Chris Cheadle

Chris Cheadle

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Chris Cheadle

Publications by authors named "Chris Cheadle"

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Comprehensive literature data-mining analysis reveals a broad genetic network functionally associated with autism spectrum disorder.

Int J Mol Med 2018 Nov 28;42(5):2353-2362. Epub 2018 Aug 28.

Department of Genomics Research, Elsevier R&D Solutions, Elsevier Inc., Rockville, MD 20852, USA.

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http://dx.doi.org/10.3892/ijmm.2018.3845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192781PMC
November 2018

Advanced literature analysis in a Big Data world.

Ann N Y Acad Sci 2017 01 10;1387(1):25-33. Epub 2016 Nov 10.

Department of Genomics Research, R&D Solutions, Rockville, Maryland.

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http://dx.doi.org/10.1111/nyas.13270DOI Listing
January 2017

Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data.

Mediators Inflamm 2015 30;2015:984825. Epub 2015 Apr 30.

Division of Allergy & Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1155/2015/984825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4430672PMC
May 2016

Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis.

Hum Mol Genet 2015 Aug 1;24(16):4615-24. Epub 2015 Jun 1.

Division of Allergy and Clinical Immunology, the Johns Hopkins School of Medicine, Baltimore, MD 21224, USA and

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http://dx.doi.org/10.1093/hmg/ddv192DOI Listing
August 2015

RAP-011, an activin receptor ligand trap, increases hemoglobin concentration in hepcidin transgenic mice.

Am J Hematol 2015 Jan 25;90(1):8-14. Epub 2014 Oct 25.

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/ajh.23856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276439PMC
January 2015

Hypoxia-induced mitogenic factor (FIZZ1/RELMα) induces endothelial cell apoptosis and subsequent interleukin-4-dependent pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2014 Jun 2;306(12):L1090-103. Epub 2014 May 2.

Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland;

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http://dx.doi.org/10.1152/ajplung.00279.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060011PMC
June 2014

Hepcidin-dependent and hepcidin-independent regulation of erythropoiesis in a mouse model of anemia of chronic inflammation.

Am J Hematol 2014 May 24;89(5):470-9. Epub 2014 Feb 24.

Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/ajh.23670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200395PMC
May 2014

Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases.

Proc Natl Acad Sci U S A 2012 Oct 8;109(43):17609-14. Epub 2012 Oct 8.

Division of Rheumatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1209724109
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http://dx.doi.org/10.1073/pnas.1209724109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491524PMC
October 2012

Effect of luteal-phase support on endometrial microRNA expression following controlled ovarian stimulation.

Reprod Biol Endocrinol 2012 Sep 6;10:72. Epub 2012 Sep 6.

Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Lutherville, MD, USA.

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http://rbej.biomedcentral.com/articles/10.1186/1477-7827-10-
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http://dx.doi.org/10.1186/1477-7827-10-72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462109PMC
September 2012

Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations.

J Clin Endocrinol Metab 2012 Apr 18;97(4):E687-93. Epub 2012 Jan 18.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Building 10, CRC, Room 1-3330, 10 Center Drive, MSC1103, Bethesda, Maryland 20892, USA.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2011-3000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319183PMC
April 2012

Array-based nuclear run-on analysis.

Methods Mol Biol 2012 ;809:505-17

Lowe Family Genomics Core, Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-61779-376-9_33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504798PMC
March 2012

Transcriptional analysis of infiltrating T cells in kidney ischemia-reperfusion injury reveals a pathophysiological role for CCR5.

Am J Physiol Renal Physiol 2012 Mar 7;302(6):F762-73. Epub 2011 Dec 7.

Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Ross Bldg., Rm. 965, 720 Rutland Ave., Baltimore, MD 21205, USA.

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http://www.physiology.org/doi/10.1152/ajprenal.00335.2011
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http://dx.doi.org/10.1152/ajprenal.00335.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311318PMC
March 2012

Effects of anti-adhesive therapy on kidney biomarkers of ischemia reperfusion injury in human deceased donor kidney allografts.

Clin Transplant 2011 Sep-Oct;25(5):766-75. Epub 2010 Nov 28.

Lowe Family Genomics Core, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/j.1399-0012.2010.01365.xDOI Listing
February 2012

Gene expression pathways of high grade localized prostate cancer.

Prostate 2011 Oct 25;71(14):1568-77. Epub 2011 Feb 25.

Department of Urology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.21373DOI Listing
October 2011

Pulmonary endothelial cell activation during experimental acute kidney injury.

Shock 2011 Aug;36(2):170-6

Departments of Anesthesia and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/SHK.0b013e3182169c76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139735PMC
August 2011

Integrated genomic analysis of nodular tissue in macronodular adrenocortical hyperplasia: progression of tumorigenesis in a disorder associated with multiple benign lesions.

J Clin Endocrinol Metab 2011 Apr 20;96(4):E728-38. Epub 2011 Jan 20.

Section on Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2010-2420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070257PMC
April 2011

Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium.

J Immunol 2011 Feb 10;186(4):2482-94. Epub 2011 Jan 10.

Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.4049/jimmunol.0903634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872785PMC
February 2011

Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors.

Hum Mol Genet 2011 Jan 11;20(1):165-75. Epub 2010 Oct 11.

PDEGEN, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/ddq455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000682PMC
January 2011

Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) increases lung inflammation and activates pulmonary microvascular endothelial cells via an IL-4-dependent mechanism.

J Immunol 2010 Nov 1;185(9):5539-48. Epub 2010 Oct 1.

Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.4049/jimmunol.0904021DOI Listing
November 2010

Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition.

Am J Physiol Renal Physiol 2010 Jun 24;298(6):F1472-83. Epub 2010 Feb 24.

Nephrology Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://ajprenal.physiology.org/content/ajprenal/early/2010/0
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http://ajprenal.physiology.org/cgi/doi/10.1152/ajprenal.0061
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http://dx.doi.org/10.1152/ajprenal.00619.2009DOI Listing
June 2010

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling.

Hum Mol Genet 2010 Apr 15;19(8):1387-98. Epub 2010 Jan 15.

Section on Endocrinology and Genetics, Program on Developmental Endocrinology and Genetics, Eunice KennedyShriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/hmg/ddq014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846157PMC
April 2010

Time-dependent c-Myc transactomes mapped by Array-based nuclear run-on reveal transcriptional modules in human B cells.

PLoS One 2010 Mar 15;5(3):e9691. Epub 2010 Mar 15.

Lowe Family Genomics Core, Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009691PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837740PMC
March 2010

Vaccinia virus-specific molecular signature in atopic dermatitis skin.

J Allergy Clin Immunol 2010 Jan;125(1):153-159.e28

Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.jaci.2009.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814071PMC
January 2010

GSMA: Gene Set Matrix Analysis, An Automated Method for Rapid Hypothesis Testing of Gene Expression Data.

Bioinform Biol Insights 2009 Nov 24;1:49-62. Epub 2009 Nov 24.

Genomics Core, Division of Allergy and Clinical Immunology, School of Medicine, Johns Hopkins University, 5200 Eastern Avenue, Baltimore, MD 21224.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789691PMC
November 2009

Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes.

Kidney Int 2009 Mar 17;75(5):526-35. Epub 2008 Dec 17.

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ki.2008.602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676145PMC
March 2009

Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis.

Invest Ophthalmol Vis Sci 2008 May 15;49(5):1957-70. Epub 2008 Feb 15.

Laboratory of Immunology, National Eye Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1167/iovs.07-1295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2547352PMC
May 2008

The local and systemic inflammatory transcriptome after acute kidney injury.

J Am Soc Nephrol 2008 Mar 30;19(3):547-58. Epub 2008 Jan 30.

Division of Allergy and Clinical Immunology, 5501 Hopkins Bayview Circle, JHAAC 3A.62, Baltimore, Maryland, 21224, USA.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2007040469
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http://dx.doi.org/10.1681/ASN.2007040469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391061PMC
March 2008

Ischemic acute kidney injury induces a distant organ functional and genomic response distinguishable from bilateral nephrectomy.

Am J Physiol Renal Physiol 2007 Jul 27;293(1):F30-40. Epub 2007 Feb 27.

Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://www.physiology.org/doi/10.1152/ajprenal.00023.2007
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http://dx.doi.org/10.1152/ajprenal.00023.2007DOI Listing
July 2007

TLR2 and TLR4 as Potential Biomarkers of Environmental Particulate Matter Exposed Human Myeloid Dendritic Cells.

Biomark Insights 2007 May 30;2:226-40. Epub 2007 May 30.

University of Rochester School of Medicine and Dentistry, Division of Pulmonary and Critical Care Medicine, Rochester, New York, U.S.A.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717830PMC
May 2007

A rapid method for microarray cross platform comparisons using gene expression signatures.

Mol Cell Probes 2007 Feb 10;21(1):35-46. Epub 2006 Aug 10.

Genomics Core, Division of Allergy and Clinical Immunology, School of Medicine, Johns Hopkins University, Mason Lord Bldg., Center Tower, Rm. 664, 5200 Eastern Avenue, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.mcp.2006.07.004DOI Listing
February 2007

Stability regulation of mRNA and the control of gene expression.

Ann N Y Acad Sci 2005 Nov;1058:196-204

Cellular Biochemistry Section, Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1196/annals.1359.026DOI Listing
November 2005

Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability.

BMC Genomics 2005 May 20;6:75. Epub 2005 May 20.

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-6-75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156890PMC
May 2005

Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion.

Oncogene 2004 Nov;23(54):8847-56

Cellular Biochemistry Section, Basic Research Laboratory, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1750, USA.

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http://dx.doi.org/10.1038/sj.onc.1208165DOI Listing
November 2004

Application of z-score transformation to Affymetrix data.

Appl Bioinformatics 2003 ;2(4):209-17

Cellular Biochemistry Section, Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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June 2004

DSCR1(Adapt78) modulates expression of SOD1.

FASEB J 2004 Jan;18(1):62-9

Ethel Percy Andrus Gerontology Center, University of Southern California, 3715 McClintock Avenue, Los Angeles, CA 90089-0191, USA.

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http://dx.doi.org/10.1096/fj.03-0451comDOI Listing
January 2004

PubMatrix: a tool for multiplex literature mining.

BMC Bioinformatics 2003 Dec 10;4:61. Epub 2003 Dec 10.

Gene Expression and Genomics Unit, National Institutes of Health, Baltimore, MD, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/1471-2105-4-61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC317283PMC
December 2003

Analysis of microarray data using Z score transformation.

J Mol Diagn 2003 May;5(2):73-81

DNA Array Unit, Research Resources Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21221, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1907322PMC
http://dx.doi.org/10.1016/S1525-1578(10)60455-2DOI Listing
May 2003

von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays.

Mol Cell Biol 2003 Apr;23(7):2316-28

Laboratory of Cellular and Molecular Biology, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150743PMC
http://dx.doi.org/10.1128/mcb.23.7.2316-2328.2003DOI Listing
April 2003

A genomic-scale view of the cAMP response element-enhancer decoy: a tumor target-based genetic tool.

Proc Natl Acad Sci U S A 2002 Nov 18;99(24):15626-31. Epub 2002 Nov 18.

Cellular Biochemistry Section, Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://www.pnas.org/content/99/24/15626.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.242617799
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http://dx.doi.org/10.1073/pnas.242617799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC137767PMC
November 2002

AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression.

Exp Neurol 2002 Jun;175(2):318-37

Cellular Neurobiology Research Branch, National Institute on Drug Abuse, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1006/exnr.2002.7898DOI Listing
June 2002

Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy.

Ann N Y Acad Sci 2002 Jun;968:22-36

Cellular Biochemistry Section, BRL, CCR, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1750, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2002.tb04324.xDOI Listing
June 2002

Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer.

Cancer Res 2002 May;62(10):2923-8

Laboratory of Cellular and Molecular Biology, Gerontology Research Center, National Institute on Aging/NIH, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA.

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May 2002