Chris Tselepis

Chris Tselepis

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Chris Tselepis

Chris Tselepis

Publications by authors named "Chris Tselepis"

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40Publications

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The Safety and Tolerability of a Potential Alginate-Based Iron Chelator; Results of A Healthy Participant Study.

Nutrients 2019 Mar 21;11(3). Epub 2019 Mar 21.

Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.3390/nu11030674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471009PMC
March 2019

A potential role for hepcidin in obesity-driven colorectal tumourigenesis.

Oncol Rep 2018 Jan 31;39(1):392-400. Epub 2017 Oct 31.

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2TT, UK.

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http://www.spandidos-publications.com/10.3892/or.2017.6062
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http://dx.doi.org/10.3892/or.2017.6062DOI Listing
January 2018

Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q.

J Pathol Clin Res 2017 Jul 14;3(3):155-170. Epub 2017 Jul 14.

Cancer Immunology and Immunotherapy Centre, Institute of Immunology and ImmunotherapyUniversity of BirminghamEdgbaston, BirminghamUK.

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http://dx.doi.org/10.1002/cjp2.70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527318PMC
July 2017

Modulation of iron transport, metabolism and reactive oxygen status by quercetin-iron complexes in vitro.

Mol Nutr Food Res 2017 03 13;61(3). Epub 2016 Dec 13.

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, England, UK.

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http://dx.doi.org/10.1002/mnfr.201600692DOI Listing
March 2017

Morphology of the ferritin iron core by aberration corrected scanning transmission electron microscopy.

Nanotechnology 2016 Nov 13;27(46):46LT02. Epub 2016 Oct 13.

Nanoscale Physics Research Laboratory, School of Physics and Astronomy, University of Birmingham, Birmingham B15 2TT, UK.

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http://dx.doi.org/10.1088/0957-4484/27/46/46LT02DOI Listing
November 2016

The chelation of colonic luminal iron by a unique sodium alginate for the improvement of gastrointestinal health.

Mol Nutr Food Res 2016 09 9;60(9):2098-108. Epub 2016 Jun 9.

Institute of Cancer and Genomic Science, University of Birmingham, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1002/mnfr.201500882DOI Listing
September 2016

Alginate-Iron Speciation and Its Effect on In Vitro Cellular Iron Metabolism.

PLoS One 2015 17;10(9):e0138240. Epub 2015 Sep 17.

University of Birmingham, School of Cancer Sciences, College of Medical and Dental Sciences, Vincent Drive, Edgbaston, Birmingham, B15 2TT, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138240PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574481PMC
June 2016

Serum hepcidin-25 and response to intravenous iron in patients with non-dialysis chronic kidney disease.

J Nephrol 2015 Feb 1;28(1):81-8. Epub 2014 Apr 1.

Renal Department, First Floor, Centre for Translational Inflammation Research, Queen Elizabeth Hospital Birmingham, University of Birmingham, Birmingham, B15 2WB, UK,

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http://dx.doi.org/10.1007/s40620-014-0083-yDOI Listing
February 2015

Organometallic nucleoside analogues with ferrocenyl linker groups: synthesis and cancer cell line studies.

J Med Chem 2014 Jul 20;57(13):5817-22. Epub 2014 Jun 20.

School of Chemistry, ‡School of Cancer Sciences, College of Medical and Dental Sciences, §School of Biosciences, College of Life and Environmental Sciences, and ∥School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham , Edgbaston, Birmingham, B15 2TT, U.K.

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http://pubs.acs.org/doi/10.1021/jm500246h
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http://dx.doi.org/10.1021/jm500246hDOI Listing
July 2014

Iron chelation in the treatment of cancer: a new role for deferasirox?

J Clin Pharmacol 2013 Sep 6;53(9):885-91. Epub 2013 Jun 6.

School of Cancer Studies, Department of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/jcph.113DOI Listing
September 2013

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action.

Mol Pharmacol 2013 Jan 16;83(1):179-90. Epub 2012 Oct 16.

Iron Metabolism and Chelation Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales, 2006 Australia.

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http://dx.doi.org/10.1124/mol.112.081893DOI Listing
January 2013

Cadherin switching and bladder cancer.

J Urol 2010 Aug 17;184(2):423-31. Epub 2010 Jun 17.

School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1016/j.juro.2010.04.016DOI Listing
August 2010

Is iron overload in alcohol-related cirrhosis mediated by hepcidin?

World J Gastroenterol 2009 Dec;15(46):5864-6

Department of Gastroenterology, University Hospital Birmingham, Vincent Drive, Birmingham B15 2TH, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791283PMC
http://dx.doi.org/10.3748/wjg.15.5864DOI Listing
December 2009

Differential ferritin expression is associated with iron deficiency in coeliac disease.

Eur J Gastroenterol Hepatol 2009 Jul;21(7):794-804

Institute for Cancer Studies, University of Birmingham Cancer Research, UK.

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http://dx.doi.org/10.1097/MEG.0b013e328308676bDOI Listing
July 2009

Proteomic profiling of urine for the detection of colon cancer.

Proteome Sci 2008 Jun 16;6:19. Epub 2008 Jun 16.

Cancer Research UK Institute for Cancer Studies, University of Birmingham, Edgbaston, UK.

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http://dx.doi.org/10.1186/1477-5956-6-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440369PMC
June 2008

Epithelial-mesenchymal transition mediated tumourigenesis in the gastrointestinal tract.

World J Gastroenterol 2008 Jun;14(24):3792-7

The Medical School, University of Birmingham, Birmingham, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721434PMC
http://dx.doi.org/10.3748/wjg.14.3792DOI Listing
June 2008

Increased hepcidin expression in colorectal carcinogenesis.

World J Gastroenterol 2008 Mar;14(9):1339-45

CRUK Institute for Cancer Studies, University of Birmingham, Vincent Drive, Birmingham B15 2TH, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693679PMC
http://dx.doi.org/10.3748/wjg.14.1339DOI Listing
March 2008

Overexpression of Slug is associated with malignant progression of esophageal adenocarcinoma.

World J Gastroenterol 2008 Feb;14(7):1044-52

CRUK Institute for Cancer Studies, University of Birmingham, Vincent Drive, Birmingham B15 2TH, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689407PMC
http://dx.doi.org/10.3748/wjg.14.1044DOI Listing
February 2008

Snail family transcription factors are implicated in thyroid carcinogenesis.

Am J Pathol 2007 Sep;171(3):1037-46

Tissue Injury and Repair Group, Centre for Regenerative Medicine, University of Edinburgh, Division of Clinical and Surgical Sciences, Room FU501, Chancellors Bldg, 49 Little France Crescent, Edinburgh EH16 4SB, UK.

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http://dx.doi.org/10.2353/ajpath.2007.061211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1959496PMC
September 2007

The effect of alginates on deoxycholic-acid-induced changes in oesophageal mucosal biology at pH 4.

J Biomater Sci Polym Ed 2007 ;18(3):317-33

Technostics, The Deep Business Centre, Kingston Upon Hull, East Yorkshire, HU1 4BG, UK.

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http://dx.doi.org/10.1163/156856207779996922DOI Listing
August 2007

Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes.

J Biol Chem 2006 Jul 17;281(30):21321-31. Epub 2006 May 17.

School of Biosciences and School of Medicine, University of Birmingham, Edgbaston, UK.

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http://dx.doi.org/10.1074/jbc.M509731200DOI Listing
July 2006

Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.

J Immunol 2006 Jul;177(1):593-603

Liver Research Laboratories, Medical Research Council for Immune Regulation, Institute for Biomedical Research, University of Birmingham, Birmingham B15 2TH, UK.

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http://dx.doi.org/10.4049/jimmunol.177.1.593DOI Listing
July 2006

A role for tumour necrosis factor alpha in human small bowel iron transport.

Biochem J 2005 Sep;390(Pt 2):437-46

Division of Medical Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TH, UK.

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http://dx.doi.org/10.1042/BJ20050256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1198923PMC
September 2005

Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action.

Oncogene 2002 Sep;21(39):6071-81

Epithelial Laboratory and CRVK Laboratory, Queen Elizabeth Hospital, University of Birmingham, Birmingham B15 2TH, UK.

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http://dx.doi.org/10.1038/sj.onc.1205731DOI Listing
September 2002

Transient P-cadherin expression in radiation proctitis; a model of mucosal injury and repair.

J Pathol 2002 Jun;197(2):194-200

Department of Surgery, Clinical Research Institute, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1002/path.1092DOI Listing
June 2002