Chirag J Patel

Chirag J Patel

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Chirag J Patel

Chirag J Patel

Publications by authors named "Chirag J Patel"

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Family History-Wide Association Study to Identify Clinical and Environmental Risk Factors for Common Chronic Diseases.

Am J Epidemiol 2019 Aug;188(8):1563-1568

Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/aje/kwz125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670049PMC
August 2019

The Landscape of Genetic Content in the Gut and Oral Human Microbiome.

Cell Host Microbe 2019 08;26(2):283-295.e8

Section on Pathophysiology and Molecular Pharmacology, Joslin Diabetes Center, Boston, MA, USA; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA, USA; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2019.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716383PMC
August 2019

Signals Among Signals: Prioritizing Nongenetic Associations in Massive Data Sets.

Am J Epidemiol 2019 May;188(5):846-850

Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/aje/kwz031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494664PMC
May 2019

Exposome-wide association study of semen quality: Systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes.

Environ Int 2019 04 22;125:505-514. Epub 2018 Dec 22.

Department of Biomedical Informatics, Harvard Medical School, Harvard University, 10 Shattuck Street, Boston, MA 02115, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01604120183191
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http://dx.doi.org/10.1016/j.envint.2018.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400484PMC
April 2019

Conducting a Reproducible Mendelian Randomization Analysis Using the R Analytic Statistical Environment.

Curr Protoc Hum Genet 2019 04 15;101(1):e82. Epub 2019 Jan 15.

Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cphg.82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424604PMC
April 2019

Repurposing large health insurance claims data to estimate genetic and environmental contributions in 560 phenotypes.

Nat Genet 2019 02 14;51(2):327-334. Epub 2019 Jan 14.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0313-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358510PMC
February 2019

Age-dependent co-dependency structure of biomarkers in the general population of the United States.

Aging (Albany NY) 2019 Feb;11(5):1404-1426

Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.18632/aging.101842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428110PMC
February 2019

Using Big Data to Determine Reference Values for Laboratory Tests-Reply.

JAMA 2018 10;320(14):1496

Meta-Research Innovation Center at Stanford, Stanford University, Stanford, California.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2018.10956DOI Listing
October 2018

Model-averaged confounder adjustment for estimating multivariate exposure effects with linear regression.

Biometrics 2018 09 22;74(3):1034-1044. Epub 2018 Mar 22.

Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1111/biom.12860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518418PMC
September 2018

Toward Capturing the Exposome: Exposure Biomarker Variability and Coexposure Patterns in the Shared Environment.

Environ Sci Technol 2018 08 20;52(15):8801-8810. Epub 2018 Jul 20.

Department of Biomedical Informatics, Harvard Medical School , Harvard University , 10 Shattuck Street , Boston , Massachusetts 02115 , United States.

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http://dx.doi.org/10.1021/acs.est.8b01467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085725PMC
August 2018

Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility.

PLoS One 2018 25;13(5):e0196676. Epub 2018 May 25.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196676PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969750PMC
July 2018

Bedside Lung Ultrasound in Emergency Protocol as a Diagnostic Tool in Patients of Acute Respiratory Distress Presenting to Emergency Department.

J Emerg Trauma Shock 2018 Apr-Jun;11(2):125-129

Department of Emergency Medicine, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.

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http://dx.doi.org/10.4103/JETS.JETS_21_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994850PMC
June 2018

In the Era of Precision Medicine and Big Data, Who Is Normal?

JAMA 2018 May;319(19):1981-1982

Stanford Prevention Research Center, Stanford University, Stanford, California.

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http://dx.doi.org/10.1001/jama.2018.2009DOI Listing
May 2018

Systematic identification of correlates of HIV infection: an X-wide association study.

AIDS 2018 04;32(7):933-943

Center for Health Policy and the Center for Primary Care and Outcomes Research, Stanford University, Stanford, California.

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http://dx.doi.org/10.1097/QAD.0000000000001767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869155PMC
April 2018

METHODS TO ENHANCE THE REPRODUCIBILITY OF PRECISION MEDICINE.

Pac Symp Biocomput 2016 ;21:180-182

Department of Biomedical Informatics, Harvard Medical School, Boston, MA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167531PMC
February 2018

Leveraging Population-Based Clinical Quantitative Phenotyping for Drug Repositioning.

CPT Pharmacometrics Syst Pharmacol 2018 02 24;7(2):124-129. Epub 2018 Jan 24.

Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/psp4.12258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824113PMC
February 2018

Integrated Analysis of Gene Expression Differences in Twins Discordant for Disease and Binary Phenotypes.

Sci Rep 2018 01 8;8(1):17. Epub 2018 Jan 8.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41598-017-18585-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758574PMC
January 2018

Covariate selection for association screening in multiphenotype genetic studies.

Nat Genet 2017 Dec 16;49(12):1789-1795. Epub 2017 Oct 16.

Department of Medicine, University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/ng.3975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797835PMC
December 2017

METHODS TO ENSURE THE REPRODUCIBILITY OF BIOMEDICAL RESEARCH.

Pac Symp Biocomput 2017 ;22:117-119

Massachusetts General Hospital, Boston, MA, USA2Broad Institute, Cambridge, MA, USA,

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http://dx.doi.org/10.1142/9789813207813_0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984201PMC
July 2017

MeSHDD: Literature-based drug-drug similarity for drug repositioning.

J Am Med Inform Assoc 2017 May;24(3):614-618

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/jamia/ocw142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391732PMC
May 2017

The Exposome Research Paradigm: an Opportunity to Understand the Environmental Basis for Human Health and Disease.

Curr Environ Health Rep 2017 03;4(1):89-98

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St., Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s40572-017-0126-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363405PMC
March 2017

A standard database for drug repositioning.

Sci Data 2017 03 14;4:170029. Epub 2017 Mar 14.

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/sdata.2017.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349249PMC
March 2017

Analytic Complexity and Challenges in Identifying Mixtures of Exposures Associated with Phenotypes in the Exposome Era.

Authors:
Chirag J Patel

Curr Epidemiol Rep 2017 18;4(1):22-30. Epub 2017 Jan 18.

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St, Boston, MA 02115 USA.

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http://dx.doi.org/10.1007/s40471-017-0100-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306298PMC
January 2017

REPRODUCIBLE AND SHAREABLE QUANTIFICATIONS OF PATHOGENICITY.

Pac Symp Biocomput 2016 ;21:231-42

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St., Boston, MA, 02115, USA,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720982PMC
October 2016

A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey.

Sci Data 2016 10 25;3:160096. Epub 2016 Oct 25.

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St., Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/sdata.2016.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079122PMC
October 2016

Systematic assessment of pharmaceutical prescriptions in association with cancer risk: a method to conduct a population-wide medication-wide longitudinal study.

Sci Rep 2016 08 10;6:31308. Epub 2016 Aug 10.

Center for Primary Health Care Research, Department of Clinical Sciences, Lund University, Clinical Research Centre (CRC), building 28, floor 11, Jan Waldenströms gata 35, Skåne University Hospital, SE-205 02 Malmö, Sweden.

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http://dx.doi.org/10.1038/srep31308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979093PMC
August 2016

Environment-Wide Association Study of Blood Pressure in the National Health and Nutrition Examination Survey (1999-2012).

Sci Rep 2016 07 26;6:30373. Epub 2016 Jul 26.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/srep30373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960597PMC
July 2016

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

Bioinformatics 2016 06;32(12):i101-i110

Department of Genetics and Genomic Sciences Icahn Institute for Genomics and Multiscale Biology Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA Department of Population Health Science and Policy, New York City, NY 10029, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btw282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908366PMC
June 2016

Comment: Addressing the Need for Portability in Big Data Model Building and Calibration.

J Am Stat Assoc 2016;111(513):127-129. Epub 2016 May 5.

Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115.

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http://dx.doi.org/10.1080/01621459.2016.1149406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111861PMC
May 2016

Development of exposome correlation globes to map out environment-wide associations.

Pac Symp Biocomput 2015 :231-42

Center for Biomedical Informatics, Harvard Medical School, 10 Shattuck Street Boston, MA. 02215, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299925PMC
April 2016

Field-wide meta-analyses of observational associations can map selective availability of risk factors and the impact of model specifications.

J Clin Epidemiol 2016 Mar 28;71:58-67. Epub 2015 Sep 28.

Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, 1265 Welch Rd, MSOB X306, Stanford, CA 94305, USA; Department of Health Research and Policy, Stanford University School of Medicine, 150 Governor's Lane, Stanford, CA 94305, USA; Department of Statistics, Stanford University School of Humanities and Sciences, 390 Serra Mall, Stanford, CA 94305, USA; Meta-Research Innovation Center at Stanford (METRICS), Stanford School of Medicine, 1070 Arastradero Road, Palo Alto, CA 94304, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08954356150042
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http://dx.doi.org/10.1016/j.jclinepi.2015.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108175PMC
March 2016

Analytical Complexity in Detection of Gene Variant-by-Environment Exposure Interactions in High-Throughput Genomic and Exposomic Research.

Authors:
Chirag J Patel

Curr Environ Health Rep 2016 Mar;3(1):64-72

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St., Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s40572-016-0080-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789192PMC
March 2016

ksRepo: a generalized platform for computational drug repositioning.

BMC Bioinformatics 2016 Feb 9;17:78. Epub 2016 Feb 9.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12859-016-0931-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746802PMC
February 2016

aRrayLasso: a network-based approach to microarray interconversion.

Bioinformatics 2015 Dec 17;31(23):3859-61. Epub 2015 Aug 17.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1093/bioinformatics/btv469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653393PMC
December 2015

Assessment of vibration of effects due to model specification can demonstrate the instability of observational associations.

J Clin Epidemiol 2015 Sep 6;68(9):1046-58. Epub 2015 Jun 6.

Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St., Room 314A, Boston, MA 02115, USA; Department of Medicine, Stanford Prevention Research Center, Stanford University School of Medicine, Medical School Office Building, Room X306, 1265 Welch Rd, Stanford, CA 94305, USA; Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, CA 94305, USA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA; Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jclinepi.2015.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4555355PMC
September 2015

Genetic variability in molecular responses to chemical exposure.

Exp Suppl 2012;101:437-57

Department of Medicine, Stanford University, 1265 Welch Road, X338, Stanford, CA, 94305, USA,

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http://dx.doi.org/10.1007/978-3-7643-8340-4_15DOI Listing
March 2015

Placing epidemiological results in the context of multiplicity and typical correlations of exposures.

J Epidemiol Community Health 2014 Nov 12;68(11):1096-100. Epub 2014 Jun 12.

Department of Medicine, Stanford Prevention Research Center, Stanford, California, USA Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, California, USA Meta-Research Innovation Center at Stanford (METRICS), Stanford, California, USA.

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http://dx.doi.org/10.1136/jech-2014-204195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545966PMC
November 2014

Investigation of maternal environmental exposures in association with self-reported preterm birth.

Reprod Toxicol 2014 Jun 27;45:1-7. Epub 2013 Dec 27.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA; Lucile Packard Children's Hospital, Palo Alto, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2013.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316205PMC
June 2014

Studying the elusive environment in large scale.

JAMA 2014 Jun;311(21):2173-4

Stanford Prevention Research Center, Department of Health Research and Policy, Department of Medicine, Stanford University School of Medicine, Stanford, California3Department of Statistics, Stanford University School of Humanities and Sciences, Stanford.

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http://dx.doi.org/10.1001/jama.2014.4129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110965PMC
June 2014

Whole genome sequencing in support of wellness and health maintenance.

Genome Med 2013 27;5(6):58. Epub 2013 Jun 27.

School of Biology, Georgia Institute of Technology, 310 Ferst Drive, Atlanta GA 30332, USA ; Center for Health Discovery and Well Being, and School of Medicine, Emory University Midtown Hospital, 550 Peachtree St, Atlanta GA 30308, USA.

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http://dx.doi.org/10.1186/gm462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967117PMC
May 2014

Disease risk factors identified through shared genetic architecture and electronic medical records.

Sci Transl Med 2014 Apr;6(234):234ra57

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 1265 Welch Road, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/scitranslmed.3007191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323098PMC
April 2014

Diabetic severity and risk of kidney stone disease.

Eur Urol 2014 Jan 17;65(1):242-7. Epub 2013 Mar 17.

Department of Urology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2013.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866968PMC
January 2014

Diabetes severity, metabolic syndrome, and the risk of erectile dysfunction.

J Sex Med 2013 Dec 9;10(12):3102-9. Epub 2013 Sep 9.

Department of Urology, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1111/jsm.12318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891923PMC
December 2013

Systematic identification of interaction effects between validated genome- and environment-wide associations on Type 2 Diabetes Mellitus.

AMIA Jt Summits Transl Sci Proc 2013 18;2013:135. Epub 2013 Mar 18.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA., 94305 USA ; Lucile Packard Children's Hospital, Palo Alto, CA., 94304 USA ; Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA. 94305, USA.

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December 2013

Systematic evaluation of environmental and behavioural factors associated with all-cause mortality in the United States national health and nutrition examination survey.

Int J Epidemiol 2013 Dec 16;42(6):1795-810. Epub 2013 Dec 16.

Stanford Prevention Research Center, Stanford University School of Medicine, CA, USA Division of General Medical Disciplines, Stanford University School of Medicine, CA, USA Department of Urology, Stanford University School of Medicine, CA, USA and Division of Nephrology, Department of Medicine, Stanford University School of Medicine, CA, USA.

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http://dx.doi.org/10.1093/ije/dyt208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887569PMC
December 2013

Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus.

Hum Genet 2013 May 20;132(5):495-508. Epub 2013 Jan 20.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 1265 Welch Road, Room X-163 MS-5415, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1007/s00439-012-1258-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625410PMC
May 2013

Analysis of the genetic basis of disease in the context of worldwide human relationships and migration.

PLoS Genet 2013 May 23;9(5):e1003447. Epub 2013 May 23.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662561PMC
May 2013

Bevacizumab inhibits proliferation of choroidal endothelial cells by regulation of the cell cycle.

Clin Ophthalmol 2013 13;7:321-7. Epub 2013 Feb 13.

University of Florida, Department of Ophthalmology, Jacksonville, FL, USA.

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http://dx.doi.org/10.2147/OPTH.S41556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575188PMC
February 2013

Spectral domain optical coherence tomography documented rapid resolution of pseudophakic cystoid macular edema with topical difluprednate.

Clin Ophthalmol 2012 24;6:155-8. Epub 2012 Jan 24.

Department of Ophthalmology, University of Florida Jacksonville, FL, USA.

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http://dx.doi.org/10.2147/OPTH.S28151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267537PMC
October 2012

T-cell leukemia.

Ophthalmology 2012 Aug;119(8):1713-1714.e1

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http://dx.doi.org/10.1016/j.ophtha.2012.03.042DOI Listing
August 2012

Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels.

Int J Epidemiol 2012 Jun 15;41(3):828-43. Epub 2012 Mar 15.

Department of Pediatrics, Division of Systems Medicine, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1093/ije/dys003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396318PMC
June 2012

Predicting environmental chemical factors associated with disease-related gene expression data.

BMC Med Genomics 2010 May 6;3:17. Epub 2010 May 6.

Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1186/1755-8794-3-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880288PMC
May 2010

An Environment-Wide Association Study (EWAS) on type 2 diabetes mellitus.

PLoS One 2010 May 20;5(5):e10746. Epub 2010 May 20.

Department of Pediatrics and Medicine, Stanford University School of Medicine, Stanford, California, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010746PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873978PMC
May 2010