Publications by authors named "Chi Van Le"

4 Publications

  • Page 1 of 1

Lidocaine-induced systemic toxicity complicating radiofrequency ablation of benign thyroid nodule procedure: A case report and review of literature.

Clin Case Rep 2021 Oct 10;9(10):e04910. Epub 2021 Oct 10.

Department of Internal Medicine Hue University of Medicine and Pharmacy Hue University Hue City Vietnam.

The systemic toxicity of lidocaine is an extremely rare complication of thyroid RFA procedure, and it can be life-threatening. The quick recognization of its symptoms and intravenous use of lipid emulsion are essential to preventing mortality.
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http://dx.doi.org/10.1002/ccr3.4910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502456PMC
October 2021

Efficacy and Safety of Single-Session Radiofrequency Ablation in Treating Benign Thyroid Nodules: A Short-Term Prospective Cohort Study.

Int J Endocrinol 2021 11;2021:7556393. Epub 2021 Sep 11.

Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam.

Objective: The aims of this study are to evaluate the safety and efficacy of RFA in the treatment of benign thyroid nodule(s) and to find independent factors related to the volume reduction rate of the nodule(s).

Materials And Methods: This short-term prospective study from a single medical center was conducted on 93 benign thyroid nodules in 93 patients treated with RFA. Two basic techniques were used: the trans-isthmic approach and moving-shot technique. Clinical and ultrasonography examinations were performed at 1- and 3-month follow-up after the treatment session. Primary outcomes included volume reduction ratio (VRR) at 1-month and 3-month follow-ups; secondary outcomes were therapeutic success rate and complications. Multiple linear regression analysis was used to determine independent factors associated with VRR.

Results: A final sample of 78 patients with 78 nodules, given participant rate 83.8% (including 60 solid nodules, 16 predominantly cystic nodules, and 2 thyroid cysts), was followed up for 3 months. The mean volume reduction ratio was 41.47% and 64.72% after 1-month and 3-month follow-ups, respectively. The therapeutic success rate was 30.8% at 1-month and 84.6% at 3-month follow-ups. Symptom score and cosmetic score improved significantly. There was no change in thyroid function tests. Two minor complications (transient voice change) were found. The multiple linear regression analysis showed that the internal component of the nodules significantly related to the VRR during the 3-month follow-up ( = 23.00; 95%CI (7.59-38.45)).

Conclusion: RFA was demonstrated as a safe and effective option for benign thyroid nodules treatment. It can be used as an alternative treatment with encouraging results.
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http://dx.doi.org/10.1155/2021/7556393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452432PMC
September 2021

Diabetes-Related Distress and Its Associated Factors Among Patients with Diabetes in Vietnam.

Psychol Res Behav Manag 2020 14;13:1181-1189. Epub 2020 Dec 14.

Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam.

Background: Psychometric properties are regarded as one of the significant contributors related to diabetes treatment efficacy. Diabetes-related distress (DD) is one of the emotional burdens. The aims of this study were to investigate the prevalence of DD and to determine its associated factors among Vietnamese diabetic patients.

Methods: A cross-sectional study was conducted at a single medical center in the central of Vietnam. A total of 138 eligible DM outpatients were invited and a total of 112 patients who completed the questionnaire were utilized in this analysis using convenience sampling. DD was assessed using the diabetes distress scale (DDS). The participant's sociodemographic and clinical information was obtained through face-to-face interviews and medical records. Multivariate logistic regression was used to determine independent factors associated with the presence of DD.

Results: Approximately, 12.5% of the patients experienced DD based on DDS self-administered questionnaire. The rates of mild/moderate and high distress were 8.0% and 4.5%, respectively. DD was found to be significantly higher in type 1 DM (p=0.04), insulin only in treatment regime (p=0.04), physical inactivities (p=0.02), times of mild hypoglycemia (time/month) (p=0.01), and fasting plasma glucose (mmol/l) (p=0.04). The occurrence of distress among DM patients was negatively correlated with their age and amount of physical exercise. Meanwhile, poor HbA1c control (HbA1c≥7%) was associated with an increased occurrence of diabetes distress.

Conclusion: The findings of single medical center in Vietnam highlights that DD is prevalent among DM patients. It should be of marked concerns, particularly the type 1 diabetic patients, younger age, and poor glycemic control patients.
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http://dx.doi.org/10.2147/PRBM.S285291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754255PMC
December 2020

Undifferentiated pleomorphic sarcoma of the thyroid: A case report and ƚiterature review.

Clin Case Rep 2020 Apr 11;8(4):680-684. Epub 2020 Feb 11.

Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine Asan Medical Center Seoul Korea.

This report describes a patient who presented with a large thyroid nodule and compressive symptoms. Immunohistochemical staining showed diffuse marked reactivity for vimentin and focal reactivity for CD68 and Ki-67 that is compatible with primary undifferentiated pleomorphic sarcoma of the thyroid. This report emphasizes and discusses extremely rare thyroid cancer type.
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http://dx.doi.org/10.1002/ccr3.2710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141736PMC
April 2020
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