Publications by authors named "Choong-Leong Tang"

61Publications

Results of a colorectal enhanced recovery after surgery (ERAS) programme and a qualitative analysis of healthcare workers' perspectives.

Asian J Surg 2020 Aug 27. Epub 2020 Aug 27.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.

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http://dx.doi.org/10.1016/j.asjsur.2020.07.020DOI Listing
August 2020

Stenting as a bridge to surgery for obstructed stage IV colorectal cancers - long-term outcomes of a 10-year study.

Asian J Endosc Surg 2020 Jul 22;13(3):343-350. Epub 2019 Aug 22.

Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1111/ases.12747DOI Listing
July 2020

Gracilis pull-through flap for the repair of a recalcitrant recto-vaginal fistula.

Arch Plast Surg 2019 May 15;46(3):277-281. Epub 2019 May 15.

Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore.

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http://e-aps.org/journal/view.php?doi=10.5999/aps.2018.00416
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http://dx.doi.org/10.5999/aps.2018.00416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536868PMC
May 2019

Totally-laparoscopic versus laparoscopic-assisted low anterior resection for rectal cancer: are outcomes different?

ANZ J Surg 2018 12 13;88(12):E818-E823. Epub 2018 Sep 13.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/ans.14841DOI Listing
December 2018

Human colorectal cancer initiation is bidirectional, and cell growth, metabolic genes and transporter genes are early drivers of tumorigenesis.

Cancer Lett 2018 09 6;431:213-218. Epub 2018 Jun 6.

Department of Colorectal Surgery, Singapore General Hospital, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835183040
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http://dx.doi.org/10.1016/j.canlet.2018.06.005DOI Listing
September 2018

Systematic review and meta-analysis of the use of serum procalcitonin levels to predict intra-abdominal infections after colorectal surgery.

Int J Colorectal Dis 2018 Feb 5;33(2):171-180. Epub 2018 Jan 5.

Department of Colorectal Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://link.springer.com/10.1007/s00384-017-2956-8
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http://dx.doi.org/10.1007/s00384-017-2956-8DOI Listing
February 2018

GREM1 Defect Unlikely to be Disease Causing and Hence Not Useful for Screening and Surveillance in Singapore Mixed Polyposis Families.

Gastroenterology 2017 12 3;153(6):1692. Epub 2017 Nov 3.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1053/j.gastro.2017.04.057DOI Listing
December 2017

Genome-wide association study identified copy number variants associated with sporadic colorectal cancer risk.

J Med Genet 2018 03 27;55(3):181-188. Epub 2017 Oct 27.

Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1136/jmedgenet-2017-104913DOI Listing
March 2018

A Novel Derivation Predicting Survival After Primary Tumor Resection in Stage IV Colorectal Cancer: Validation of a Prognostic Scoring Model and an Online Calculator to Provide Individualized Survival Estimation.

Dis Colon Rectum 2017 Sep;60(9):895-904

1 Department of Colorectal Surgery, Singapore General Hospital, Singapore 2 Department of Pharmacy, National University of Singapore, Singapore 3 Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1097/DCR.0000000000000821DOI Listing
September 2017

Rectal Cancer Surveillance-Recurrence Patterns and Survival Outcomes from a Cohort Followed up Beyond 10 Years.

J Gastrointest Cancer 2018 Dec;49(4):422-428

Department of Colorectal Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s12029-017-9984-zDOI Listing
December 2018

A formalin-fixed paraffin-embedded (FFPE)-based prognostic signature to predict metastasis in clinically low risk stage I/II microsatellite stable colorectal cancer.

Cancer Lett 2017 09 15;403:13-20. Epub 2017 Jun 15.

Department of Colorectal Surgery, Singapore General Hospital, 169856, Singapore; SingHealth Duke-NUS Surgery Academic Clinical Programme, Office of Clinical, Academic and Faculty Affairs, Duke-NUS Medical School, National University of Singapore, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.05.031DOI Listing
September 2017

Evaluation of Long-Term Outcomes of Microsatellite Instability Status in an Asian Cohort of Sporadic Colorectal Cancers.

J Gastrointest Cancer 2018 Sep;49(3):311-318

Department of Colorectal Surgery, Singapore General Hospital, 20 College Road, Academia, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s12029-017-9953-6DOI Listing
September 2018

Methylation of serum gene is an independent prognostic marker in colorectal cancer.

Am J Cancer Res 2016 1;6(9):2098-2108. Epub 2016 Sep 1.

Department of Clinical Research, Singapore General Hospital Singapore.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043118PMC
September 2016

Critical appraisal of laparoscopic vs open rectal cancer surgery.

World J Gastrointest Surg 2016 Jun;8(6):452-60

Winson Jianhong Tan, Min Hoe Chew, Angela Renayanti Dharmawan, Manraj Singh, Carol Tien Tau Loi, Choong Leong Tang, Department of Colorectal Surgery, Singapore General Hospital, Singapore 169856, Singapore.

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http://www.wjgnet.com/1948-9366/full/v8/i6/452.htm
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http://dx.doi.org/10.4240/wjgs.v8.i6.452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919713PMC
June 2016

Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis.

Proc Natl Acad Sci U S A 2015 Nov 2;112(46):E6349-58. Epub 2015 Nov 2.

Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore 169610, Singapore; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore 169857, Singapore; Department of Biochemistry, National University of Singapore, Singapore 117597, Singapore

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http://dx.doi.org/10.1073/pnas.1510043112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655557PMC
November 2015

Genomics of Hereditary Colorectal Cancer: Lessons Learnt from 25 Years of the Singapore Polyposis Registry.

Ann Acad Med Singap 2015 Aug;44(8):290-6

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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August 2015

Analysis of colorectal cancer glyco-secretome identifies laminin β-1 (LAMB1) as a potential serological biomarker for colorectal cancer.

Proteomics 2015 Nov 26;15(22):3905-20. Epub 2015 Oct 26.

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

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http://dx.doi.org/10.1002/pmic.201500236DOI Listing
November 2015

Prevalence of faecal incontinence in the community: a cross-sectional study in Singapore.

Singapore Med J 2014 Dec;55(12):640-3

Department of Colorectal Surgery, Singapore General Hospital, 20 College Road, Academia Level 5, Singapore 169856.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292001PMC
http://dx.doi.org/10.11622/smedj.2014177DOI Listing
December 2014

Short and long-term outcomes of a randomised controlled trial of vertical periumbilical wound versus transverse left iliac fossa wound for specimen retrieval in laparoscopic anterior resections.

Surg Endosc 2015 Sep 6;29(9):2720-7. Epub 2014 Dec 6.

Department of Colorectal Surgery, Singapore General Hospital, Academia, 20 College Road, Singapore, 169856, Singapore,

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http://dx.doi.org/10.1007/s00464-014-3994-8DOI Listing
September 2015

Jejunojejunal intussusception secondary to submucosal lipoma resulting in a 5-year history of intermittent abdominal pain.

BMJ Case Rep 2014 Oct 29;2014. Epub 2014 Oct 29.

Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore.

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http://dx.doi.org/10.1136/bcr-2014-207297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216885PMC
October 2014

Evolution of laparoscopy in colorectal surgery: an evidence-based review.

World J Gastroenterol 2014 May;20(17):4926-33

Alexander Emmanuel Blackmore, Mark Te Ching Wong, Choong Leong Tang, Department of Colorectal Surgery, Singapore General Hospital, Singapore 169856, Singapore.

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http://dx.doi.org/10.3748/wjg.v20.i17.4926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009524PMC
May 2014

Risk prediction score in laparoscopic colorectal surgery training: experience from the English National Training Program.

Ann Surg 2015 Feb;261(2):338-44

*Department of Surgery and Cancer, St Mary's Hospital, Imperial College London, London, United Kingdom †John Golligher Colorectal Unit, The Leeds Teaching Hospitals, Leeds, United Kingdom ‡Department of Colorectal Surgery, Singapore General Hospital, Singapore §Department of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, OH; and ‖Department of Colorectal Surgery, Derriford Hospital, Plymouth, United Kingdom.

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http://dx.doi.org/10.1097/SLA.0000000000000651DOI Listing
February 2015

A novel indel in exon 9 of APC upregulates a 'skip exon 9' isoform and causes very severe familial adenomatous polyposis.

Eur J Hum Genet 2014 Jun 30;22(6):833-6. Epub 2013 Oct 30.

Department of Colorectal Surgery, Singapore General Hospital, Singapore, Republic of Singapore.

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http://dx.doi.org/10.1038/ejhg.2013.245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023219PMC
June 2014

Mismatch repair deficiency screening via immunohistochemical staining in young Asians with colorectal cancers.

World J Surg 2013 Oct;37(10):2468-75

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.

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http://dx.doi.org/10.1007/s00268-013-2134-2DOI Listing
October 2013

Opportunistic screening for colorectal neoplasia in Singapore using faecal immunochemical occult blood test.

Singapore Med J 2013 Apr;54(4):220-3

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore.

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http://dx.doi.org/10.11622/smedj.2013077DOI Listing
April 2013

Toxic haemorrhagic colitis: a rare presentation of eosinophilic colitis.

Case Rep Gastrointest Med 2012 10;2012:279813. Epub 2012 Sep 10.

Department of Colorectal Surgery, Singapore General Hospital, 169608, Singapore.

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http://dx.doi.org/10.1155/2012/279813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444833PMC
September 2012

Close distal margins do not increase rectal cancer recurrence after sphincter-saving surgery without neoadjuvant therapy.

Int J Colorectal Dis 2012 Oct 24;27(10):1285-94. Epub 2012 Aug 24.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore.

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http://dx.doi.org/10.1007/s00384-012-1467-xDOI Listing
October 2012

Conventional laparoscopic versus single-incision laparoscopic right hemicolectomy: a case cohort comparison of short-term outcomes in 144 consecutive cases.

Surg Endosc 2013 Feb 18;27(2):471-7. Epub 2012 Jul 18.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.

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http://dx.doi.org/10.1007/s00464-012-2460-8DOI Listing
February 2013

Biofeedback is an effective treatment for patients with dyssynergic defaecation.

Singapore Med J 2012 Jun;53(6):381-4

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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http://smj.sma.org.sg/5306/5306a2.pdf
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June 2012

Evaluation of laparoscopic versus open colorectal surgery in elderly patients more than 70 years old: an evaluation of 727 patients.

Int J Colorectal Dis 2012 Jun 3;27(6):773-80. Epub 2011 Dec 3.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore, 169608.

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http://link.springer.com/10.1007/s00384-011-1375-5
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http://dx.doi.org/10.1007/s00384-011-1375-5DOI Listing
June 2012

Endoscopic stenting and elective surgery versus emergency surgery for left-sided malignant colonic obstruction: a prospective randomized trial.

Int J Colorectal Dis 2012 Mar 28;27(3):355-62. Epub 2011 Oct 28.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Republic of Singapore.

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http://dx.doi.org/10.1007/s00384-011-1331-4DOI Listing
March 2012

Stage IV colorectal cancers: an analysis of factors predicting outcome and survival in 728 cases.

J Gastrointest Surg 2012 Mar 19;16(3):603-12. Epub 2011 Oct 19.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.

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http://dx.doi.org/10.1007/s11605-011-1725-1DOI Listing
March 2012

Laparoscopic resection for colorectal polyps: a single institution experience.

ANZ J Surg 2011 Apr 22;81(4):275-80. Epub 2010 Dec 22.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/j.1445-2197.2010.05580.xDOI Listing
April 2011

Results of 7302 stapled haemorrhoidectomy operations in a single centre: a seven-year review and follow-up questionnaire survey.

ANZ J Surg 2011 Apr 16;81(4):253-6. Epub 2010 Sep 16.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/j.1445-2197.2010.05478.xDOI Listing
April 2011

Stapled anastomosis for anterior resection is safe even after previous stapled haemorrhoidectomy--a report of five cases.

Int J Colorectal Dis 2010 Dec 25;25(12):1503-6. Epub 2010 Jun 25.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608, Singapore, Republic of Singapore.

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http://link.springer.com/10.1007/s00384-010-0994-6
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http://dx.doi.org/10.1007/s00384-010-0994-6DOI Listing
December 2010

Peutz-Jeghers syndrome: data from the Singapore Polyposis Registry and a shifting paradigm in management.

Ann Acad Med Singap 2010 Jan;39(1):17-21

Department of General Surgery, Singapore General Hospital, Singapore.

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January 2010

Laparoscopic versus open right hemicolectomy: a comparison of short-term outcomes.

Int J Colorectal Dis 2009 Nov 2;24(11):1333-9. Epub 2009 Jun 2.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, 169608 Singapore, Singapore.

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http://dx.doi.org/10.1007/s00384-009-0743-xDOI Listing
November 2009

The evaluation of CEEA 34 for stapled hemorrhoidectomy: results of a prospective clinical trial and patient satisfaction.

Am J Surg 2009 Jun 7;197(6):695-701. Epub 2008 Sep 7.

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1016/j.amjsurg.2008.01.033DOI Listing
June 2009

Charity colonoscopy event to commemorate the 185th anniversary of Singapore General Hospital.

Ann Acad Med Singap 2008 Mar;37(3):180-3

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore.

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March 2008

Cutaneous and subcutaneous metastases of adenocarcinoma of the colon and rectum.

Ann Acad Med Singap 2006 Aug;35(8):585-7

Department of Colorectal Surgery, Singapore General Hospital, Singapore.

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August 2006

A systematic review of the function and complications of colonic pouches.

Int J Colorectal Dis 2007 May 13;22(5):543-8. Epub 2006 Sep 13.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Singapore.

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http://dx.doi.org/10.1007/s00384-006-0187-5DOI Listing
May 2007

Digital rectal examination compares favourably with conventional water-soluble contrast enema in the assessment of anastomotic healing after low rectal excision: a cohort study.

Int J Colorectal Dis 2005 May 29;20(3):262-6. Epub 2004 Sep 29.

Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore 168609, Singapore.

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http://link.springer.com/10.1007/s00384-004-0652-y
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http://dx.doi.org/10.1007/s00384-004-0652-yDOI Listing
May 2005

Colonic epithelial atrophy induced by a fibre-free diet in rats is reversed by minimal amounts of luminal butyrate, but only in the short term.

ANZ J Surg 2002 Dec;72(12):871-6

University of Melbourne, Department of Surgery, The Royal Melbourne Hospital, Victoria, Australia.

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http://dx.doi.org/10.1046/j.1445-2197.2002.t01-1-02586.xDOI Listing
December 2002

Development of a chronic colonic intubation model in rats for the study of luminal factors in colonic diseases.

Dis Colon Rectum 2002 Feb;45(2):256-63

Department of Colorectal Surgery, University of Melbourne, Royal Melbourne Hospital, Parkville, Australia.

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http://pdfs.journals.lww.com/dcrjournal/2002/45020/Developme
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http://dx.doi.org/10.1007/s10350-004-6157-5DOI Listing
February 2002