jul 8;47(7):839-46. Epub 2015 Jun 8.

1] JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. [2] Medical Research Council Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754941PMC
July 2015

Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases.

Hum Mol Genet 2015 Jun 5;24(12):3305-13. Epub 2015 Mar 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK, MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge CB2 0SR, UK

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http://dx.doi.org/10.1093/hmg/ddv077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498151PMC
June 2015

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

PLoS Genet 2015 Jun 24;11(6):e1005272. Epub 2015 Jun 24.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1005272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481316PMC
June 2015

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

Nat Commun 2015 May 12;6:7000. Epub 2015 May 12.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1038/ncomms8000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432600PMC
May 2015

IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Diabetologia 2015 Apr 6;58(4):781-90. Epub 2015 Feb 6.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, WT/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK,

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http://dx.doi.org/10.1007/s00125-015-3509-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351433PMC
April 2015

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.

Nat Commun 2015 Feb 5;6:6046. Epub 2015 Feb 5.

1] Arthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester M13 9PT, UK [2] NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academy of Health Sciences, Manchester M13 9WU, UK.

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http://dx.doi.org/10.1038/ncomms7046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327416PMC
February 2015

A pleiotropy-informed Bayesian false discovery rate adapted to a shared control design finds new disease associations from GWAS summary statistics.

PLoS Genet 2015 Feb 6;11(2):e1004926. Epub 2015 Feb 6.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom; MRC Biostatistics Unit, Institute of Public Health, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450050PMC
February 2015

VSEAMS: a pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes.

Bioinformatics 2014 Dec 27;30(23):3342-8. Epub 2014 Aug 27.

Department of Medical Genetics, JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK and MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK Department of Medical Genetics, JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK and MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge, CB2 0SR, UK.

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http://dx.doi.org/10.1093/bioinformatics/btu571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296156PMC
December 2014

A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.

Genet Epidemiol 2014 Dec 4;38(8):661-70. Epub 2014 Nov 4.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.1002/gepi.21853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258092PMC
December 2014

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

BMC Genomics 2014 Apr 11;15:274. Epub 2014 Apr 11.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, CB2 0XY, Cambridge, UK.

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http://dx.doi.org/10.1186/1471-2164-15-274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029094PMC
April 2014

Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients.

Diabetologia 2014 Feb 22;57(2):366-72. Epub 2013 Nov 22.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0XY, UK.

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http://link.springer.com/10.1007/s00125-013-3113-8
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http://dx.doi.org/10.1007/s00125-013-3113-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890035PMC
February 2014

Statistical testing of shared genetic control for potentially related traits.

Authors:
Chris Wallace

Genet Epidemiol 2013 Dec 5;37(8):802-13. Epub 2013 Nov 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

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http://doi.wiley.com/10.1002/gepi.21765
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http://dx.doi.org/10.1002/gepi.21765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158901PMC
December 2013

Stride length-cadence relationship is disrupted in below-knee prosthesis users.

Gait Posture 2013 Sep 14;38(4):883-7. Epub 2013 May 14.

Division of Orthotics and Prosthetics, Methodist Rehabilitation Center, Jackson, MS, United States; Center for Neuroscience and Neurological Recovery, Methodist Rehabilitation Center, Jackson, MS, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09666362130019
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http://dx.doi.org/10.1016/j.gaitpost.2013.04.008DOI Listing
September 2013

Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors.

J Immunol 2013 Mar 15;190(6):2554-66. Epub 2013 Feb 15.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1202914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614027PMC
March 2013

Seven newly identified loci for autoimmune thyroid disease.

Hum Mol Genet 2012 Dec 24;21(23):5202-8. Epub 2012 Aug 24.

Department of Medical Genetics, Cambridge Institute for Medical Research, Juvenile Diabetes Research Foundation/ Wellcome Trust Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/dds357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490518PMC
December 2012

Extra-binomial variation approach for analysis of pooled DNA sequencing data.

Bioinformatics 2012 Nov 12;28(22):2898-904. Epub 2012 Sep 12.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Cambridge CB2 0XY, UK.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/bts553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496343PMC
November 2012

Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes.

Hum Mol Genet 2012 Jun 8;21(12):2815-24. Epub 2012 Mar 8.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/dds098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363338PMC
June 2012

Lower limb preference on goal-oriented tasks in unilateral prosthesis users.

Gait Posture 2012 Jun 29;36(2):249-53. Epub 2012 Mar 29.

Division of Orthotics and Prosthetics, Methodist Rehabilitation Center, Jackson, MS 39216, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09666362120007
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http://dx.doi.org/10.1016/j.gaitpost.2012.03.001DOI Listing
June 2012

Blood pressure loci identified with a gene-centric array.

Authors:
Toby Johnson Tom R Gaunt Stephen J Newhouse Sandosh Padmanabhan Maciej Tomaszewski Meena Kumari Richard W Morris Ioanna Tzoulaki Eoin T O'Brien Neil R Poulter Peter Sever Denis C Shields Simon Thom Sasiwarang G Wannamethee Peter H Whincup Morris J Brown John M Connell Richard J Dobson Philip J Howard Charles A Mein Abiodun Onipinla Sue Shaw-Hawkins Yun Zhang George Davey Smith Ian N M Day Debbie A Lawlor Alison H Goodall F Gerald Fowkes Gonçalo R Abecasis Paul Elliott Vesela Gateva Peter S Braund Paul R Burton Christopher P Nelson Martin D Tobin Pim van der Harst Nicola Glorioso Hani Neuvrith Erika Salvi Jan A Staessen Andrea Stucchi Nabila Devos Xavier Jeunemaitre Pierre-François Plouin Jean Tichet Peeter Juhanson Elin Org Margus Putku Siim Sõber Gudrun Veldre Margus Viigimaa Anna Levinsson Annika Rosengren Dag S Thelle Claire E Hastie Thomas Hedner Wai K Lee Olle Melander Björn Wahlstrand Rebecca Hardy Andrew Wong Jackie A Cooper Jutta Palmen Li Chen Alexandre F R Stewart George A Wells Harm-Jan Westra Marcel G M Wolfs Robert Clarke Maria Grazia Franzosi Anuj Goel Anders Hamsten Mark Lathrop John F Peden Udo Seedorf Hugh Watkins Willem H Ouwehand Jennifer Sambrook Jonathan Stephens Juan-Pablo Casas Fotios Drenos Michael V Holmes Mika Kivimaki Sonia Shah Tina Shah Philippa J Talmud John Whittaker Chris Wallace Christian Delles Maris Laan Diana Kuh Steve E Humphries Fredrik Nyberg Daniele Cusi Robert Roberts Christopher Newton-Cheh Lude Franke Alice V Stanton Anna F Dominiczak Martin Farrall Aroon D Hingorani Nilesh J Samani Mark J Caulfield Patricia B Munroe

Am J Hum Genet 2011 Dec 17;89(6):688-700. Epub 2011 Nov 17.

Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.

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http://dx.doi.org/10.1016/j.ajhg.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234370PMC
December 2011

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes.

Diabetes Metab Res Rev 2011 Nov;27(8):838-43

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1002/dmrr.1259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816329PMC
November 2011

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Authors:
John C Chambers Weihua Zhang Joban Sehmi Xinzhong Li Mark N Wass Pim Van der Harst Hilma Holm Serena Sanna Maryam Kavousi Sebastian E Baumeister Lachlan J Coin Guohong Deng Christian Gieger Nancy L Heard-Costa Jouke-Jan Hottenga Brigitte Kühnel Vinod Kumar Vasiliki Lagou Liming Liang Jian'an Luan Pedro Marques Vidal Irene Mateo Leach Paul F O'Reilly John F Peden Nilufer Rahmioglu Pasi Soininen Elizabeth K Speliotes Xin Yuan Gudmar Thorleifsson Behrooz Z Alizadeh Larry D Atwood Ingrid B Borecki Morris J Brown Pimphen Charoen Francesco Cucca Debashish Das Eco J C de Geus Anna L Dixon Angela Döring Georg Ehret Gudmundur I Eyjolfsson Martin Farrall Nita G Forouhi Nele Friedrich Wolfram Goessling Daniel F Gudbjartsson Tamara B Harris Anna-Liisa Hartikainen Simon Heath Gideon M Hirschfield Albert Hofman Georg Homuth Elina Hyppönen Harry L A Janssen Toby Johnson Antti J Kangas Ido P Kema Jens P Kühn Sandra Lai Mark Lathrop Markus M Lerch Yun Li T Jake Liang Jing-Ping Lin Ruth J F Loos Nicholas G Martin Miriam F Moffatt Grant W Montgomery Patricia B Munroe Kiran Musunuru Yusuke Nakamura Christopher J O'Donnell Isleifur Olafsson Brenda W Penninx Anneli Pouta Bram P Prins Inga Prokopenko Ralf Puls Aimo Ruokonen Markku J Savolainen David Schlessinger Jeoffrey N L Schouten Udo Seedorf Srijita Sen-Chowdhry Katherine A Siminovitch Johannes H Smit Timothy D Spector Wenting Tan Tanya M Teslovich Taru Tukiainen Andre G Uitterlinden Melanie M Van der Klauw Ramachandran S Vasan Chris Wallace Henri Wallaschofski H-Erich Wichmann Gonneke Willemsen Peter Würtz Chun Xu Laura M Yerges-Armstrong Goncalo R Abecasis Kourosh R Ahmadi Dorret I Boomsma Mark Caulfield William O Cookson Cornelia M van Duijn Philippe Froguel Koichi Matsuda Mark I McCarthy Christa Meisinger Vincent Mooser Kirsi H Pietiläinen Gunter Schumann Harold Snieder Michael J E Sternberg Ronald P Stolk Howard C Thomas Unnur Thorsteinsdottir Manuela Uda Gérard Waeber Nicholas J Wareham Dawn M Waterworth Hugh Watkins John B Whitfield Jacqueline C M Witteman Bruce H R Wolffenbuttel Caroline S Fox Mika Ala-Korpela Kari Stefansson Peter Vollenweider Henry Völzke Eric E Schadt James Scott Marjo-Riitta Järvelin Paul Elliott Jaspal S Kooner

Nat Genet 2011 Oct 16;43(11):1131-8. Epub 2011 Oct 16.

Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, UK.

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http://hmg.oxfordjournals.org/content/early/2012/09/04/hmg.d
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http://www.nature.com/doifinder/10.1038/ng.970
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http://dx.doi.org/10.1038/ng.970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482372PMC
October 2011

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

PLoS Genet 2011 Aug 4;7(8):e1002216. Epub 2011 Aug 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150451PMC
August 2011

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.

Diabetes 2011 May 25;60(5):1624-31. Epub 2011 Mar 25.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.2337/db10-1656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292339PMC
May 2011

An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes.

Diabetes 2011 Mar 26;60(3):1041-4. Epub 2011 Jan 26.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db10
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http://dx.doi.org/10.2337/db10-0446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046822PMC
March 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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January 2011

Reduced expression of IFIH1 is protective for type 1 diabetes.

PLoS One 2010 Sep 9;5(9). Epub 2010 Sep 9.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012646PLOS
September 2010

Genetic loci influencing kidney function and chronic kidney disease.

Authors:
John C Chambers Weihua Zhang Graham M Lord Pim van der Harst Debbie A Lawlor Joban S Sehmi Daniel P Gale Mark N Wass Kourosh R Ahmadi Stephan J L Bakker Jacqui Beckmann Henk J G Bilo Murielle Bochud Morris J Brown Mark J Caulfield John M C Connell H Terence Cook Ioana Cotlarciuc George Davey Smith Ranil de Silva Guohong Deng Olivier Devuyst Lambert D Dikkeschei Nada Dimkovic Mark Dockrell Anna Dominiczak Shah Ebrahim Thomas Eggermann Martin Farrall Luigi Ferrucci Jurgen Floege Nita G Forouhi Ron T Gansevoort Xijin Han Bo Hedblad Jaap J Homan van der Heide Bouke G Hepkema Maria Hernandez-Fuentes Elina Hypponen Toby Johnson Paul E de Jong Nanne Kleefstra Vasiliki Lagou Marta Lapsley Yun Li Ruth J F Loos Jian'an Luan Karin Luttropp Céline Maréchal Olle Melander Patricia B Munroe Louise Nordfors Afshin Parsa Leena Peltonen Brenda W Penninx Esperanza Perucha Anneli Pouta Inga Prokopenko Paul J Roderick Aimo Ruokonen Nilesh J Samani Serena Sanna Martin Schalling David Schlessinger Georg Schlieper Marc A J Seelen Alan R Shuldiner Marketa Sjögren Johannes H Smit Harold Snieder Nicole Soranzo Timothy D Spector Peter Stenvinkel Michael J E Sternberg Ramasamyiyer Swaminathan Toshiko Tanaka Lielith J Ubink-Veltmaat Manuela Uda Peter Vollenweider Chris Wallace Dawn Waterworth Klaus Zerres Gerard Waeber Nicholas J Wareham Patrick H Maxwell Mark I McCarthy Marjo-Riitta Jarvelin Vincent Mooser Goncalo R Abecasis Liz Lightstone James Scott Gerjan Navis Paul Elliott Jaspal S Kooner

Nat Genet 2010 May 11;42(5):373-5. Epub 2010 Apr 11.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College of London, London, UK.

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http://dx.doi.org/10.1038/ng.566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748585PMC
May 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Two small flaps from one anterolateral thigh donor site for bilateral buccal mucosa reconstruction after release of submucous fibrosis and/or contracture.

J Plast Reconstr Aesthet Surg 2010 Mar 9;63(3):440-5. Epub 2009 Apr 9.

Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, Linkou, Taiwan.

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March 2010

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.

Nat Genet 2010 Jan 6;42(1):68-71. Epub 2009 Dec 6.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820243PMC
January 2010

Genome-wide association study identifies eight loci associated with blood pressure.

Authors:
Christopher Newton-Cheh Toby Johnson Vesela Gateva Martin D Tobin Murielle Bochud Lachlan Coin Samer S Najjar Jing Hua Zhao Simon C Heath Susana Eyheramendy Konstantinos Papadakis Benjamin F Voight Laura J Scott Feng Zhang Martin Farrall Toshiko Tanaka Chris Wallace John C Chambers Kay-Tee Khaw Peter Nilsson Pim van der Harst Silvia Polidoro Diederick E Grobbee N Charlotte Onland-Moret Michiel L Bots Louise V Wain Katherine S Elliott Alexander Teumer Jian'an Luan Gavin Lucas Johanna Kuusisto Paul R Burton David Hadley Wendy L McArdle Morris Brown Anna Dominiczak Stephen J Newhouse Nilesh J Samani John Webster Eleftheria Zeggini Jacques S Beckmann Sven Bergmann Noha Lim Kijoung Song Peter Vollenweider Gerard Waeber Dawn M Waterworth Xin Yuan Leif Groop Marju Orho-Melander Alessandra Allione Alessandra Di Gregorio Simonetta Guarrera Salvatore Panico Fulvio Ricceri Valeria Romanazzi Carlotta Sacerdote Paolo Vineis Inês Barroso Manjinder S Sandhu Robert N Luben Gabriel J Crawford Pekka Jousilahti Markus Perola Michael Boehnke Lori L Bonnycastle Francis S Collins Anne U Jackson Karen L Mohlke Heather M Stringham Timo T Valle Cristen J Willer Richard N Bergman Mario A Morken Angela Döring Christian Gieger Thomas Illig Thomas Meitinger Elin Org Arne Pfeufer H Erich Wichmann Sekar Kathiresan Jaume Marrugat Christopher J O'Donnell Stephen M Schwartz David S Siscovick Isaac Subirana Nelson B Freimer Anna-Liisa Hartikainen Mark I McCarthy Paul F O'Reilly Leena Peltonen Anneli Pouta Paul E de Jong Harold Snieder Wiek H van Gilst Robert Clarke Anuj Goel Anders Hamsten John F Peden Udo Seedorf Ann-Christine Syvänen Giovanni Tognoni Edward G Lakatta Serena Sanna Paul Scheet David Schlessinger Angelo Scuteri Marcus Dörr Florian Ernst Stephan B Felix Georg Homuth Roberto Lorbeer Thorsten Reffelmann Rainer Rettig Uwe Völker Pilar Galan Ivo G Gut Serge Hercberg G Mark Lathrop Diana Zelenika Panos Deloukas Nicole Soranzo Frances M Williams Guangju Zhai Veikko Salomaa Markku Laakso Roberto Elosua Nita G Forouhi Henry Völzke Cuno S Uiterwaal Yvonne T van der Schouw Mattijs E Numans Giuseppe Matullo Gerjan Navis Göran Berglund Sheila A Bingham Jaspal S Kooner John M Connell Stefania Bandinelli Luigi Ferrucci Hugh Watkins Tim D Spector Jaakko Tuomilehto David Altshuler David P Strachan Maris Laan Pierre Meneton Nicholas J Wareham Manuela Uda Marjo-Riitta Jarvelin Vincent Mooser Olle Melander Ruth J F Loos Paul Elliott Gonçalo R Abecasis Mark Caulfield Patricia B Munroe

Nat Genet 2009 Jun 10;41(6):666-76. Epub 2009 May 10.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.

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June 2009

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

Authors:
Cecilia M Lindgren Iris M Heid Joshua C Randall Claudia Lamina Valgerdur Steinthorsdottir Lu Qi Elizabeth K Speliotes Gudmar Thorleifsson Cristen J Willer Blanca M Herrera Anne U Jackson Noha Lim Paul Scheet Nicole Soranzo Najaf Amin Yurii S Aulchenko John C Chambers Alexander Drong Jian'an Luan Helen N Lyon Fernando Rivadeneira Serena Sanna Nicholas J Timpson M Carola Zillikens Jing Hua Zhao Peter Almgren Stefania Bandinelli Amanda J Bennett Richard N Bergman Lori L Bonnycastle Suzannah J Bumpstead Stephen J Chanock Lynn Cherkas Peter Chines Lachlan Coin Cyrus Cooper Gabriel Crawford Angela Doering Anna Dominiczak Alex S F Doney Shah Ebrahim Paul Elliott Michael R Erdos Karol Estrada Luigi Ferrucci Guido Fischer Nita G Forouhi Christian Gieger Harald Grallert Christopher J Groves Scott Grundy Candace Guiducci David Hadley Anders Hamsten Aki S Havulinna Albert Hofman Rolf Holle John W Holloway Thomas Illig Bo Isomaa Leonie C Jacobs Karen Jameson Pekka Jousilahti Fredrik Karpe Johanna Kuusisto Jaana Laitinen G Mark Lathrop Debbie A Lawlor Massimo Mangino Wendy L McArdle Thomas Meitinger Mario A Morken Andrew P Morris Patricia Munroe Narisu Narisu Anna Nordström Peter Nordström Ben A Oostra Colin N A Palmer Felicity Payne John F Peden Inga Prokopenko Frida Renström Aimo Ruokonen Veikko Salomaa Manjinder S Sandhu Laura J Scott Angelo Scuteri Kaisa Silander Kijoung Song Xin Yuan Heather M Stringham Amy J Swift Tiinamaija Tuomi Manuela Uda Peter Vollenweider Gerard Waeber Chris Wallace G Bragi Walters Michael N Weedon Jacqueline C M Witteman Cuilin Zhang Weihua Zhang Mark J Caulfield Francis S Collins George Davey Smith Ian N M Day Paul W Franks Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Augustine Kong Jaspal S Kooner Markku Laakso Edward Lakatta Vincent Mooser Andrew D Morris Leena Peltonen Nilesh J Samani Timothy D Spector David P Strachan Toshiko Tanaka Jaakko Tuomilehto André G Uitterlinden Cornelia M van Duijn Nicholas J Wareham Hugh Watkins Dawn M Waterworth Michael Boehnke Panos Deloukas Leif Groop David J Hunter Unnur Thorsteinsdottir David Schlessinger H-Erich Wichmann Timothy M Frayling Gonçalo R Abecasis Joel N Hirschhorn Ruth J F Loos Kari Stefansson Karen L Mohlke Inês Barroso Mark I McCarthy

PLoS Genet 2009 Jun 26;5(6):e1000508. Epub 2009 Jun 26.

Wellcome Trust Centre for Human Genetics, University of Oxford, , Oxford, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695778PMC
June 2009

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Authors:
Cristen J Willer Elizabeth K Speliotes Ruth J F Loos Shengxu Li Cecilia M Lindgren Iris M Heid Sonja I Berndt Amanda L Elliott Anne U Jackson Claudia Lamina Guillaume Lettre Noha Lim Helen N Lyon Steven A McCarroll Konstantinos Papadakis Lu Qi Joshua C Randall Rosa Maria Roccasecca Serena Sanna Paul Scheet Michael N Weedon Eleanor Wheeler Jing Hua Zhao Leonie C Jacobs Inga Prokopenko Nicole Soranzo Toshiko Tanaka Nicholas J Timpson Peter Almgren Amanda Bennett Richard N Bergman Sheila A Bingham Lori L Bonnycastle Morris Brown Noël P Burtt Peter Chines Lachlan Coin Francis S Collins John M Connell Cyrus Cooper George Davey Smith Elaine M Dennison Parimal Deodhar Paul Elliott Michael R Erdos Karol Estrada David M Evans Lauren Gianniny Christian Gieger Christopher J Gillson Candace Guiducci Rachel Hackett David Hadley Alistair S Hall Aki S Havulinna Johannes Hebebrand Albert Hofman Bo Isomaa Kevin B Jacobs Toby Johnson Pekka Jousilahti Zorica Jovanovic Kay-Tee Khaw Peter Kraft Mikko Kuokkanen Johanna Kuusisto Jaana Laitinen Edward G Lakatta Jian'an Luan Robert N Luben Massimo Mangino Wendy L McArdle Thomas Meitinger Antonella Mulas Patricia B Munroe Narisu Narisu Andrew R Ness Kate Northstone Stephen O'Rahilly Carolin Purmann Matthew G Rees Martin Ridderstråle Susan M Ring Fernando Rivadeneira Aimo Ruokonen Manjinder S Sandhu Jouko Saramies Laura J Scott Angelo Scuteri Kaisa Silander Matthew A Sims Kijoung Song Jonathan Stephens Suzanne Stevens Heather M Stringham Y C Loraine Tung Timo T Valle Cornelia M Van Duijn Karani S Vimaleswaran Peter Vollenweider Gerard Waeber Chris Wallace Richard M Watanabe Dawn M Waterworth Nicholas Watkins Jacqueline C M Witteman Eleftheria Zeggini Guangju Zhai M Carola Zillikens David Altshuler Mark J Caulfield Stephen J Chanock I Sadaf Farooqi Luigi Ferrucci Jack M Guralnik Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Markku Laakso Vincent Mooser Ken K Ong Willem H Ouwehand Veikko Salomaa Nilesh J Samani Timothy D Spector Tiinamaija Tuomi Jaakko Tuomilehto Manuela Uda André G Uitterlinden Nicholas J Wareham Panagiotis Deloukas Timothy M Frayling Leif C Groop Richard B Hayes David J Hunter Karen L Mohlke Leena Peltonen David Schlessinger David P Strachan H-Erich Wichmann Mark I McCarthy Michael Boehnke Inês Barroso Gonçalo R Abecasis Joel N Hirschhorn

Nat Genet 2009 Jan 14;41(1):25-34. Epub 2008 Dec 14.

Genetic Investigation of ANthropometric Traits Consortium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695662PMC
January 2009

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Authors:
Ruth J F Loos Cecilia M Lindgren Shengxu Li Eleanor Wheeler Jing Hua Zhao Inga Prokopenko Michael Inouye Rachel M Freathy Antony P Attwood Jacques S Beckmann Sonja I Berndt Kevin B Jacobs Stephen J Chanock Richard B Hayes Sven Bergmann Amanda J Bennett Sheila A Bingham Murielle Bochud Morris Brown Stéphane Cauchi John M Connell Cyrus Cooper George Davey Smith Ian Day Christian Dina Subhajyoti De Emmanouil T Dermitzakis Alex S F Doney Katherine S Elliott Paul Elliott David M Evans I Sadaf Farooqi Philippe Froguel Jilur Ghori Christopher J Groves Rhian Gwilliam David Hadley Alistair S Hall Andrew T Hattersley Johannes Hebebrand Iris M Heid Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Blanca Herrera Anke Hinney Sarah E Hunt Marjo-Riitta Jarvelin Toby Johnson Jennifer D M Jolley Fredrik Karpe Andrew Keniry Kay-Tee Khaw Robert N Luben Massimo Mangino Jonathan Marchini Wendy L McArdle Ralph McGinnis David Meyre Patricia B Munroe Andrew D Morris Andrew R Ness Matthew J Neville Alexandra C Nica Ken K Ong Stephen O'Rahilly Katharine R Owen Colin N A Palmer Konstantinos Papadakis Simon Potter Anneli Pouta Lu Qi Joshua C Randall Nigel W Rayner Susan M Ring Manjinder S Sandhu André Scherag Matthew A Sims Kijoung Song Nicole Soranzo Elizabeth K Speliotes Holly E Syddall Sarah A Teichmann Nicholas J Timpson Jonathan H Tobias Manuela Uda Carla I Ganz Vogel Chris Wallace Dawn M Waterworth Michael N Weedon Cristen J Willer Wraight Xin Yuan Eleftheria Zeggini Joel N Hirschhorn David P Strachan Willem H Ouwehand Mark J Caulfield Nilesh J Samani Timothy M Frayling Peter Vollenweider Gerard Waeber Vincent Mooser Panos Deloukas Mark I McCarthy Nicholas J Wareham Inês Barroso Kevin B Jacobs Stephen J Chanock Richard B Hayes Claudia Lamina Christian Gieger Thomas Illig Thomas Meitinger H-Erich Wichmann Peter Kraft Susan E Hankinson David J Hunter Frank B Hu Helen N Lyon Benjamin F Voight Martin Ridderstrale Leif Groop Paul Scheet Serena Sanna Goncalo R Abecasis Giuseppe Albai Ramaiah Nagaraja David Schlessinger Anne U Jackson Jaakko Tuomilehto Francis S Collins Michael Boehnke Karen L Mohlke

Nat Genet 2008 Jun 4;40(6):768-75. Epub 2008 May 4.

MRC Epidemiology Unit, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ng.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2669167PMC
June 2008

Information capture using SNPs from HapMap and whole-genome chips differs in a sample of inflammatory and cardiovascular gene-centric regions from genome-wide estimates.

Genome Res 2007 Nov 25;17(11):1596-602. Epub 2007 Sep 25.

Clinical Pharmacology and the Genome Centre, William Harvey Research Institute, Bart's and The London School of Medicine and Dentistry, London EC1M 6BQ, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2045142PMC
November 2007

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

Linkage analysis using co-phenotypes in the BRIGHT study reveals novel potential susceptibility loci for hypertension.

Am J Hum Genet 2006 Aug 19;79(2):323-31. Epub 2006 Jun 19.

Clinical Pharmacology and The Genome Centre, The William Harvey Research Institute, Barts and The London, Queen Mary's School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1086/506370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559504PMC
August 2006

Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.

Hum Mol Genet 2006 Apr 16;15(8):1365-74. Epub 2006 Mar 16.

Department of Cardiovascular Medicine and Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.

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April 2006

Improved power offered by a score test for linkage disequilibrium mapping of quantitative-trait loci by selective genotyping.

Am J Hum Genet 2006 Mar 5;78(3):498-504. Epub 2006 Jan 5.

Department of Clinical Pharmacology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1380292PMC
March 2006

Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.

Hum Mol Genet 2005 Jul 11;14(13):1805-14. Epub 2005 May 11.

Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and the London School of Medicine, London, UK.

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July 2005

Estimating the relative recurrence risk ratio using a global cross-ratio model.

Genet Epidemiol 2003 Dec;25(4):293-302

London School of Hygiene and Tropical Medicine, IDEU, London, UK.

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December 2003

Estimating the relative recurrence risk ratio for leprosy in Karonga District, Malawi.

Lepr Rev 2003 Jun;74(2):133-40

London School of Hygiene and Tropical Medicine, IDEU, Keppel Street, London WC1E 7HT, UK.

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June 2003

Trends in drug overdose deaths in England and Wales 1993-98: methadone does not kill more people than heroin.

Addiction 2003 Apr;98(4):419-25

Centre for Research on Drugs and Health Behaviour, Social Science and Medicine, Imperial College, London, UK.

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April 2003