Chiara Pastrello

Chiara Pastrello

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Chiara Pastrello

Chiara Pastrello

Publications by authors named "Chiara Pastrello"

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Modeling tumor progression via the comparison of stage-specific graphs.

Methods 2018 01 3;132:34-41. Epub 2017 Jul 3.

Princess Margaret Cancer Centre, UHN, 101 College Street, M5G 1L7, Toronto, Canada; TECHNA Institute for the Advancement of Technology for Health, UHN, 101 College Street, M5G 1L7, Toronto, Canada; Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Canada; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2017.06.033DOI Listing
January 2018

pathDIP: an annotated resource for known and predicted human gene-pathway associations and pathway enrichment analysis.

Nucleic Acids Res 2017 01 28;45(D1):D419-D426. Epub 2016 Nov 28.

Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada

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http://dx.doi.org/10.1093/nar/gkw1082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5210562PMC
January 2017

Circulating plant miRNAs can regulate human gene expression in vitro.

Sci Rep 2016 09 8;6:32773. Epub 2016 Sep 8.

IBM Life Sciences Discovery Centre, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/srep32773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015063PMC
September 2016

Robust quantitative scratch assay.

Bioinformatics 2016 05 31;32(9):1439-40. Epub 2015 Dec 31.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, Princess Margaret Cancer Centre and Techna, University Health Network, Toronto, ON, Canada, Department of Computer Science, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/bioinformatics/btv746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848397PMC
May 2016

Integrated interactions database: tissue-specific view of the human and model organism interactomes.

Nucleic Acids Res 2016 Jan 29;44(D1):D536-41. Epub 2015 Oct 29.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 1L7, Canada Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, ON, M5S 1A4, Canada

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http://dx.doi.org/10.1093/nar/gkv1115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702811PMC
January 2016

Prioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic data.

PLoS Comput Biol 2015 Mar 18;11(3):e1004068. Epub 2015 Mar 18.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Department of Computer Science, University of Toronto, Toronto, Ontario, Canada; Techna Institute, University Health Network, Toronto, Ontario, Canada.

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https://dx.plos.org/10.1371/journal.pcbi.1004068
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http://dx.doi.org/10.1371/journal.pcbi.1004068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364883PMC
March 2015

In silico prediction of physical protein interactions and characterization of interactome orphans.

Nat Methods 2015 Jan 17;12(1):79-84. Epub 2014 Nov 17.

1] Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [3] Department of Computer Science, University of Toronto, Toronto, Ontario, Canada. [4] TECHNA Institute for the Advancement of Technology for Health, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nmeth.3178DOI Listing
January 2015

Integration, visualization and analysis of human interactome.

Biochem Biophys Res Commun 2014 Mar 1;445(4):757-73. Epub 2014 Feb 1.

Princess Margaret Cancer Centre, University Health Network and TECHNA Institute for the Advancement of Technology for Health, TMDT, Room 11-314, 101 College Street, Toronto, ON M5G 1L7, Canada; University of Toronto, Department of Medical Biophysics, Toronto, ON, Canada; University of Toronto, Department of Computer Science, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.01.151DOI Listing
March 2014

Integrated analysis of unclassified variants in mismatch repair genes.

Genet Med 2011 Feb;13(2):115-24

Experimental Oncology 1, Centro di Riferimento Oncologico, IRCCS, via Franco Gallini 2, Aviano, Pordenone, Italy.

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http://dx.doi.org/10.1097/GIM.0b013e3182011489DOI Listing
February 2011

Association between hsa-mir-146a genotype and tumor age-of-onset in BRCA1/BRCA2-negative familial breast and ovarian cancer patients.

Carcinogenesis 2010 Dec 1;31(12):2124-6. Epub 2010 Sep 1.

Unit of Experimental Oncology 1, Department of Molecular Oncology and Translational Research, Centro di Riferimento Oncologico, CRO Aviano National Cancer Institute, 33081 Aviano, Italy.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgq184DOI Listing
December 2010

Somatic mosaicism in a patient with Lynch syndrome.

Am J Med Genet A 2009 Feb;149A(2):212-5

Oncologia Sperimentale 1, Centro di Riferimento Oncologico, IRCCS, Aviano (PN), Italy.

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http://dx.doi.org/10.1002/ajmg.a.32620DOI Listing
February 2009

Stability of BAT26 in tumours of hereditary nonpolyposis colorectal cancer patients with MSH2 intragenic deletion.

Eur J Hum Genet 2006 Jan;14(1):63-8

Experimental Oncology 1, Department of Preclinical Research and Epidemiology, Centro Riferimento Oncologico-IRCCS, Aviano, Italy.

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http://dx.doi.org/10.1038/sj.ejhg.5201517DOI Listing
January 2006

MUC gene abnormalities in sporadic and hereditary mucinous colon cancers with microsatellite instability.

Dis Markers 2005 ;21(3):121-6

Department of Preclinical Research and Epidemiology, Centro Riferimento Oncologico, IRCCS, Aviano (PN), Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851629PMC
http://dx.doi.org/10.1155/2005/370908DOI Listing
January 2006