Publications by authors named "Chong-Jen Yu"

100Publications

Matrix Metalloprotease-7 Mediates Nucleolar Assembly and Intra-nucleolar Cleaving p53 in Gefitinib-Resistant Cancer Stem Cells.

iScience 2020 Oct 23;23(10):101600. Epub 2020 Sep 23.

Department of Internal Medicine, National Taiwan University Hospital, Taipei 10048, Taiwan.

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http://dx.doi.org/10.1016/j.isci.2020.101600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559243PMC
October 2020

Usefulness of Xpert MTB/RIF Ultra to Rapidly Diagnose Sputum Smear-Negative Pulmonary Tuberculosis Using Bronchial Washing Fluid.

Front Microbiol 2020 22;11:588963. Epub 2020 Sep 22.

Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.3389/fmicb.2020.588963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536285PMC
September 2020

Trait mindfulness and depressive symptoms in non-small cell lung cancer patients: the mediating roles of quality of life and meaning in life.

Psychol Health 2020 Sep 30:1-13. Epub 2020 Sep 30.

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1080/08870446.2020.1825713DOI Listing
September 2020

Risk of active tuberculosis among COPD patients treated with fixed combinations of long-acting beta2 agonists and inhaled corticosteroids.

BMC Infect Dis 2020 Sep 25;20(1):706. Epub 2020 Sep 25.

Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1186/s12879-020-05440-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7519522PMC
September 2020

Osimertinib in Resected -Mutated Non-Small-Cell Lung Cancer.

N Engl J Med 2020 Sep 19. Epub 2020 Sep 19.

From the Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, and Guangdong Academy of Medical Sciences, Guangzhou (Y.-L.W.), the Thoracic Surgery Department, National Cancer Center-National Clinical Research Center for Cancer-Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (J.H.), and the Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai (S.L.) - all in China; the Department of Thoracic Surgery and Oncology, National Cancer Center Hospital East, Kashiwa (M.T.), and the Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama (T.K.) - both in Japan; the Department of Medical Oncology, Austin Health, Melbourne, VIC, Australia (T.J.); the Department of Respiratory Diseases, Evangelische Lungenklinik, Berlin (C.G.); the Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona (M.M.), and the Department of Oncology, Hospital Universitario Fundación Jiménez Díaz, Madrid (M.D.); the David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles (J.W.G.); the Center of Innovative Technologies and Oncology, N.N. Blokhin Russian Cancer Center, Russian Academy of Medical Sciences, Moscow (K.L.); the Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine (S.-W.K.), and the Precision Medicine Lung Cancer Center, Konkuk University Medical Center (K.-Y.L.) - both in Seoul, South Korea; the Department of Thoracic Surgery, Cho Ray Hospital, Ho Chi Minh City, Vietnam (H.-V.V.); the Division of Medical Oncology, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand (C.A.); the Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (C.-J.Y.); the Division of Thoracic Oncology, European Institute of Oncology, IRCCS, Milan (F.M.), and Medical Oncology 2, Istituto Oncologico Veneto, IRCCS, Padua (L.B.) - both in Italy; the Department of Medical Oncology and Hematology, University Health Network, Princess Margaret Cancer Centre and the University of Toronto, Toronto (F.A.S.); Late Oncology Statistics, AstraZeneca, Gaithersburg, MD (L.Z.); Late Oncology Statistics (R.H.) and Oncology Research and Development (A.A., Y.R.), AstraZeneca, Cambridge, United Kingdom; and Section of Medical Oncology, Yale School of Medicine and Yale Cancer Center, New Haven, CT (R.S.H.).

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http://dx.doi.org/10.1056/NEJMoa2027071DOI Listing
September 2020

The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Ther Adv Med Oncol 2020 10;12:1758835920946156. Epub 2020 Aug 10.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei 100.

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http://dx.doi.org/10.1177/1758835920946156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418472PMC
August 2020

Clinical course and risk factors of mortality in Mycobacterium avium complex lung disease without initial treatment.

Respir Med 2020 Sep 25;171:106070. Epub 2020 Jun 25.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan; College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.rmed.2020.106070DOI Listing
September 2020

Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma.

EBioMedicine 2020 Jul 3;57:102846. Epub 2020 Jul 3.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Zhongshan S Rd, Zhongzheng District, Taipei 10002, Taiwan; Graduate Institute of Toxicology, College of Medicine, National Taiwan University, No. 1, Jen Ai Rd, Section 1, Zhongzheng District, Taipei 10051, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339020PMC
July 2020

Pulmonary pleomorphic carcinoma with pembrolizumab monotherapy.

Respirol Case Rep 2020 Aug 12;8(6):e0597. Epub 2020 Jun 12.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan.

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http://dx.doi.org/10.1002/rcr2.597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7290282PMC
August 2020

Different clinical features of patients with pulmonary disease caused by various Mycobacterium avium-intracellulare complex subspecies and antimicrobial susceptibility.

Int J Infect Dis 2020 Sep 10;98:33-40. Epub 2020 Jun 10.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2020.06.019DOI Listing
September 2020

Autophagy in fibroblasts induced by cigarette smoke extract promotes invasion in lung cancer cells.

Int J Cancer 2020 Jun 3. Epub 2020 Jun 3.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1002/ijc.33127DOI Listing
June 2020

Complex EGFR mutations with secondary T790M mutation confer shorter osimertinib progression-free survival and overall survival in advanced non-small cell lung cancer.

Lung Cancer 2020 07 30;145:1-9. Epub 2020 Apr 30.

Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, No. 7, Zhongshan South Road, Taipei 100, Taiwan; Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2020.04.022DOI Listing
July 2020

Inappropriate Peak Inspiratory Flow Rate with Dry Powder Inhaler in Chronic Obstructive Pulmonary Disease.

Sci Rep 2020 04 29;10(1):7271. Epub 2020 Apr 29.

Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1038/s41598-020-64235-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190738PMC
April 2020

Clinical outcomes and toxicity predictors of thoracic re-irradiation for locoregionally recurrent lung cancer.

Clin Transl Radiat Oncol 2020 May 23;22:76-82. Epub 2020 Mar 23.

Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ctro.2020.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139144PMC
May 2020

The impact on incident tuberculosis by kidney function impairment status: analysis of severity relationship.

Respir Res 2020 Feb 12;21(1):51. Epub 2020 Feb 12.

Department of Internal Medicine, National Taiwan University Hospital, NO 7, Chung-Shan South Road, Taipei, Taiwan, 100, Taiwan.

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http://dx.doi.org/10.1186/s12931-020-1294-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017479PMC
February 2020

Clinical features and treatment outcomes of Mycobacterium chimaera lung disease and antimicrobial susceptibility of the mycobacterial isolates.

J Infect 2020 Apr 17;80(4):437-443. Epub 2020 Jan 17.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2020.01.005DOI Listing
April 2020

Clinical factors associated with treatment toxicity of pemetrexed plus platinum in elderly patients with non-small cell lung cancer.

J Formos Med Assoc 2020 Oct 6;119(10):1506-1513. Epub 2020 Jan 6.

Division of Pulmonary Medicine, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2019.12.007DOI Listing
October 2020

Predictive Modelling of Lung Function using Emphysematous Density Distribution.

Sci Rep 2019 12 24;9(1):19763. Epub 2019 Dec 24.

Department of Biomedical Engineering, National Taiwan University, No. 1, Sec. 1, Jen - Ai Rd., Taipei City, 100, Taiwan (R.O.C.).

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http://dx.doi.org/10.1038/s41598-019-56351-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930211PMC
December 2019

Major comorbidities lead to the risk of adverse cardiovascular events in chronic obstructive pulmonary disease patients using inhaled long-acting bronchodilators: a case-control study.

BMC Pulm Med 2019 Dec 3;19(1):233. Epub 2019 Dec 3.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1186/s12890-019-0999-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889444PMC
December 2019

Radial endobronchial ultrasound-guided transbronchial biopsy for peripheral pulmonary malignancy: biopsy- or brushing-first?

BMC Pulm Med 2019 Oct 31;19(1):193. Epub 2019 Oct 31.

Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1186/s12890-019-0961-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823946PMC
October 2019

Clinical factors associated with treatment outcomes in EGFR mutant non-small cell lung cancer patients with brain metastases: a case-control observational study.

BMC Cancer 2019 Oct 26;19(1):1006. Epub 2019 Oct 26.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, No.7, Chung Shan S. Rd., Taipei City, 100, Taiwan, Republic of China.

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http://dx.doi.org/10.1186/s12885-019-6140-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815404PMC
October 2019

Anidulafungin as an alternative treatment for Pneumocystis jirovecii pneumonia in patients who cannot tolerate trimethoprim/sulfamethoxazole.

Int J Antimicrob Agents 2020 Jan 14;55(1):105820. Epub 2019 Oct 14.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7 Chung-Shan S. Road, Taipei 100, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No. 7 Chung-Shan S. Road, Taipei 100, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2019.10.001DOI Listing
January 2020

Prognostic value of the mitogen response in the interferon-γ release assay in patients with culture-confirmed tuberculosis.

Respir Med 2019 Oct - Nov;158:49-54. Epub 2019 Oct 7.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.rmed.2019.10.004DOI Listing
August 2020

Author reply to Letter to Editor "Weaning outcome of solid cancer patients requiring mechanical ventilation in the ICU: Other factors to explore".

J Formos Med Assoc 2019 12 17;118(12):1678-1679. Epub 2019 Sep 17.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2019.09.002DOI Listing
December 2019

Risk of sepsis among patients with COPD treated with fixed combinations of inhaled corticosteroids and long-acting Beta2 agonists.

Aging (Albany NY) 2019 09 10;11(17):6863-6871. Epub 2019 Sep 10.

Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/aging.102217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756880PMC
September 2019

Non-small cell lung cancer harbouring non-resistant uncommon EGFR mutations: Mutation patterns, effectiveness of epidermal growth factor receptor-tyrosine kinase inhibitors and prognostic factors.

Eur J Cancer 2019 09 16;119:77-86. Epub 2019 Aug 16.

Division of Pulmonary Medicine, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1016/j.ejca.2019.06.025DOI Listing
September 2019

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.

Nat Commun 2019 07 29;10(1):3390. Epub 2019 Jul 29.

Division of Pulmonary and Critical Care Medicine, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, 10021, USA.

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http://dx.doi.org/10.1038/s41467-019-11327-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662701PMC
July 2019

Clinical Trajectories and Causes of Death in Septic Patients with a Low APACHE II Score.

J Clin Med 2019 Jul 20;8(7). Epub 2019 Jul 20.

Department of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.

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http://dx.doi.org/10.3390/jcm8071064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678558PMC
July 2019

Effectiveness of Treatments for Advanced Non-Small-Cell Lung Cancer With Exon 20 Insertion Epidermal Growth Factor Receptor Mutations.

Clin Lung Cancer 2019 11 26;20(6):e620-e630. Epub 2019 Jun 26.

Department of Internal Medicine, National Taiwan University Hospital, and College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2019.06.018DOI Listing
November 2019

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women.

Authors:
Jason Y Y Wong Han Zhang Chao A Hsiung Kouya Shiraishi Kai Yu Keitaro Matsuo Maria Pik Wong Yun-Chul Hong Jiucun Wang Wei Jie Seow Zhaoming Wang Minsun Song Hee Nam Kim I-Shou Chang Nilanjan Chatterjee Wei Hu Chen Wu Tetsuya Mitsudomi Wei Zheng Jin Hee Kim Adeline Seow Neil E Caporaso Min-Ho Shin Lap Ping Chung She-Juan An Ping Wang Yang Yang Hong Zheng Yasushi Yatabe Xu-Chao Zhang Young Tae Kim Qiuyin Cai Zhihua Yin Young-Chul Kim Bryan A Bassig Jiang Chang James Chung Man Ho Bu-Tian Ji Yataro Daigo Hidemi Ito Yukihide Momozawa Kyota Ashikawa Yoichiro Kamatani Takayuki Honda H Dean Hosgood Hiromi Sakamoto Hideo Kunitoh Koji Tsuta Shun-Ichi Watanabe Michiaki Kubo Yohei Miyagi Haruhiko Nakayama Shingo Matsumoto Masahiro Tsuboi Koichi Goto Jianxin Shi Lei Song Xing Hua Atsushi Takahashi Akiteru Goto Yoshihiro Minamiya Kimihiro Shimizu Kazumi Tanaka Fusheng Wei Fumihiko Matsuda Jian Su Yeul Hong Kim In-Jae Oh Fengju Song Wu-Chou Su Yu-Min Chen Gee-Chen Chang Kuan-Yu Chen Ming-Shyan Huang Li-Hsin Chien Yong-Bing Xiang Jae Yong Park Sun-Seog Kweon Chien-Jen Chen Kyoung-Mu Lee Batel Blechter Haixin Li Yu-Tang Gao Biyun Qian Daru Lu Jianjun Liu Hyo-Sung Jeon Chin-Fu Hsiao Jae Sook Sung Ying-Huang Tsai Yoo Jin Jung Huan Guo Zhibin Hu Wen-Chang Wang Charles C Chung Laurie Burdett Meredith Yeager Amy Hutchinson Sonja I Berndt Wei Wu Herbert Pang Yuqing Li Jin Eun Choi Kyong Hwa Park Sook Whan Sung Li Liu C H Kang Meng Zhu Chung-Hsing Chen Tsung-Ying Yang Jun Xu Peng Guan Wen Tan Chih-Liang Wang Michael Hsin Ko-Yung Sit James Ho Ying Chen Yi Young Choi Jen-Yu Hung Jun Suk Kim Ho Il Yoon Chien-Chung Lin In Kyu Park Ping Xu Yuzhuo Wang Qincheng He Reury-Perng Perng Chih-Yi Chen Roel Vermeulen Junjie Wu Wei-Yen Lim Kun-Chieh Chen Yao-Jen Li Jihua Li Hongyan Chen Chong-Jen Yu Li Jin Tzu-Yu Chen Shih-Sheng Jiang Jie Liu Taiki Yamaji Belynda Hicks Kathleen Wyatt Shengchao A Li Juncheng Dai Hongxia Ma Guangfu Jin Bao Song Zhehai Wang Sensen Cheng Xuelian Li Yangwu Ren Ping Cui Motoki Iwasaki Taichi Shimazu Shoichiro Tsugane Junjie Zhu Ying Chen Kaiyun Yang Gening Jiang Ke Fei Guoping Wu Hsien-Chin Lin Hui-Ling Chen Yao-Huei Fang Fang-Yu Tsai Wan-Shan Hsieh Jinming Yu Victoria L Stevens Ite A Laird-Offringa Crystal N Marconett Linda Rieswijk Ann Chao Pan-Chyr Yang Xiao-Ou Shu Tangchun Wu Y L Wu Dongxin Lin Kexin Chen Baosen Zhou Yun-Chao Huang Takashi Kohno Hongbing Shen Stephen J Chanock Nathaniel Rothman Qing Lan

Genomics 2020 03 12;112(2):1223-1232. Epub 2019 Jul 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ygeno.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954985PMC
March 2020

Incidence of hepatitis B reactivation during epidermal growth factor receptor tyrosine kinase inhibitor treatment in non-small-cell lung cancer patients.

Eur J Cancer 2019 08 3;117:107-115. Epub 2019 Jul 3.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2019.05.032DOI Listing
August 2019

Clinical characteristics, treatment outcomes, and prognostic factors of pneumonia in non-HIV-infected patients.

Infect Drug Resist 2019 30;12:1457-1467. Epub 2019 May 30.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.2147/IDR.S199761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554003PMC
May 2019

Two-month breathing-based walking improves anxiety, depression, dyspnoea and quality of life in chronic obstructive pulmonary disease: A randomised controlled study.

J Clin Nurs 2019 Oct 28;28(19-20):3632-3640. Epub 2019 Jun 28.

Department of Renal Care, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.

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http://dx.doi.org/10.1111/jocn.14960DOI Listing
October 2019

Dispositional mindfulness, self-compassion, and compassion from others as moderators between stress and depression in caregivers of patients with lung cancer.

Psychooncology 2019 07 6;28(7):1498-1505. Epub 2019 Jun 6.

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/pon.5106DOI Listing
July 2019

A rare epidermal growth factor receptor H773L/V774M compound mutation in advanced non-small-cell lung cancer with poor response to epidermal growth factor receptor tyrosine kinase inhibitor.

Respirol Case Rep 2019 Jul 10;7(5):e00425. Epub 2019 Apr 10.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine National Taiwan University Hospital Taipei Taiwan.

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http://dx.doi.org/10.1002/rcr2.425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456914PMC
July 2019

Metformin use mitigates the adverse prognostic effect of diabetes mellitus in chronic obstructive pulmonary disease.

Respir Res 2019 Apr 5;20(1):69. Epub 2019 Apr 5.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1186/s12931-019-1035-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451256PMC
April 2019

Weaning outcome of solid cancer patients requiring mechanical ventilation in the intensive care unit.

J Formos Med Assoc 2019 Jun 8;118(6):995-1004. Epub 2019 Mar 8.

Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan; Center of Sleep Disorder, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2019.02.007DOI Listing
June 2019

Consecutive Emergence of Typical Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in a Patient With Metastatic Pulmonary Squamous Cell Carcinoma.

J Oncol Pract 2019 02;15(2):115-118

1 National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Republic of China.

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http://dx.doi.org/10.1200/JOP.18.00536DOI Listing
February 2019

Population-Based Cohort Study Reveals Distinct Associations Between Female Lung Cancer and Breast Cancer in Taiwan.

JCO Clin Cancer Inform 2018 12;2:1-14

Emily Pei-Ying Lin and Ching-Yao Yang, National Taiwan University Hospital; Chong-Jen Yu, K. Arnold Chan, and Pan-Chyr Yang, National Taiwan University Hospital and College of Medicine; Tzu-Pin Lu, National Taiwan University; Bo-Tsang Huang and Pan-Chyr Yang, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Ching-Heng Lin, Shih-Ni Chang, and Tzu-Hung Hsiao, Taichung Veterans General Hospital; and Shih-Ni Chang, China Medical University Hospital, Taichung, Taiwan.

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http://ascopubs.org/doi/10.1200/CCI.18.00065
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http://dx.doi.org/10.1200/CCI.18.00065DOI Listing
December 2018

Advanced physical examination training course improves medical students' confidence in physical examination.

J Formos Med Assoc 2019 Oct 3;118(10):1416-1422. Epub 2019 Jan 3.

Department of Internal Medicine, National Taiwan University College of Medicine, and National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jfma.2018.12.013DOI Listing
October 2019

IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer.

Cancers (Basel) 2019 Jan 2;11(1). Epub 2019 Jan 2.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University, Taipei 10002, Taiwan.

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http://www.mdpi.com/2072-6694/11/1/36
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http://dx.doi.org/10.3390/cancers11010036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356910PMC
January 2019

EGFR-Mutant SCLC Exhibits Heterogeneous Phenotypes and Resistance to Common Antineoplastic Drugs.

J Thorac Oncol 2019 03 3;14(3):513-526. Epub 2018 Dec 3.

Department of Internal Medicine, National Taiwan University Hospital, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15560864183349
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http://dx.doi.org/10.1016/j.jtho.2018.11.021DOI Listing
March 2019

The Impact of Sepsis on the Outcomes of COPD Patients: A Population-Based Cohort Study.

J Clin Med 2018 Oct 27;7(11). Epub 2018 Oct 27.

Medical Research Center, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City 23148, Taiwan.

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http://dx.doi.org/10.3390/jcm7110393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262552PMC
October 2018

Validity of ICD9-CM codes to diagnose chronic obstructive pulmonary disease from National Health Insurance claim data in Taiwan.

Int J Chron Obstruct Pulmon Dis 2018;13:3055-3063. Epub 2018 Oct 2.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan,

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http://dx.doi.org/10.2147/COPD.S174265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174682PMC
March 2019

Risk of Sepsis and Mortality Among Patients With Chronic Obstructive Pulmonary Disease Treated With Angiotensin-Converting Enzyme Inhibitors or Angiotensin Receptor Blockers.

Crit Care Med 2019 01;47(1):e14-e20

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.

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http://dx.doi.org/10.1097/CCM.0000000000003475DOI Listing
January 2019

Impact of prior pulmonary tuberculosis in treatment outcomes of HCAP and CAP patients in intensive care units.

J Microbiol Immunol Infect 2019 Apr 5;52(2):320-328. Epub 2018 Sep 5.

Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jmii.2018.08.012DOI Listing
April 2019

Atypical cells in pathology of endobronchial ultrasound-guided transbronchial biopsy of peripheral pulmonary lesions: incidence and clinical significance.

Surg Endosc 2019 06 10;33(6):1783-1788. Epub 2018 Sep 10.

Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd, Taipei, 100, Taiwan, Republic of China.

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http://dx.doi.org/10.1007/s00464-018-6452-1DOI Listing
June 2019

Treatment effectiveness and tolerability of afatinib at different doses in patients with EGFR-mutated lung adenocarcinoma: How low can we go?

Eur J Cancer 2018 11 8;103:32-40. Epub 2018 Sep 8.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.ejca.2018.07.128DOI Listing
November 2018

National survey of ABC (A1C, blood pressure, cholesterol) of Diabetes Health Promotion Institutes in Taiwan: 2002-2018.

J Formos Med Assoc 2018 11 1;117(11):952-954. Epub 2018 Sep 1.

Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jfma.2018.08.013DOI Listing
November 2018

Risks of Pneumonia in COPD Patients with New-Onset Atrial Fibrillation.

J Clin Med 2018 Aug 21;7(9). Epub 2018 Aug 21.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan 35053, Taiwan.

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http://dx.doi.org/10.3390/jcm7090229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162855PMC
August 2018

Driver mutations of young lung adenocarcinoma patients with malignant pleural effusion.

Genes Chromosomes Cancer 2018 10 14;57(10):513-521. Epub 2018 Aug 14.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1002/gcc.22647DOI Listing
October 2018

Miliary Pulmonary Nodules: An Unusual Presentation of Leptospirosis.

Am J Respir Crit Care Med 2018 11;198(10):1334-1335

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1164/rccm.201708-1645IMDOI Listing
November 2018

Timely diagnosis and treatment of sleep apnea reduce cardiovascular sequelae in patients with myocardial infarction.

PLoS One 2018 30;13(7):e0201493. Epub 2018 Jul 30.

Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201493PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066237PMC
January 2019

QuantiFERON-TB Gold Plus Is a More Sensitive Screening Tool than QuantiFERON-TB Gold In-Tube for Latent Tuberculosis Infection among Older Adults in Long-Term Care Facilities.

J Clin Microbiol 2018 08 26;56(8). Epub 2018 Jul 26.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

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http://dx.doi.org/10.1128/JCM.00427-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062801PMC
August 2018

Interleukin 23/interleukin 17 axis activated by Mycobacterium avium complex (MAC) is attenuated in patients with MAC-lung disease.

Tuberculosis (Edinb) 2018 05 3;110:7-14. Epub 2018 Mar 3.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2018.03.001DOI Listing
May 2018

MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema.

Am J Physiol Lung Cell Mol Physiol 2018 09 3;315(3):L432-L442. Epub 2018 May 3.

Department of Internal Medicine, National Taiwan University Hospital , Taiwan.

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http://dx.doi.org/10.1152/ajplung.00216.2017DOI Listing
September 2018

Letter from Taiwan.

Authors:
Chong-Jen Yu

Respirology 2018 05 25;23(5):535-537. Epub 2018 Mar 25.

Department of Medicine, National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1111/resp.13288DOI Listing
May 2018

Combined effect of ERCC1 and ERCC2 polymorphisms on overall survival in non-squamous non-small-cell lung cancer patients treated with first-line pemetrexed/platinum.

Lung Cancer 2018 04 3;118:90-96. Epub 2018 Feb 3.

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2018.01.011DOI Listing
April 2018

Comparative effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on the risk of pneumonia and severe exacerbations in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2018 8;13:867-874. Epub 2018 Mar 8.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.

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http://dx.doi.org/10.2147/COPD.S158634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846309PMC
October 2018

Best Response According to RECIST During First-line EGFR-TKI Treatment Predicts Survival in EGFR Mutation-positive Non-Small-cell Lung Cancer Patients.

Clin Lung Cancer 2018 05 1;19(3):e361-e372. Epub 2018 Feb 1.

Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan; National Taiwan University Cancer Center, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2018.01.005DOI Listing
May 2018

Trajectories of caregiver burden and related factors in family caregivers of patients with lung cancer.

Psychooncology 2018 06 30;27(6):1493-1500. Epub 2018 Mar 30.

School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1002/pon.4678DOI Listing
June 2018

Outcomes in patients with non-small-cell lung cancer and acquired Thr790Met mutation treated with osimertinib: a genomic study.

Lancet Respir Med 2018 02 14;6(2):107-116. Epub 2017 Dec 14.

Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132600173048
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http://dx.doi.org/10.1016/S2213-2600(17)30480-0DOI Listing
February 2018

Impact of selective and nonselective beta-blockers on the risk of severe exacerbations in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2017 11;12:2987-2996. Epub 2017 Oct 11.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.

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https://www.dovepress.com/impact-of-selective-and-nonselecti
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http://dx.doi.org/10.2147/COPD.S145913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644571PMC
June 2018

The value of repeat radial-probe endobronchial ultrasound-guided transbronchial biopsy after initial non-diagnostic results in patients with peripheral pulmonary lesions.

BMC Pulm Med 2017 Oct 17;17(1):132. Epub 2017 Oct 17.

Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd, Taipei, 100, Taiwan.

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http://dx.doi.org/10.1186/s12890-017-0478-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646116PMC
October 2017

Psychological distress and coping strategies among women with incurable lung cancer: a qualitative study.

Support Care Cancer 2018 Mar 10;26(3):989-996. Epub 2017 Oct 10.

Department of Internal Medicine, College of Medicine, National Taiwan University Hospital and National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s00520-017-3919-xDOI Listing
March 2018

Astrocyte-elevated gene-1 confers resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase expression.

Oncotarget 2017 Sep 28;8(37):61901-61916. Epub 2017 Jun 28.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.18717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617473PMC
September 2017

Severe exacerbation and pneumonia in COPD patients treated with fixed combinations of inhaled corticosteroid and long-acting beta2 agonist.

Int J Chron Obstruct Pulmon Dis 2017 21;12:2477-2485. Epub 2017 Aug 21.

Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.2147/COPD.S139035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571846PMC
May 2018

Outcomes of cancer therapy administered to treatment-naïve lung cancer patients in the intensive care unit.

J Cancer 2017 5;8(11):1995-2003. Epub 2017 Jul 5.

Department of Internal Medicine, National Taiwan University Hospital, No.7, Zhongshan South Road, Taipei 100, Taiwan (ROC).

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http://dx.doi.org/10.7150/jca.18178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559960PMC
July 2017

The identification of the TRPM8 channel on primary culture of human nasal epithelial cells and its response to cooling.

Medicine (Baltimore) 2017 Aug;96(31):e7640

aDepartment of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center bGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University cDepartment of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University dDepartment of Pediatrics, Tungs' Taichung Metro Harbor Hospital eDepartment of Otolaryngology-Head and Neck Surgery, Shuang Ho Hospital, Taipei, Taiwan, Republic of China.

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http://Insights.ovid.com/crossref?an=00005792-201708040-0001
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http://dx.doi.org/10.1097/MD.0000000000007640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626133PMC
August 2017

Lung adenocarcinoma patients of young age have lower mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors.

ERJ Open Res 2017 Jul 12;3(3). Epub 2017 Jul 12.

Dept of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taiwan.

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http://dx.doi.org/10.1183/23120541.00092-2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507146PMC
July 2017

Clinical characteristics of bacteraemia caused by Burkholderia cepacia complex species and antimicrobial susceptibility of the isolates in a medical centre in Taiwan.

Int J Antimicrob Agents 2018 Mar 10;51(3):357-364. Epub 2017 Jul 10.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2017.07.004DOI Listing
March 2018

High incidence of fluoroquinolone resistance and effect of efflux pump inhibitors on moxifloxacin resistance among Mycobacterium tuberculosis isolates causing urinary tract infection in Taiwan.

Int J Antimicrob Agents 2017 Sep 28;50(3):491-495. Epub 2017 Jun 28.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2017.04.010DOI Listing
September 2017

Gefitinib or erlotinib in previously treated non-small-cell lung cancer patients: a cohort study in Taiwan.

Cancer Med 2017 Jul 22;6(7):1563-1572. Epub 2017 Jun 22.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.1002/cam4.1121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504326PMC
July 2017

Coexistence of the BRAF Mutation and EGFR Exon 20 Insertion in a Patient with Lung Adenocarcinoma.

J Thorac Oncol 2017 07;12(7):e94-e95

Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jtho.2017.03.004DOI Listing
July 2017

Expression of Notch Gene and Its Impact on Survival of Patients with Resectable Non-small Cell Lung Cancer.

J Cancer 2017 11;8(7):1292-1300. Epub 2017 May 11.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.7150/jca.17741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5463445PMC
May 2017