Chi-un Choe

Chi-un Choe

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Chi-un Choe

Chi-un Choe

Publications by authors named "Chi-un Choe"

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Mapping stimulation-induced beneficial and adverse effects in the subthalamic area of essential tremor patients.

Parkinsonism Relat Disord 2019 Jul 3;64:150-155. Epub 2019 Apr 3.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.03.028DOI Listing
July 2019

Evidence by GC-MS that lysine is an arginase-catalyzed metabolite of homoarginine in vitro and in vivo in humans.

Anal Biochem 2019 Jul 24;577:59-66. Epub 2019 Apr 24.

Institute of Toxicology, Core Unit Proteomics, Hannover Medical School, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2019.04.019DOI Listing
July 2019

Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHADS-VASc score in three cross-sectional studies.

J Neurol Sci 2019 02 31;397:156-161. Epub 2018 Dec 31.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.12.037DOI Listing
February 2019

Thalamic short pulse stimulation diminishes adverse effects in essential tremor patients.

Neurology 2018 08 25;91(8):e704-e713. Epub 2018 Jul 25.

From the Departments of Neurology (C.-u.C., U.H., A.G., C.B., C.G., M.P.-N.), Neurosurgery (M.S., J.K., W.H.), and Neurophysiology and Pathophysiology (A.G., C.K.E.M.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006033DOI Listing
August 2018

Cognitive performance of 20 healthy humans supplemented with L-homoarginine for 4 weeks.

J Clin Neurosci 2018 Apr 1;50:237-241. Epub 2018 Feb 1.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2018.01.035DOI Listing
April 2018

Impaired cardiac contractile function in arginine:glycine amidinotransferase knockout mice devoid of creatine is rescued by homoarginine but not creatine.

Cardiovasc Res 2018 Mar;114(3):417-430

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, BHF Centre of Research Excellence at the University of Oxford and the Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1093/cvr/cvx242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982714PMC
March 2018

Oral supplementation with L-homoarginine in young volunteers.

Br J Clin Pharmacol 2016 12 20;82(6):1477-1485. Epub 2016 Sep 20.

Department of Clinical Pharmacology and Toxicology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1111/bcp.13068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099544PMC
December 2016

Transcriptomic and metabolic analyses reveal salvage pathways in creatine-deficient AGAT(-/-) mice.

Amino Acids 2016 08 3;48(8):2025-39. Epub 2016 Mar 3.

Experimental Neuropediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00726-016-2202-7DOI Listing
August 2016

Low Homoarginine Levels in the Prognosis of Patients With Acute Chest Pain.

J Am Heart Assoc 2016 Apr 13;5(4):e002565. Epub 2016 Apr 13.

German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Germany Department of General and Interventional Cardiology, University Heart Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1161/JAHA.115.002565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859271PMC
April 2016

Homoarginine supplementation improves blood glucose in diet-induced obese mice.

Amino Acids 2015 Sep 16;47(9):1921-9. Epub 2015 Jun 16.

Experimental Neurophysiology, University of Cologne, Cologne, Germany,

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http://dx.doi.org/10.1007/s00726-015-2022-1DOI Listing
September 2015

Measurement of homoarginine in human and mouse plasma by LC-MS/MS and ELISA: a comparison and a biological application.

Amino Acids 2015 Sep 10;47(9):2015-22. Epub 2015 Jul 10.

Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

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http://link.springer.com/10.1007/s00726-015-2037-7
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http://dx.doi.org/10.1007/s00726-015-2037-7DOI Listing
September 2015

L-homoarginine and cardiovascular disease.

Curr Opin Clin Nutr Metab Care 2015 Jan;18(1):83-8

aInstitute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf bDZHK (Deutsches Zentrum für Herz-Kreislauf-Forschung e.V.), partner site Hamburg/Kiel/Lübeck cDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1097/MCO.0000000000000123DOI Listing
January 2015

Homoarginine and cardiovascular outcome in the population-based Dallas Heart Study.

Arterioscler Thromb Vasc Biol 2014 Nov 4;34(11):2501-7. Epub 2014 Sep 4.

From the Departments of Clinical Pharmacology and Toxicology (D.A., R.H.B., E.S.) and Neurology, Experimental Neuropediatrics (C.U.C.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany; DZHK (Deutsches Zentrum für Herz-Kreislauf-Forschung e.V.), Partner Site Hamburg/Kiel/Lübeck, Germany (D.A., R.H.B., E.S.); and Division of Cardiology, Department of Internal Medicine (M.O.G., J.A.d.L., D.K.M.) and Department of Clinical Sciences (C.R.A., D.K.M.), University of Texas Southwestern Medical Center, Dallas.

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http://dx.doi.org/10.1161/ATVBAHA.114.304398DOI Listing
November 2014

Differential regulation of AMPK activation in leptin- and creatine-deficient mice.

FASEB J 2013 Oct 28;27(10):4147-56. Epub 2013 Jun 28.

1Experimental Neuropediatrics, Center for Molecular Neurobiology and Department of Pediatrics, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251 Hamburg, Germany.

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http://www.fasebj.org/content/27/10/4147.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.12-225136
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http://dx.doi.org/10.1096/fj.12-225136DOI Listing
October 2013

Homoarginine--an independent marker of mortality in heart failure.

Int J Cardiol 2013 Oct 24;168(5):4907-9. Epub 2013 Jul 24.

Department of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273130131
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http://dx.doi.org/10.1016/j.ijcard.2013.07.099DOI Listing
October 2013

Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies.

Circulation 2013 Sep 4;128(13):1451-61. Epub 2013 Sep 4.

Departments of Neurology (C.C., O.S., C.G., T.M.), Experimental Neuropediatrics (C.C., M.S., D.I.), Department of Clinical Pharmacology and Toxicology (D.A., R.H.B., N.L., R.A.B., E.S.), and German Center for Cardiovascular Research (D.A., P.S.W., R.H.B., S.B., T.Z., E.S.), Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany (F.O., C.M., S. Baldus, S. Blankenberg, T.Z.); Department of Clinical Chemistry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (T.S.); Department of Cardiology and Angiology (P.S.W.), Gutenberg Health Study (P.S.W.), and Department of Clinical Chemistry (K.L.), Johannes Gutenberg University, Mainz, Germany; Experimental Neurophysiology, University Hospital Cologne, Köln, Germany (D.I.); German Center for Neurodegenerative Diseases, Bonn, Germany (D.I.); Department of Clinical Pharmacy and Pharmacotherapy, Martin-Luther-University Halle Wittenberg, Halle Germany (R.A.B.); Division of Cardiovascular and Diabetes Research, Multidisciplinary Cardiovascular Research Centre, University of Leeds, Leeds, UK (A.M.C., P.J.G.); Department of Radiology, Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands (C.N., A.H.); and Laboratory of Neurochemistry and Behavior, Born-Bunge Foundation, University of Antwerp, Antwerp, Belgium (B.M., P.P. De D.).

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http://circ.ahajournals.org/content/early/2013/09/04/CIRCULA
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http://circ.ahajournals.org/content/128/13/1451.full.pdf
Web Search
http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.000580DOI Listing
September 2013

A clinical and neurobiological case of IgM NMDA receptor antibody associated encephalitis mimicking bipolar disorder.

Psychiatry Res 2013 Jul 13;208(2):194-6. Epub 2012 Dec 13.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20253 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.psychres.2012.09.035DOI Listing
July 2013

L-arginine:glycine amidinotransferase deficiency protects from metabolic syndrome.

Hum Mol Genet 2013 Jan 1;22(1):110-23. Epub 2012 Oct 1.

Experimental Neuropediatrics, Center for Molecular Neurobiology and Department of Pediatrics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1093/hmg/dds407DOI Listing
January 2013

Nitroxyl in the central nervous system.

Antioxid Redox Signal 2011 May 1;14(9):1699-711. Epub 2011 Mar 1.

Department of Neurology, University Hospital Hamburg-Eppendorf, Germany.

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http://dx.doi.org/10.1089/ars.2010.3852DOI Listing
May 2011

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.

Stroke 2009 May 5;40(5):1849-57. Epub 2009 Mar 5.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.108.534503DOI Listing
May 2009

Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.

Proc Natl Acad Sci U S A 2008 Oct 3;105(41):15920-5. Epub 2008 Oct 3.

Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1073/pnas.0805062105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2572927PMC
October 2008

The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork.

Sci STKE 2006 Nov 28;2006(363):re15. Epub 2006 Nov 28.

Department of Pharmacology, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/stke.3632006re15DOI Listing
November 2006

C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.

Hum Mol Genet 2006 Oct 21;15(19):2888-902. Epub 2006 Aug 21.

Institute for Neural Signal Transduction, ZMNH, Department of Pediatrics, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://academic.oup.com/hmg/article/15/19/2888/630544/Ctermi
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http://dx.doi.org/10.1093/hmg/ddl230DOI Listing
October 2006

Functional coupling of chromogranin with the inositol 1,4,5-trisphosphate receptor shapes calcium signaling.

J Biol Chem 2004 Aug 11;279(34):35551-6. Epub 2004 Jun 11.

Department of Pharmacology and Cellular & Molecular Physiology, Yale University, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1074/jbc.M311261200DOI Listing
August 2004

A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.

J Biol Chem 2003 Dec 23;278(50):49699-706. Epub 2003 Sep 23.

Department of Pharmacology and Cellular and Molecular Physiology, Yale University, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1074/jbc.M309307200DOI Listing
December 2003