Publications by authors named "Chris Brightling"

70Publications

Letter from the UK.

Respirology 2020 12 19;25(12):1323-1324. Epub 2020 Oct 19.

Institute for Lung Health, NIHR Respiratory BRC, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK.

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December 2020

Guidance production before evidence generation for critical issues: the example of COVID-19.

Eur Respir Rev 2020 Sep 5;29(157). Epub 2020 Oct 5.

Lady Davis Carmel Medical Center, Pulmonary Division, Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.

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September 2020

Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.

Authors:
Derek C Angus Lennie Derde Farah Al-Beidh Djillali Annane Yaseen Arabi Abigail Beane Wilma van Bentum-Puijk Lindsay Berry Zahra Bhimani Marc Bonten Charlotte Bradbury Frank Brunkhorst Meredith Buxton Adrian Buzgau Allen C Cheng Menno de Jong Michelle Detry Lise Estcourt Mark Fitzgerald Herman Goossens Cameron Green Rashan Haniffa Alisa M Higgins Christopher Horvat Sebastiaan J Hullegie Peter Kruger Francois Lamontagne Patrick R Lawler Kelsey Linstrum Edward Litton Elizabeth Lorenzi John Marshall Daniel McAuley Anna McGlothin Shay McGuinness Bryan McVerry Stephanie Montgomery Paul Mouncey Srinivas Murthy Alistair Nichol Rachael Parke Jane Parker Kathryn Rowan Ashish Sanil Marlene Santos Christina Saunders Christopher Seymour Anne Turner Frank van de Veerdonk Balasubramanian Venkatesh Ryan Zarychanski Scott Berry Roger J Lewis Colin McArthur Steven A Webb Anthony C Gordon Farah Al-Beidh Derek Angus Djillali Annane Yaseen Arabi Wilma van Bentum-Puijk Scott Berry Abigail Beane Zahra Bhimani Marc Bonten Charlotte Bradbury Frank Brunkhorst Meredith Buxton Allen Cheng Menno De Jong Lennie Derde Lise Estcourt Herman Goossens Anthony Gordon Cameron Green Rashan Haniffa Francois Lamontagne Patrick Lawler Edward Litton John Marshall Colin McArthur Daniel McAuley Shay McGuinness Bryan McVerry Stephanie Montgomery Paul Mouncey Srinivas Murthy Alistair Nichol Rachael Parke Kathryn Rowan Christopher Seymour Anne Turner Frank van de Veerdonk Steve Webb Ryan Zarychanski Lewis Campbell Andrew Forbes David Gattas Stephane Heritier Lisa Higgins Peter Kruger Sandra Peake Jeffrey Presneill Ian Seppelt Tony Trapani Paul Young Sean Bagshaw Nick Daneman Niall Ferguson Cheryl Misak Marlene Santos Sebastiaan Hullegie Mathias Pletz Gernot Rohde Kathy Rowan Brian Alexander Kim Basile Timothy Girard Christopher Horvat David Huang Kelsey Linstrum Jennifer Vates Richard Beasley Robert Fowler Steve McGloughlin Susan Morpeth David Paterson Bala Venkatesh Tim Uyeki Kenneth Baillie Eamon Duffy Rob Fowler Thomas Hills Katrina Orr Asad Patanwala Steve Tong Mihai Netea Shilesh Bihari Marc Carrier Dean Fergusson Ewan Goligher Ghady Haidar Beverley Hunt Anand Kumar Mike Laffan Patrick Lawless Sylvain Lother Peter McCallum Saskia Middeldopr Zoe McQuilten Matthew Neal John Pasi Roger Schutgens Simon Stanworth Alexis Turgeon Alexandra Weissman Neill Adhikari Matthew Anstey Emily Brant Angelique de Man Francois Lamonagne Marie-Helene Masse Andrew Udy Donald Arnold Phillipe Begin Richard Charlewood Michael Chasse Mark Coyne Jamie Cooper James Daly Iain Gosbell Heli Harvala-Simmonds Tom Hills Sheila MacLennan David Menon John McDyer Nicole Pridee David Roberts Manu Shankar-Hari Helen Thomas Alan Tinmouth Darrell Triulzi Tim Walsh Erica Wood Carolyn Calfee Cecilia O’Kane Murali Shyamsundar Pratik Sinha Taylor Thompson Ian Young Shailesh Bihari Carol Hodgson John Laffey Danny McAuley Neil Orford Ary Neto Michelle Detry Mark Fitzgerald Roger Lewis Anna McGlothlin Ashish Sanil Christina Saunders Lindsay Berry Elizabeth Lorenzi Eliza Miller Vanessa Singh Claire Zammit Wilma van Bentum Puijk Wietske Bouwman Yara Mangindaan Lorraine Parker Svenja Peters Ilse Rietveld Kik Raymakers Radhika Ganpat Nicole Brillinger Rene Markgraf Kate Ainscough Kathy Brickell Aisha Anjum Janis-Best Lane Alvin Richards-Belle Michelle Saull Daisy Wiley Julian Bion Jason Connor Simon Gates Victoria Manax Tom van der Poll John Reynolds Marloes van Beurden Evelien Effelaar Joost Schotsman Craig Boyd Cain Harland Audrey Shearer Jess Wren Giles Clermont William Garrard Kyle Kalchthaler Andrew King Daniel Ricketts Salim Malakoutis Oscar Marroquin Edvin Music Kevin Quinn Heidi Cate Karen Pearson Joanne Collins Jane Hanson Penny Williams Shane Jackson Adeeba Asghar Sarah Dyas Mihaela Sutu Sheenagh Murphy Dawn Williamson Nhlanhla Mguni Alison Potter David Porter Jayne Goodwin Clare Rook Susie Harrison Hannah Williams Hilary Campbell Kaatje Lomme James Williamson Jonathan Sheffield Willian van’t Hoff Phobe McCracken Meredith Young Jasmin Board Emma Mart Cameron Knott Julie Smith Catherine Boschert Julia Affleck Mahesh Ramanan Ramsy D’Souza Kelsey Pateman Arif Shakih Winston Cheung Mark Kol Helen Wong Asim Shah Atul Wagh Joanne Simpson Graeme Duke Peter Chan Brittney Cartner Stephanie Hunter Russell Laver Tapaswi Shrestha Adrian Regli Annamaria Pellicano James McCullough Mandy Tallott Nikhil Kumar Rakshit Panwar Gail Brinkerhoff Cassandra Koppen Federica Cazzola Matthew Brain Sarah Mineall Roy Fischer Vishwanath Biradar Natalie Soar Hayden White Kristen Estensen Lynette Morrison Joanne Smith Melanie Cooper Monash Health Yahya Shehabi Wisam Al-Bassam Amanda Hulley Christina Whitehead Julie Lowrey Rebecca Gresha James Walsham Jason Meyer Meg Harward Ellen Venz Patricia Williams Catherine Kurenda Kirsy Smith Margaret Smith Rebecca Garcia Deborah Barge Deborah Byrne Kathleen Byrne Alana Driscoll Louise Fortune Pierre Janin Elizabeth Yarad Naomi Hammond Frances Bass Angela Ashelford Sharon Waterson Steve Wedd Robert McNamara Heidi Buhr Jennifer Coles Sacha Schweikert Bradley Wibrow Rashmi Rauniyar Erina Myers Ed Fysh Ashlish Dawda Bhaumik Mevavala Ed Litton Janet Ferrier Priya Nair Hergen Buscher Claire Reynolds John Santamaria Leanne Barbazza Jennifer Homes Roger Smith Lauren Murray Jane Brailsford Loretta Forbes Teena Maguire Vasanth Mariappa Judith Smith Scott Simpson Matthew Maiden Allsion Bone Michelle Horton Tania Salerno Martin Sterba Wenli Geng Pieter Depuydt Jan De Waele Liesbet De Bus Jan Fierens Stephanie Bracke Brenda Reeve William Dechert Michaël Chassé François Martin Carrier Dounia Boumahni Fatna Benettaib Ali Ghamraoui David Bellemare Ève Cloutier Charles Francoeur François Lamontagne Frédérick D’Aragon Elaine Carbonneau Julie Leblond Gloria Vazquez-Grande Nicole Marten Maggie Wilson Martin Albert Karim Serri Alexandros Cavayas Mathilde Duplaix Virginie Williams Bram Rochwerg Tim Karachi Simon Oczkowski John Centofanti Tina Millen Erick Duan Jennifer Tsang Lisa Patterson Shane English Irene Watpool Rebecca Porteous Sydney Miezitis Lauralyn McIntyre Laurent Brochard Karen Burns Gyan Sandhu Imrana Khalid Alexandra Binnie Elizabeth Powell Alexandra McMillan Tracy Luk Noah Aref Zdravko Andric Sabina Cviljevic Renata Đimoti Marija Zapalac Gordan Mirković Bruno Baršić Marko Kutleša Viktor Kotarski Ana Vujaklija Brajković Jakša Babel Helena Sever Lidija Dragija Ira Kušan Suvi Vaara Leena Pettilä Jonna Heinonen Anne Kuitunen Sari Karlsson Annukka Vahtera Heikki Kiiski Sanna Ristimäki Amine Azaiz Cyril Charron Mathieu Godement Guillaume Geri Antoine Vieillard-Baron Franck Pourcine Mehran Monchi David Luis Romain Mercier Anne Sagnier Nathalie Verrier Cecile Caplin Shidasp Siami Christelle Aparicio Sarah Vautier Asma Jeblaoui Muriel Fartoukh Laura Courtin Vincent Labbe Cécile Leparco Grégoire Muller Mai-Anh Nay Toufik Kamel Dalila Benzekri Sophie Jacquier Emmanuelle Mercier Delphine Chartier Charlotte Salmon PierreFrançois Dequin Francis Schneider Guillaume Morel Sylvie L’Hotellier Julio Badie Fernando Daniel Berdaguer Sylvain Malfroy Chaouki Mezher Charlotte Bourgoin Bruno Megarbane Sebastian Voicu Nicolas Deye Isabelle Malissin Laetitia Sutterlin Christophe Guitton Cédric Darreau Mickaël Landais Nicolas Chudeau Alain Robert Pierre Moine Nicholas Heming Virginie Maxime Isabelle Bossard Tiphaine Barbarin Nicholier Gwenhael Colin Vanessa Zinzoni Natacham Maquigneau André Finn Gabriele Kreß Uwe Hoff Carl Friedrich Hinrichs Jens Nee Mathias Pletz Stefan Hagel Juliane Ankert Steffi Kolanos Frank Bloos Sirak Petros Bastian Pasieka Kevin Kunz Peter Appelt Bianka Schütze Stefan Kluge Axel Nierhaus Dominik Jarczak Kevin Roedl Dirk Weismann Anna Frey Vivantes Klinikum Neukölln Lorenz Reill Michael Distler Astrid Maselli János Bélteczki István Magyar Ágnes Fazekas Sándor Kovács Viktória Szőke Gábor Szigligeti János Leszkoven Daniel Collins Patrick Breen Stephen Frohlich Ruth Whelan Bairbre McNicholas Michael Scully Siobhan Casey Maeve Kernan Peter Doran Michael O’Dywer Michelle Smyth Leanne Hayes Oscar Hoiting Marco Peters Els Rengers Mirjam Evers Anton Prinssen Jeroen Bosch Ziekenhuis Koen Simons Wim Rozendaal F Polderman P de Jager M Moviat A Paling A Salet Emma Rademaker Anna Linda Peters E de Jonge J Wigbers E Guilder M Butler Keri-Anne Cowdrey Lynette Newby Yan Chen Catherine Simmonds Rachael McConnochie Jay Ritzema Carter Seton Henderson Kym Van Der Heyden Jan Mehrtens Tony Williams Alex Kazemi Rima Song Vivian Lai Dinu Girijadevi Robert Everitt Robert Russell Danielle Hacking Ulrike Buehner Erin Williams Troy Browne Kate Grimwade Jennifer Goodson Owen Keet Owen Callender Robert Martynoga Kara Trask Amelia Butler Livia Schischka Chelsea Young Eden Lesona Shaanti Olatunji Yvonne Robertson Nuno José Teodoro Amaro dos Santos Catorze Tiago Nuno Alfaro de Lima Pereira Lucilia Maria Neves Pessoa Ricardo Manuel Castro Ferreira Joana Margarida Pereira Sousa Bastos Simin Aysel Florescu Delia Stanciu Miahela Florentina Zaharia Alma Gabriela Kosa Daniel Codreanu Yaseen Marabi Eman Al Qasim Mohamned Moneer Hagazy Lolowa Al Swaidan Hatim Arishi Rosana Muñoz-Bermúdez Judith Marin-Corral Anna Salazar Degracia Francisco Parrilla Gómez Maria Isabel Mateo López Jorge Rodriguez Fernandez Sheila Cárcel Fernández Rosario Carmona Flores Rafael León López Carmen de la Fuente Martos Angela Allan Petra Polgarova Neda Farahi Stephen McWilliam Daniel Hawcutt Laura Rad Laura O’Malley Jennifer Whitbread Olivia Kelsall Laura Wild Jessica Thrush Hannah Wood Karen Austin Adrian Donnelly Martin Kelly Sinéad O’Kane Declan McClintock Majella Warnock Paul Johnston Linda Jude Gallagher Clare Mc Goldrick Moyra Mc Master Anna Strzelecka Rajeev Jha Michael Kalogirou Christine Ellis Vinodh Krishnamurthy Vashish Deelchand Jon Silversides Peter McGuigan Kathryn Ward Aisling O’Neill Stephanie Finn Barbara Phillips Dee Mullan Laura Oritz-Ruiz de Gordoa Matthew Thomas Katie Sweet Lisa Grimmer Rebekah Johnson Jez Pinnell Matt Robinson Lisa Gledhill Tracy Wood Matt Morgan Jade Cole Helen Hill Michelle Davies David Antcliffe Maie Templeton Roceld Rojo Phoebe Coghlan Joanna Smee Euan Mackay Jon Cort Amanda Whileman Thomas Spencer Nick Spittle Vidya Kasipandian Amit Patel Suzanne Allibone Roman Mary Genetu Mohamed Ramali Alison Ghosh Peter Bamford Emily London Kathryn Cawley Maria Faulkner Helen Jeffrey Tim Smith Chris Brewer Jane Gregory James Limb Amanda Cowton Julie O’Brien Nikitas Nikitas Colin Wells Liana Lankester Mark Pulletz Patricia Williams Jenny Birch Sophie Wiseman Sarah Horton Ana Alegria Salah Turki Tarek Elsefi Nikki Crisp Louise Allen Iain McCullagh Philip Robinson Carole Hays Maite Babio-Galan Hannah Stevenson Divya Khare Meredith Pinder Selvin Selvamoni Amitha Gopinath Richard Pugh Daniel Menzies Callum Mackay Elizabeth Allan Gwyneth Davies Kathryn Puxty Claire McCue Susanne Cathcart Naomi Hickey Jane Ireland Hakeem Yusuff Graziella Isgro Chris Brightling Michelle Bourne Michelle Craner Malcolm Watters Rachel Prout Louisa Davies Suzannah Pegler Lynsey Kyeremeh Gill Arbane Karen Wilson Linda Gomm Federica Francia Stephen Brett Sonia Sousa Arias Rebecca Elin Hall Joanna Budd Charlotte Small Janine Birch Emma Collins Jeremy Henning Stephen Bonner Keith Hugill Emanuel Cirstea Dean Wilkinson Michal Karlikowski Helen Sutherland Elva Wilhelmsen Jane Woods Julie North Dhinesh Sundaran Laszlo Hollos Susan Coburn Joanne Walsh Margaret Turns Phil Hopkins John Smith Harriet Noble Maria Theresa Depante Emma Clarey Shondipon Laha Mark Verlander Alexandra Williams Abby Huckle Andrew Hall Jill Cooke Caroline Gardiner-Hill Carolyn Maloney Hafiz Qureshi Neil Flint Sarah Nicholson Sara Southin Andrew Nicholson Barbara Borgatta Ian Turner-Bone Amie Reddy Laura Wilding Loku Chamara Warnapura Ronan Agno Sathianathan David Golden Ciaran Hart Jo Jones Jonathan Bannard-Smith Joanne Henry Katie Birchall Fiona Pomeroy Rachael Quayle Arystarch Makowski Beata Misztal Iram Ahmed Thyra KyereDiabour Kevin Naiker Richard Stewart Esther Mwaura Louise Mew Lynn Wren Felicity Willams Richard Innes Patricia Doble Joanne Hutter Charmaine Shovelton Benjamin Plumb Tamas Szakmany Vincent Hamlyn Nancy Hawkins Sarah Lewis Amanda Dell Shameer Gopal Saibal Ganguly Andrew Smallwood Nichola Harris Stella Metherell Juan Martin Lazaro Tabitha Newman Simon Fletcher Jurgens Nortje Deirdre Fottrell-Gould Georgina Randell Mohsin Zaman Einas Elmahi Andrea Jones Kathryn Hall Gary Mills Kim Ryalls Helen Bowler Jas Sall Richard Bourne Zoe Borrill Tracey Duncan Thomas Lamb Joanne Shaw Claire Fox Jeronimo Moreno Cuesta Kugan Xavier Dharam Purohit Munzir Elhassan Dhanalakshmi Bakthavatsalam Matthew Rowland Paula Hutton Archana Bashyal Neil Davidson Clare Hird Manish Chhablani Gunjan Phalod Amy Kirkby Simon Archer Kimberley Netherton Henrik Reschreiter Julie Camsooksai Sarah Patch Sarah Jenkins David Pogson Steve Rose Zoe Daly Lutece Brimfield Helen Claridge Dhruv Parekh Colin Bergin Michelle Bates Joanne Dasgin Christopher McGhee Malcolm Sim Sophie Kennedy Hay Steven Henderson Mandeep-Kaur Phull Abbas Zaidi Tatiana Pogreban Lace Paulyn Rosaroso Daniel Harvey Benjamin Lowe Megan Meredith Lucy Ryan Anil Hormis Rachel Walker Dawn Collier Sarah Kimpton Susan Oakley Kevin Rooney Natalie Rodden Emma Hughes Nicola Thomson Deborah McGlynn Andrew Walden Nicola Jacques Holly Coles Emma Tilney Emma Vowell Martin Schuster-Bruce Sally Pitts Rebecca Miln Laura Purandare Luke Vamplew Michael Spivey Sarah Bean Karen Burt Lorraine Moore Christopher Day Charly Gibson Elizabeth Gordon Letizia Zitter Samantha Keenan Evelyn Baker Shiney Cherian Sean Cutler Anna Roynon-Reed Kate Harrington Ajay Raithatha Kris Bauchmuller Norfaizan Ahmad Irina Grecu Dawn Trodd Jane Martin Caroline Wrey Brown Ana-Marie Arias Thomas Craven David Hope Jo Singleton Sarah Clark Nicola Rae Ingeborg Welters David Oliver Hamilton Karen Williams Victoria Waugh David Shaw Zudin Puthucheary Timothy Martin Filipa Santos Ruzena Uddin Alastair Somerville Kate Colette Tatham Shaman Jhanji Ethel Black Arnold Dela Rosa Ryan Howle Redmond Tully Andrew Drummond Joy Dearden Jennifer Philbin Sheila Munt Alain Vuylsteke Charles Chan Saji Victor Ramprasad Matsa Minerva Gellamucho Ben Creagh-Brown Joe Tooley Laura Montague Fiona De Beaux Laetitia Bullman Ian Kersiake Carrie Demetriou Sarah Mitchard Lidia Ramos Katie White Phil Donnison Maggie Johns Ruth Casey Lehentha Mattocks Sarah Salisbury Paul Dark Andrew Claxton Danielle McLachlan Kathryn Slevin Stephanie Lee Jonathan Hulme Sibet Joseph Fiona Kinney Ho Jan Senya Aneta Oborska Abdul Kayani Bernard Hadebe Rajalakshmi Orath Prabakaran Lesley Nichols Matt Thomas Ruth Worner Beverley Faulkner Emma Gendall Kati Hayes Colin Hamilton-Davies Carmen Chan Celina Mfuko Hakam Abbass Vineela Mandadapu Susannah Leaver Daniel Forton Kamal Patel Elankumaran Paramasivam Matthew Powell Richard Gould Elizabeth Wilby Clare Howcroft Dorota Banach Ziortza Fernández de Pinedo Artaraz Leilani Cabreros Ian White Maria Croft Nicky Holland Rita Pereira Ahmed Zaki David Johnson Matthew Jackson Hywel Garrard Vera Juhaz Alistair Roy Anthony Rostron Lindsey Woods Sarah Cornell Suresh Pillai Rachel Harford Tabitha Rees Helen Ivatt Ajay Sundara Raman Miriam Davey Kelvin Lee Russell Barber Manish Chablani Farooq Brohi Vijay Jagannathan Michele Clark Sarah Purvis Bill Wetherill Ahilanandan Dushianthan Rebecca Cusack Kim de Courcy-Golder Simon Smith Susan Jackson Ben Attwood Penny Parsons Valerie Page Xiao Bei Zhao Deepali Oza Jonathan Rhodes Tom Anderson Sheila Morris Charlotte Xia Le Tai Amy Thomas Alexandra Keen Stephen Digby Nicholas Cowley Laura Wild David Southern Harsha Reddy Andy Campbell Claire Watkins Sara Smuts Omar Touma Nicky Barnes Peter Alexander Tim Felton Susan Ferguson Katharine Sellers Joanne Bradley-Potts David Yates Isobel Birkinshaw Kay Kell Nicola Marshall Lisa Carr-Knott

JAMA 2020 10;324(13):1317-1329

Division of Anaesthetics, Pain Medicine and Intensive Care Medicine, Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom.

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October 2020

GINA fosters World Asthma Day 2020 to prevent asthma deaths.

Am J Physiol Lung Cell Mol Physiol 2020 05 19;318(5):L998-L1000. Epub 2020 Mar 19.

Member of GINA Board of Directors and GINA Science Committee; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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May 2020

Sputum microbiome profiling in COPD: beyond singular pathogen detection.

Thorax 2020 04 29;75(4):338-344. Epub 2020 Jan 29.

Department of Pulmonary Diseases, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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April 2020

Increased ventilation heterogeneity in asthma can be attributed to proximal bronchioles.

Eur Respir J 2020 03 12;55(3). Epub 2020 Mar 12.

Respiratory Division, University Hospital UZBrussel, Brussels, Belgium

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March 2020

Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum.

BMC Pulm Med 2019 Aug 8;19(1):144. Epub 2019 Aug 8.

Institute for Lung Health NIHR Leicester Biomedical Research Centre Department of Respiratory Sciences, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, LE3 9QP, UK.

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August 2019

Functional CT imaging for identification of the spatial determinants of small-airways disease in adults with asthma.

J Allergy Clin Immunol 2019 07 22;144(1):83-93. Epub 2019 Jan 22.

NIHR Respiratory Biomedical Research Centre (BRC), Department of Respiratory Sciences, University of Leicester, Leicester, United Kingdom. Electronic address:

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July 2019

Exacerbations of severe asthma in patients treated with mepolizumab.

Eur Respir J 2018 12 13;52(6). Epub 2018 Dec 13.

Dept of Respiratory Medicine, Allergy and Thoracic Surgery and NIHR BRC Respiratory Theme, Glenfield Hospital, University of Leicester, Leicester, UK.

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December 2018

ERS Clinical Research Collaborations: underpinning research excellence.

Eur Respir J 2018 09 15;52(3). Epub 2018 Sep 15.

Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.

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September 2018

Urgent need for pragmatic trial platforms in severe asthma.

Lancet Respir Med 2018 08;6(8):581-583

Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Departments of Epidemiology and Respiratory Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands. Electronic address:

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August 2018

Modelling the effect of gravity on inert-gas washout outputs.

Physiol Rep 2018 05;6(10):e13709

Department of Computer Science, University of Oxford, Oxford, Oxfordshire, United Kingdom.

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May 2018

Big asthma data: getting bigger and more beautiful?

Thorax 2018 04 29;73(4):311-312. Epub 2017 Dec 29.

Department of Infection, Immunity and Inflammation, Leicester NIHR BRC, Institute for Lung Health, University of Leicester, Leicester, UK.

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April 2018

MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma.

Chest 2017 10 14;152(4):771-779. Epub 2017 Jul 14.

Institute for Lung Health, National Institute for Health Research Leicester Biomedical Research Centre, and Department of Infection Immunity and Inflammation, University of Leicester, and University Hospitals Leicester, Children's Hospital, Leicester, England. Electronic address:

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October 2017

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

Authors:
Louise V Wain Nick Shrine María Soler Artigas A Mesut Erzurumluoglu Boris Noyvert Lara Bossini-Castillo Ma'en Obeidat Amanda P Henry Michael A Portelli Robert J Hall Charlotte K Billington Tracy L Rimington Anthony G Fenech Catherine John Tineka Blake Victoria E Jackson Richard J Allen Bram P Prins Archie Campbell David J Porteous Marjo-Riitta Jarvelin Matthias Wielscher Alan L James Jennie Hui Nicholas J Wareham Jing Hua Zhao James F Wilson Peter K Joshi Beate Stubbe Rajesh Rawal Holger Schulz Medea Imboden Nicole M Probst-Hensch Stefan Karrasch Christian Gieger Ian J Deary Sarah E Harris Jonathan Marten Igor Rudan Stefan Enroth Ulf Gyllensten Shona M Kerr Ozren Polasek Mika Kähönen Ida Surakka Veronique Vitart Caroline Hayward Terho Lehtimäki Olli T Raitakari David M Evans A John Henderson Craig E Pennell Carol A Wang Peter D Sly Emily S Wan Robert Busch Brian D Hobbs Augusto A Litonjua David W Sparrow Amund Gulsvik Per S Bakke James D Crapo Terri H Beaty Nadia N Hansel Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Yohan Bossé Philippe Joubert Maarten van den Berge Corry-Anke Brandsma Peter D Paré Don D Sin David C Nickle Ke Hao Omri Gottesman Frederick E Dewey Shannon E Bruse David J Carey H Lester Kirchner Stefan Jonsson Gudmar Thorleifsson Ingileif Jonsdottir Thorarinn Gislason Kari Stefansson Claudia Schurmann Girish Nadkarni Erwin P Bottinger Ruth J F Loos Robin G Walters Zhengming Chen Iona Y Millwood Julien Vaucher Om P Kurmi Liming Li Anna L Hansell Chris Brightling Eleftheria Zeggini Michael H Cho Edwin K Silverman Ian Sayers Gosia Trynka Andrew P Morris David P Strachan Ian P Hall Martin D Tobin

Nat Genet 2017 Mar 6;49(3):416-425. Epub 2017 Feb 6.

Department of Health Sciences, University of Leicester, Leicester, UK.

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March 2017

Sputum Inflammatory Mediators Are Increased in Aspergillus fumigatus Culture-Positive Asthmatics.

Allergy Asthma Immunol Res 2017 Mar;9(2):177-181

Institute for Lung Health, NIHR Respiratory Biomedical Research Unit, Department of Infection, Immunity & Inflammation, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, UK.

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March 2017

Comparison of CT-based Lobar Ventilation with 3He MR Imaging Ventilation Measurements.

Radiology 2016 Feb 28;278(2):585-92. Epub 2015 Aug 28.

From the Academic Units of Academic Radiology (B.A.T., A.J.S., F.C.H., H.M., J.C.K., J.P.R., J.M.W.) and Clinical Oncology (B.A.T., R.H.I.), University of Sheffield, C Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, England; Fluidda, Kontich, Belgium (C.V.H., J.D.B., W.V.); Institute for Lung Health, University of Leicester, Leicester, England (R.H., C.E.B.); Novartis, Basel, Switzerland (R.K.); and INSIGNEO Institute of In-silico Medicine, Sheffield, England (A.J.S., J.M.W.).

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February 2016

Novel imaging approaches in adult asthma and their clinical potential.

Expert Rev Clin Immunol 2015 7;11(10):1147-62. Epub 2015 Aug 7.

a 1 Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, LE3 9QP, UK.

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June 2016

Dynamic flow characteristics in normal and asthmatic lungs.

Int J Numer Method Biomed Eng 2015 Dec 25;31(12). Epub 2015 Jun 25.

Department of Computer Science, University of Oxford, Oxford, UK.

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December 2015

Toll-like receptor 9 dependent interferon-α release is impaired in severe asthma but is not associated with exacerbation frequency.

Immunobiology 2015 Jul 22;220(7):859-64. Epub 2015 Jan 22.

Institute of Lung Health, Respiratory Biomedical Unit, University Hospitals of Leicester NHS Trust, Leicestershire, UK; Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.

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July 2015

Relationship between blood and bronchial submucosal eosinophilia and reticular basement membrane thickening in chronic obstructive pulmonary disease.

Respirology 2015 May 27;20(4):667-70. Epub 2015 Jan 27.

Institute for Lung Health, Department of Infection, Immunity & Inflammation, University of Leicester, Leicester, UK; Department of Medicine, Faculty of Medicine, Benghazi University, Benghazi, Libya.

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May 2015

Eosinophilic inflammation in COPD: prevalence and clinical characteristics.

Eur Respir J 2014 Dec 16;44(6):1697-700. Epub 2014 Oct 16.

GlaxoSmithKline, Research and Development, King of Prussia, PA, USA.

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December 2014

Biological clustering supports both "Dutch" and "British" hypotheses of asthma and chronic obstructive pulmonary disease.

J Allergy Clin Immunol 2015 Jan 13;135(1):63-72. Epub 2014 Aug 13.

Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, United Kingdom; NIHR Respiratory Biomedical Research Unit, University Hospitals of Leicester, Leicester, United Kingdom. Electronic address:

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January 2015

Statistical cluster analysis of the British Thoracic Society Severe refractory Asthma Registry: clinical outcomes and phenotype stability.

PLoS One 2014 24;9(7):e102987. Epub 2014 Jul 24.

Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, United Kingdom.

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April 2015

Reply: Elevated sputum IL-5 and submucosal eosinophilia in obese individuals with severe asthma.

Am J Respir Crit Care Med 2014 May;189(10):1285-6

1 University of Leicester Leicester, United Kingdom and.

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May 2014

Reply: Role of primary necrosis/lysis of submucosal eosinophils in obese individuals with asthma.

Am J Respir Crit Care Med 2013 Dec;188(12):1468-9

1 University of Leicester Leicester, United Kingdom and University Hospitals of Leicester NHS Trust Leicester, United Kingdom.

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December 2013

Clinical management and outcome of refractory asthma in the UK from the British Thoracic Society Difficult Asthma Registry.

Thorax 2012 Aug 11;67(8):754-6. Epub 2012 May 11.

Centre for Infection and Immunity, Queen's University of Belfast, Lisburn Road, Belfast, UK.

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August 2012

Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma.

Am J Respir Crit Care Med 2012 Feb 22;185(3):267-74. Epub 2011 Nov 22.

Institute for Lung Health, Department of Infection, Immunity and Inflammation, University of Leicester, United Kingdom.

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February 2012

Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma.

J Immunol 2011 Dec 24;187(11):6094-107. Epub 2011 Oct 24.

Nottingham Respiratory Biomedical Research Unit, University of Nottingham, Nottingham NG5 1PB, United Kingdom.

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December 2011

Functional KCa3.1 K+ channels are required for human fibrocyte migration.

J Allergy Clin Immunol 2011 Dec 27;128(6):1303-1309.e2. Epub 2011 Aug 27.

Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, United Kingdom.

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December 2011

Eosinophils best marker of steroid response.

Thorax 2011 Aug 23;66(8):730; author reply 730-1. Epub 2010 Sep 23.

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August 2011

Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry.

Thorax 2010 Sep;65(9):787-94

Centre for Infection and Immunity, Queen's University of Belfast, Level 8, Belfast City Hospital, Lisburn Road, Belfast BT9 7AB, UK.

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September 2010

Mannitol and AMP do not induce bronchoconstriction in eosinophilic bronchitis: further evidence for dissociation between airway inflammation and bronchial hyperresponsiveness.

Respirology 2010 Apr 24;15(3):510-5. Epub 2010 Feb 24.

Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.

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April 2010

Cough due to asthma, cough-variant asthma and non-asthmatic eosinophilic bronchitis.

Otolaryngol Clin North Am 2010 Feb;43(1):123-30, x

Department of Infection, Inflammation, and Immunity, University of Leicester, Institute for Lung Health, Glenfield Hospital, UK.

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February 2010

Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration.

Eur J Immunol 2008 Sep;38(9):2548-56

The Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, UK.

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September 2008

KCa3.1 Ca2+ activated K+ channels regulate human airway smooth muscle proliferation.

Am J Respir Cell Mol Biol 2007 Nov 21;37(5):525-31. Epub 2007 Jun 21.

Division of Immunology, Infection and Inflammation, University of Glasgow, Glasgow, United Kingdom.

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November 2007

The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial.

Am J Respir Crit Care Med 2007 Aug 11;176(3):231-7. Epub 2007 May 11.

Institute for Lung Health, Department of Respiratory Medicine and Thoracic Surgery, Glenfield Hospital, Leicester, United Kingdom.

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August 2007

Mast cell infiltration of airway smooth muscle in asthma.

Respir Med 2007 May 15;101(5):1045; author reply 1046-7. Epub 2007 Feb 15.

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May 2007

The reclassification of asthma based on subphenotypes.

Curr Opin Allergy Clin Immunol 2007 Feb;7(1):43-50

Department of Respiratory Medicine, Glenfield Hospital, Groby Road, Leicester, UK.

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February 2007

The influence of age on induced sputum differential cell counts in normal subjects.

Chest 2004 Dec;126(6):1811-4

Department of Respiratory Medicine, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UK.

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December 2004