Chris Denning

Chris Denning

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Chris Denning

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High-Throughput Phenotyping Toolkit for Characterizing Cellular Models of Hypertrophic Cardiomyopathy In Vitro.

Methods Protoc 2019 Oct 26;2(4). Epub 2019 Oct 26.

Department of Stem Cell Biology, Centre of Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.3390/mps2040083DOI Listing
October 2019

Modeling Hypertrophic Cardiomyopathy: Mechanistic Insights and Pharmacological Intervention.

Trends Mol Med 2019 Sep 17;25(9):775-790. Epub 2019 Jul 17.

Department of Stem Cell Biology, Centre of Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.1016/j.molmed.2019.06.005DOI Listing
September 2019

Surface plasmon resonance imaging of excitable cells.

J Phys D Appl Phys 2019 Mar 4;52(10):104001. Epub 2019 Jan 4.

Department of Electrical and Electronic Engineering, University of Nottingham, Nottingham, NG7 2RD, United Kingdom.

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http://dx.doi.org/10.1088/1361-6463/aaf849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380809PMC
March 2019

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D.

Front Physiol 2019 18;10:259. Epub 2019 Mar 18.

The William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.3389/fphys.2019.00259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430739PMC
March 2019

Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits.

Stem Cell Reports 2018 11 1;11(5):1226-1243. Epub 2018 Nov 1.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183042
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http://dx.doi.org/10.1016/j.stemcr.2018.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235010PMC
November 2018

Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing.

Stem Cell Res Ther 2018 09 26;9(1):248. Epub 2018 Sep 26.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), School of Medicine, The University of Nottingham, Nottingham, NG7 2RD, UK.

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http://dx.doi.org/10.1186/s13287-018-0968-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158868PMC
September 2018

Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells.

Stem Cells Dev 2018 03 12;27(6):391-404. Epub 2018 Mar 12.

Department of Stem Cell Biology, Centre of Biomolecular Sciences, University of Nottingham , Nottingham, United Kingdom .

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http://dx.doi.org/10.1089/scd.2017.0268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882176PMC
March 2018

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.

Circ Res 2018 02 27;122(3):e5-e16. Epub 2017 Dec 27.

From the Department of Anatomy and Embryology, Leiden University Medical Center, The Netherlands (L.S., B.J.v.M., L.G.J.T., M.B., R.P.D., M.A.E.D., E.G., C.G., M.R.M.J., M.P.H.M., V.V.O., R.P., C.L.M.); Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary, and Life Science, University of Glasgow, United Kingdom (Q.L., G.L.S., F.L.B.); Hubrecht Institute - Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands (J.B., S.M.K., C.D.K.); Department of Stem Cell Biology, University of Nottingham, University Park, Nottingham, United Kingdom (C.D., D.M.); Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, Germany (T.E., A.H., I.M., U.S.); DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck (T.E., A.H., I.M., U.S.); Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, Hamburg, Germany (U.S.); Hart Long Centrum, Leiden University Medical Center, The Netherlands (E.R.H., M.R.M.J.); Department of Applied Stem Cell Technologies, University of Twente, Enschede, The Netherlands (R.P., M.C.R., C.L.M.).; Division of Heart and Lungs, Department of Medical Physiology, University Medical Center Utrecht, The Netherlands (J.B., S.M.K., C.D.K.); and Clyde Biosciences, Ltd, BioCity Scotland, United Kingdom (G.L.S., F.L.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805275PMC
February 2018

Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Stem Cells Dev 2017 12 9;26(23):1695-1705. Epub 2017 Oct 9.

1 Department of Stem Cell Biology, Centre of Biomolecular Sciences, University of Nottingham , Nottingham, United Kingdom .

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http://dx.doi.org/10.1089/scd.2017.0172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706629PMC
December 2017

Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion.

Biomater Sci 2016 Aug;4(9):1381-91

Laboratory of Biophysics and Surface Analysis, School of Pharmacy, University of Nottingham, Nottingham, NG7 2RD, UK. morgan.alexander.nottingham.ac.uk.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5038343PMC
http://dx.doi.org/10.1039/c6bm00214eDOI Listing
August 2016

Can Human Pluripotent Stem Cell-Derived Cardiomyocytes Advance Understanding of Muscular Dystrophies?

J Neuromuscul Dis 2016 08;3(3):309-332

Department of Stem Cell Biology, Centre for Biomolecular Sciences, University of Nottingham, UK.

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http://dx.doi.org/10.3233/JND-150133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123622PMC
August 2016

Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes.

Stem Cells Dev 2016 Mar 23;25(6):439-52. Epub 2016 Feb 23.

1 Division of Cancer and Stem Cells, School of Medicine, Wolfson Centre for Stem Cells, Tissue Engineering & Modelling, University of Nottingham , Nottingham, United Kingdom .

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http://dx.doi.org/10.1089/scd.2015.0253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790208PMC
March 2016

Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides.

Proc Natl Acad Sci U S A 2016 Jan 5;113(3):E291-9. Epub 2016 Jan 5.

School of Pharmacy, Wolfson Centre for Stem Cells, Tissue Engineering, and Modelling, Centre of Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1518634113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725514PMC
January 2016

Scaling human pluripotent stem cell expansion and differentiation: are cell factories becoming a reality?

Regen Med 2015 Nov 6;10(8):925-30. Epub 2015 Nov 6.

Wolfson Centre for Stem Cells, Tissue Engineering & Modelling Centre for Biomolecular Sciences, University of Nottingham, Nottingham, NG7 2RD, UK.

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http://dx.doi.org/10.2217/rme.15.65DOI Listing
November 2015

Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy.

Dis Model Mech 2015 May 19;8(5):457-66. Epub 2015 Mar 19.

Department of Developmental Biology, University of Pittsburgh School of Medicine, 530 45th Street, 8117 Rangos Research Center, Pittsburgh, PA 15201, USA

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http://dmm.biologists.org/cgi/doi/10.1242/dmm.019505
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http://dx.doi.org/10.1242/dmm.019505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415895PMC
May 2015

Materials for stem cell factories of the future.

Nat Mater 2014 Jun;13(6):570-9

Laboratory of Biophysics and Surface Analysis, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, UK.

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https://www.nottingham.ac.uk/pharmacy/documents/documents/ma
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http://www.nature.com/doifinder/10.1038/nmat3972
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http://dx.doi.org/10.1038/nmat3972DOI Listing
June 2014

Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes.

Eur Heart J 2014 Apr 6;35(16):1078-87. Epub 2013 Mar 6.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.1093/eurheartj/eht067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992427PMC
April 2014

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation.

Proc Natl Acad Sci U S A 2014 Apr 27;111(15):5580-5. Epub 2014 Mar 27.

Wolfson Centre for Stem Cells, Tissue Engineering, and Modelling, Centre of Biomolecular Sciences, School of Pharmacy, Medical Engineering Unit, School of Mechanical, Materials and Manufacturing Engineering, Nottingham Nanotechnology and Nanoscience Centre, Faculty of Engineering, and School of Medicine, University of Nottingham, Nottingham NG7 2RD, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1319685111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992688PMC
April 2014

Exon skipping and gene transfer restore dystrophin expression in human induced pluripotent stem cells-cardiomyocytes harboring DMD mutations.

Stem Cells Dev 2013 Oct 5;22(20):2714-24. Epub 2013 Jul 5.

1 Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), Centre for Biomolecular Sciences, University of Nottingham , Nottingham, United Kingdom .

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http://dx.doi.org/10.1089/scd.2013.0135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787465PMC
October 2013

Non-invasive label-free monitoring the cardiac differentiation of human embryonic stem cells in-vitro by Raman spectroscopy.

Biochim Biophys Acta 2013 Jun 9;1830(6):3517-24. Epub 2013 Feb 9.

School of Physics and Astronomy, University of Nottingham, Nottingham, NG7 2RD, UK.

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http://dx.doi.org/10.1016/j.bbagen.2013.01.030DOI Listing
June 2013

Current status of drug screening and disease modelling in human pluripotent stem cells.

Bioessays 2013 Mar 8;35(3):281-98. Epub 2012 Aug 8.

Department of Stem Cells, Tissue Engineering & Modelling, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1002/bies.201200053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597971PMC
March 2013

Rapid micropatterning of cell lines and human pluripotent stem cells on elastomeric membranes.

Biotechnol Bioeng 2012 Oct 24;109(10):2630-41. Epub 2012 Apr 24.

Wolfson Centre for Stem Cells, Tissue Engineering, and Modelling (STEM), Centre of Biomolecular Sciences, School of Pharmacy, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

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http://dx.doi.org/10.1002/bit.24529DOI Listing
October 2012

In vitro uses of human pluripotent stem cell-derived cardiomyocytes.

J Cardiovasc Transl Res 2012 Oct 26;5(5):581-92. Epub 2012 May 26.

Wolfson Centre for Stem Cells, Tissue Engineering & Modelling, University of Nottingham, University Park, Nottingham, UK.

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http://link.springer.com/content/pdf/10.1007/s12265-012-9376
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http://link.springer.com/10.1007/s12265-012-9376-5
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http://dx.doi.org/10.1007/s12265-012-9376-5DOI Listing
October 2012

5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.

Epigenetics 2012 Apr 1;7(4):383-9. Epub 2012 Apr 1.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), School of Clinical Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.4161/epi.19375DOI Listing
April 2012

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.

Authors:
Katherine Amps Peter W Andrews George Anyfantis Lyle Armstrong Stuart Avery Hossein Baharvand Julie Baker Duncan Baker Maria B Munoz Stephen Beil Nissim Benvenisty Dalit Ben-Yosef Juan-Carlos Biancotti Alexis Bosman Romulo Martin Brena Daniel Brison Gunilla Caisander María V Camarasa Jieming Chen Eric Chiao Young Min Choi Andre B H Choo Daniel Collins Alan Colman Jeremy M Crook George Q Daley Anne Dalton Paul A De Sousa Chris Denning Janet Downie Petr Dvorak Karen D Montgomery Anis Feki Angela Ford Victoria Fox Ana M Fraga Tzvia Frumkin Lin Ge Paul J Gokhale Tamar Golan-Lev Hamid Gourabi Michal Gropp Guangxiu Lu Ales Hampl Katie Harron Lyn Healy Wishva Herath Frida Holm Outi Hovatta Johan Hyllner Maneesha S Inamdar Astrid Kresentia Irwanto Tetsuya Ishii Marisa Jaconi Ying Jin Susan Kimber Sergey Kiselev Barbara B Knowles Oded Kopper Valeri Kukharenko Anver Kuliev Maria A Lagarkova Peter W Laird Majlinda Lako Andrew L Laslett Neta Lavon Dong Ryul Lee Jeoung Eun Lee Chunliang Li Linda S Lim Tenneille E Ludwig Yu Ma Edna Maltby Ileana Mateizel Yoav Mayshar Maria Mileikovsky Stephen L Minger Takamichi Miyazaki Shin Yong Moon Harry Moore Christine Mummery Andras Nagy Norio Nakatsuji Kavita Narwani Steve K W Oh Sun Kyung Oh Cia Olson Timo Otonkoski Fei Pan In-Hyun Park Steve Pells Martin F Pera Lygia V Pereira Ouyang Qi Grace Selva Raj Benjamin Reubinoff Alan Robins Paul Robson Janet Rossant Ghasem H Salekdeh Thomas C Schulz Karen Sermon Jameelah Sheik Mohamed Hui Shen Eric Sherrer Kuldip Sidhu Shirani Sivarajah Heli Skottman Claudia Spits Glyn N Stacey Raimund Strehl Nick Strelchenko Hirofumi Suemori Bowen Sun Riitta Suuronen Kazutoshi Takahashi Timo Tuuri Parvathy Venu Yuri Verlinsky Dorien Ward-van Oostwaard Daniel J Weisenberger Yue Wu Shinya Yamanaka Lorraine Young Qi Zhou

Nat Biotechnol 2011 Nov 27;29(12):1132-44. Epub 2011 Nov 27.

Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK.

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http://www.nature.com/articles/nbt.2051
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http://dx.doi.org/10.1038/nbt.2051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454460PMC
November 2011

Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network.

Mol Ther 2011 Sep 21;19(9):1695-703. Epub 2011 Jun 21.

School of Pharmacy, Wolfson Centre for Stem Cells, Tissue Engineering, and Modelling, Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1038/mt.2011.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182351PMC
September 2011

Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection.

Nat Protoc 2011 Jun 5;6(6):701-14. Epub 2011 May 5.

Wolfson Centre for Stem Cells, Tissue Engineering & Modelling, Centre for Biomolecular Sciences, University of Nottingham, UK.

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http://dx.doi.org/10.1038/nprot.2011.320DOI Listing
June 2011

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation.

Eur Heart J 2011 Apr 2;32(8):952-62. Epub 2011 Mar 2.

Wolfson Centre for Stem Cells, Tissue Engineering & Modelling, University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.1093/eurheartj/ehr073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076668PMC
April 2011

Toward label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells.

J Biomed Opt 2011 Apr;16(4):045002

University of Nottingham, School of Physics and Astronomy, Nottingham NG7 2RD, United Kingdom.

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http://dx.doi.org/10.1117/1.3570302DOI Listing
April 2011

Two new protocols to enhance the production and isolation of human induced pluripotent stem cell lines.

Stem Cell Res 2011 Mar 20;6(2):158-67. Epub 2010 Nov 20.

Wolfson Centre for Stem Cells, Tissue Engineering & Modelling, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.

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http://dx.doi.org/10.1016/j.scr.2010.10.002DOI Listing
March 2011

Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening.

Biochem Soc Trans 2010 Aug;38(4):1037-45

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling, Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, UK.

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http://dx.doi.org/10.1042/BST0381037DOI Listing
August 2010

Derivation and characterisation of the human embryonic stem cell lines, NOTT1 and NOTT2.

In Vitro Cell Dev Biol Anim 2010 Apr 23;46(3-4):367-75. Epub 2010 Feb 23.

NURTURE, Queen's Medical Centre, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1007/s11626-010-9290-6DOI Listing
April 2010

Genetic manipulation of human embryonic stem cells in serum and feeder-free media.

Methods Mol Biol 2010 ;584:413-23

Department of Anatomy & Embryology, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/978-1-60761-369-5_22DOI Listing
February 2010

Bioluminescence imaging of human embryonic stem cells transplanted in vivo in murine and chick models.

Cloning Stem Cells 2009 Jun;11(2):259-67

Division of Human Development, University of Nottingham , Queens Medical Centre, Nottingham, United Kingdom .

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http://www.liebertpub.com/doi/10.1089/clo.2008.0056
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http://dx.doi.org/10.1089/clo.2008.0056DOI Listing
June 2009

Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification.

Nat Protoc 2008 ;3(9):1435-43

Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2008.140DOI Listing
December 2008

Improved genetic manipulation of human embryonic stem cells.

Nat Methods 2008 May 6;5(5):389-92. Epub 2008 Apr 6.

Hubrecht Institute, Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nmeth.1200DOI Listing
May 2008

Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines.

Genome Res 2007 Dec 7;17(12):1731-42. Epub 2007 Nov 7.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), University of Nottingham, Centre for Biomolecular Sciences, Nottingham NG7 2RD, United Kingdom.

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http://dx.doi.org/10.1101/gr.6609207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099582PMC
December 2007

Gene-specific vulnerability to imprinting variability in human embryonic stem cell lines.

Genome Res 2007 Dec 7;17(12):1731-42. Epub 2007 Nov 7.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), University of Nottingham, Centre for Biomolecular Sciences, Nottingham NG7 2RD, United Kingdom.

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http://dx.doi.org/10.1101/gr.6609207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099582PMC
December 2007

Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome.

Hum Mol Genet 2007 May 4;16(10):1253-68. Epub 2007 Apr 4.

Division of Obstetrics and Gynaecology and Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1093/hmg/ddm074DOI Listing
May 2007

Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability.

Stem Cells 2007 Apr 21;25(4):929-38. Epub 2006 Dec 21.

Wolfson Centre for Stem Cells, Tissue Engineering and Modelling, School of Human Development, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom.

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http://dx.doi.org/10.1634/stemcells.2006-0598DOI Listing
April 2007

Genetic modification of sheep by nuclear transfer with gene-targeted somatic cells.

Methods Mol Biol 2006 ;348:199-212

Roslin Institute, Roslin, Midlothian, UK.

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http://dx.doi.org/10.1007/978-1-59745-154-3_13DOI Listing
December 2006

The patentability of human embryonic stem cells in Europe.

Nat Biotechnol 2006 Jun;24(6):653-5

University of Nottingham, School of Law, Nottingham NG7 2RD, UK.

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http://www.nature.com/articles/nbt0606-653
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http://dx.doi.org/10.1038/nbt0606-653DOI Listing
June 2006

Molecular and phenotypic analyses of human embryonic stem cell-derived cardiomyocytes: opportunities and challenges for clinical translation.

Thromb Haemost 2005 Oct;94(4):728-37

Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham, UK.

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http://dx.doi.org/10.1160/TH05-04-0268DOI Listing
October 2005

Human embryonic stem cells as a model for nutritional programming: an evaluation.

Reprod Toxicol 2005 Sep-Oct;20(3):353-67

University of Nottingham, Obstetrics and Gynaecology, D Floor East Block, Queens Medical, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1016/j.reprotox.2005.04.010DOI Listing
September 2005

Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction?

Reprod Biomed Online 2005 Jun;10(6):755-66

Division of Obstetrics and Gynaecology, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1016/s1472-6483(10)61120-0DOI Listing
June 2005

Stem-cell consequences of embryo epigenetic defects.

Lancet 2004 Jul 10-16;364(9429):206-8

Division of Obstetrics and Gynaecology, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.

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http://dx.doi.org/10.1016/S0140-6736(04)16636-1DOI Listing
July 2004

New frontiers in gene targeting and cloning: success, application and challenges in domestic animals and human embryonic stem cells.

Reproduction 2003 Jul;126(1):1-11

University of Nottingham, Division of Animal Physiology, School of Biosciences, Sutton Bonington LE12 5RD, UK.

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http://dx.doi.org/10.1530/rep.0.1260001DOI Listing
July 2003

Proliferative lifespan is conserved after nuclear transfer.

Nat Cell Biol 2003 Jun;5(6):535-8

Department of Gene Expression and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK.

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http://dx.doi.org/10.1038/ncb992DOI Listing
June 2003