Chris P Ponting

Chris P Ponting

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Chris P Ponting

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Biologically indeterminate yet ordered promiscuous gene expression in single medullary thymic epithelial cells.

EMBO J 2020 Jan 28;39(1):e101828. Epub 2019 Oct 28.

MRC Human Genetics Unit, MRC IGMM, The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.15252/embj.2019101828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939203PMC
January 2020

Hexa-Longin domain scaffolds for inter-Rab signalling.

Bioinformatics 2019 Sep 28. Epub 2019 Sep 28.

Medical Research Council Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1093/bioinformatics/btz739DOI Listing
September 2019

The Human Cell Atlas: making 'cell space' for disease.

Authors:
Chris P Ponting

Dis Model Mech 2019 02 1;12(2). Epub 2019 Feb 1.

MRC Human Genetics Unit, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK

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http://dx.doi.org/10.1242/dmm.037622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398500PMC
February 2019

A gene expression signature in developing Purkinje cells predicts autism and intellectual disability co-morbidity status.

Sci Rep 2019 Jan 24;9(1):485. Epub 2019 Jan 24.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, United Kingdom.

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http://dx.doi.org/10.1038/s41598-018-37284-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346046PMC
January 2019

The Cdk8/19-cyclin C transcription regulator functions in genome replication through metazoan Sld7.

PLoS Biol 2019 01 29;17(1):e2006767. Epub 2019 Jan 29.

Vertebrate DNA Replication Lab, Centre for Medical Biotechnology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1371/journal.pbio.2006767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377148PMC
January 2019

Complexities of post-transcriptional regulation and the modeling of ceRNA crosstalk.

Crit Rev Biochem Mol Biol 2018 06 23;53(3):231-245. Epub 2018 Mar 23.

a MRC Human Genetics Unit within the Institute of Genetics and Molecular Medicine , University of Edinburgh , Edinburgh , UK.

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http://dx.doi.org/10.1080/10409238.2018.1447542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935048PMC
June 2018

TMEM132: an ancient architecture of cohesin and immunoglobulin domains define a new family of neural adhesion molecules.

Bioinformatics 2018 Mar;34(5):721-724

Medical Research Council Human Genetics Unit, IGMM, University of Edinburgh, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1093/bioinformatics/btx689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030884PMC
March 2018

Biological function in the twilight zone of sequence conservation.

Authors:
Chris P Ponting

BMC Biol 2017 08 16;15(1):71. Epub 2017 Aug 16.

MRC Human Genetics Unit, The Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK.

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http://dx.doi.org/10.1186/s12915-017-0411-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558704PMC
August 2017

Identification of genetic variants affecting vitamin D receptor binding and associations with autoimmune disease.

Hum Mol Genet 2017 06;26(11):2164-2176

Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1093/hmg/ddx092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886188PMC
June 2017

Single-Cell Multiomics: Multiple Measurements from Single Cells.

Trends Genet 2017 02 13;33(2):155-168. Epub 2017 Jan 13.

Sanger Institute - EBI Single-Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK; Department of Human Genetics, University of Leuven, KU Leuven, Leuven, 3000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2016.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303816PMC
February 2017

Functional RNA classes: a matter of time?

Nat Struct Mol Biol 2017 01;24(1):7-8

MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, UK.

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http://dx.doi.org/10.1038/nsmb.3354DOI Listing
January 2017

An open and transparent process to select ELIXIR Node Services as implemented by ELIXIR-UK.

F1000Res 2016 21;5. Epub 2016 Dec 21.

School of Computer Science, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.12688/f1000research.10473.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265702PMC
December 2016

Separation and parallel sequencing of the genomes and transcriptomes of single cells using G&T-seq.

Nat Protoc 2016 11 29;11(11):2081-103. Epub 2016 Sep 29.

Sanger Institute-EBI Single-Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, UK.

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http://dx.doi.org/10.1038/nprot.2016.138DOI Listing
November 2016

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair.

J Cell Sci 2016 10 1;129(20):3845-3858. Epub 2016 Sep 1.

Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK

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http://dx.doi.org/10.1242/jcs.193375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087659PMC
October 2016

Insights into the post-transcriptional regulation of the mitochondrial electron transport chain.

Biochem Soc Trans 2016 10;44(5):1491-1498

Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, University of Edinburgh, Edinburgh, U.K.

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http://dx.doi.org/10.1042/BST20160100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095899PMC
October 2016

Long noncoding RNAs in B-cell development and activation.

Blood 2016 08 5;128(7):e10-9. Epub 2016 Jul 5.

The Francis Crick Institute, London, United Kingdom; Imperial College, London, United Kingdom.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2015-11
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http://dx.doi.org/10.1182/blood-2015-11-680843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000579PMC
August 2016

Vasohibins: new transglutaminase-like cysteine proteases possessing a non-canonical Cys-His-Ser catalytic triad.

Bioinformatics 2016 05 21;32(10):1441-5. Epub 2016 Jan 21.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1093/bioinformatics/btv761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866520PMC
May 2016

High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets.

Genet Med 2016 Jan 12;18(1):41-8. Epub 2015 Mar 12.

Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/gim.2015.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486368PMC
January 2016

Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick.

Neural Dev 2016 Jan 27;11. Epub 2016 Jan 27.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1186/s13064-016-0057-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730756PMC
January 2016

The RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeast.

PLoS One 2014 4;9(8):e104161. Epub 2014 Aug 4.

Wellcome Trust Centre for Cell Biology and Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104161PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121317PMC
November 2015

Temporal transcriptomics suggest that twin-peaking genes reset the clock.

Elife 2015 Nov 2;4. Epub 2015 Nov 2.

MRC Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.7554/eLife.10518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718813PMC
November 2015

REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans.

Genes Dev 2015 Sep;29(18):1969-79

DNA Damage Response Laboratory, The Francis Crick Institute, South Mimms EN3 3LD, United Kingdom; Clare Hall Laboratories, The Francis Crick Institute, South Mimms EN3 3LD, United Kingdom;

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http://genesdev.cshlp.org/content/29/18/1969.full.pdf
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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.266056.115
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http://dx.doi.org/10.1101/gad.266056.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579353PMC
September 2015

Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex.

Neurobiol Aging 2015 Aug 25;36(8):2443.e9-2443.e20. Epub 2015 Apr 25.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK; Department of Physiology, Anatomy and Genetics, MRC Functional Genomics Unit, University of Oxford, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503803PMC
http://dx.doi.org/10.1016/j.neurobiolaging.2015.04.008DOI Listing
August 2015

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes.

Nat Methods 2015 Jun 27;12(6):519-22. Epub 2015 Apr 27.

1] Sanger Institute-EBI Single-Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, UK. [2] Department of Human Genetics, University of Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/nmeth.3370DOI Listing
June 2015

No gene in the genome makes sense except in the light of evolution.

Annu Rev Genomics Hum Genet 2014 24;15:71-92. Epub 2014 Apr 24.

MRC Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom; email: ,

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http://dx.doi.org/10.1146/annurev-genom-090413-025621DOI Listing
May 2015

Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells.

Genome Res 2015 May 19;25(5):655-66. Epub 2015 Mar 19.

MRC Functional Genomics Unit, University of Oxford, Oxford OX1 3QX, United Kingdom; University of Oxford, Department of Physiology, Anatomy and Genetics, Oxford OX1 3QX, United Kingdom; Department of Physiology, University of Lausanne, 1005 Lausanne, Switzerland;

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http://genome.cshlp.org/lookup/doi/10.1101/gr.181974.114
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http://dx.doi.org/10.1101/gr.181974.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417114PMC
May 2015

Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes.

Genome Res 2015 Feb 3;25(2):226-34. Epub 2014 Nov 3.

Systems Biology Laboratory UK, Abingdon, Oxfordshire OX14 4SA, United Kingdom; Department of Oncology, Division of Cellular and Molecular Medicine, St. George's, University of London, London SW17 0QT, United Kingdom.

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http://dx.doi.org/10.1101/gr.179770.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315296PMC
February 2015

RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts.

Genome Res 2015 Jan;25(1):1-13

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom;

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http://dx.doi.org/10.1101/gr.181990.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317164PMC
January 2015

TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease.

Front Genet 2014 11;5:439. Epub 2014 Dec 11.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford Oxford, UK.

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http://dx.doi.org/10.3389/fgene.2014.00439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263179PMC
January 2015

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.

Genome Res 2014 Dec 15;24(12):1918-31. Epub 2014 Sep 15.

Paediatric Immunology, Department of Biomedicine, University of Basel, and The Basel University Children's Hospital, Basel, 4058, Switzerland; Developmental Immunology, Department of Paediatrics, and the Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1101/gr.171645.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248310PMC
December 2014

The long non-coding RNA Dali is an epigenetic regulator of neural differentiation.

Elife 2014 Nov 21;3:e04530. Epub 2014 Nov 21.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.

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https://elifesciences.org/articles/04530
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http://dx.doi.org/10.7554/eLife.04530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383022PMC
November 2014

The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

Cell Rep 2014 Nov 13;9(4):1482-94. Epub 2014 Nov 13.

MRC Human Genetics Unit, IGMM, University of Edinburgh, Crewe Road, Edinburgh EH4 2XU, UK; Department of Molecular Biosciences, Wenner Gren Institute, Stockholm University, 106 91 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542304PMC
November 2014

The genomic substrate for adaptive radiation in African cichlid fish.

Nature 2014 Sep 3;513(7518):375-381. Epub 2014 Sep 3.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/nature13726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353498PMC
September 2014

Intergenic lncRNAs and the evolution of gene expression.

Curr Opin Genet Dev 2014 Aug 21;27:48-53. Epub 2014 May 21.

MRC Functional Genomics Unit, University of Oxford, South Parks Road, OX1 3QX, UK; University of Oxford, Department of Physiology, Anatomy and Genetics, South Parks Road, OX1 3QX, UK.

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http://dx.doi.org/10.1016/j.gde.2014.03.009DOI Listing
August 2014

Transcriptional regulatory functions of nuclear long noncoding RNAs.

Trends Genet 2014 Aug 25;30(8):348-55. Epub 2014 Jun 25.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3PT, UK. Electronic address:

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http://www.cell.com/trends/genetics/pdf/S0168-9525(14)00086-
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http://linkinghub.elsevier.com/retrieve/pii/S016895251400086
Publisher Site
http://dx.doi.org/10.1016/j.tig.2014.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115187PMC
August 2014

Considerations when investigating lncRNA function in vivo.

Elife 2014 Aug 14;3:e03058. Epub 2014 Aug 14.

Chris P Ponting is in the MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom; Wellcome Trust Sanger Institute, Cambridge, United Kingdom

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132285PMC
http://dx.doi.org/10.7554/eLife.03058DOI Listing
August 2014

Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy.

Eur Urol 2014 Jul 14;66(1):32-9. Epub 2013 Aug 14.

Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Cancer Research UK Beatson Institute, Glasgow, UK; Cancer Research UK Beatson Institute, The Beatson Institute for Cancer Research, Glasgow, UK. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2013.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062940PMC
July 2014

8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineage.

PLoS Genet 2014 Jul 24;10(7):e1004525. Epub 2014 Jul 24.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109858PMC
July 2014

Diagnostically relevant facial gestalt information from ordinary photos.

Elife 2014 Jun 24;3:e02020. Epub 2014 Jun 24.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067075PMC
http://dx.doi.org/10.7554/eLife.02020DOI Listing
June 2014

A code for RanGDP binding in ankyrin repeats defines a nuclear import pathway.

Cell 2014 May;157(5):1130-45

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, OX3 7DQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.05.006DOI Listing
May 2014

Identification and function of long non-coding RNAs.

Essays Biochem 2013 ;54:113-26

MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1042/bse0540113DOI Listing
April 2014

Brain-expressed 3'UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs.

Front Genet 2014 26;5:41. Epub 2014 Feb 26.

Department of Physiology, Anatomy and Genetics, University of Oxford Oxford, UK ; MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford Oxford, UK.

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http://dx.doi.org/10.3389/fgene.2014.00041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935148PMC
March 2014

Sequencing depth and coverage: key considerations in genomic analyses.

Nat Rev Genet 2014 Feb;15(2):121-32

Computational Genomics Analysis and Training Programme, Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, Le Gros Clark Building, University of Oxford, Parks Road, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1038/nrg3642DOI Listing
February 2014

Mutagenesis and homologous recombination in Drosophila cell lines using CRISPR/Cas9.

Biol Open 2014 Jan 15;3(1):42-9. Epub 2014 Jan 15.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK.

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http://bio.biologists.org/cgi/doi/10.1242/bio.20137120
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http://dx.doi.org/10.1242/bio.20137120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892159PMC
January 2014

Rapid evolution of Beta-keratin genes contribute to phenotypic differences that distinguish turtles and birds from other reptiles.

Genome Biol Evol 2013 ;5(5):923-33

Department of Physiology, Anatomy and Genetics, MRC Functional Genomics Unit, University of Oxford, United Kingdom.

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https://academic.oup.com/gbe/article-lookup/doi/10.1093/gbe/
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http://dx.doi.org/10.1093/gbe/evt060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673632PMC
December 2013

Tiki, at the head of a new superfamily of enzymes.

Bioinformatics 2013 Oct 18;29(19):2371-4. Epub 2013 Jul 18.

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1093/bioinformatics/btt412DOI Listing
October 2013

Predicting long non-coding RNAs using RNA sequencing.

Methods 2013 Sep 27;63(1):50-9. Epub 2013 Mar 27.

CGAT, MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2013.03.019DOI Listing
September 2013

GAT: a simulation framework for testing the association of genomic intervals.

Bioinformatics 2013 Aug 18;29(16):2046-8. Epub 2013 Jun 18.

MRC CGAT Programme and Functional Genomics Unit, MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/bioinformatics/btt343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722528PMC
August 2013

Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors.

Proc Natl Acad Sci U S A 2013 Aug 22;110(32):13150-5. Epub 2013 Jul 22.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1307444110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740902PMC
August 2013

Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system.

Cell Rep 2013 Jul 1;4(1):220-8. Epub 2013 Jul 1.

Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3PT, UK.

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http://dx.doi.org/10.1016/j.celrep.2013.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714591PMC
July 2013

The African coelacanth genome provides insights into tetrapod evolution.

Nature 2013 Apr;496(7445):311-6

Molecular Genetics Program, Benaroya Research Institute, Seattle, Washington 98101, USA.

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http://dx.doi.org/10.1038/nature12027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633110PMC
April 2013

Cofilin-1: a modulator of anxiety in mice.

PLoS Genet 2012 4;8(10):e1002970. Epub 2012 Oct 4.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464202PMC
March 2013

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.

Elife 2013 Feb 26;2:e00348. Epub 2013 Feb 26.

Department of Biochemistry , University of Oxford , Oxford , United Kingdom ; Weatherall Institute of Molecular Medicine, University of Oxford , Oxford , United Kingdom.

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http://dx.doi.org/10.7554/eLife.00348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583005PMC
February 2013

Rapid turnover of long noncoding RNAs and the evolution of gene expression.

PLoS Genet 2012 26;8(7):e1002841. Epub 2012 Jul 26.

Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406015PMC
January 2013

Loaded dice for human genome mutation.

Authors:
Chris P Ponting

Cell 2012 Dec;151(7):1399-400

MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1016/j.cell.2012.12.002DOI Listing
December 2012

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

J Biol Chem 2012 Sep 3;287(39):32346-53. Epub 2012 Aug 3.

Medical Research Council Protein Phosphorylation Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M112.382499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463326PMC
September 2012

Brain, know thy transcriptome, know thyself.

Neuron 2012 Aug;75(4):543-5

MRC Functional Genomics Unit, University of Oxford, Department of Physiology, Anatomy, and Genetics, Oxford OX1 3PT, UK.

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http://dx.doi.org/10.1016/j.neuron.2012.08.005DOI Listing
August 2012