Chiharu Mizuguchi

Chiharu Mizuguchi

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Chiharu Mizuguchi

Chiharu Mizuguchi

Publications by authors named "Chiharu Mizuguchi"

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18Publications

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Mechanisms of aggregation and fibril formation of the amyloidogenic N-terminal fragment of apolipoprotein A-I.

J Biol Chem 2019 Sep 24;294(36):13515-13524. Epub 2019 Jul 24.

Department of Biophysical Chemistry, Kyoto Pharmaceutical University, 5 Misasagi-Nakauchi-cho, Yamashina-ku, Kyoto 607-8414, Japan

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http://dx.doi.org/10.1074/jbc.RA119.008000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737231PMC
September 2019

Lipid Bilayer Interactions of Amyloidogenic N-Terminal Fragment of Apolipoprotein A-I Probed by Förster Resonance Energy Transfer and Molecular Dynamics Simulations.

J Fluoresc 2018 Sep 15;28(5):1037-1047. Epub 2018 Jul 15.

Department of Biophysical Chemistry, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto, 607-8414, Japan.

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http://dx.doi.org/10.1007/s10895-018-2267-7DOI Listing
September 2018

Heparin promotes fibril formation by the N-terminal fragment of amyloidogenic apolipoprotein A-I.

FEBS Lett 2016 Oct 4;590(20):3492-3500. Epub 2016 Oct 4.

Department of Biophysical Chemistry, Kyoto Pharmaceutical University, Japan.

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http://dx.doi.org/10.1002/1873-3468.12426DOI Listing
October 2016

Combined thioflavin T-Congo red fluorescence assay for amyloid fibril detection.

Methods Appl Fluoresc 2016 09 6;4(3):034010. Epub 2016 Sep 6.

Department of Nuclear and Medical Physics, V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv 61022, Ukraine. Department of Neuroscience and Biomedical Engineering, School of Science and Technology, Aalto University, FI-00076, Espoo, Finland. Author to whom any correspondence should be addressed. 19/2 Tankopiya Str., ap. 47, Kharkov 61091, Ukraine.

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http://dx.doi.org/10.1088/2050-6120/4/3/034010DOI Listing
September 2016

Interactions of Lipid Membranes with Fibrillar Protein Aggregates.

Adv Exp Med Biol 2015 ;855:135-55

Department of Nuclear and Medical Physics, V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkov, 61077, Ukraine,

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http://dx.doi.org/10.1007/978-3-319-17344-3_6DOI Listing
October 2015

FRET evidence for untwisting of amyloid fibrils on the surface of model membranes.

Soft Matter 2015 Aug;11(31):6223-34

Department of Nuclear and Medical Physics, V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkov, 61022, Ukraine.

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http://dx.doi.org/10.1039/c5sm00183hDOI Listing
August 2015

Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes.

J Biol Chem 2015 Aug 14;290(34):20947-59. Epub 2015 Jul 14.

From the Institute of Biomedical Sciences, Graduate School of Pharmaceutical Sciences, Tokushima University, 1-78-1 Shomachi, Tokushima 770-8505, Japan,

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http://dx.doi.org/10.1074/jbc.M115.664227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543654PMC
August 2015

Membrane effects of N-terminal fragment of apolipoprotein A-I: a fluorescent probe study.

J Fluoresc 2015 Mar 18;25(2):253-61. Epub 2015 Jan 18.

Department of Nuclear and Medical Physics, V.N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkov, 61077, Ukraine,

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http://dx.doi.org/10.1007/s10895-015-1501-9DOI Listing
March 2015

Interaction of thioflavin T with amyloid fibrils of apolipoprotein A-I N-terminal fragment: resonance energy transfer study.

J Struct Biol 2014 Jan 15;185(1):116-24. Epub 2013 Nov 15.

Institute of Health Biosciences, Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1016/j.jsb.2013.10.017DOI Listing
January 2014

The extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrils.

FEBS Lett 2014 Jan 5;588(3):389-94. Epub 2013 Dec 5.

Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2013.11.031DOI Listing
January 2014

Interactions of apolipoprotein A-I with high-density lipoprotein particles.

Biochemistry 2013 Mar 4;52(11):1963-72. Epub 2013 Mar 4.

Lipid Research Group, Gastroenterology, Hepatology and Nutrition Division, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104-4318, United States.

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http://dx.doi.org/10.1021/bi400032yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603221PMC
March 2013

Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation.

J Biol Chem 2013 Jan 11;288(4):2848-56. Epub 2012 Dec 11.

Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1074/jbc.M112.428052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554949PMC
January 2013

Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4.

Biochemistry 2012 Jul 3;51(28):5580-8. Epub 2012 Jul 3.

Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1021/bi300672sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447985PMC
July 2012