Chien-fu Hung

Chien-fu Hung

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Chien-fu Hung

Chien-fu Hung

Publications by authors named "Chien-fu Hung"

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100Publications

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Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines.

J Biomed Sci 2019 May 27;26(1):41. Epub 2019 May 27.

Department of Pathology, Johns Hopkins Medical Institutes, 1550 Orleans Street, Cancer Research Building II, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1186/s12929-019-0536-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6535840PMC
May 2019

Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice.

Front Cell Infect Microbiol 2018 8;8:31. Epub 2018 Feb 8.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fcimb.2018.00031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809501PMC
February 2019

Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination.

Virology 2018 12 5;525:205-215. Epub 2018 Oct 5.

Department of Pathology and Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2018.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415901PMC
December 2018

Ascites Volumes and the Ovarian Cancer Microenvironment.

Front Oncol 2018 17;8:595. Epub 2018 Dec 17.

Division of Cancer Imaging Research, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fonc.2018.00595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304435PMC
December 2018

Therapeutic DNA Vaccines for Human Papillomavirus and Associated Diseases.

Hum Gene Ther 2018 09 16;29(9):971-996. Epub 2018 Mar 16.

1 Department of Pathology, Johns Hopkins Medical Institutions , Baltimore, Maryland.

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http://dx.doi.org/10.1089/hum.2017.197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152857PMC
September 2018

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer.

ACS Omega 2018 Sep 27;3(9):11917-11929. Epub 2018 Sep 27.

Department of Oncology, Department of Pathology, and Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland 21231, United States.

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http://pubs.acs.org/doi/10.1021/acsomega.8b01479
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http://dx.doi.org/10.1021/acsomega.8b01479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166221PMC
September 2018

SIRveNIB: Selective Internal Radiation Therapy Versus Sorafenib in Asia-Pacific Patients With Hepatocellular Carcinoma.

J Clin Oncol 2018 Jul 2;36(19):1913-1921. Epub 2018 Mar 2.

Pierce K.H. Chow, Su Pin Choo, Choon-Hua Thng, and Khee Chee Soo, National Cancer Centre Singapore; Pierce K.H. Chow and Mihir Gandhi, Duke-NUS Medical School; Mihir Gandhi, Say-Beng Tan, Ganesh Lekurwale, and Wei Ming Liew, Singapore Clinical Research Institute; Say-Beng Tan, SingHealth; Peng Chung Cheow, Albert Su-Chong Low, Anthony S.W. Goh, Kiang Hiong Tay, Richard H.G. Lo, Brian K.P. Goh, and David C.E. Ng, Singapore General Hospital; Kieron Lim, National University Hospital; Kenneth S.W. Mak, Khoo Teck Puat Hospital, Singapore; Maung Win Khin, Yangon GI and Liver Centre, Yangon, Myanmar; Ariunaa Khasbazar, National Cancer Center of Mongolia, Ulaanbaatar, Mongolia; Janus Ong, The Medical City, Pasig, and University of the Philippines Manila, Manila; Ian H.Y. Cua, St Luke's Medical Center-Global City, Taguig; Rolley R. Lobo, Davao Doctors Hospital, Davao; Catherine S.C. Teh, Makati Medical Center, Makati City, Philippines; Chanisa Chotipanich, Chulabhorn Hospital, Bangkok, Thailand; Laurentius A. Lesmana, Cipto Mangunkusumo Hospital, and University of Indonesia, Jakarta; Tjakra W. Manuaba, Sanglah Hospital, Denpasar, Indonesia; Boon Koon Yoong, University of Malaya Medical Centre, Kuala Lumpur; Aloysius Raj, Penang Adventist Hospital, Penang; Chiong Soon Law, Sarawak General Hospital, Kuching, Malaysia; Yun Hwan Kim, Korea University Anam Hospital; Yun Won Jong, Severance Hospital; Ho-Seong Han, Seoul National University Bundang Hospital; Si-Hyun Bae, Seoul St Mary's Hospital; Hyun-Ki Yoon, Asan Medical Center, Seoul, Republic of Korea; Rheun-Chuan Lee, Taipei Veterans General Hospital; Po-Chin Liang, National Taiwan University Hospital, Taipei; Chien-Fu Hung, Chang Gung Memorial Hospital Linkou Branch, Taoyuan, Cheng-Yuan Peng, China Medical University Hospital, Taichung, Taiwan; Adam Bartlett, Auckland City Hospital, Auckland, New Zealand; Kenneth Y.Y. Kok, The Brunei Cancer Centre, Jerudong, Brunei Darussalam; and Val Gebski, University of Sydney, National Health and Medical Research Council Clinical Trials Centre, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.2017.76.0892DOI Listing
July 2018

Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy.

Hum Gene Ther 2018 05 2;29(5):614-625. Epub 2018 Apr 2.

2 Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine , Baltimore, Maryland.

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http://dx.doi.org/10.1089/hum.2017.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930796PMC
May 2018

Intramuscular vaccination targeting mucosal tumor draining lymph node enhances integrins-mediated CD8+ T cell infiltration to control mucosal tumor growth.

Oncoimmunology 2018 24;7(8):e1463946. Epub 2018 May 24.

Departments of Pathology, Department of Obstetrics and Gynecology, Department of Molecular Microbiology and Immunology, and Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, United States.

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http://dx.doi.org/10.1080/2162402X.2018.1463946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136882PMC
May 2018

Programmed self-assembly of peptide-major histocompatibility complex for antigen-specific immune modulation.

Proc Natl Acad Sci U S A 2018 04 9;115(17):E4032-E4040. Epub 2018 Apr 9.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287;

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http://dx.doi.org/10.1073/pnas.1718434115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924900PMC
April 2018

Prophylactic immunization with human papillomavirus vaccines induces oral immunity in mice.

Laryngoscope 2018 01 4;128(1):E16-E20. Epub 2017 Sep 4.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, U.S.A.

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http://dx.doi.org/10.1002/lary.26772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739972PMC
January 2018

Immunologic responses to a novel DNA vaccine targeting human papillomavirus-11 E6E7.

Laryngoscope 2017 12 17;127(12):2713-2720. Epub 2017 Jul 17.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, U.S.A.

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http://dx.doi.org/10.1002/lary.26737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687988PMC
December 2017

Metabolomic characterization of experimental ovarian cancer ascitic fluid.

Metabolomics 2017 Oct 24;13. Epub 2017 Aug 24.

Division of Cancer Imaging Research, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1007/s11306-017-1254-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804489PMC
October 2017

Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model.

Vaccine 2017 07 7;35(31):3850-3858. Epub 2017 Jun 7.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, United States; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, United States; Department of Obstetrics and Gynecology, Johns Hopkins Medical Institutions, Baltimore, MD, United States; Department of Molecular Microbiology and Immunology, Johns Hopkins Medical Institutions, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.05.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524135PMC
July 2017

Predictive Factors for Additional ProGlide Deployment in Percutaneous Endovascular Aortic Repair.

J Vasc Interv Radiol 2017 Apr 9;28(4):570-575. Epub 2017 Feb 9.

Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Chang Gung Memorial Hospital, Linkou, and Chang Gung University, Taoyuan, Taiwan, ROC. Electronic address:

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http://dx.doi.org/10.1016/j.jvir.2016.12.1219DOI Listing
April 2017

The current state of therapeutic and T cell-based vaccines against human papillomaviruses.

Virus Res 2017 03 6;231:148-165. Epub 2016 Dec 6.

Department of Pathology, Johns Hopkins University, Baltimore, MD USA; Department of Oncology, Johns Hopkins University, Baltimore, MD USA. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2016.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325765PMC
March 2017

Stringent Response Factors PPX1 and PPK2 Play an Important Role in Mycobacterium tuberculosis Metabolism, Biofilm Formation, and Sensitivity to Isoniazid In Vivo.

Antimicrob Agents Chemother 2016 11 21;60(11):6460-6470. Epub 2016 Oct 21.

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore Maryland, USA

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http://dx.doi.org/10.1128/AAC.01139-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075050PMC
November 2016

Perspectives for therapeutic HPV vaccine development.

J Biomed Sci 2016 Nov 4;23(1):75. Epub 2016 Nov 4.

Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1186/s12929-016-0293-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096309PMC
November 2016

Immunotherapy for human papillomavirus-associated disease and cervical cancer: review of clinical and translational research.

J Gynecol Oncol 2016 Sep 31;27(5):e51. Epub 2016 May 31.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://dx.doi.org/10.3802/jgo.2016.27.e51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944018PMC
September 2016

Annexin A5 increases survival in murine sepsis model by inhibiting HMGB1-mediated pro-inflammation and coagulation.

Mol Med 2016 Sep 6;22:424-436. Epub 2016 Jul 6.

Department of Immunology, KU open innovation center and School of Medicine, Konkuk University, Chungju 380-701, South Korea.

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http://dx.doi.org/10.2119/molmed.2016.00026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072405PMC
September 2016

Performance of adaptive iterative dose reduction 3D integrated with automatic tube current modulation in radiation dose and image noise reduction compared with filtered-back projection for 80-kVp abdominal CT: Anthropomorphic phantom and patient study.

Eur J Radiol 2016 Sep 12;85(9):1666-72. Epub 2016 Jul 12.

Medical Physics Research Center, Institute for Radiological Research, Chang Gung University/Chang Gung Memorial Hospital, Linkou, 259 Wen-Hwa 1st Road, Kwei-Shan 333, Taoyuan, Taiwan; Department of Medical Imaging & Radiological Sciences, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan 333, Taoyuan, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2016.07.002DOI Listing
September 2016

Current state in the development of candidate therapeutic HPV vaccines.

Expert Rev Vaccines 2016 08 7;15(8):989-1007. Epub 2016 Mar 7.

a Department of Pathology , Johns Hopkins University , Baltimore , MD , USA.

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http://dx.doi.org/10.1586/14760584.2016.1157477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977850PMC
August 2016

Impact of spontaneous tumor rupture on prognosis of patients with T4 hepatocellular carcinoma.

J Surg Oncol 2016 Jun 7;113(7):789-95. Epub 2016 Apr 7.

Division of General Surgery, Department of Surgery, Chang Gung Memorial Hospital, Linkou, Chang Gung University, Taoyuan, Taiwan.

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http://dx.doi.org/10.1002/jso.24245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071691PMC
June 2016

GALNT14 genotype effectively predicts the therapeutic response in unresectable hepatocellular carcinoma treated with transcatheter arterial chemoembolization.

Pharmacogenomics 2016 Mar 12;17(4):353-66. Epub 2016 Feb 12.

Liver Research Center, Chang Gung Memorial Hospital, No. 5, Fu-Sing Street, Guishan Township, Taoyuan, Taiwan.

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http://dx.doi.org/10.2217/pgs.15.179DOI Listing
March 2016

Buccal injection of synthetic HPV long peptide vaccine induces local and systemic antigen-specific CD8+ T-cell immune responses and antitumor effects without adjuvant.

Cell Biosci 2016 3;6:17. Epub 2016 Mar 3.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD USA ; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD USA ; Departments of Pathology and Oncology, The Johns Hopkins University School of Medicine, CRB II Room 307, 1550 Orleans Street, Baltimore, MD 21231 USA.

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http://dx.doi.org/10.1186/s13578-016-0083-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778350PMC
March 2016

Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell-Mediated Tumor Control in the Genital Tract.

Clin Cancer Res 2016 Feb 29;22(3):657-69. Epub 2015 Sep 29.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Obstetrics and Gynecology, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Molecular Microbiology and Immunology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-15-0234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738102PMC
February 2016

Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease.

Cell Biosci 2016 25;6:16. Epub 2016 Feb 25.

Departments of Pathology, Department of Obstetrics and Gynecology, Department of Molecular Microbiology and Immunology, and Department of Oncology, Johns Hopkins Medical Institutions, CRBII Room 309, 1550 Orleans Street, Baltimore, MD 21231 USA.

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http://dx.doi.org/10.1186/s13578-016-0080-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766698PMC
February 2016

Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer.

PLoS One 2015 5;10(1):e116389. Epub 2015 Jan 5.

Department of Pathology, The Johns Hopkins University, Baltimore, Maryland, United States of America; Department of Oncology, The Johns Hopkins University, Baltimore, Maryland, United States of America; Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116389PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283968PMC
January 2016

Cancer immunotherapy employing an innovative strategy to enhance CD4+ T cell help in the tumor microenvironment.

PLoS One 2014 22;9(12):e115711. Epub 2014 Dec 22.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, United States of America; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115711PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274108PMC
December 2015

Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis: Impact of Early Response to 4 Weeks of Treatment.

Liver Cancer 2015 Dec 15;4(4):228-40. Epub 2015 Oct 15.

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Taoyuan, Taiwan (ROC).

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http://dx.doi.org/10.1159/000367737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698647PMC
December 2015

Treatment of tumors with vitamin E suppresses myeloid derived suppressor cells and enhances CD8+ T cell-mediated antitumor effects.

PLoS One 2014 29;9(7):e103562. Epub 2014 Jul 29.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103562PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114790PMC
November 2015

DNA vaccine for cancer immunotherapy.

Hum Vaccin Immunother 2014 ;10(11):3153-64

a Department of Pathology ; Johns Hopkins University ; Baltimore , MD USA.

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http://dx.doi.org/10.4161/21645515.2014.980686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514137PMC
October 2015

Immunologic Control of Mus musculus Papillomavirus Type 1.

PLoS Pathog 2015 Oct 23;11(10):e1005243. Epub 2015 Oct 23.

Department of Pathology, The Johns Hopkins University, Baltimore, Maryland, United States of America; Department of Oncology, The Johns Hopkins University, Baltimore, Maryland, United States of America; Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619818PMC
October 2015

Nanoparticle-induced intraperitoneal hyperthermia and targeted photoablation in treating ovarian cancer.

Oncotarget 2015 Sep;6(29):26861-75

Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei City, Taiwan.

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http://dx.doi.org/10.18632/oncotarget.4766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694958PMC
September 2015

Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination.

Cell Biosci 2015 25;5:35. Epub 2015 Jun 25.

Departments of Pathology, School of Medicine, Johns Hopkins University, CRBII Room 307, 1550 Orleans Street, Baltimore, MD 21231 USA ; Oncology, Johns Hopkins Medical Institutions, Baltimore, MD USA.

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http://dx.doi.org/10.1186/s13578-015-0025-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480891PMC
June 2015

Local administration of granulocyte macrophage colony-stimulating factor induces local accumulation of dendritic cells and antigen-specific CD8+ T cells and enhances dendritic cell cross-presentation.

Vaccine 2015 Mar 19;33(13):1549-55. Epub 2015 Feb 19.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, United States; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361388PMC
March 2015

Direct T cell activation via CD40 ligand generates high avidity CD8+ T cells capable of breaking immunological tolerance for the control of tumors.

PLoS One 2014 24;9(3):e93162. Epub 2014 Mar 24.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093162PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963987PMC
November 2014

Toll-like receptor agonist imiquimod facilitates antigen-specific CD8+ T-cell accumulation in the genital tract leading to tumor control through IFNγ.

Clin Cancer Res 2014 Nov 3;20(21):5456-67. Epub 2014 Jun 3.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland. Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216740PMC
November 2014

Cancer immunotherapy using a potent immunodominant CTL epitope.

Vaccine 2014 Oct 20;32(46):6039-48. Epub 2014 Sep 20.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, United States; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194155PMC
October 2014

Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth.

Adv Healthc Mater 2014 Jul 16;3(7):1044-52. Epub 2013 Dec 16.

Center for Nanomedicine, Johns Hopkins University School of Medicine, 400 N Broadway, Baltimore, MD, 21231, USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, 21205, USA.

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http://dx.doi.org/10.1002/adhm.201300519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059793PMC
July 2014

Control of HPV infection and related cancer through vaccination.

Recent Results Cancer Res 2014 ;193:149-71

Department of Pathology, The Johns Hopkins School of Medicine, Cancer Research Building II, Room 310, 1550 Orleans Street, Baltimore, MD, 21231, USA.

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http://dx.doi.org/10.1007/978-3-642-38965-8_9DOI Listing
April 2014

Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model.

Drug Deliv Transl Res 2014 Apr;4(2):203-9

Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205 (USA) ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218 (USA) ; Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, 400 N Broadway, Baltimore, MD 21287 (USA) ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287 (USA) ; Center for Cancer Nanotechnology Excellence, Institute for NanoBioTechnology, Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218 (USA) ; Center for Nanomedicine, Johns Hopkins University School of Medicine, 400 N Broadway, Baltimore, MD 21287 (USA).

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http://dx.doi.org/10.1007/s13346-013-0190-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956079PMC
April 2014

Intra-peritoneal hyperthermia combining α-galactosylceramide in the treatment of ovarian cancer.

PLoS One 2013 23;8(7):e69336. Epub 2013 Jul 23.

Graduate Institute of Mechanical and Electrical Engineering, National Taipei University of Technology, Taipei City, Taiwan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069336PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720534PMC
March 2014

A single nucleotide polymorphism on the GALNT14 gene as an effective predictor of response to chemotherapy in advanced hepatocellular carcinoma.

Int J Cancer 2014 Mar 3;134(5):1214-24. Epub 2013 Sep 3.

Liver Research Unit, Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan; Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.

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http://dx.doi.org/10.1002/ijc.28439DOI Listing
March 2014

Cervical Cancer: Development of Targeted Therapies Beyond Molecular Pathogenesis.

Curr Obstet Gynecol Rep 2014 Mar;3(1):18-32

Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA ; Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MD 21205, USA ; Department of Molecular Microbiology and Immunology, Johns Hopkins University, Baltimore, MD 21205, USA ; Department of Oncology, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1007/s13669-013-0068-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921905PMC
March 2014

Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors.

Clin Cancer Res 2014 Feb 3;20(3):644-57. Epub 2013 Dec 3.

Authors' Affiliations: Departments of Pathology, Obstetrics and Gynecology, Molecular Microbiology and Immunology, Oncology, and Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions; Department of Biostatistics and Bioinformatics, Sidney Kimmel Cancer Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland; Departments of Obstetrics and Gynecology, Kunming Medical University, Yunnan, China; Nephrology, Chang-Gung Memorial Hospital, Gueishan; Department of Obstetrics and Gynecology, Tri-Service General Hospital, Taipei, Taiwan; and Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946442PMC
February 2014

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.

Cancer Cell 2013 Dec;24(6):791-805

Department of Oncology, The Johns Hopkins University, Baltimore, MD 21231, USA; Department of Pathology, The Johns Hopkins University, Baltimore, MD 21231, USA; Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881268PMC
December 2013

Control of spontaneous ovarian tumors by CD8+ T cells through NKG2D-targeted delivery of antigenic peptide.

Cell Biosci 2013 Dec 20;3(1):48. Epub 2013 Dec 20.

Department of Pathology, School of Medicine, Johns Hopkins University, Bldg, CRBII Rm, 309, 1550 Orleans Street, Baltimore, Maryland 21231, USA.

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http://dx.doi.org/10.1186/2045-3701-3-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903078PMC
December 2013

Intratumoral injection of therapeutic HPV vaccinia vaccine following cisplatin enhances HPV-specific antitumor effects.

Cancer Immunol Immunother 2013 Jul 25;62(7):1175-85. Epub 2013 Apr 25.

Department of Pathology, Johns Hopkins Medical Institutions, CRB II Room 309, 1550 Orleans Street, Baltimore, MD 21231, USA.

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http://link.springer.com/content/pdf/10.1007/s00262-013-1421
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http://link.springer.com/10.1007/s00262-013-1421-y
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http://dx.doi.org/10.1007/s00262-013-1421-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690484PMC
July 2013

Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigen.

Cell Biosci 2013 Jul 15;3(1):29. Epub 2013 Jul 15.

Departments of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://dx.doi.org/10.1186/2045-3701-3-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750327PMC
July 2013

Innovative DNA vaccine to break immune tolerance against tumor self-antigen.

Hum Gene Ther 2013 Feb 30;24(2):181-8. Epub 2013 Jan 30.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1089/hum.2012.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581028PMC
February 2013

Ovarian cancer gene therapy using HPV-16 pseudovirion carrying the HSV-tk gene.

PLoS One 2012 17;7(7):e40983. Epub 2012 Jul 17.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040983PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398866PMC
January 2013

Side-by-side comparison of gene-based smallpox vaccine with MVA in nonhuman primates.

PLoS One 2012 31;7(7):e42353. Epub 2012 Jul 31.

Department of Molecular Virology, Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042353PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409187PMC
January 2013

Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine.

Cancer Immunol Immunother 2013 Jan 4;62(1):171-82. Epub 2012 Aug 4.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1007/s00262-012-1322-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543472PMC
January 2013

Dose-dense chemotherapy improves mechanisms of antitumor immune response.

Cancer Res 2013 Jan 29;73(1):119-27. Epub 2012 Oct 29.

Department of Obstetrics and Gynecology, Mackay Medical College, Sanzhi, New Taipei, Taiwan.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537885PMC
January 2013

Emerging human papillomavirus vaccines.

Expert Opin Emerg Drugs 2012 Dec 19;17(4):469-92. Epub 2012 Nov 19.

The Johns Hopkins Medical Institutions, Departments of Pathology, Baltimore, MD, USA.

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http://dx.doi.org/10.1517/14728214.2012.744393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786409PMC
December 2012

Depletion of ascorbic acid impairs NK cell activity against ovarian cancer in a mouse model.

Immunobiology 2012 Sep 2;217(9):873-81. Epub 2012 Jan 2.

Department of Anatomy, Chung-Ang University, College of Medicine, Seoul, Republic of Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S01712985110028
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http://dx.doi.org/10.1016/j.imbio.2011.12.010DOI Listing
September 2012

Immune mechanism of the antitumor effects generated by bortezomib.

J Immunol 2012 Sep 15;189(6):3209-20. Epub 2012 Aug 15.

Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei City, Taiwan.

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http://dx.doi.org/10.4049/jimmunol.1103826DOI Listing
September 2012

Radiation dose exposure of patients undergoing 320-row cardiac CT for assessing coronary angiography and global left ventricular function.

Int J Cardiovasc Imaging 2012 Jun 18;28 Suppl 1:1-5. Epub 2012 May 18.

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, College of Medicine, Chang Gung University, 5 Fuhsing Road, Kweishan Hsiang, 333 Taoyuan, Taiwan.

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http://dx.doi.org/10.1007/s10554-012-0065-xDOI Listing
June 2012

Safety and efficacy of image-guided percutaneous biopsies in the diagnosis of gastrointestinal stromal tumors.

Clin Imaging 2012 Jan-Feb;36(1):19-23

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, and School of Medicine, Chang Gung University, No. 5 Fusing Street, Taoyuan, Taiwan.

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http://dx.doi.org/10.1016/j.clinimag.2011.04.002DOI Listing
May 2012

Poorly expandable common bile duct with stones on endoscopic retrograde cholangiography.

World J Gastroenterol 2012 May;18(19):2396-401

Division of Therapeutic Endoscopy, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan, China.

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http://dx.doi.org/10.3748/wjg.v18.i19.2396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353375PMC
May 2012

Development of a DNA vaccine targeting Merkel cell polyomavirus.

Vaccine 2012 Feb 29;30(7):1322-9. Epub 2011 Dec 29.

Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.vaccine.2011.12.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784303PMC
February 2012

LAH4 enhances CD8+ T cell immunity of protein/peptide-based vaccines.

Vaccine 2012 Jan 24;30(4):784-93. Epub 2011 Nov 24.

Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.vaccine.2011.11.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253925PMC
January 2012

Cancer cells containing nanoscale chemotherapeutic drugs generate antiovarian cancer-specific CD4+ T cells in peritoneal space.

J Immunother 2012 Jan;35(1):1-13

Department of Anatomy, Research Institute for Translational System Biomics, Chung-Ang University, College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1097/CJI.0b013e3182328569DOI Listing
January 2012

Intraperitoneal administration of poly(I:C) with polyethylenimine leads to significant antitumor immunity against murine ovarian tumors.

Cancer Immunol Immunother 2011 Aug 28;60(8):1085-96. Epub 2011 Apr 28.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1007/s00262-011-1013-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631404PMC
August 2011

Direct peroral cholangioscopy and pancreatoscopy for diagnosis of a pancreatobiliary fistula caused by an intraductal papillary mucinous neoplasm of the pancreas: a case report.

Dig Endosc 2011 Jul;23(3):247-50

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, School of Medicine, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan.

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http://dx.doi.org/10.1111/j.1443-1661.2011.01126.xDOI Listing
July 2011

Vascular disrupting agent DMXAA enhances the antitumor effects generated by therapeutic HPV DNA vaccines.

J Biomed Sci 2011 Mar 8;18:21. Epub 2011 Mar 8.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://dx.doi.org/10.1186/1423-0127-18-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062584PMC
March 2011

Enhancement of protein vaccine potency by in vivo electroporation mediated intramuscular injection.

Vaccine 2011 Jan 4;29(5):1082-9. Epub 2010 Dec 4.

Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21231, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0264410X1001707
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http://dx.doi.org/10.1016/j.vaccine.2010.11.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026065PMC
January 2011