Chris Fegan

Chris Fegan

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Chris Fegan

Chris Fegan

Publications by authors named "Chris Fegan"

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55Publications

474Reads

Telomere length is a critical determinant for survival in multiple myeloma.

Br J Haematol 2017 07 24;178(1):94-98. Epub 2017 Mar 24.

Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.

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July 2017

Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor.

Oncotarget 2017 Feb;8(7):11414-11424

Neuro-Bio Ltd, Culham Science Centre, Abingdon, OX14 3DB, UK.

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February 2017

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Nat Commun 2017 02 6;8:14175. Epub 2017 Feb 6.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

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February 2017

Understanding cancer cell survival is key to patient survival.

Lancet Oncol 2015 Feb;16(2):122-4

Cardiff CLL Research Group, School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.

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February 2015

Telomere analysis to predict chronic lymphocytic leukemia outcome: a STELA test to change clinical practice?

Expert Rev Hematol 2014 Dec 11;7(6):701-3. Epub 2014 Oct 11.

Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.

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December 2014

CD8 T-cell recognition of a synthetic epitope formed by t-butyl modification.

Immunology 2014 Oct 5. Epub 2014 Oct 5.

Institute of Cancer and Genetics, Cardiff University, School of Medicine, Cancer and Genetics Building, Heath Park, Cardiff, U.K.

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October 2014

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia.

Blood 2014 Jun 17;123(23):3607-17. Epub 2014 Mar 17.

Cardiff Chronic Lymphocytic Leukemia Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom;

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June 2014

CD49d is the strongest flow cytometry-based predictor of overall survival in chronic lymphocytic leukemia.

J Clin Oncol 2014 Mar 10;32(9):897-904. Epub 2014 Feb 10.

Pietro Bulian, Antonella Zucchetto, and Valter Gattei, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Centro di Riferimento Oncologico, Aviano; Lilla Cro and Luca Baldini, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico and Università degli Studi, Milan; Gianluca Gaidano and Davide Rossi, Amedeo Avogadro University of Eastern Piedmont, Novara; Giovanni Del Poeta, Tor Vergata University, S. Eugenio Hospital, Rome, Italy; Tait D. Shanafelt, Mayo Research Center, Rochester, NY; Chris Fegan and Chris Pepper, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom; Holger Nückel, University of Duisburg-Essen, Essen, Germany; and Antonina V. Kurtova, Alessandra Ferrajoli, and Jan A. Burger, University of Texas MD Anderson Cancer Center, Houston, TX.

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March 2014

Apoptosis deregulation in CLL.

Adv Exp Med Biol 2013 ;792:151-71

CLL Research Group, Institute of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, Wales, CF14 4XN, UK,

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February 2014

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine.

Oncotarget 2014 Jan;5(2):375-85

Cardiff CLL Research Group, Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

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January 2014

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-κB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells.

Oncotarget 2012 May;3(5):525-34

Department of Haematology, Institute of Cancer and Genetics, Cardiff University, School of Medicine, Heath Park, Cardiff, UK.

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May 2012

A novel tumor antigen derived from enhanced degradation of bax protein in human cancers.

Cancer Res 2011 Aug 22;71(16):5435-44. Epub 2011 Jun 22.

Departments of Infection, Immunity and Biochemistry, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.

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August 2011

CLL: a supplementary question?

Blood 2011 Feb;117(5):1439-40

Cardiff University.

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February 2011

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.

Blood 2010 Sep 10;116(11):1899-907. Epub 2010 Jun 10.

Department of Pathology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

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September 2010

The NF-kappaB inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib.

Mol Cancer Ther 2010 Jun 1;9(6):1574-82. Epub 2010 Jun 1.

Department of Haematology, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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June 2010

NF-kappaB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia.

Future Oncol 2009 Sep;5(7):1027-37

School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.

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September 2009

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

J Clin Oncol 2009 Feb 5;27(5):763-9. Epub 2009 Jan 5.

Department of Haematology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

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February 2009

The role of tissue factor in patients undergoing open repair of ruptured and nonruptured abdominal aortic aneurysms.

J Vasc Surg 2007 Oct 30;46(4):682-6. Epub 2007 Aug 30.

University Department of Vascular Surgery, Heart of England National Health Service Foundation Trust, Birmingham, UK.

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October 2007

The effect of supervised exercise and cilostazol on coagulation and fibrinolysis in intermittent claudication: a randomized controlled trial.

J Vasc Surg 2007 Jan;45(1):65-70; discussion 70

University Department of Vascular Surgery, Heart of England NHS Foundation Trust, Birmingham, UK.

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January 2007

Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia.

Genes Chromosomes Cancer 2005 May;43(1):1-10

Department of Experimental Haematology, ICMS, Barts & The London, Queen Mary School of Medicine, London, United Kingdom.

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May 2005

Flavopiridol induces apoptosis in B-cell chronic lymphocytic leukaemia cells through a p38 and ERK MAP kinase-dependent mechanism.

Leuk Lymphoma 2003 Feb;44(2):337-42

Department of Haematology, Llandough Hospital, Penlan Road, Penarth, Vale of Glamorgan, CF64 2XX, UK.

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February 2003