Chiara Borsari

Chiara Borsari

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Chiara Borsari

Chiara Borsari

Publications by authors named "Chiara Borsari"

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17Publications

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Structural Insights into the Development of Cycloguanil Derivatives as Pteridine-Reductase-1 Inhibitors.

ACS Infect Dis 2019 Jul 1;5(7):1105-1114. Epub 2019 May 1.

Department of Biotechnology, Chemistry and Pharmacy-Department of Excellence 2018-2020 , University of Siena , via Aldo Moro 2 , 53100 Siena , Italy.

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http://dx.doi.org/10.1021/acsinfecdis.8b00358DOI Listing
July 2019

Excited-state intramolecular proton transfer in a bioactive flavonoid provides fluorescence observables for recognizing its engagement with target proteins.

Photochem Photobiol Sci 2019 Mar 22. Epub 2019 Mar 22.

Department of Life Sciences, University of Modena and Reggio Emilia (UNIMORE), Via Campi 103, 41125 Modena, Italy.

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http://dx.doi.org/10.1039/c9pp00026gDOI Listing
March 2019

Target-based approaches for the discovery of new antimycobacterial drugs.

Drug Discov Today 2017 03 23;22(3):576-584. Epub 2016 Nov 23.

Department of Life Sciences, University of Modena and Reggio Emilia, Via G. Campi 103, 41125 Modena, Italy; Tydock Pharma srl, Strada Gherbella 294/B, Modena 41126, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2016.11.014DOI Listing
March 2017

X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors.

Eur J Med Chem 2016 Nov 29;123:649-664. Epub 2016 Jul 29.

Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via Aldo Moro 2, 53100 Siena, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234163063
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http://dx.doi.org/10.1016/j.ejmech.2016.07.066DOI Listing
November 2016

Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase.

J Med Chem 2016 10 29;59(19):9269-9275. Epub 2016 Sep 29.

Department of Life Sciences, University of Modena and Reggio Emilia , Via Campi, 103, 41125 Modena, Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.6b00977DOI Listing
October 2016

Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case.

ChemMedChem 2016 08 12;11(15):1653-66. Epub 2016 Jul 12.

Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.

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http://dx.doi.org/10.1002/cmdc.201600121DOI Listing
August 2016