Publications by authors named "Chris Probert"

78Publications

Using Volatile Organic Compounds to Investigate the Effect of Oral Iron Supplementation on the Human Intestinal Metabolome.

Molecules 2020 Nov 3;25(21). Epub 2020 Nov 3.

The Henry Wellcome Laboratory, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool L69 3BX, UK.

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http://dx.doi.org/10.3390/molecules25215113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7662922PMC
November 2020

Depression, anxiety, and loneliness among adolescents and young adults with IBD in the UK: the role of disease severity, age of onset, and embarrassment of the condition.

Qual Life Res 2020 Sep 30. Epub 2020 Sep 30.

Children, Young People and Families, Faculty of Health, Social Care & Medicine, Edge Hill University, St Helens Road, Ormskirk, L39 4QP, UK.

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http://dx.doi.org/10.1007/s11136-020-02653-9DOI Listing
September 2020

Prevalence of COVID-19 Symptoms among Inflammatory Bowel Disease Patients Treated with Biological Agents.

J Crohns Colitis 2020 Sep 11. Epub 2020 Sep 11.

Department of Gastroenterology, Liverpool University Foundation Hospitals NHS Trust, Liverpool, UK.

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http://dx.doi.org/10.1093/ecco-jcc/jjaa187DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543299PMC
September 2020

Editorial: peristomal pyoderma gangrenosum-a challenge for patients, healthcare professionals and research.

Aliment Pharmacol Ther 2020 07;52(2):404-405

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/apt.15822DOI Listing
July 2020

Review article: impact of cigarette smoking on intestinal inflammation-direct and indirect mechanisms.

Aliment Pharmacol Ther 2020 06 5;51(12):1268-1285. Epub 2020 May 5.

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/apt.15774DOI Listing
June 2020

Faecal volatile organic compounds in preterm babies at risk of necrotising enterocolitis: the DOVE study.

Arch Dis Child Fetal Neonatal Ed 2020 Sep 23;105(5):474-479. Epub 2019 Dec 23.

Neonatal Unit, Birmingham Women's and Children's Hospital NHS Foundation Trust, Birmingham, UK

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http://dx.doi.org/10.1136/archdischild-2019-318221DOI Listing
September 2020

Commentary: vitamin D supplementation in Crohn's disease.

Authors:
Chris Probert

Aliment Pharmacol Ther 2020 01;51(1):201-202

Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1111/apt.15524DOI Listing
January 2020

Microscopic colitis: diagnosis and management.

Frontline Gastroenterol 2019 Oct 27;10(4):388-393. Epub 2018 Nov 27.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1136/flgastro-2018-101040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788131PMC
October 2019

The Proof for Oral Crohn's Disease Is in the Cinnamon-free Pudding.

Clin Gastroenterol Hepatol 2020 Dec 11;18(13):e154. Epub 2019 Sep 11.

The Pennine Acute Hospitals NHS Trust, Section of IBD - Division of Gastroenterology, Manchester, United Kingdom; Manchester Academic Health Science Centre, Manchester, United Kingdom.

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http://dx.doi.org/10.1016/j.cgh.2019.09.005DOI Listing
December 2020

A longitudinal study of the faecal microbiome and metabolome of periparturient mares.

PeerJ 2019 3;7:e6687. Epub 2019 Apr 3.

Department of Epidemiology and Population Health, Institute of Infection and Global Health, University of Liverpool, Leahurst campus, Wirral, UK.

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https://peerj.com/articles/6687
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http://dx.doi.org/10.7717/peerj.6687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451438PMC
April 2019

Volatile organic compounds emitted from faeces as a biomarker for colorectal cancer.

Aliment Pharmacol Ther 2019 04 3;49(8):1005-1012. Epub 2019 Mar 3.

Royal Liverpool and Broadgreen University Hospital Trust, Liverpool, UK.

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http://dx.doi.org/10.1111/apt.15140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593415PMC
April 2019

Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice.

FASEB J 2019 03 25;33(3):3129-3136. Epub 2018 Oct 25.

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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https://www.fasebj.org/doi/10.1096/fj.201800076RR
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http://dx.doi.org/10.1096/fj.201800076RRDOI Listing
March 2019

Oral iron exacerbates colitis and influences the intestinal microbiome.

PLoS One 2018 11;13(10):e0202460. Epub 2018 Oct 11.

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202460PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181268PMC
March 2019

Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial.

Eur J Nutr 2019 Jun 19;58(4):1735-1745. Epub 2018 May 19.

Faculty of Kinesiology, University of Calgary, 2500 University Drive NW, Calgary, AB, T2N 1N4, Canada.

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http://dx.doi.org/10.1007/s00394-018-1721-2DOI Listing
June 2019

Oral budesonide in gastrointestinal and liver disease: A practical guide for the clinician.

J Gastroenterol Hepatol 2018 Mar 30. Epub 2018 Mar 30.

Department of Gastroenterology, Institute of Translational Medicine, Liverpool, UK.

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http://dx.doi.org/10.1111/jgh.14151DOI Listing
March 2018

Volatile Organic Compounds in Feces Associate With Response to Dietary Intervention in Patients With Irritable Bowel Syndrome.

Clin Gastroenterol Hepatol 2018 03 7;16(3):385-391.e1. Epub 2017 Oct 7.

Department of Nutritional Sciences, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.09.055DOI Listing
March 2018

Dual-focus Magnification, High-Definition Endoscopy Improves Pathology Detection in Direct-to-Test Diagnostic Upper Gastrointestinal Endoscopy.

J Gastrointestin Liver Dis 2017 Mar;26(1):19-24

Department of Gastroenterology, Royal Liverpool and Broadgreen University Hospital Trust, Liverpool, UK.

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http://dx.doi.org/10.15403/jgld.2014.1121.261.genDOI Listing
March 2017

The use of randomisation-based efficacy estimators in non-inferiority trials.

Trials 2017 03 9;18(1):117. Epub 2017 Mar 9.

Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.

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http://dx.doi.org/10.1186/s13063-017-1837-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343391PMC
March 2017

Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury.

Pharmacol Ther 2017 Apr 27;172:181-194. Epub 2017 Jan 27.

MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.pharmthera.2017.01.002DOI Listing
April 2017

Giardiasis.

BMJ 2016 Oct 27;355:i5369. Epub 2016 Oct 27.

Wingate Medical Centre, Kirkby L33 6YJ, UK

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http://dx.doi.org/10.1136/bmj.i5369DOI Listing
October 2016

New-Generation High-Definition Colonoscopes Increase Adenoma Detection when Screening a Moderate-Risk Population for Colorectal Cancer.

Clin Colorectal Cancer 2017 03 21;16(1):44-50. Epub 2016 Jul 21.

Department of Gastroenterology and Hepatology, Royal Liverpool and Broadgreen University Hospital Trust, Liverpool, UK; Clinical Cancer Trials Unit, University of Liverpool, Liverpool, UK. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2016.07.006DOI Listing
March 2017

Validation of a Simple 0 to 10 Numerical Score (IBD-10) of Patient-reported Inflammatory Bowel Disease Activity for Routine Clinical Use.

Inflamm Bowel Dis 2016 08;22(8):1902-7

*Department of Gastroenterology, Royal Liverpool University Hospital, Liverpool, United Kingdom;†Cancer Research UK, Liverpool Cancer Trials Unit, Liverpool, United Kingdom; and‡Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0000000000000803DOI Listing
August 2016

Correlation between Faecal Tumour M2 Pyruvate Kinase and Colonoscopy for the Detection of Adenomatous Neoplasia in a Secondary Care Cohort.

J Gastrointestin Liver Dis 2016 Mar;25(1):71-7

Unit of Gastroenterology Research, Dept of Molecular and Cellular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.15403/jgld.2014.1121.251.m2pDOI Listing
March 2016

Biosimilars: what's around the corner?

Frontline Gastroenterol 2015 Oct 20;6(4):262-263. Epub 2015 Jul 20.

Gastroenterology Research Unit, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1136/flgastro-2015-100587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369612PMC
October 2015

Managing acute severe ulcerative colitis in the hosptialised setting.

Frontline Gastroenterol 2015 Oct 8;6(4):241-245. Epub 2014 Jul 8.

Department of Gastroenterology, University of Liverpool, UK.

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http://dx.doi.org/10.1136/flgastro-2014-100459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369586PMC
October 2015

Investigation of Volatile Organic Compounds Emitted from Faeces for the Diagnosis of Giardiasis.

J Gastrointestin Liver Dis 2015 Sep;24(3):281-6

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://www.jgld.ro/wp/archive/y2015/n3/a4
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http://dx.doi.org/10.15403/jgld.2014.1121.243.aboDOI Listing
September 2015

Body Mass Index and Smoking Affect Thioguanine Nucleotide Levels in Inflammatory Bowel Disease.

J Crohns Colitis 2015 Aug 12;9(8):640-6. Epub 2015 May 12.

Department of Gastroenterology, Royal Liverpool University Hospital, Liverpool, UK

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http://dx.doi.org/10.1093/ecco-jcc/jjv084DOI Listing
August 2015

Identifying and quantifying metabolites by scoring peaks of GC-MS data.

BMC Bioinformatics 2014 Dec 10;15:374. Epub 2014 Dec 10.

The University of Auckland, 3A Symonds Street, Auckland, 1142, New Zealand.

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http://dx.doi.org/10.1186/s12859-014-0374-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307155PMC
December 2014

Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?

Expert Rev Clin Immunol 2014 Sep 28;10(9):1129-31. Epub 2014 Jul 28.

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3BX, UK.

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http://dx.doi.org/10.1586/1744666X.2014.943664DOI Listing
September 2014

Future methods for the diagnosis of inflammatory bowel disease.

Dig Dis 2014 23;32(4):463-7. Epub 2014 Jun 23.

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1159/000358153DOI Listing
February 2015

Population-based screening in colorectal cancer - current practice and future developments: faecal biomarkers review.

J Gastrointestin Liver Dis 2014 Jun;23(2):195-202

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.15403/jgld.2014.1121.232.dsw1DOI Listing
June 2014

A rare cause of weight loss.

Gut 2014 Jun 25;63(6):1024, 1027. Epub 2013 Nov 25.

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, , Liverpool, UK.

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http://dx.doi.org/10.1136/gutjnl-2013-306299DOI Listing
June 2014

The liver breath! Breath volatile organic compounds for the diagnosis of liver disease.

Clin Gastroenterol Hepatol 2014 Mar 7;12(3):524-6. Epub 2013 Nov 7.

Department of Gastroenterology, University of Liverpool, Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/j.cgh.2013.10.032DOI Listing
March 2014

An investigation of fecal volatile organic metabolites in irritable bowel syndrome.

PLoS One 2013 13;8(3):e58204. Epub 2013 Mar 13.

Department of Gastroenterology, University of Bristol/Bristol Royal Infirmary, Bristol, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058204PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596408PMC
September 2013

Fecal microbiome and volatile organic compound metabolome in obese humans with nonalcoholic fatty liver disease.

Clin Gastroenterol Hepatol 2013 Jul 27;11(7):868-75.e1-3. Epub 2013 Feb 27.

Department of Medicine, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1016/j.cgh.2013.02.015DOI Listing
July 2013

Steroids and 5-aminosalicylic acids in moderate ulcerative colitis: addressing the dilemma.

Authors:
Chris Probert

Therap Adv Gastroenterol 2013 Jan;6(1):33-8

Department of Gastroenterology, The Henry Wellcome Laboratory, Institute of Translational Medicine, University of Liverpool, Nuffield Building, Crown Street, Liverpool L69 3GE, UK.

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http://dx.doi.org/10.1177/1756283X12461395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539295PMC
January 2013

Mixed fortunes in the treatment of Crohn's disease.

Lancet 2012 Jun;379(9832):2212

Department of Gastroenterology, Bristol Royal Infirmary, University Hospitals Bristol Trust, Bristol, UK.

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http://dx.doi.org/10.1016/S0140-6736(12)60359-6DOI Listing
June 2012

Role of faecal gas analysis for the diagnosis of IBD.

Biochem Soc Trans 2011 Aug;39(4):1079-80

Level 7, Bristol Royal Infirmary, Marlborough Street, Bristol BS2 8HW, UK.

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http://dx.doi.org/10.1042/BST0391079DOI Listing
August 2011

The molecular biology of inflammatory bowel diseases.

Biochem Soc Trans 2011 Aug;39(4):1057-60

Mucin Research Group, School of Clinical Sciences, Bristol Royal Infirmary, Level 7, Marlborough Street, Bristol BS2 8HW, UK.

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http://dx.doi.org/10.1042/BST0391057DOI Listing
August 2011

Can 11β-hydroxysteroid dehydrogenase activity predict the sensitivity of bone to therapeutic glucocorticoids in inflammatory bowel disease?

Calcif Tissue Int 2011 Sep 22;89(3):246-51. Epub 2011 Jun 22.

Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, University of Birmingham, UK.

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http://dx.doi.org/10.1007/s00223-011-9512-2DOI Listing
September 2011

A costly diagnostic failure.

J Fam Pract 2010 Nov;59(11):624-6

Gastroenterology Department, Bristol Royal Infi rmary, UK.

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November 2010

Best practice in the management of mild-to-moderately active ulcerative colitis and achieving maintenance of remission using mesalazine.

Eur J Gastroenterol Hepatol 2010 Aug;22(8):912-6

Gastrointestinal Unit, Medical Section, Herlev Hospital, University of Copenhagen, DK-2730 Herlev, Denmark.

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http://dx.doi.org/10.1097/meg.0b013e32833944bfDOI Listing
August 2010

Clinical experience of methotrexate in Crohn's disease: response, safety and monitoring of treatment.

Postgrad Med J 2010 Apr;86(1014):208-11

Department of Gastroenterology, Bristol Royal Infirmary, Lower Marlborough Street, Bristol BS2 8HW, UK.

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http://dx.doi.org/10.1136/pgmj.2009.085787DOI Listing
April 2010

IL-6 may modulate the skeletal response to glucocorticoids during exacerbations of inflammatory bowel disease.

Calcif Tissue Int 2010 May 14;86(5):375-81. Epub 2010 Mar 14.

Clinical Science at South Bristol, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1007/s00223-010-9345-4DOI Listing
May 2010

Volatile organic compounds as diagnostic biomarkers in gastrointestinal and liver diseases.

J Gastrointestin Liver Dis 2009 Sep;18(3):337-43

Clinical Science at South Bristol, University of Bristol, Level 7 CSSB, Bristol Royal Infirmary, Upper Maudlin Street, Bristol, UK, BS2 8HW.

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September 2009

Analysis of faecal volatile organic compounds in preterm infants who develop necrotising enterocolitis: a pilot study.

J Pediatr Gastroenterol Nutr 2009 Nov;49(5):559-65

Clinical Science at South Bristol, Bristol Royal Infirmary, Marlborough St, Bristol, UK.

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http://dx.doi.org/10.1097/MPG.0b013e3181a3bfbcDOI Listing
November 2009

Are there any ethnic groups that are more likely to develop IBD?

Inflamm Bowel Dis 2008 Oct;14 Suppl 2:S24-5

Division of Gastroenterology, Clinical Sciences at South Bristol, British Royal Infirmary, Bristol, UK.

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http://dx.doi.org/10.1002/ibd.20601DOI Listing
October 2008

Is once-daily dosing of mesalazine effective for maintenance of remission in patients with ulcerative colitis?

Nat Clin Pract Gastroenterol Hepatol 2008 Nov 16;5(11):596-7. Epub 2008 Sep 16.

University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/ncpgasthep1255DOI Listing
November 2008

Volatile organic compounds from feces and their potential for diagnosis of gastrointestinal disease.

FASEB J 2007 Jun 21;21(8):1675-88. Epub 2007 Feb 21.

Clinical Science at South Bristol, Bristol Royal Infirmary, Marlborough St., Bristol BS2 8HW, UK.

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http://dx.doi.org/10.1096/fj.06-6927comDOI Listing
June 2007

Acute tryptophan depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome.

Am J Gastroenterol 2006 Nov 4;101(11):2582-7. Epub 2006 Oct 4.

Clinical Science at South Bristol, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1111/j.1572-0241.2006.00811.xDOI Listing
November 2006

Diagnosis and treatment of pyoderma gangrenosum.

BMJ 2006 Jul;333(7560):181-4

Cheltenham General Hospital, Cheltenham GL53 7AN.

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http://dx.doi.org/10.1136/bmj.333.7560.181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513476PMC
July 2006

Refractory coeliac disease: remission with infliximab and immunomodulators.

Eur J Gastroenterol Hepatol 2005 Jun;17(6):667-9

Department of Gastroenterology, Bristol Royal Infirmary, Marlborough Street, Bristol, UK.

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http://dx.doi.org/10.1097/00042737-200506000-00012DOI Listing
June 2005

Incidence of inflammatory bowel disease is rising and abdominal tuberculosis is falling in Bangladeshis in East London, United Kingdom.

Am J Gastroenterol 2004 Sep;99(9):1749-55

Academic Departments of Adult and Paediatric Gastroenterology and of Histopathology, Barts and The London, Queen Mary School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1111/j.1572-0241.2004.30445.xDOI Listing
September 2004

A Crohn's repertoire: T cell receptor gammadelta.

Inflamm Bowel Dis 2003 May;9(3):213-4

University of Bristol, Bristol Royal Infirmary, UK.

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May 2003

Evidence for the clinical use of infliximab in Crohn's disease.

Rom J Gastroenterol 2003 Mar;12(1):2-5

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March 2003

Teaching sexual history taking to medical students and examining it: experience in one medical school and a national survey.

Med Educ 2003 Feb;37(2):94-8

Department of Genitourinary Medicine, Taunton and Somerset NHS Trust, Taunton and Somerset Hospital, UK.

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http://dx.doi.org/10.1046/j.1365-2923.2003.01411.xDOI Listing
February 2003