Chris Fegan

Chris Fegan

UNVERIFIED PROFILE

Are you Chris Fegan?   Register this Author

Register author
Chris Fegan

Chris Fegan

Publications by authors named "Chris Fegan"

Are you Chris Fegan?   Register this Author

56Publications

631Reads

-Profile Views

Telomere length is a critical determinant for survival in multiple myeloma.

Br J Haematol 2017 07 24;178(1):94-98. Epub 2017 Mar 24.

Division of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.14643DOI Listing
July 2017

Telomere length is an independent prognostic marker in MDS but not in de novo AML.

Br J Haematol 2017 07 9;178(2):240-249. Epub 2017 May 9.

Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.14666DOI Listing
July 2017

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.

Nat Commun 2017 02 6;8:14175. Epub 2017 Feb 6.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms14175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5303820PMC
February 2017

Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration.

Blood 2016 07 1;128(4):563-73. Epub 2016 Jun 1.

Department of Haemato-Oncology, Division of Cancer Studies, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2016-01-683128DOI Listing
July 2016

Understanding cancer cell survival is key to patient survival.

Lancet Oncol 2015 Feb;16(2):122-4

Cardiff CLL Research Group, School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(15)70003-3DOI Listing
February 2015

Telomere analysis to predict chronic lymphocytic leukemia outcome: a STELA test to change clinical practice?

Expert Rev Hematol 2014 Dec 11;7(6):701-3. Epub 2014 Oct 11.

Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/17474086.2014.969705DOI Listing
December 2014

CD8 T-cell recognition of a synthetic epitope formed by t-butyl modification.

Immunology 2014 Oct 5. Epub 2014 Oct 5.

Institute of Cancer and Genetics, Cardiff University, School of Medicine, Cancer and Genetics Building, Heath Park, Cardiff, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imm.12398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557686PMC
October 2014

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia.

Blood 2014 Jun 17;123(23):3607-17. Epub 2014 Mar 17.

Cardiff Chronic Lymphocytic Leukemia Research Group, Institute of Cancer & Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2013-12-544569DOI Listing
June 2014

CD49d is the strongest flow cytometry-based predictor of overall survival in chronic lymphocytic leukemia.

J Clin Oncol 2014 Mar 10;32(9):897-904. Epub 2014 Feb 10.

Pietro Bulian, Antonella Zucchetto, and Valter Gattei, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Centro di Riferimento Oncologico, Aviano; Lilla Cro and Luca Baldini, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico and Università degli Studi, Milan; Gianluca Gaidano and Davide Rossi, Amedeo Avogadro University of Eastern Piedmont, Novara; Giovanni Del Poeta, Tor Vergata University, S. Eugenio Hospital, Rome, Italy; Tait D. Shanafelt, Mayo Research Center, Rochester, NY; Chris Fegan and Chris Pepper, Institute of Cancer and Genetics, Cardiff University School of Medicine, Cardiff, United Kingdom; Holger Nückel, University of Duisburg-Essen, Essen, Germany; and Antonina V. Kurtova, Alessandra Ferrajoli, and Jan A. Burger, University of Texas MD Anderson Cancer Center, Houston, TX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2013.50.8515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876311PMC
March 2014

Apoptosis deregulation in CLL.

Adv Exp Med Biol 2013 ;792:151-71

CLL Research Group, Institute of Cancer and Genetics, Cardiff University, Heath Park, Cardiff, Wales, CF14 4XN, UK,

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-4614-8051-8_7
Publisher Site
http://dx.doi.org/10.1007/978-1-4614-8051-8_7DOI Listing
February 2014

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine.

Oncotarget 2014 Jan;5(2):375-85

Cardiff CLL Research Group, Institute of Cancer and Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, UK.

View Article

Download full-text PDF

Source
http://www.oncotarget.com/fulltext/1568
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964214PMC
http://dx.doi.org/10.18632/oncotarget.1568DOI Listing
January 2014

A novel tumor antigen derived from enhanced degradation of bax protein in human cancers.

Cancer Res 2011 Aug 22;71(16):5435-44. Epub 2011 Jun 22.

Departments of Infection, Immunity and Biochemistry, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-11-0393DOI Listing
August 2011

CLL: a supplementary question?

Blood 2011 Feb;117(5):1439-40

Cardiff University.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2010-11-318451DOI Listing
February 2011

Telomere dysfunction and fusion during the progression of chronic lymphocytic leukemia: evidence for a telomere crisis.

Blood 2010 Sep 10;116(11):1899-907. Epub 2010 Jun 10.

Department of Pathology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

View Article

Download full-text PDF

Source
http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-02-27
Publisher Site
http://dx.doi.org/10.1182/blood-2010-02-272104DOI Listing
September 2010

The NF-kappaB inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib.

Mol Cancer Ther 2010 Jun 1;9(6):1574-82. Epub 2010 Jun 1.

Department of Haematology, School of Medicine, Cardiff University, Cardiff, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-10-0104DOI Listing
June 2010

NF-kappaB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia.

Future Oncol 2009 Sep;5(7):1027-37

School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon.09.72DOI Listing
September 2009

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

J Clin Oncol 2009 Feb 5;27(5):763-9. Epub 2009 Jan 5.

Department of Haematology, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2008.19.1114DOI Listing
February 2009

The role of tissue factor in patients undergoing open repair of ruptured and nonruptured abdominal aortic aneurysms.

J Vasc Surg 2007 Oct 30;46(4):682-6. Epub 2007 Aug 30.

University Department of Vascular Surgery, Heart of England National Health Service Foundation Trust, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jvs.2007.05.057DOI Listing
October 2007

The effect of supervised exercise and cilostazol on coagulation and fibrinolysis in intermittent claudication: a randomized controlled trial.

J Vasc Surg 2007 Jan;45(1):65-70; discussion 70

University Department of Vascular Surgery, Heart of England NHS Foundation Trust, Birmingham, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jvs.2006.08.084DOI Listing
January 2007

Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia.

Genes Chromosomes Cancer 2005 May;43(1):1-10

Department of Experimental Haematology, ICMS, Barts & The London, Queen Mary School of Medicine, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20159DOI Listing
May 2005

Flavopiridol induces apoptosis in B-cell chronic lymphocytic leukaemia cells through a p38 and ERK MAP kinase-dependent mechanism.

Leuk Lymphoma 2003 Feb;44(2):337-42

Department of Haematology, Llandough Hospital, Penlan Road, Penarth, Vale of Glamorgan, CF64 2XX, UK.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/full/10.1080/1042819021000029
Publisher Site
http://dx.doi.org/10.1080/1042819021000029984DOI Listing
February 2003