Choon-Hong Tan

Choon-Hong Tan

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Choon-Hong Tan

Publications by authors named "Choon-Hong Tan"

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Itaconimides as Novel Quorum Sensing Inhibitors of .

Front Cell Infect Microbiol 2018 7;8:443. Epub 2019 Jan 7.

Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore.

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http://dx.doi.org/10.3389/fcimb.2018.00443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330316PMC
September 2019

Correction to Halogen-Bonding-Induced Hydrogen Transfer to C═N Bond with Hantzsch Ester.

Org Lett 2019 Sep 5;21(18):7684. Epub 2019 Sep 5.

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http://dx.doi.org/10.1021/acs.orglett.9b02822DOI Listing
September 2019

Recent Advances in Chiral Guanidine Catalyzed Enantioselective Reactions.

Chem Asian J 2019 Sep 27. Epub 2019 Sep 27.

TAIWAN.

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http://dx.doi.org/10.1002/asia.201901183DOI Listing
September 2019

Halogen-Bonding-Induced Conjugate Addition of Thiophenes to Enones and Enals.

Chem Asian J 2019 Aug 10;14(15):2656-2661. Epub 2019 Jul 10.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore.

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http://dx.doi.org/10.1002/asia.201900607DOI Listing
August 2019

Metal-catalysed reactions enabled by guanidine-type ligands.

Org Biomol Chem 2019 May;17(19):4689-4699

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371.

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http://xlink.rsc.org/?DOI=C8OB02240B
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http://dx.doi.org/10.1039/c8ob02240bDOI Listing
May 2019

Guanidine-Copper Complex Catalyzed Allylic Borylation for the Enantioconvergent Synthesis of Tertiary Cyclic Allylboronates.

Angew Chem Int Ed Engl 2019 Feb 24;58(8):2382-2386. Epub 2019 Jan 24.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore.

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http://dx.doi.org/10.1002/anie.201813490DOI Listing
February 2019

Hyperfast Water Transport through Biomimetic Nanochannels from Peptide-Attached (pR)-pillar[5]arene.

Small 2019 Feb 13;15(6):e1804678. Epub 2019 Jan 13.

Singapore Membrane Technology Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, Singapore, 637141, Singapore.

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http://dx.doi.org/10.1002/smll.201804678DOI Listing
February 2019

An enantioconvergent halogenophilic nucleophilic substitution (S2X) reaction.

Science 2019 01;363(6425):400-404

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore.

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http://www.sciencemag.org/lookup/doi/10.1126/science.aau7797
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http://dx.doi.org/10.1126/science.aau7797DOI Listing
January 2019

(Guanidine)copper Complex-Catalyzed Enantioselective Dynamic Kinetic Allylic Alkynylation under Biphasic Condition.

J Am Chem Soc 2018 07 26;140(27):8448-8455. Epub 2018 Jun 26.

Division of Chemistry and Biological Chemistry , Nanyang Technological University , 21 Nanyang Link , Singapore 637371.

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http://dx.doi.org/10.1021/jacs.7b12806DOI Listing
July 2018

Enantioselective 1,2-Anionotropic Rearrangement of Acylsilane through a Bisguanidinium Silicate Ion Pair.

J Am Chem Soc 2018 02 27;140(5):1952-1955. Epub 2018 Jan 27.

Division of Chemistry and Biological Chemistry, Nanyang Technological University , 21 Nanyang Link, Singapore 637371.

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http://pubs.acs.org/doi/10.1021/jacs.7b13056
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http://dx.doi.org/10.1021/jacs.7b13056DOI Listing
February 2018

Organocatalytic Enantioselective Protonation for Photoreduction of Activated Ketones and Ketimines Induced by Visible Light.

Angew Chem Int Ed Engl 2017 10 4;56(44):13842-13846. Epub 2017 Oct 4.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Jinming Campus, Kaifeng, Henan, 475004, P.R. China.

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http://doi.wiley.com/10.1002/anie.201707899
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http://dx.doi.org/10.1002/anie.201707899DOI Listing
October 2017

Phase-Transfer and Ion-Pairing Catalysis of Pentanidiums and Bisguanidiniums.

Acc Chem Res 2017 04 5;50(4):842-856. Epub 2017 Apr 5.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , 21 Nanyang Link, Singapore 637371.

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http://dx.doi.org/10.1021/acs.accounts.6b00604DOI Listing
April 2017

Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa.

J Med Chem 2017 01 28;60(1):215-227. Epub 2016 Dec 28.

Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University , 60 Nanyang Drive, Singapore 637551, Singapore.

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http://dx.doi.org/10.1021/acs.jmedchem.6b01025DOI Listing
January 2017

Bisguanidinium dinuclear oxodiperoxomolybdosulfate ion pair-catalyzed enantioselective sulfoxidation.

Nat Commun 2016 11 21;7:13455. Epub 2016 Nov 21.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore.

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http://dx.doi.org/10.1038/ncomms13455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121337PMC
November 2016

Highly chemo-, enantio-, and diastereoselective [4 + 2] cycloaddition of 5-thiazol-4-ones with -itaconimides.

Beilstein J Org Chem 2016 1;12:2293-2297. Epub 2016 Nov 1.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, 475004, Henan, P. R. China.

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http://www.beilstein-journals.org/bjoc/content/12/1/222
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http://dx.doi.org/10.3762/bjoc.12.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238619PMC
November 2016

Pentanidium- and Bisguanidinium-Catalyzed Enantioselective Alkylations Using Silylamide as Brønsted Probase.

J Am Chem Soc 2016 08 1;138(31):9935-40. Epub 2016 Aug 1.

Division of Chemistry and Biological Chemistry, Nanyang Technological University , 21 Nanyang Link, Singapore 637371.

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http://dx.doi.org/10.1021/jacs.6b05053DOI Listing
August 2016

Enantioselective Sulfoxidation Catalyzed by a Bisguanidinium Diphosphatobisperoxotungstate Ion Pair.

Angew Chem Int Ed Engl 2016 06 6;55(25):7101-5. Epub 2016 May 6.

Division of Chemistry and Biological Chemistry, Nanyang Technological University, 21 Nanyang Link, 637371, Singapore, Singapore.

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http://dx.doi.org/10.1002/anie.201601574DOI Listing
June 2016

Bicyclic Guanidine Catalyzed Asymmetric Tandem Isomerization Intramolecular-Diels-Alder Reaction: The First Catalytic Enantioselective Total Synthesis of (+)-alpha-Yohimbine.

Chem Asian J 2016 Feb 12;11(3):390-4. Epub 2015 Jun 12.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Science, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore.

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http://dx.doi.org/10.1002/asia.201500246DOI Listing
February 2016

Chiral Bicyclic Guanidine-Catalyzed Enantioselective Sulfenylation of Oxindoles and Benzofuran-2(3H)-ones.

J Org Chem 2015 Sep 12;80(17):8933-41. Epub 2015 Aug 12.

Institute of Chemical Biology, Henan University , Kaifeng, Henan, 475004, P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.joc.5b01606
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http://dx.doi.org/10.1021/acs.joc.5b01606DOI Listing
September 2015

Enantioselective Synthesis of Dialkylated α-Hydroxy Carboxylic Acids through Asymmetric Phase-Transfer Catalysis.

J Org Chem 2015 Aug 15;80(15):7770-8. Epub 2015 Jul 15.

†Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan 475004, P. R. China.

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http://dx.doi.org/10.1021/acs.joc.5b01081DOI Listing
August 2015

Enantioselective Synthesis of Quaternary Carbon Stereocenters: Addition of 3-Substituted Oxindoles to Vinyl Sulfone Catalyzed by Pentanidiums.

Angew Chem Int Ed Engl 2015 Aug 15;54(32):9390-3. Epub 2015 Jul 15.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore).

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http://dx.doi.org/10.1002/anie.201503844DOI Listing
August 2015

Enantioselective Oxidation of Alkenes with Potassium Permanganate Catalyzed by Chiral Dicationic Bisguanidinium.

J Am Chem Soc 2015 Aug 13;137(33):10677-82. Epub 2015 Aug 13.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , 21 Nanyang Link, Singapore, Singapore 637371.

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http://dx.doi.org/10.1021/jacs.5b05792DOI Listing
August 2015

Mechanistic insights into bicyclic guanidine-catalyzed reactions from microscopic and macroscopic perspectives.

J Org Chem 2015 Jun 22;80(11):5745-52. Epub 2015 May 22.

†Department of Chemistry and Biological Chemistry, Nanyang Technological University, 21 Nanyang Link, Singapore 637371.

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http://dx.doi.org/10.1021/acs.joc.5b00709DOI Listing
June 2015

Catalytic enantioselective alkylation of sulfenate anions to chiral heterocyclic sulfoxides using halogenated pentanidium salts.

Angew Chem Int Ed Engl 2014 Oct 10;53(44):11849-53. Epub 2014 Sep 10.

Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore).

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http://dx.doi.org/10.1002/anie.201407512DOI Listing
October 2014

Selective fluorination of alkyl C-H bonds via photocatalysis.

Chem Commun (Camb) 2014 Aug;50(60):8211-4

School of Physical & Mathematical Sciences, Division of Chemistry and Biological Chemistry, Nanyang Technological University, 21 Nanyang Link, Singapore 637371, Singapore.

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http://xlink.rsc.org/?DOI=C4CC01848F
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http://dx.doi.org/10.1039/c4cc01848fDOI Listing
August 2014

Halogen-bonding-induced hydrogen transfer to C═N bond with Hantzsch ester.

Org Lett 2014 Jun 6;16(12):3244-7. Epub 2014 Jun 6.

School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore 637371.

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http://dx.doi.org/10.1021/ol501259qDOI Listing
June 2014

Bicyclic-guanidine-catalyzed asymmetric Michael addition of 3-substituted oxindoles to 2-cyclopentenone.

Chem Asian J 2013 Dec 20;8(12):2960-4. Epub 2013 Sep 20.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan, 475004 (P. R. China), Fax: (+86) 378-2864-665.

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http://dx.doi.org/10.1002/asia.201301011DOI Listing
December 2013

Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation: direct access to pyrroloindolines and furoindolines.

Chem Commun (Camb) 2013 Oct;49(84):9854-6

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan 475004, People's Republic of China.

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http://dx.doi.org/10.1039/c3cc46111dDOI Listing
October 2013

Amphiphilic methyleneamino synthon through organic dye catalyzed-decarboxylative aminoalkylation.

Org Biomol Chem 2013 Sep;11(35):5922-5

Department of Chemistry, National University of Singapore, 3 Science, Drive 3, Singapore, 117543, Singapore.

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http://dx.doi.org/10.1039/c3ob41091aDOI Listing
September 2013

Asymmetric allylic alkylation of Morita-Baylis-Hillman carbonates with α-fluoro-β-keto esters.

Beilstein J Org Chem 2013 11;9:1853-7. Epub 2013 Sep 11.

Institute of Chemical Biology, Henan University, Jinming Campus, Kaifeng, Henan, 475004, P. R. China.

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http://dx.doi.org/10.3762/bjoc.9.216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778419PMC
September 2013

The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E(-/-) mice.

Br J Pharmacol 2013 Aug;169(8):1795-809

Key Laboratory of Cardiovascular Disease and Molecular Intervention, State Key Laboratory of Reproductive Medicine, Atherosclerosis Research Centre, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1111/bph.12246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753836PMC
August 2013

Highly enantio- and diastereoselective reactions of γ-substituted butenolides through direct vinylogous conjugate additions.

Angew Chem Int Ed Engl 2012 Oct 5;51(40):10069-73. Epub 2012 Sep 5.

Key Laboratory of Natural Medicine and Immune Engineering of Henan Province, Henan University, Jinming Campus, Kaifeng, Henan, 475004 P. R. China.

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http://dx.doi.org/10.1002/anie.201205872DOI Listing
October 2012

Graphene Oxide-Polythiophene Hybrid with Broad-Band Absorption and Photocatalytic Properties.

J Phys Chem Lett 2012 Sep 10;3(17):2332-6. Epub 2012 Aug 10.

†Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://pubs.acs.org/doi/10.1021/jz300930u
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http://dx.doi.org/10.1021/jz300930uDOI Listing
September 2012

Pentanidium-catalyzed enantioselective α-hydroxylation of oxindoles using molecular oxygen.

Org Lett 2012 Sep 4;14(18):4762-5. Epub 2012 Sep 4.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://dx.doi.org/10.1021/ol302030vDOI Listing
September 2012

Origin of asymmetric induction in bicyclic guanidine-catalyzed thio-Michael reaction: a bifunctional mode of Lewis acid-Brønsted acid activation.

J Org Chem 2012 Aug 19;77(15):6553-62. Epub 2012 Jul 19.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://dx.doi.org/10.1021/jo301158cDOI Listing
August 2012

Direct asymmetric allylic alkenylation of N-itaconimides with Morita-Baylis-Hillman carbonates.

J Org Chem 2012 Aug 26;77(15):6600-7. Epub 2012 Jul 26.

Institute of Chemical Biology, Henan University, Kaifeng, Henan, P. R. China, 475004.

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http://dx.doi.org/10.1021/jo3012539DOI Listing
August 2012

Asymmetric H-D exchange reactions of fluorinated aromatic ketones.

Chem Commun (Camb) 2012 Jun 27;48(44):5479-81. Epub 2012 Apr 27.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Republic of Singapore, 117543.

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http://dx.doi.org/10.1039/c2cc31443fDOI Listing
June 2012

Bicyclic guanidine-catalyzed asymmetric Michael additions of 3-benzyl-substituted oxindoles to N-maleimides.

Chem Commun (Camb) 2012 May 19;48(42):5124-6. Epub 2012 Apr 19.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan 475004, People's Republic of China.

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http://dx.doi.org/10.1039/c2cc31587dDOI Listing
May 2012

Catalytic diastereoselective tandem conjugate addition-elimination reaction of Morita-Baylis-Hillman C adducts by C-C bond cleavage.

Chem Asian J 2012 Apr 8;7(4):771-7. Epub 2012 Feb 8.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan, 475004 P. R. China.

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http://doi.wiley.com/10.1002/asia.201100863
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http://dx.doi.org/10.1002/asia.201100863DOI Listing
April 2012

Enantiodivergent and γ-selective asymmetric allylic amination.

Angew Chem Int Ed Engl 2012 Mar 27;51(10):2382-6. Epub 2012 Jan 27.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

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http://dx.doi.org/10.1002/anie.201107317DOI Listing
March 2012

Enantioselective organocatalytic fluorination using organofluoro nucleophiles.

Org Biomol Chem 2012 Jan 15;10(3):479-85. Epub 2011 Nov 15.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543.

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http://dx.doi.org/10.1039/c1ob05840aDOI Listing
January 2012

Galactosylated cellulosic sponge for multi-well drug safety testing.

Biomaterials 2011 Oct 8;32(29):6982-94. Epub 2011 Jul 8.

NUS Graduate School for Integrative Sciences and Engineering, Centre for Life Sciences, Singapore, Singapore.

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http://dx.doi.org/10.1016/j.biomaterials.2011.05.087DOI Listing
October 2011

Mechanistic considerations of guanidine-catalyzed reactions.

Chem Commun (Camb) 2011 Aug 4;47(29):8210-22. Epub 2011 May 4.

Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore 117543.

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http://dx.doi.org/10.1039/c0cc03691aDOI Listing
August 2011

Lewis base catalyzed enantioselective allylic hydroxylation of Morita-Baylis-Hillman carbonates with water.

J Org Chem 2011 Aug 22;76(16):6894-900. Epub 2011 Jul 22.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Kaifeng, Henan 475004, People's Republic of China.

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http://dx.doi.org/10.1021/jo201096eDOI Listing
August 2011

Air oxidation of HS(-) catalyzed by an mixed-valence diruthenium complex, an near-IR probe for HS(-) detection.

Inorg Chem 2011 Aug 19;50(16):7379-81. Epub 2011 Jul 19.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

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http://dx.doi.org/10.1021/ic201212xDOI Listing
August 2011

Highly enantio- and diastereoselective synthesis of β-methyl-γ-monofluoromethyl-substituted alcohols.

Chemistry 2011 Jul 7;17(29):8066-70. Epub 2011 Jun 7.

Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Jinming Campus, Kaifeng, Henan, 475004, PR China.

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http://doi.wiley.com/10.1002/chem.201100929
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http://dx.doi.org/10.1002/chem.201100929DOI Listing
July 2011

Expanding the utility of Brønsted base catalysis: biomimetic enantioselective decarboxylative reactions.

Chemistry 2011 Jul 15;17(30):8363-70. Epub 2011 Jun 15.

Department of Chemistry, National University of Singapore (NUS), 3 Science Drive 3, 117543, Singapore.

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http://dx.doi.org/10.1002/chem.201100687DOI Listing
July 2011

Sequential catalytic role of bifunctional bicyclic guanidine in asymmetric phospha-Michael reaction.

Org Biomol Chem 2011 Jun 20;9(12):4550-7. Epub 2011 Apr 20.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543.

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http://xlink.rsc.org/?DOI=c1ob05186e
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http://dx.doi.org/10.1039/c1ob05186eDOI Listing
June 2011

Guanidine-catalyzed enantioselective desymmetrization of meso-aziridines.

Chem Commun (Camb) 2011 Apr 21;47(13):3897-9. Epub 2011 Feb 21.

Department of Chemistry, 3 Science Drive 3, National University of Singapore (NUS), 117543 Singapore, Singapore.

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http://dx.doi.org/10.1039/c0cc05840hDOI Listing
April 2011

Pentanidium-catalyzed enantioselective phase-transfer conjugate addition reactions.

J Am Chem Soc 2011 Mar 11;133(9):2828-31. Epub 2011 Feb 11.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://dx.doi.org/10.1021/ja1098353DOI Listing
March 2011

Fluorinated aromatic ketones as nucleophiles in the asymmetric organocatalytic formation of C-C and C-N bonds: a facile route to the construction of fluorinated quaternary stereogenic centers.

Chemistry 2011 Mar 23;17(13):3571-4. Epub 2011 Feb 23.

Department of Chemistry, National University of Singapore, 3, Science Drive 3, Singapore 117543, Singapore.

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http://dx.doi.org/10.1002/chem.201003761DOI Listing
March 2011

Bicyclic guanidine-catalyzed direct asymmetric allylic addition of N-aryl alkylidene-succinimides.

Chemistry 2010 Nov;16(42):12534-7

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://dx.doi.org/10.1002/chem.201002183DOI Listing
November 2010

Rapid construction of mechanically- confined multi- cellular structures using dendrimeric intercellular linker.

Biomaterials 2010 Oct;31(29):7455-67

Department of Chemistry, Faculty of Science, National University of Singapore, S05-03-09, 3Science Drive 3, Singapore 117576, Singapore.

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http://dx.doi.org/10.1016/j.biomaterials.2010.06.020DOI Listing
October 2010

The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages.

Antioxid Redox Signal 2010 May;12(10):1147-54

Peninsula Medical School, University of Exeter, St. Luke's Campus, Exeter, Devon, England.

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http://dx.doi.org/10.1089/ars.2009.2899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875982PMC
May 2010

Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production.

J Mol Biol 2010 Feb 1;396(3):708-18. Epub 2009 Dec 1.

Department of Chemistry, National University of Singapore, Singapore.

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http://dx.doi.org/10.1016/j.jmb.2009.11.058DOI Listing
February 2010

A novel heteroleptic paddlewheel diruthenium bicyclic guanidinate complex: synthesis, structure, and scope.

Dalton Trans 2010 Jan 19;39(3):723-5. Epub 2009 Oct 19.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Singapore.

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http://dx.doi.org/10.1039/b915881bDOI Listing
January 2010

Chiral guanidinium salt catalyzed enantioselective phospha-Mannich reactions.

Angew Chem Int Ed Engl 2009 ;48(40):7387-90

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, Singapore.

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http://dx.doi.org/10.1002/anie.200903971DOI Listing
December 2009

Enantioselective protonation of itaconimides with thiols and the rotational kinetics of the axially chiral C-N bond.

Chem Asian J 2009 Nov;4(11):1741-4

Department of Chemistry, National University of Singapore (NUS), 3 Science Drive 3, Singapore.

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http://dx.doi.org/10.1002/asia.200900331DOI Listing
November 2009

GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat.

Free Radic Biol Med 2009 Jul 15;47(1):103-13. Epub 2009 Apr 15.

Pharmaceutical Science Research Division, King's College, University of London, London, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2009.04.014DOI Listing
July 2009

IF(1): setting the pace of the F(1)F(o)-ATP synthase.

Trends Biochem Sci 2009 Jul 24;34(7):343-50. Epub 2009 Jun 24.

Department of Cell and Developmental Biology, University College London, UK.

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http://dx.doi.org/10.1016/j.tibs.2009.03.006DOI Listing
July 2009

Synthesis of alpha-stereogenic amides and ketones by enantioselective conjugate addition of 1,4-dicarbonyl but-2-enes.

Chemistry 2009 ;15(19):4925-30

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore.

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http://dx.doi.org/10.1002/chem.200802601DOI Listing
June 2009

Enantioselective synthesis of chiral allenoates by guanidine-catalyzed isomerization of 3-alkynoates.

J Am Chem Soc 2009 Jun;131(21):7212-3

Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore 117543.

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http://dx.doi.org/10.1021/ja901528bDOI Listing
June 2009

Amino-indanol catalyzed enantioselective reactions of 3-hydroxy-2-pyridones.

J Am Chem Soc 2009 May;131(20):6904-5

Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore 117543.

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http://dx.doi.org/10.1021/ja900582aDOI Listing
May 2009

Chiral guanidine catalyzed enantioselective reactions.

Chem Asian J 2009 Apr;4(4):488-507

Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.

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http://dx.doi.org/10.1002/asia.200800361DOI Listing
April 2009

Anthrone-derived NHPI analogues as catalysts in reactions using oxygen as an oxidant.

Org Biomol Chem 2008 Nov 7;6(22):4096-8. Epub 2008 Oct 7.

Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore117543.

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http://xlink.rsc.org/?DOI=b812351a
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http://dx.doi.org/10.1039/b812351aDOI Listing
November 2008

Tandem conjugate addition-elimination reaction promoted by chiral pyrrolidinyl sulfonamide (CPS).

Chem Commun (Camb) 2008 Nov 24(43):5526-8. Epub 2008 Sep 24.

Department of Chemistry, National University of Singapore, Singapore.

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http://xlink.rsc.org/?DOI=b810905m
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http://dx.doi.org/10.1039/b810905mDOI Listing
November 2008

Dendrimer hydrazides as multivalent transient inter-cellular linkers.

Biomaterials 2008 Sep 12;29(27):3693-702. Epub 2008 Jun 12.

Institute of Bioengineering and Nanotechnology, A*STAR, The Nanos, #04-01, 31 Biopolis Way, Singapore 138669, Singapore.

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http://dx.doi.org/10.1016/j.biomaterials.2008.05.019DOI Listing
September 2008

Brønsted-acid and Brønsted-base catalyzed Diels-Alder reactions.

Org Biomol Chem 2008 Sep 31;6(18):3229-36. Epub 2008 Jul 31.

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://xlink.rsc.org/?DOI=b809505c
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September 2008

A gel-free 3D microfluidic cell culture system.

Biomaterials 2008 Aug 2;29(22):3237-44. Epub 2008 May 2.

Institute of Bioengineering and Nanotechnology, A*STAR, The Nanos, #04-01, 31 Biopolis Way, Singapore 138669, Singapore.

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http://dx.doi.org/10.1016/j.biomaterials.2008.04.022DOI Listing
August 2008

Enantioselective protonation catalyzed by a chiral bicyclic guanidine derivative.

Angew Chem Int Ed Engl 2008 ;47(30):5641-5

Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.

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http://dx.doi.org/10.1002/anie.200801378DOI Listing
August 2008

C3-Spacer-containing circular oligonucleotides as inhibitors of human topoisomerase I.

Bioorg Med Chem Lett 2008 Jun 4;18(12):3597-602. Epub 2008 May 4.

Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore 117543, Singapore.

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http://dx.doi.org/10.1016/j.bmcl.2008.04.076DOI Listing
June 2008

Bicyclic guanidine-catalyzed enantioselective phospha-Michael reaction: synthesis of chiral beta-aminophosphine oxides and beta-aminophosphines.

Chem Commun (Camb) 2007 Dec 1(47):5058-60. Epub 2007 Oct 1.

Department of Chemistry, 3 Science Drive 3, National University of Singapore, Singapore, 117543.

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http://dx.doi.org/10.1039/b713151hDOI Listing
December 2007

Transient inter-cellular polymeric linker.

Biomaterials 2007 Sep 3;28(25):3656-67. Epub 2007 May 3.

Institute of Biotechnology and Nanotechnology, A*STAR, The Nanos, Singapore.

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http://dx.doi.org/10.1016/j.biomaterials.2007.04.034DOI Listing
September 2007

Asymmetric Baylis-Hillman reactions promoted by chiral imidazolines.

Chem Asian J 2006 Nov;1(5):724-9

Department of Chemistry, National University of Singapore, 3, Science Drive, Singapore 117543, Singapore.

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http://dx.doi.org/10.1002/asia.200600191DOI Listing
November 2006

Chiral bicyclic guanidine-catalyzed enantioselective reactions of anthrones.

J Am Chem Soc 2006 Oct;128(42):13692-3

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.

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http://pubs.acs.org/doi/abs/10.1021/ja064636n
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October 2006

Synthesis of (+),(-)-neamine and their positional isomers as potential antibiotics.

Bioorg Med Chem Lett 2003 Mar;13(5):901-3

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 45 Shattuck Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/s0960-894x(02)01073-9DOI Listing
March 2003

Stereochemical Assignment of the C21-C38 Portion of the Desertomycin/Oasomycin Class of Natural Products by Using Universal NMR Databases: Proof.

Angew Chem Int Ed Engl 2000 Dec;39(23):4282-4284

Department of Chemistry and Chemical Biology Harvard University Cambridge, MA 02138, USA, Fax: (+1) 617-495-5150.

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http://dx.doi.org/10.1002/1521-3773(20001201)39:23<4282::AID-ANIE4282>3.0.CO;2-UDOI Listing
December 2000

Stereochemical Assignment of the C21-C38 Portion of the Desertomycin/Oasomycin Class of Natural Products by Using Universal NMR Databases: Prediction.

Angew Chem Int Ed Engl 2000 Dec;39(23):4279-4281

Department of Chemistry and Chemical Biology Harvard University Cambridge, MA 02138, USA, Fax: (+1) 617-495-5150.

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http://dx.doi.org/10.1002/1521-3773(20001201)39:23<4279::AID-ANIE4279>3.0.CO;2-RDOI Listing
December 2000