Chong-Jen Yu

Chong-Jen Yu

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Chong-Jen Yu

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Incidence of hepatitis B reactivation during epidermal growth factor receptor tyrosine kinase inhibitor treatment in non-small-cell lung cancer patients.

Eur J Cancer 2019 Aug 3;117:107-115. Epub 2019 Jul 3.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.05.032DOI Listing
August 2019

Non-small cell lung cancer harbouring non-resistant uncommon EGFR mutations: Mutation patterns, effectiveness of epidermal growth factor receptor-tyrosine kinase inhibitors and prognostic factors.

Eur J Cancer 2019 Aug 16;119:77-86. Epub 2019 Aug 16.

Division of Pulmonary Medicine, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1016/j.ejca.2019.06.025DOI Listing
August 2019

A rare epidermal growth factor receptor H773L/V774M compound mutation in advanced non-small-cell lung cancer with poor response to epidermal growth factor receptor tyrosine kinase inhibitor.

Respirol Case Rep 2019 Jul 10;7(5):e00425. Epub 2019 Apr 10.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan.

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http://dx.doi.org/10.1002/rcr2.425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456914PMC
July 2019

Dispositional mindfulness, self-compassion, and compassion from others as moderators between stress and depression in caregivers of patients with lung cancer.

Psychooncology 2019 Jul 6;28(7):1498-1505. Epub 2019 Jun 6.

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/pon.5106DOI Listing
July 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2019 Jul 12. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
July 2019

Clinical Trajectories and Causes of Death in Septic Patients with a Low APACHE II Score.

J Clin Med 2019 Jul 20;8(7). Epub 2019 Jul 20.

Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.

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http://dx.doi.org/10.3390/jcm8071064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678558PMC
July 2019

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.

Nat Commun 2019 Jul 29;10(1):3390. Epub 2019 Jul 29.

Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA.

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http://dx.doi.org/10.1038/s41467-019-11327-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662701PMC
July 2019

Atypical cells in pathology of endobronchial ultrasound-guided transbronchial biopsy of peripheral pulmonary lesions: incidence and clinical significance.

Surg Endosc 2019 Jun 10;33(6):1783-1788. Epub 2018 Sep 10.

Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd, Taipei, 100, Taiwan, Republic of China.

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http://dx.doi.org/10.1007/s00464-018-6452-1DOI Listing
June 2019

Weaning outcome of solid cancer patients requiring mechanical ventilation in the intensive care unit.

J Formos Med Assoc 2019 Jun 8;118(6):995-1004. Epub 2019 Mar 8.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan; Center of Sleep Disorder, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2019.02.007DOI Listing
June 2019

Effectiveness of Treatments for Advanced Non-Small-Cell Lung Cancer With Exon 20 Insertion Epidermal Growth Factor Receptor Mutations.

Clin Lung Cancer 2019 Jun 26. Epub 2019 Jun 26.

Department of Internal Medicine, National Taiwan University Hospital, and College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2019.06.018DOI Listing
June 2019

Clinical characteristics, treatment outcomes, and prognostic factors of pneumonia in non-HIV-infected patients.

Infect Drug Resist 2019 30;12:1457-1467. Epub 2019 May 30.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.2147/IDR.S199761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554003PMC
May 2019

Impact of prior pulmonary tuberculosis in treatment outcomes of HCAP and CAP patients in intensive care units.

J Microbiol Immunol Infect 2019 Apr 5;52(2):320-328. Epub 2018 Sep 5.

Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jmii.2018.08.012DOI Listing
April 2019

Metformin use mitigates the adverse prognostic effect of diabetes mellitus in chronic obstructive pulmonary disease.

Respir Res 2019 Apr 5;20(1):69. Epub 2019 Apr 5.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1186/s12931-019-1035-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451256PMC
April 2019

Validity of ICD9-CM codes to diagnose chronic obstructive pulmonary disease from National Health Insurance claim data in Taiwan.

Int J Chron Obstruct Pulmon Dis 2018;13:3055-3063. Epub 2018 Oct 2.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan,

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http://dx.doi.org/10.2147/COPD.S174265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174682PMC
March 2019

EGFR-Mutant SCLC Exhibits Heterogeneous Phenotypes and Resistance to Common Antineoplastic Drugs.

J Thorac Oncol 2019 Mar 3;14(3):513-526. Epub 2018 Dec 3.

Department of Internal Medicine, National Taiwan University Hospital, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183349
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http://dx.doi.org/10.1016/j.jtho.2018.11.021DOI Listing
March 2019

Consecutive Emergence of Typical Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in a Patient With Metastatic Pulmonary Squamous Cell Carcinoma.

J Oncol Pract 2019 Feb;15(2):115-118

1 National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Republic of China.

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http://dx.doi.org/10.1200/JOP.18.00536DOI Listing
February 2019

Timely diagnosis and treatment of sleep apnea reduce cardiovascular sequelae in patients with myocardial infarction.

PLoS One 2018 30;13(7):e0201493. Epub 2018 Jul 30.

Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201493PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066237PMC
January 2019

Risk of Sepsis and Mortality Among Patients With Chronic Obstructive Pulmonary Disease Treated With Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers.

Crit Care Med 2019 01;47(1):e14-e20

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.

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http://dx.doi.org/10.1097/CCM.0000000000003475DOI Listing
January 2019

IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer.

Cancers (Basel) 2019 Jan 2;11(1). Epub 2019 Jan 2.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, Taipei 10002, Taiwan.

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http://www.mdpi.com/2072-6694/11/1/36
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http://dx.doi.org/10.3390/cancers11010036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356910PMC
January 2019

Advanced physical examination training course improves medical students' confidence in physical examination.

J Formos Med Assoc 2019 Jan 3. Epub 2019 Jan 3.

Department of Internal Medicine, National Taiwan University College of Medicine, and National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2018.12.013DOI Listing
January 2019

Population-Based Cohort Study Reveals Distinct Associations Between Female Lung Cancer and Breast Cancer in Taiwan.

JCO Clin Cancer Inform 2018 12;2:1-14

Emily Pei-Ying Lin and Ching-Yao Yang, National Taiwan University Hospital; Chong-Jen Yu, K. Arnold Chan, and Pan-Chyr Yang, National Taiwan University Hospital and College of Medicine; Tzu-Pin Lu, National Taiwan University; Bo-Tsang Huang and Pan-Chyr Yang, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Ching-Heng Lin, Shih-Ni Chang, and Tzu-Hung Hsiao, Taichung Veterans General Hospital; and Shih-Ni Chang, China Medical University Hospital, Taichung, Taiwan.

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http://ascopubs.org/doi/10.1200/CCI.18.00065
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http://dx.doi.org/10.1200/CCI.18.00065DOI Listing
December 2018

Miliary Pulmonary Nodules: An Unusual Presentation of Leptospirosis.

Am J Respir Crit Care Med 2018 Nov;198(10):1334-1335

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1164/rccm.201708-1645IMDOI Listing
November 2018

National survey of ABC (A1C, blood pressure, cholesterol) of Diabetes Health Promotion Institutes in Taiwan: 2002-2018.

J Formos Med Assoc 2018 11 1;117(11):952-954. Epub 2018 Sep 1.

Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2018.08.013DOI Listing
November 2018

Treatment effectiveness and tolerability of afatinib at different doses in patients with EGFR-mutated lung adenocarcinoma: How low can we go?

Eur J Cancer 2018 11 8;103:32-40. Epub 2018 Sep 8.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ejca.2018.07.128DOI Listing
November 2018

Comparative effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on the risk of pneumonia and severe exacerbations in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2018 8;13:867-874. Epub 2018 Mar 8.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.

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http://dx.doi.org/10.2147/COPD.S158634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846309PMC
October 2018

Driver mutations of young lung adenocarcinoma patients with malignant pleural effusion.

Genes Chromosomes Cancer 2018 10 14;57(10):513-521. Epub 2018 Aug 14.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1002/gcc.22647DOI Listing
October 2018

The Impact of Sepsis on the Outcomes of COPD Patients: A Population-Based Cohort Study.

J Clin Med 2018 Oct 27;7(11). Epub 2018 Oct 27.

Medical Research Center, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City 23148, Taiwan.

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http://dx.doi.org/10.3390/jcm7110393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262552PMC
October 2018

MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema.

Am J Physiol Lung Cell Mol Physiol 2018 09 3;315(3):L432-L442. Epub 2018 May 3.

Department of Internal Medicine, National Taiwan University Hospital , Taiwan.

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http://dx.doi.org/10.1152/ajplung.00216.2017DOI Listing
September 2018

QuantiFERON-TB Gold Plus Is a More Sensitive Screening Tool than QuantiFERON-TB Gold In-Tube for Latent Tuberculosis Infection among Older Adults in Long-Term Care Facilities.

J Clin Microbiol 2018 08 26;56(8). Epub 2018 Jul 26.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

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http://dx.doi.org/10.1128/JCM.00427-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062801PMC
August 2018

Risks of Pneumonia in COPD Patients with New-Onset Atrial Fibrillation.

J Clin Med 2018 Aug 21;7(9). Epub 2018 Aug 21.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan 35053, Taiwan.

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http://dx.doi.org/10.3390/jcm7090229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162855PMC
August 2018

Impact of selective and nonselective beta-blockers on the risk of severe exacerbations in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2017 11;12:2987-2996. Epub 2017 Oct 11.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.

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https://www.dovepress.com/impact-of-selective-and-nonselecti
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http://dx.doi.org/10.2147/COPD.S145913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644571PMC
June 2018

Trajectories of caregiver burden and related factors in family caregivers of patients with lung cancer.

Psychooncology 2018 06 30;27(6):1493-1500. Epub 2018 Mar 30.

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/pon.4678DOI Listing
June 2018

Severe exacerbation and pneumonia in COPD patients treated with fixed combinations of inhaled corticosteroid and long-acting beta2 agonist.

Int J Chron Obstruct Pulmon Dis 2017 21;12:2477-2485. Epub 2017 Aug 21.

Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.2147/COPD.S139035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571846PMC
May 2018

Best Response According to RECIST During First-line EGFR-TKI Treatment Predicts Survival in EGFR Mutation-positive Non-Small-cell Lung Cancer Patients.

Clin Lung Cancer 2018 05 1;19(3):e361-e372. Epub 2018 Feb 1.

Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan; National Taiwan University Cancer Center, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2018.01.005DOI Listing
May 2018

Letter from Taiwan.

Authors:
Chong-Jen Yu

Respirology 2018 05 25;23(5):535-537. Epub 2018 Mar 25.

Department of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1111/resp.13288DOI Listing
May 2018

Interleukin 23/interleukin 17 axis activated by Mycobacterium avium complex (MAC) is attenuated in patients with MAC-lung disease.

Tuberculosis (Edinb) 2018 05 3;110:7-14. Epub 2018 Mar 3.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2018.03.001DOI Listing
May 2018

Combined effect of ERCC1 and ERCC2 polymorphisms on overall survival in non-squamous non-small-cell lung cancer patients treated with first-line pemetrexed/platinum.

Lung Cancer 2018 04 3;118:90-96. Epub 2018 Feb 3.

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.01.011DOI Listing
April 2018

Clinical characteristics of bacteraemia caused by Burkholderia cepacia complex species and antimicrobial susceptibility of the isolates in a medical centre in Taiwan.

Int J Antimicrob Agents 2018 Mar 10;51(3):357-364. Epub 2017 Jul 10.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2017.07.004DOI Listing
March 2018

Psychological distress and coping strategies among women with incurable lung cancer: a qualitative study.

Support Care Cancer 2018 Mar 10;26(3):989-996. Epub 2017 Oct 10.

Department of Internal Medicine, College of Medicine, National Taiwan University Hospital and National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s00520-017-3919-xDOI Listing
March 2018

Outcomes in patients with non-small-cell lung cancer and acquired Thr790Met mutation treated with osimertinib: a genomic study.

Lancet Respir Med 2018 02 14;6(2):107-116. Epub 2017 Dec 14.

Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132600173048
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http://dx.doi.org/10.1016/S2213-2600(17)30480-0DOI Listing
February 2018

The value of repeat radial-probe endobronchial ultrasound-guided transbronchial biopsy after initial non-diagnostic results in patients with peripheral pulmonary lesions.

BMC Pulm Med 2017 Oct 17;17(1):132. Epub 2017 Oct 17.

Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1186/s12890-017-0478-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646116PMC
October 2017

Real-World Data on Prognostic Factors for Overall Survival in EGFR Mutation-Positive Advanced Non-Small Cell Lung Cancer Patients Treated with First-Line Gefitinib.

Oncologist 2017 09 15;22(9):1075-1083. Epub 2017 May 15.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1634/theoncologist.2016-0331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599189PMC
September 2017

High incidence of fluoroquinolone resistance and effect of efflux pump inhibitors on moxifloxacin resistance among Mycobacterium tuberculosis isolates causing urinary tract infection in Taiwan.

Int J Antimicrob Agents 2017 Sep 28;50(3):491-495. Epub 2017 Jun 28.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2017.04.010DOI Listing
September 2017

Astrocyte-elevated gene-1 confers resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase expression.

Oncotarget 2017 Sep 28;8(37):61901-61916. Epub 2017 Jun 28.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.18717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617473PMC
September 2017

The association between inhaled corticosteroid and pneumonia in COPD patients: the improvement of patients' life quality with COPD in Taiwan (IMPACT) study.

Int J Chron Obstruct Pulmon Dis 2016 8;11:2775-2783. Epub 2016 Nov 8.

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University, College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.2147/COPD.S116750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108503PMC
August 2017

The identification of the TRPM8 channel on primary culture of human nasal epithelial cells and its response to cooling.

Medicine (Baltimore) 2017 Aug;96(31):e7640

aDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center bGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University cDepartment of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University dDepartment of Pediatrics, Tungs' Taichung Metro Harbor Hospital eDepartment of Otolaryngology-Head and Neck Surgery, Shuang Ho Hospital, Taipei, Taiwan, Republic of China.

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http://Insights.ovid.com/crossref?an=00005792-201708040-0001
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http://dx.doi.org/10.1097/MD.0000000000007640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626133PMC
August 2017

High Mortality in Severe Sepsis and Septic Shock Patients with Do-Not-Resuscitate Orders in East Asia.

PLoS One 2016 14;11(7):e0159501. Epub 2016 Jul 14.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159501PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944975PMC
July 2017

Clinical features of patients with bacteraemia caused by Mycobacterium avium complex species and antimicrobial susceptibility of the isolates at a medical centre in Taiwan, 2008-2014.

Int J Antimicrob Agents 2017 Jul 3;50(1):35-40. Epub 2017 May 3.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2017.02.016DOI Listing
July 2017

Coexistence of the BRAF Mutation and EGFR Exon 20 Insertion in a Patient with Lung Adenocarcinoma.

J Thorac Oncol 2017 07;12(7):e94-e95

Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jtho.2017.03.004DOI Listing
July 2017

Gefitinib or erlotinib in previously treated non-small-cell lung cancer patients: a cohort study in Taiwan.

Cancer Med 2017 Jul 22;6(7):1563-1572. Epub 2017 Jun 22.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1002/cam4.1121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504326PMC
July 2017

Lung adenocarcinoma patients of young age have lower mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors.

ERJ Open Res 2017 Jul 12;3(3). Epub 2017 Jul 12.

Dept of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taiwan.

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http://dx.doi.org/10.1183/23120541.00092-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507146PMC
July 2017

Outcomes of cancer therapy administered to treatment-naïve lung cancer patients in the intensive care unit.

J Cancer 2017 5;8(11):1995-2003. Epub 2017 Jul 5.

Department of Internal Medicine, National Taiwan University Hospital, No.7, Zhongshan South Road, Taipei 100, Taiwan (ROC).

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http://dx.doi.org/10.7150/jca.18178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559960PMC
July 2017

Expression of Notch Gene and Its Impact on Survival of Patients with Resectable Non-small Cell Lung Cancer.

J Cancer 2017 11;8(7):1292-1300. Epub 2017 May 11.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.7150/jca.17741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463445PMC
May 2017

Diabetes mellitus in patients with chronic obstructive pulmonary disease-The impact on mortality.

PLoS One 2017 14;12(4):e0175794. Epub 2017 Apr 14.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0175794PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391945PMC
April 2017

Preadmission tracheostomy is associated with better outcomes in patients with prolonged mechanical ventilation in the postintensive care respiratory care setting.

J Formos Med Assoc 2017 Mar 9;116(3):169-176. Epub 2016 Jul 9.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2016.05.005DOI Listing
March 2017

Acquired BRAF V600E Mutation as Resistant Mechanism after Treatment with Osimertinib.

J Thorac Oncol 2017 03 5;12(3):567-572. Epub 2016 Dec 5.

Department of Oncology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Republic of China; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.11.2231DOI Listing
March 2017

Diabetes Mellitus and Latent Tuberculosis Infection: A Systematic Review and Metaanalysis.

Clin Infect Dis 2017 03;64(6):719-727

Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taiwan.

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http://dx.doi.org/10.1093/cid/ciw836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399944PMC
March 2017

Predictive factors for EGFR-tyrosine kinase inhibitor retreatment in patients with EGFR-mutated non-small-cell lung cancer - A multicenter retrospective SEQUENCE study.

Lung Cancer 2017 02 14;104:58-64. Epub 2016 Dec 14.

Department of Chest Medicine, Taipei AVeterans General Hospital, School of Medicine, National Yang-Ming Medical University, and School of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.12.002DOI Listing
February 2017

Transthoracic Ultrasound Elastography in Pulmonary Lesions and Diseases.

Ultrasound Med Biol 2017 01 12;43(1):145-152. Epub 2016 Oct 12.

Department of Internal Medicine, Division of Chest Medicine, National Taiwan University Hospital, Taipei City, Taiwan; Department of Internal Medicine, School of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2016.08.028DOI Listing
January 2017

Evaluation of the automated Becton Dickinson MAX real-time PCR platform for detection of Pneumocystis jirovecii.

Future Microbiol 2017 01 12;12:29-37. Epub 2016 Dec 12.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

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https://www.futuremedicine.com/doi/10.2217/fmb-2016-0115
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http://dx.doi.org/10.2217/fmb-2016-0115DOI Listing
January 2017

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

Authors:
Wei Jie Seow Keitaro Matsuo Chao Agnes Hsiung Kouya Shiraishi Minsun Song Hee Nam Kim Maria Pik Wong Yun-Chul Hong H Dean Hosgood Zhaoming Wang I-Shou Chang Jiu-Cun Wang Nilanjan Chatterjee Margaret Tucker Hu Wei Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Baosen Zhou Neil E Caporaso Demetrius Albanes Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Xiao-Ou Shu Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Michiaki Kubo Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Hiroshi Nokihara Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Zhihua Yin Jianxin Shi Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Tangchun Wu Fusheng Wei Jason Y Y Wong Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Victor Ho Fun Lee Wu-Chou Su Yuh-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Pan-Chyr Yang Hsien-Chih Lin Yong-Bing Xiang Adeline Seow Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Haixin Li Yu-Tang Gao Chen Wu Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Charles Lawrence Laurie Burdett Meredith Yeager Kevin B Jacobs Amy Hutchinson Sonja I Berndt Xingzhou He Wei Wu Junwen Wang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu Chang Hyun Kang Lingmin Hu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Alan Dart Loon Sihoe Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho-Il Yoon Qiuyin Cai Chien-Chung Lin In Kyu Park Ping Xu Jing Dong Christopher Kim Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen John K C Chan Minjie Chu Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Yen-Li Lo Ying-Hsiang Chen Joseph F Fraumeni Jie Liu Taiki Yamaji Yang Yang Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Gening Jiang Ke Fei Guoping Wu Li-Hsin Chien Hui-Ling Chen Yu-Chun Su Fang-Yu Tsai Yi-Song Chen Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Dongxin Lin Kexin Chen Yi-Long Wu Maria Teresa Landi Hongbing Shen Nathaniel Rothman Takashi Kohno Stephen J Chanock Qing Lan

Hum Mol Genet 2017 01;26(2):454-465

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddw414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856088PMC
January 2017

Rapid Sputum Multiplex Detection of the M. tuberculosis Complex (MTBC) and Resistance Mutations for Eight Antibiotics by Nucleotide MALDI-TOF MS.

Sci Rep 2017 01 30;7:41486. Epub 2017 Jan 30.

Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1038/srep41486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278408PMC
January 2017

Inhaled nitric oxide and the risk of renal dysfunction in patients with acute respiratory distress syndrome: a propensity-matched cohort study.

Crit Care 2016 Nov 30;20(1):389. Epub 2016 Nov 30.

Institute of Epidemiology and Preventive Medicine, National Taiwan University, No.17 Xu-Zhou Road, Taipei, 10020, Taiwan.

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http://dx.doi.org/10.1186/s13054-016-1566-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131425PMC
November 2016

The Role of PIK3CA Mutations among Lung Adenocarcinoma Patients with Primary and Acquired Resistance to EGFR Tyrosine Kinase Inhibition.

Sci Rep 2016 10 13;6:35249. Epub 2016 Oct 13.

Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1038/srep35249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062358PMC
October 2016

Current advances of endobronchial ultrasonography in the diagnosis and staging of lung cancer.

J Thorac Dis 2016 Oct;8(Suppl 9):S690-S696

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.21037/jtd.2016.08.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179348PMC
October 2016

Anaplastic Lymphoma Kinase (ALK) Kinase Domain Mutation Following ALK Inhibitor(s) Failure in Advanced ALK Positive Non-Small-Cell Lung Cancer: Analysis and Literature Review.

Clin Lung Cancer 2016 09 30;17(5):e77-e94. Epub 2016 Mar 30.

Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.03.005DOI Listing
September 2016

Moxifloxacin Improves Treatment Outcomes in Patients with Ofloxacin-Resistant Multidrug-Resistant Tuberculosis.

Antimicrob Agents Chemother 2016 08 22;60(8):4708-16. Epub 2016 Jul 22.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

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http://dx.doi.org/10.1128/AAC.00425-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958188PMC
August 2016

Factors responsible for poor sleep quality in patients with chronic obstructive pulmonary disease.

BMC Pulm Med 2016 08 8;16(1):118. Epub 2016 Aug 8.

Department of Pulmonary and Critical Care Medicine, Linkou Chang-Gung Memorial Hospital, Chang-Gung medical foundation, Taoyuan, Taiwan.

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http://dx.doi.org/10.1186/s12890-016-0281-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977946PMC
August 2016

Identification of nontuberculous mycobacteria in MGIT by matrix-assisted laser desorption/ionization mass spectrometry.

Future Microbiol 2016 08 9;11:1025-33. Epub 2016 Aug 9.

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.2217/fmb.16.20DOI Listing
August 2016

Influence of patient and provider factors on the workload of on-call physicians: A general internal medicine cohort observational study.

Medicine (Baltimore) 2016 Aug;95(35):e4719

aDivision of Hospital Medicine bDepartment of Internal Medicine cDepartment of Traumatology dCenter of Quality Management eDepartment of Surgery, National Taiwan University Hospital fInstitute of Health Policy and Management, College of Public Health, National Taiwan University gDepartment of Orthopedics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

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http://dx.doi.org/10.1097/MD.0000000000004719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008594PMC
August 2016

Risk of Tuberculosis Among Patients on Dialysis: The Predictive Value of Serial Interferon-Gamma Release Assay.

Medicine (Baltimore) 2016 May;95(22):e3813

From the Graduate Institute of Clinical Medicine (C-CS), College of Medicine, National Taiwan University; Department of Traumatology (C-CS, J-SC); Department of Internal Medicine (C-CS, C-LH, V-CW, J-YW, C-JY, L-NL), National Taiwan University Hospital, Taipei City; Department of Internal Medicine (Y-FW), E-Da Hospital, Kaohsiung City; Department of Surgery (C-YL, J-SC), National Taiwan University Hospital, Taipei City; Division of Nephrology (H-HL), Department of Internal Medicine, Hsin-Jen Hospital, New Taipei City; Department of Internal Medicine (F-JY), National Taiwan University Hospital, Yun-Lin branch, Yun-Lin County; College of Public Health (H-HL), National Taiwan University; and Department of Laboratory Medicine (L-NL), National Taiwan University Hospital, Taipei City, Taipei, Taiwan.

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http://dx.doi.org/10.1097/MD.0000000000003813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900731PMC
May 2016