Chi-Ming Che

Chi-Ming Che

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Chi-Ming Che

Publications by authors named "Chi-Ming Che"

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Solvent-Induced Cluster-to-Cluster Transformation of Homoleptic Gold(I) Thiolates between Catenane and Ring-in-Ring Structures.

Angew Chem Int Ed Engl 2019 Nov 20;58(45):16297-16306. Epub 2019 Sep 20.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://doi.wiley.com/10.1002/anie.201909980
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http://dx.doi.org/10.1002/anie.201909980DOI Listing
November 2019

Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target.

Metallomics 2019 Nov 21;11(11):1925-1936. Epub 2019 Oct 21.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1039/c9mt00185aDOI Listing
November 2019

Strongly Luminescent Tungsten Emitters with Emission Quantum Yields of up to 84 %: TADF and High-Efficiency Molecular Tungsten OLEDs.

Angew Chem Int Ed Engl 2019 Oct 5;58(42):14896-14900. Epub 2019 Sep 5.

State Key Laboratory of Synthetic Chemistry, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/anie.201906698DOI Listing
October 2019

Highly Enantioselective Synthesis Using Prolinol as a Chiral Auxiliary: Silver-Mediated Synthesis of Axially Chiral Vinylallenes and Subsequent (Hetero)-Diels-Alder Reactions.

Org Lett 2019 Oct 25;21(19):7717-7721. Epub 2019 Sep 25.

State Key Laboratory of Synthetic Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , People's Republic of China.

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http://dx.doi.org/10.1021/acs.orglett.9b02514DOI Listing
October 2019

Thermally Stable Donor-Acceptor Type (Alkynyl)Gold(III) TADF Emitters Achieved EQEs and Luminance of up to 23.4% and 70 300 cd m in Vacuum-Deposited OLEDs.

Adv Sci (Weinh) 2019 Sep 6;6(18):1802297. Epub 2019 Aug 6.

State Key Laboratory of Synthetic Chemistry Institute of Molecular Functional Materials Department of Chemistry The University of Hong Kong Pokfulam Road Hong Kong SAR China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.2018022
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http://dx.doi.org/10.1002/advs.201802297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755518PMC
September 2019

An Antitumor Bis(N-Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target.

Angew Chem Int Ed Engl 2019 Aug 28;58(32):10914-10918. Epub 2019 Jun 28.

State Key Laboratory of Synthetic Chemistry, Aglaia-KEIIT Laboratory for Drug Discovery and Development and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1002/anie.201904131DOI Listing
August 2019

Direct Z-Scheme Hetero-phase Junction of Black/Red Phosphorus for Photocatalytic Water Splitting.

Angew Chem Int Ed Engl 2019 Aug 18;58(34):11791-11795. Epub 2019 Jul 18.

Key Laboratory of Photochemical Conversion and Optoelectronic Materials & HKU-CAS Joint Laboratory on New Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.

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http://dx.doi.org/10.1002/anie.201906416DOI Listing
August 2019

Intramolecular Nitrene Insertion into Saturated C-H-Bond-Mediated C-N Bond Cleavage of a Coordinated NHC Ligand.

Chemistry 2019 Aug 26;25(46):10828-10833. Epub 2019 Jul 26.

Department of Chemistry, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, P. R. China.

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http://dx.doi.org/10.1002/chem.201903012DOI Listing
August 2019

SBP2 deficiency in adipose tissue macrophages drives insulin resistance in obesity.

Sci Adv 2019 Aug 14;5(8):eaav0198. Epub 2019 Aug 14.

School of Chinese Medicine, The University of Hong Kong, 1/F, 10 Sassoon Road, Pokfulam, Hong Kong S.A.R. 00000, P.R. China.

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http://dx.doi.org/10.1126/sciadv.aav0198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693917PMC
August 2019

Kinetically Controlled Self-Assembly of Phosphorescent Au Aggregates and Ligand-to-Metal-Metal Charge Transfer Excited State: A Combined Spectroscopic and DFT/TDDFT Study.

J Am Chem Soc 2019 Jul 15;141(29):11572-11582. Epub 2019 Jul 15.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China.

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http://dx.doi.org/10.1021/jacs.9b04007DOI Listing
July 2019

Ruthenium(II) Porphyrin Quinoid Carbene Complexes: Synthesis, Crystal Structure, and Reactivity toward Carbene Transfer and Hydrogen Atom Transfer Reactions.

J Am Chem Soc 2019 Jun 22;141(22):9027-9046. Epub 2019 May 22.

State Key Laboratory of Synthetic Chemistry and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong SAR , China.

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http://dx.doi.org/10.1021/jacs.9b03357DOI Listing
June 2019

Efficient acceptorless photo-dehydrogenation of alcohols and -heterocycles with binuclear platinum(ii) diphosphite complexes.

Chem Sci 2019 May 2;10(18):4883-4889. Epub 2019 Apr 2.

Department of Chemistry , Southern University of Science and Technology of China , Shenzhen , Guangdong 518055 , P. R. China.

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http://dx.doi.org/10.1039/c8sc05600eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510317PMC
May 2019

Stable iridium(iv) complexes supported by tetradentate salen ligands. Synthesis, structures and reactivity.

Chem Commun (Camb) 2019 Mar;55(25):3606-3609

State Key Laboratory of Synthetic Chemistry and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1039/c8cc10220aDOI Listing
March 2019

A Multifunctional Hydrogel Delivers Gold Compound and Inhibits Human Lung Cancer Xenograft.

Pharm Res 2019 Mar 8;36(4):61. Epub 2019 Mar 8.

Department of Chemistry and Chemical Biology Centre, The University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1007/s11095-019-2581-zDOI Listing
March 2019

Fast Synthesis of Iridium(III) Complexes Incorporating a Bis(diphenylphorothioyl)amide Ligand for Efficient Pure Green OLEDs.

ACS Appl Mater Interfaces 2019 Feb 7;11(7):7184-7191. Epub 2019 Feb 7.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong SAR , P. R. China.

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http://dx.doi.org/10.1021/acsami.8b19318DOI Listing
February 2019

An Effective [Fe(TFDMAP)Cl] Catalyst for C-H Bond Amination with Aryl and Alkyl Azides.

Org Lett 2019 02 4;21(4):895-899. Epub 2019 Feb 4.

State Key Laboratory of Synthetic Chemistry and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China.

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http://dx.doi.org/10.1021/acs.orglett.8b03765DOI Listing
February 2019

Perfluoroalkyl Aziridines with Ruthenium Porphyrin Carbene Intermediates.

Org Lett 2019 01 21;21(1):85-89. Epub 2018 Dec 21.

State Key Laboratory of Synthetic Chemistry and Department of Chemistry , The University of Hong Kong, Hong Kong and HKU Shenzhen Institute of Research & Innovation , Shenzhen 518053 , China.

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http://pubs.acs.org/doi/10.1021/acs.orglett.8b03514
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http://dx.doi.org/10.1021/acs.orglett.8b03514DOI Listing
January 2019

Luminescent ruffled iridium(iii) porphyrin complexes containing N-heterocyclic carbene ligands: structures, spectroscopies and potent antitumor activities under dark and light irradiation conditions.

Chem Sci 2019 Jan 10;10(1):293-309. Epub 2018 Oct 10.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , HKU-CAS Joint Laboratory on New Materials and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c8sc02920bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335621PMC
January 2019

Counteranion- and Solvent-Mediated Chirality Transfer in the Supramolecular Polymerization of Luminescent Platinum(II) Complexes.

Angew Chem Int Ed Engl 2018 Dec 27;57(52):17189-17193. Epub 2018 Nov 27.

HKU-CAS Joint Laboratory on New Materials, State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/anie.201811943DOI Listing
December 2018

Visible-Light-Promoted Transition-Metal-Free Phosphinylation of Heteroaryl Halides in the Presence of Potassium tert-Butoxide.

Org Lett 2018 12 12;20(24):7816-7820. Epub 2018 Dec 12.

State Key Laboratory of Synthetic Chemistry, and Department of Chemistry , The University of Hong Kong , Pokfulam Road, Hong Kong , China.

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http://dx.doi.org/10.1021/acs.orglett.8b03265DOI Listing
December 2018

Air-Stable Blue Phosphorescent Tetradentate Platinum(II) Complexes as Strong Photo-Reductant.

Angew Chem Int Ed Engl 2018 Oct 4;57(43):14129-14133. Epub 2018 Oct 4.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://doi.wiley.com/10.1002/anie.201808642
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http://dx.doi.org/10.1002/anie.201808642DOI Listing
October 2018

N-Heterocyclic Carbene Iron(III) Porphyrin-Catalyzed Intramolecular C(sp )-H Amination of Alkyl Azides.

Angew Chem Int Ed Engl 2018 09 16;57(37):11947-11951. Epub 2018 Aug 16.

State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1002/anie.201806059DOI Listing
September 2018

Near-Infrared Phosphorescent Supramolecular Alkyl/Aryl-Iridium Porphyrin Assemblies by Axial Coordination.

Chemistry 2018 Sep 16;24(54):14400-14408. Epub 2018 Sep 16.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.

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http://dx.doi.org/10.1002/chem.201803238DOI Listing
September 2018

Iron Porphyrin Catalyzed Insertion Reaction of N-Tosylhydrazone-Derived Carbenes into X-H (X = Si, Sn, Ge) Bonds.

Org Lett 2018 08 25;20(15):4641-4644. Epub 2018 Jul 25.

Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis , Shanghai Institute of Organic Chemistry , 354 Feng Lin Road , Shanghai 200032 , P. R. China.

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http://dx.doi.org/10.1021/acs.orglett.8b01931DOI Listing
August 2018

Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from Juncus effusus.

J Proteome Res 2018 07 21;17(7):2470-2479. Epub 2018 Jun 21.

Department of Chemistry, Chemical Biology Center and State Key Laboratory of Synthetic Chemistry , The University of Hong Kong , Hong Kong , China.

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http://dx.doi.org/10.1021/acs.jproteome.8b00227DOI Listing
July 2018

Arylruthenium(III) Porphyrin-Catalyzed C-H Oxidation and Epoxidation at Room Temperature and [Ru(Por)(O)(Ph)] Intermediate by Spectroscopic Analysis and Density Functional Theory Calculations.

J Am Chem Soc 2018 06 21;140(22):7032-7042. Epub 2018 May 21.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China.

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http://dx.doi.org/10.1021/jacs.8b04470DOI Listing
June 2018

Tunable Multicolor Phosphorescence of Crystalline Polymeric Complex Salts with Metallophilic Backbones.

Angew Chem Int Ed Engl 2018 05 25;57(21):6279-6283. Epub 2018 Apr 25.

Department of Chemistry, South University of Science and Technology of China, Shenzhen, Guangdong, 518055, P. R. China.

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http://dx.doi.org/10.1002/anie.201803965DOI Listing
May 2018

Anticancer metal-N-heterocyclic carbene complexes of gold, platinum and palladium.

Curr Opin Chem Biol 2018 04 11;43:30-36. Epub 2017 Nov 11.

Department of Chemistry, State Key Laboratory of Synthetic Chemistry and Chemical Biology Centre, The University of Hong Kong, Pokfulam, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.cbpa.2017.10.014DOI Listing
April 2018

Rh -Catalyzed Intermolecular C-H Arylation of Aromatics with Diazo Quinones.

Chemistry 2018 Apr 13;24(19):4815-4819. Epub 2018 Mar 13.

State Key Laboratory of Synthetic Chemistry and, Department of Chemistry, The University of Hong Kong, Hong Kong, P. R. China.

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http://dx.doi.org/10.1002/chem.201800648DOI Listing
April 2018

Synthesis of peri-Substituted (Naphthalen-1-yl)phosphine Ligands by Rhodium(I)-Catalyzed Phosphine-Directed C-H Arylation.

Org Lett 2018 04 21;20(7):1810-1814. Epub 2018 Mar 21.

State Key Laboratory of Synthetic Chemistry, and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China.

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http://dx.doi.org/10.1021/acs.orglett.8b00305DOI Listing
April 2018

A theoretical study on the oxidation of alkenes to aldehydes catalyzed by ruthenium porphyrins using O as the sole oxidant.

Dalton Trans 2018 Apr;47(15):5286-5297

Department of Chemistry, the University of Hong Kong, Hong Kong, P. R. China.

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http://dx.doi.org/10.1039/C8DT00614HDOI Listing
April 2018

The Metal-Metal-to-Ligand Charge Transfer Excited State and Supramolecular Polymerization of Luminescent Pincer Pd -Isocyanide Complexes.

Angew Chem Int Ed Engl 2018 03 2;57(12):3089-3093. Epub 2018 Feb 2.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/anie.201712249DOI Listing
March 2018

-Oxoruthenium complexes supported by chiral tetradentate amine (N) ligands for hydrocarbon oxidations.

Chem Sci 2018 Mar 15;9(10):2803-2816. Epub 2018 Feb 15.

State Key Laboratory of Synthetic Chemistry , Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c7sc05224cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943683PMC
March 2018

Interstitial P-Doped CdS with Long-Lived Photogenerated Electrons for Photocatalytic Water Splitting without Sacrificial Agents.

Adv Mater 2018 Feb 27;30(6). Epub 2017 Dec 27.

Key Laboratory of Photochemical Conversion and Optoelectronic Materials and HKU-CAS Joint Laboratory on New Materials, Technical Institute of Physics and Chemistry & University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, 100190, P. R. China.

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http://dx.doi.org/10.1002/adma.201705941DOI Listing
February 2018

Metal-organic framework composites with luminescent pincer platinum(ii) complexes: MMLCT emission and photoinduced dehydrogenation catalysis.

Chem Sci 2018 Feb 1;9(8):2357-2364. Epub 2018 Feb 1.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , HKU-CAS Joint Laboratory on New Materials , Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://xlink.rsc.org/?DOI=C7SC04528J
Publisher Site
http://dx.doi.org/10.1039/c7sc04528jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897847PMC
February 2018

cis-Dioxorhenium(V/VI) Complexes Supported by Neutral Tetradentate N Ligands. Synthesis, Characterization, and Spectroscopy.

Inorg Chem 2017 Dec 30;56(24):15066-15080. Epub 2017 Nov 30.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, and Department of Chemistry, The University of Hong Kong , Pokfulam Road, Hong Kong, People's Republic of Chinaa.

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http://dx.doi.org/10.1021/acs.inorgchem.7b02404DOI Listing
December 2017

Highly Luminescent Pincer Gold(III) Aryl Emitters: Thermally Activated Delayed Fluorescence and Solution-Processed OLEDs.

Angew Chem Int Ed Engl 2017 11 5;56(45):14036-14041. Epub 2017 Oct 5.

State Key Laboratory of Synthetic Chemistry, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://doi.wiley.com/10.1002/anie.201707193
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http://dx.doi.org/10.1002/anie.201707193DOI Listing
November 2017

Assembly of strongly phosphorescent hetero-bimetallic and -trimetallic [2]catenane structures based on a coinage metal alkynyl system.

Chem Sci 2017 Nov 4;8(11):7815-7820. Epub 2017 Oct 4.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email: ; Email:

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http://xlink.rsc.org/?DOI=C7SC03529B
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http://dx.doi.org/10.1039/c7sc03529bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694978PMC
November 2017

Strongly Luminescent Cyclometalated Gold(III) Complexes Supported by Bidentate Ligands Displaying Intermolecular Interactions and Tunable Emission Energy.

Chem Asian J 2017 Aug 27;12(16):2104-2120. Epub 2017 Jul 27.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/asia.201700686DOI Listing
August 2017

Platinum(ii) photo-catalysis for highly selective difluoroalkylation reactions.

Chem Commun (Camb) 2017 Aug;53(64):8948-8951

Department of Chemistry, South University of Science and Technology of China, Shenzhen, Guangdong 518055, P. R. China.

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http://dx.doi.org/10.1039/c7cc03823bDOI Listing
August 2017

Efficient Color-Tunable Copper(I) Complexes and Their Applications in Solution-Processed Organic Light-Emitting Diodes.

Chem Asian J 2017 Jul 10;12(13):1490-1498. Epub 2017 Mar 10.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/asia.201700081DOI Listing
July 2017

Luminescent Cyclometalated Gold(III) Alkyl Complexes: Photophysical and Photochemical Properties.

Inorg Chem 2017 May 13;56(9):5046-5059. Epub 2017 Apr 13.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong , Pokfulam Road, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1021/acs.inorgchem.7b00180DOI Listing
May 2017

Tripodal S-Ligand Complexes of Copper(I) as Catalysts for Alkene Aziridination, Sulfide Sulfimidation, and C-H Amination.

Inorg Chem 2017 Apr 30;56(8):4253-4257. Epub 2017 Mar 30.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong , Pokfulam Road, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1021/acs.inorgchem.7b00226DOI Listing
April 2017

Cyclometalated Gold(III) Complexes Containing N-Heterocyclic Carbene Ligands Engage Multiple Anti-Cancer Molecular Targets.

Angew Chem Int Ed Engl 2017 03 1;56(14):3892-3896. Epub 2017 Mar 1.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Chemical Biology Centre and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1002/anie.201612583DOI Listing
March 2017

A multi-functional PEGylated gold(iii) compound: potent anti-cancer properties and self-assembly into nanostructures for drug co-delivery.

Chem Sci 2017 Mar 22;8(3):1942-1953. Epub 2016 Nov 22.

State Key Laboratory of Synthetic Chemistry , Department of Chemistry and Chemical Biology Centre , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c6sc03210aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384453PMC
March 2017

The interplay between fluorescence and phosphorescence with luminescent gold(i) and gold(iii) complexes bearing heterocyclic arylacetylide ligands.

Chem Sci 2017 Mar 5;8(3):2352-2364. Epub 2016 Dec 5.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong SAR , China . Email: ; Email:

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http://dx.doi.org/10.1039/c6sc03775eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365001PMC
March 2017

Wheel-to-rhomboid isomerization as well as nitrene transfer catalysis of ruthenium-thiolate wheels.

Chem Commun (Camb) 2017 Feb;53(16):2419-2422

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. and HKU Shenzhen Institute of Research and Innovation, Shenzhen 518053, China.

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http://dx.doi.org/10.1039/c6cc09903cDOI Listing
February 2017

Palladium(II) Acetylide Complexes with Pincer-Type Ligands: Photophysical Properties, Intermolecular Interactions, and Photo-cytotoxicity.

Chem Asian J 2017 Jan 13;12(1):145-158. Epub 2016 Dec 13.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/asia.201601414DOI Listing
January 2017

Luminescent Tungsten(VI) Complexes: Photophysics and Applicability to Organic Light-Emitting Diodes and Photocatalysis.

Angew Chem Int Ed Engl 2017 01 5;56(1):133-137. Epub 2016 Dec 5.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/anie.201608240DOI Listing
January 2017

Highly efficient hydrolysis of ammonia borane by anion (OH, F, Cl)-tuned interactions between reactant molecules and CoP nanoparticles.

Chem Commun (Camb) 2017 Jan;53(4):705-708

Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.

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http://dx.doi.org/10.1039/c6cc08120gDOI Listing
January 2017

A macromolecular cyclometalated gold(iii) amphiphile displays long-lived emissive excited state in water: self-assembly and in vitro photo-toxicity.

Chem Commun (Camb) 2016 Nov;52(90):13273-13276

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China. and HKU-Shenzhen Institute of Research and Innovation, Shenzhen 518053, China.

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http://xlink.rsc.org/?DOI=C6CC06767K
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http://dx.doi.org/10.1039/c6cc06767kDOI Listing
November 2016

A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down-Regulation of Vascular Endothelial Growth Factor Receptor-2 and Suppresses Tumor Growth In Vivo.

Angew Chem Int Ed Engl 2016 10 26;55(43):13524-13528. Epub 2016 Sep 26.

State Key Laboratory of Synthetic Chemistry, Chemical Biology Centre and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P.R. China.

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http://dx.doi.org/10.1002/anie.201608094DOI Listing
October 2016

Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression.

Angew Chem Int Ed Engl 2016 09 29;55(39):11935-9. Epub 2016 Aug 29.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1002/anie.201602814DOI Listing
September 2016

Highly luminescent palladium(ii) complexes with sub-millisecond blue to green phosphorescent excited states. Photocatalysis and highly efficient PSF-OLEDs.

Chem Sci 2016 Sep 15;7(9):6083-6098. Epub 2016 Jun 15.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , HKU-CAS Joint Laboratory on New Materials and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c6sc00462hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024183PMC
September 2016

Highly Enantioselective Iron-Catalyzed cis-Dihydroxylation of Alkenes with Hydrogen Peroxide Oxidant via an Fe(III) -OOH Reactive Intermediate.

Angew Chem Int Ed Engl 2016 08 26;55(35):10253-7. Epub 2016 Jul 26.

Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, 354 Feng Lin Road, Shanghai, China.

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August 2016

From Cluster to Polymer: Ligand Cone Angle Controlled Syntheses and Structures of Copper(I) Alkynyl Complexes.

Angew Chem Int Ed Engl 2016 08 28;55(35):10312-6. Epub 2016 Jul 28.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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August 2016

Alkynyl gold(I) phosphane complexes: Evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex.

J Inorg Biochem 2016 07 30;160:140-8. Epub 2015 Dec 30.

Institute of Medicinal and Pharmaceutical Chemistry, Technische Universität Braunschweig, Beethovenstrasse 55, 38106 Braunschweig, Germany; PVZ - Center of Pharmaceutical Engineering, Franz-Liszt-Straße 35A, 38106 Braunschweig, Germany. Electronic address:

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July 2016

IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma.

Oncotarget 2016 Jul;7(28):43792-43804

School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong S.A.R, P.R. of China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5190060PMC
July 2016

M8L12 cubic cages with all facial Δ or facial Λ configuration: effects of surface anions on the occupancy of the cage and anion exchange.

Chem Commun (Camb) 2016 May 11;52(35):5981-4. Epub 2016 Apr 11.

Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China.

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May 2016

Four-Electron Oxidation of Phenols to p-Benzoquinone Imines by a (Salen)ruthenium(VI) Nitrido Complex.

J Am Chem Soc 2016 05 29;138(18):5817-20. Epub 2016 Apr 29.

Department of Biology and Chemistry and Institute of Molecular Functional Materials, City University of Hong Kong , Tat Chee Avenue, Hong Kong, China.

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http://dx.doi.org/10.1021/jacs.6b02923DOI Listing
May 2016

Stable luminescent iridium(iii) complexes with bis(N-heterocyclic carbene) ligands: photo-stability, excited state properties, visible-light-driven radical cyclization and CO reduction, and cellular imaging.

Chem Sci 2016 May 20;7(5):3123-3136. Epub 2016 Jan 20.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , HKU-CAS Joint Laboratory on New Materials and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c5sc04458hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003676PMC
May 2016

Identification of "sarsasapogenin-aglyconed" timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processing.

Chem Sci 2016 May 22;7(5):3206-3214. Epub 2016 Jan 22.

Department of Chemistry , The University of Hong Kong , Chemical Biology Centre , 8/F., The Hong Kong Jockey Club Building for Interdisciplinary Research, 5, Sassoon Road, Pokfulam , Hong Kong , China . Email: ; ; Tel: +852-28592154.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005341PMC
May 2016

Homoleptic gold(i) N-heterocyclic allenylidene complexes: excited-state properties and lyotropic chromonics.

Chem Commun (Camb) 2016 Apr;52(28):4983-6

State Key Laboratory of Synthetic Chemistry, HKU-CAS Joint Laboratory on New Materials, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, P. R. China.

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http://dx.doi.org/10.1039/c5cc09571aDOI Listing
April 2016

Highly phosphorescent platinum(ii) emitters: photophysics, materials and biological applications.

Chem Sci 2016 Mar 7;7(3):1653-1673. Epub 2016 Jan 7.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , HKU-CAS Joint Laboratory on New Materials and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090519PMC
March 2016

Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA.

Nat Commun 2016 Feb 17;7:10655. Epub 2016 Feb 17.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Chemical Biology Centre, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1038/ncomms10655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757794PMC
February 2016

Anticancer Gold(III) Porphyrins Target Mitochondrial Chaperone Hsp60.

Angew Chem Int Ed Engl 2016 Jan 9;55(4):1387-91. Epub 2015 Dec 9.

State Key Laboratory of Synthetic Chemistry, Chemical Biology Center, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong.

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http://dx.doi.org/10.1002/anie.201509612DOI Listing
January 2016

Cobalt(II) Porphyrin-Catalyzed Intramolecular Cyclopropanation of N-Alkyl Indoles/Pyrroles with Alkylcarbene: Efficient Synthesis of Polycyclic N-Heterocycles.

Angew Chem Int Ed Engl 2016 Jan 21;55(5):1810-5. Epub 2015 Dec 21.

HKU Shenzhen Institute of Research & Innovation, Shenzhen, China.

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http://dx.doi.org/10.1002/anie.201506418DOI Listing
January 2016

Chemical biology of anticancer gold(III) and gold(I) complexes.

Chem Soc Rev 2015 Dec 14;44(24):8786-801. Epub 2015 Apr 14.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Chemical Biology Centre and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1039/c5cs00132cDOI Listing
December 2015

Metal-organic framework composites with luminescent gold(iii) complexes. Strongly emissive and long-lived excited states in open air and photo-catalysis.

Chem Sci 2015 Dec 21;6(12):7105-7111. Epub 2015 Sep 21.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , HKU-CAS Joint Laboratory on New Materials , Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c5sc02216aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947532PMC
December 2015

Water oxidation catalysed by iron complex of ,'-dimethyl-2,11-diaza[3,3](2,6)pyridinophane. Spectroscopy of iron-oxo intermediates and density functional theory calculations.

Chem Sci 2015 Oct 22;6(10):5891-5903. Epub 2015 Jul 22.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email: ; Email:

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http://dx.doi.org/10.1039/c5sc01680kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950833PMC
October 2015

Deciphering Photoluminescence Dynamics and Reactivity of the Luminescent Metal-Metal-Bonded Excited State of a Binuclear Gold(I) Phosphine Complex Containing Open Coordination Sites.

Chemistry 2015 Sep;21(40):13888-93

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P. R. China).

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http://dx.doi.org/10.1002/chem.201503045DOI Listing
September 2015

Dysregulation of clathrin promotes thyroid cell growth and contributes to multinodular goiter pathogenesis.

Biochim Biophys Acta 2015 Aug 13;1852(8):1676-86. Epub 2015 May 13.

Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2015.05.005DOI Listing
August 2015

Luminescent zinc(ii) and copper(i) complexes for high-performance solution-processed monochromic and white organic light-emitting devices.

Chem Sci 2015 Aug 2;6(8):4623-4635. Epub 2015 Jun 2.

State Key Laboratory of Synthetic Chemistry , HKU-CAS Joint Laboratory on New Materials, and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong SAR , China . Email:

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http://dx.doi.org/10.1039/c4sc03161jDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667404PMC
August 2015

Luminescent platinum(ii) complexes with self-assembly and anti-cancer properties: hydrogel, pH dependent emission color and sustained-release properties under physiological conditions.

Chem Sci 2015 Jul 28;6(7):3823-3830. Epub 2015 Apr 28.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , Chemical Biology Centre and Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong , China . Email:

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http://dx.doi.org/10.1039/c4sc03635bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707448PMC
July 2015

Gold and silver catalysis: from organic transformation to bioconjugation.

Org Biomol Chem 2015 Jun;13(24):6667-80

State Key Laboratory of Synthetic Chemistry and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1039/c5ob00407aDOI Listing
June 2015

Calorie Restriction Prevents Metabolic Aging Caused by Abnormal SIRT1 Function in Adipose Tissues.

Diabetes 2015 May 4;64(5):1576-90. Epub 2014 Dec 4.

State Key Laboratory of Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China

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May 2015

Pincer-Type Platinum(II) Complexes Containing N-Heterocyclic Carbene (NHC) Ligand: Structures, Photophysical and Anion-Binding Properties, and Anticancer Activities.

Chemistry 2015 May 1;21(20):7441-53. Epub 2015 Apr 1.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P.R. China), Fax: (+852) 2915-5176; HKU Shenzhen Institute of Research and Innovation, Shenzhen 518053 (P.R. China).

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May 2015

A luminescent cyclometalated gold(iii)-avidin conjugate with a long-lived emissive excited state that binds to proteins and DNA and possesses anti-proliferation capacity.

Chem Commun (Camb) 2015 May;51(40):8547-50

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, Chemical Biology Center and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

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May 2015

Theoretical studies on the photophysical properties of luminescent pincer gold(iii) arylacetylide complexes: the role of π-conjugation at the C-deprotonated [C^N^C] ligand.

Chem Sci 2015 May 10;6(5):3026-3037. Epub 2015 Mar 10.

State Key Laboratory of Synthetic Chemistry , Institute of Molecular Functional Materials , Department of Chemistry , The University of Hong Kong , Pokfulam Road , Hong Kong SAR , China . Email: ; Email:

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http://dx.doi.org/10.1039/c4sc03697bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795471PMC
May 2015

Phosphorescent organoplatinum(II) complexes with a lipophilic anion: supramolecular soft nanomaterials through ionic self-assembly and metallophilicity.

Chem Commun (Camb) 2015 Mar;51(25):5371-4

State Key Laboratory of Synthetic Chemistry, HKU-CAS Joint Laboratory on New Materials, and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China.

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http://dx.doi.org/10.1039/c4cc08569hDOI Listing
March 2015

Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview.

Nat Prod Rep 2015 Feb;32(2):256-72

State Key Laboratory of Oncogenes and Related Genes, and School of Biological Sciences, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1039/c4np00080cDOI Listing
February 2015

Anti-cancer iron(II) complexes of pentadentate N-donor ligands: cytotoxicity, transcriptomics analyses, and mechanisms of action.

Chemistry 2015 Feb 17;21(7):3062-72. Epub 2014 Dec 17.

State Key Laboratory of Synthetic Chemistry, Department of Chemistry and Chemical Biology Centre, The University of Hong Kong, Pokfulam Road, Hong Kong (PR China).

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http://dx.doi.org/10.1002/chem.201404749DOI Listing
February 2015

Self-assembly of functional molecules into 1D crystalline nanostructures.

Adv Mater 2015 Feb 18;27(6):985-1013. Epub 2014 Dec 18.

CAS Key Laboratory of Organic Solids, Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, People's Republic of China.

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http://doi.wiley.com/10.1002/adma.201403846
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February 2015

Luminescent pincer platinum(II) complexes with emission quantum yields up to almost unity: photophysics, photoreductive C-C bond formation, and materials applications.

Angew Chem Int Ed Engl 2015 Feb 9;54(7):2084-9. Epub 2015 Jan 9.

State Key Laboratory of Synthetic Chemistry, Institute of Molecular Functional Materials, HKU-CAS Joint Laboratory on New Materials, Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P.R. China).

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http://dx.doi.org/10.1002/anie.201408940DOI Listing
February 2015

[Fe(F20 TPP)Cl]-catalyzed amination with arylamines and {[Fe(F20 TPP)(NAr)](PhI=NAr)} + . Intermediate assessed by high-resolution ESI-MS and DFT calculations.

Chem Asian J 2015 Jan 11;10(1):100-5. Epub 2014 Sep 11.

Department of Chemistry, State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P. R. China), Fax: (+852) 2857-1586.

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http://dx.doi.org/10.1002/asia.201402580DOI Listing
January 2015

Long-lived excited states of zwitterionic copper(I) complexes for photoinduced cross-dehydrogenative coupling reactions.

Chemistry 2015 Jan 20;21(3):1184-90. Epub 2014 Nov 20.

Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Key Laboratory of Inorganic-Organic Hybrid Functional Materials Chemistry, Ministry of Education, College of Chemistry, Tianjin Normal University, Tianjin 300387 (China).

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http://dx.doi.org/10.1002/chem.201405356DOI Listing
January 2015

Phosphorescent cyclometalated iridium(III) complexes that contain substituted 2-acetylbenzo[b]thiophen-3-olate ligand for red organic light-emitting devices.

Chem Asian J 2014 Dec 8;9(12):3572-85. Epub 2014 Oct 8.

HKU-CAS Joint Laboratory on New Materials and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, Fax: (+852) 2915-5176; HKU Shenzhen Institute of Research and Innovation, Shenzhen 518053 (China).

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http://dx.doi.org/10.1002/asia.201402782DOI Listing
December 2014

Ruthenium-porphyrin-catalyzed diastereoselective intramolecular alkyl carbene insertion into C-H bonds of alkyl diazomethanes generated in situ from N-tosylhydrazones.

Angew Chem Int Ed Engl 2014 Dec 15;53(51):14175-80. Epub 2014 Oct 15.

HKU Shenzhen Institute of Research and Innovation, Shenzhen (China); State Key Laboratory of Synthetic Chemistry and Department of Chemistry, The University of Hong Kong, Hong Kong (China).

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http://dx.doi.org/10.1002/anie.201408102DOI Listing
December 2014

A cancer-targeted nanosystem for delivery of gold(III) complexes: enhanced selectivity and apoptosis-inducing efficacy of a gold(III) porphyrin complex.

Angew Chem Int Ed Engl 2014 Nov 12;53(46):12532-6. Epub 2014 Sep 12.

Department of Chemistry, Jinan University, Guangzhou 510632 (China).

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http://doi.wiley.com/10.1002/anie.201407143
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November 2014

Straightforward installation of carbon-halogen, carbon-oxygen and carbon-carbon bonds within metal-organic frameworks (MOF) via palladium-catalysed direct C-H functionalization.

Chem Commun (Camb) 2014 Nov 18;50(87):13261-4. Epub 2014 Sep 18.

ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, P. R. China.

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November 2014

Density functional theory calculations on oxidative C-C bond cleavage and N-O bond formation of [Ru(II)(bpy)2(diamine)](2+) via reactive ruthenium imide intermediates.

Chemistry 2014 Nov 29;20(46):15122-30. Epub 2014 Sep 29.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road (Hong Kong), Fax: (+852) 2857-1586.

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http://dx.doi.org/10.1002/chem.201402517DOI Listing
November 2014

Designed synthesis of a highly conjugated hexaethynylbenzene-based host for supramolecular architectures.

Chem Asian J 2014 Oct 8;9(10):2842-9. Epub 2014 Aug 8.

CAS Key Laboratory of Organic Solids, Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (P.R. China), Fax: (+86) 10-82616576.

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October 2014

Efficient red electroluminescent devices with sterically hindered phosphorescent platinum(II) Schiff base complexes and iridium complex codopant.

Chem Asian J 2014 Oct 21;9(10):2984-94. Epub 2014 Aug 21.

State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (P.R. China).

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http://dx.doi.org/10.1002/asia.201402618DOI Listing
October 2014

[Fe(III)(TF4DMAP)OTf] catalysed anti-Markovnikov oxidation of terminal aryl alkenes to aldehydes and transformation of methyl aryl tertiary amines to formamides with H2O2 as a terminal oxidant.

Chem Commun (Camb) 2014 Oct;50(84):12669-72

Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, 354 Feng Lin Road, Shanghai, China.

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http://dx.doi.org/10.1039/c4cc05972gDOI Listing
October 2014

Alkenyl/thiol-derived metal-organic frameworks (MOFs) by means of postsynthetic modification for effective mercury adsorption.

Chemistry 2014 Oct 10;20(43):14090-5. Epub 2014 Sep 10.

ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058 (P.R. China), Fax: (+86) 571-88981051.

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http://dx.doi.org/10.1002/chem.201403382DOI Listing
October 2014

Ruthenium porphyrins with axial π-conjugated arylamide and arylimide ligands.

Chemistry 2014 Aug 25;20(35):11035-47. Epub 2014 Jul 25.

Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong (P. R. China).

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http://dx.doi.org/10.1002/chem.201305084DOI Listing
August 2014