Chia-Ron Yang

Chia-Ron Yang

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Chia-Ron Yang

Chia-Ron Yang

Publications by authors named "Chia-Ron Yang"

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29Publications

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4-Substituted 2-amino-3,4-dihydroquinazolines with a 3-hairpin turn side chain as novel inhibitors of BACE-1.

Bioorg Chem 2020 Jan 22;95:103135. Epub 2019 Jul 22.

School of Pharmacy, College of Medicine and Center for Innovative Therapeutics Discovery, National Taiwan University, No. 33, Lin Sen South Road, Taipei 10050, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bioorg.2019.103135DOI Listing
January 2020

Moscatilin Ameliorates Tau Phosphorylation and Cognitive Deficits in Alzheimer's Disease Models.

J Nat Prod 2019 07 10;82(7):1979-1988. Epub 2019 Jul 10.

School of Pharmacy, College of Medicine , National Taiwan University , Taipei 10050 , Taiwan.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00375DOI Listing
July 2019

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo.

Biochim Biophys Acta Mol Cell Res 2019 06 10;1866(6):992-1003. Epub 2019 Mar 10.

School of Pharmacy, College of Medicine, National Taiwan University, No. 33, Linsen S. Road, Taipei 10050, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.03.003DOI Listing
June 2019

The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells.

Clin Epigenetics 2018 12 29;10(1):162. Epub 2018 Dec 29.

School of Pharmacy, College of Medicine, National Taiwan University, No.33, Linsen S. Road, Taipei, 10050, Taiwan.

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http://dx.doi.org/10.1186/s13148-018-0595-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310984PMC
December 2018

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes.

J Med Chem 2018 08 9;61(16):7087-7102. Epub 2018 Aug 9.

School of Pharmacy, College of Pharmacy , Taipei Medical University , 250 Wuxing Street , Taipei 11031 , Taiwan.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00151DOI Listing
August 2018

The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer's disease model.

Cell Death Dis 2018 05 29;9(6):655. Epub 2018 May 29.

School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1038/s41419-018-0688-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974403PMC
May 2018

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo.

J Med Chem 2018 02 26;61(3):905-917. Epub 2018 Jan 26.

School of Pharmacy, College of Pharmacy, Taipei Medical University , 250 Wuxing Street, Taipei 11031, Taiwan.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.7b01404
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http://dx.doi.org/10.1021/acs.jmedchem.7b01404DOI Listing
February 2018

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity.

Eur J Med Chem 2017 Jan 15;125:1268-1278. Epub 2016 Nov 15.

School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.11.033DOI Listing
January 2017

Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes.

J Mol Med (Berl) 2014 Nov 23;92(11):1147-58. Epub 2014 Jul 23.

Department of Orthopedic Surgery, College of Medicine, National Taiwan University, No. 1, Sec. 1, Jen-Ai Road, Taipei, Taiwan.

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http://dx.doi.org/10.1007/s00109-014-1192-8DOI Listing
November 2014

Indole-3-ethylsulfamoylphenylacrylamides: potent histone deacetylase inhibitors with anti-inflammatory activity.

Eur J Med Chem 2014 Oct 7;85:468-79. Epub 2014 Aug 7.

School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02235234140074
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http://dx.doi.org/10.1016/j.ejmech.2014.08.020DOI Listing
October 2014

1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors.

Chembiochem 2013 Jul 20;14(10):1248-54. Epub 2013 Jun 20.

School of Pharmacy, College of Pharmacy, Taipei Medical University, 250 Wuxing Street, Taipei 11031 (Taiwan).

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http://dx.doi.org/10.1002/cbic.201300201DOI Listing
July 2013

Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways.

J Nutr Biochem 2011 Aug 9;22(8):732-40. Epub 2010 Nov 9.

School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1016/j.jnutbio.2010.06.004DOI Listing
August 2011

Potent anti-inflammatory effects of denbinobin mediated by dual inhibition of expression of inducible no synthase and cyclooxygenase 2.

Shock 2011 Feb;35(2):191-7

School of Pharmacy, Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1097/SHK.0b013e3181f0e9a8DOI Listing
February 2011

Thiazolidinediones inhibit TNF-alpha-mediated osteoclast differentiation of RAW264.7 macrophages and mouse bone marrow cells through downregulation of NFATc1.

Shock 2010 Jun;33(6):662-7

School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.1097/SHK.0b013e3181cc0738DOI Listing
June 2010

Intracerebral transplantation of neural stem cells combined with trehalose ingestion alleviates pathology in a mouse model of Huntington's disease.

J Neurosci Res 2009 Jan;87(1):26-33

Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1002/jnr.21817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895944PMC
January 2009

Decoy receptor 3 expression in AsPC-1 human pancreatic adenocarcinoma cells via the phosphatidylinositol 3-kinase-, Akt-, and NF-kappa B-dependent pathway.

J Immunol 2008 Dec;181(12):8441-9

School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.4049/jimmunol.181.12.8441DOI Listing
December 2008

Inhibition of neuronal migration by JONES antibody is independent of 9-O-acetyl GD3 in GD3-synthase knockout mice.

J Neurosci Res 2007 May;85(7):1381-90

Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912, USA.

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http://dx.doi.org/10.1002/jnr.21264DOI Listing
May 2007

High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway.

Cell Signal 2006 Mar 20;18(3):391-9. Epub 2005 Jun 20.

Department of Internal Medicine, Tao-Yuan General Hospital, Department of Health, the Executive Yuan, 1492 Chung-Shan. Road, Tao Yuan, Taiwan.

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http://dx.doi.org/10.1016/j.cellsig.2005.05.009DOI Listing
March 2006

Decoy receptor 3 increases monocyte adhesion to endothelial cells via NF-kappa B-dependent up-regulation of intercellular adhesion molecule-1, VCAM-1, and IL-8 expression.

J Immunol 2005 Feb;174(3):1647-56

Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan.

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http://dx.doi.org/10.4049/jimmunol.174.3.1647DOI Listing
February 2005