Chi Pui Pang

Chi Pui Pang

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Chi Pui Pang

Publications by authors named "Chi Pui Pang"

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Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress.

Mol Neurobiol 2019 Sep 22;56(9):6586-6593. Epub 2019 Mar 22.

Department of Ophthalmology and Visual Sciences, Hong Kong Eye Hospital, The Chinese University of Hong Kong, 147K Argyle Street, Kowloon, Hong Kong.

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http://dx.doi.org/10.1007/s12035-019-1559-5DOI Listing
September 2019

Caveolin-1 regulates human trabecular meshwork cell adhesion, endocytosis, and autophagy.

J Cell Biochem 2019 Aug 27;120(8):13382-13391. Epub 2019 Mar 27.

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.

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http://dx.doi.org/10.1002/jcb.28613DOI Listing
August 2019

A sclerocornea-associated RAD21 variant induces corneal stroma disorganization.

Exp Eye Res 2019 Aug 5;185:107687. Epub 2019 Jun 5.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong; Shantou University/Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China.

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http://dx.doi.org/10.1016/j.exer.2019.06.001DOI Listing
August 2019

Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration.

Exp Eye Res 2019 Aug 1;187:107748. Epub 2019 Aug 1.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2019.107748DOI Listing
August 2019

Association of the and genes with myopia of different severities.

Br J Ophthalmol 2019 Jul 12. Epub 2019 Jul 12.

Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, New Territories, Hong Kong

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http://dx.doi.org/10.1136/bjophthalmol-2019-314203DOI Listing
July 2019

Green Tea Extract Ameliorates Ischemia-Induced Retinal Ganglion Cell Degeneration in Rats.

Oxid Med Cell Longev 2019 9;2019:8407206. Epub 2019 Jul 9.

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.

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http://dx.doi.org/10.1155/2019/8407206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652088PMC
July 2019

Integrating opportunistic glaucoma screening into general health examinations in China: A pilot study.

Clin Exp Ophthalmol 2019 May 31. Epub 2019 May 31.

Department of Ophthalmology, the Fourth Peoples' Hospital of Shenyang, Shenyang Key Lab of Ophthalmology, Liaoning, China.

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http://dx.doi.org/10.1111/ceo.13564DOI Listing
May 2019

Coding Region Mutation Screening in Optineurin in Chinese Normal-Tension Glaucoma Patients.

Dis Markers 2019 6;2019:5820537. Epub 2019 May 6.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1155/2019/5820537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526575PMC
May 2019

Elevated bone morphogenic protein 4 expression implicated in site-specific adipogenesis in thyroid associated orbitopathy.

Exp Eye Res 2019 Apr 2;181:185-189. Epub 2019 Feb 2.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, 4/F, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong, China; Department of Ophthalmology and Visual Sciences, 1/F, Eye Centre, Prince of Wales Hospital, 30-32 Ngan Shing St, Sha Tin, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2019.01.020DOI Listing
April 2019

Growth hormone-releasing hormone receptor mediates cytokine production in ciliary and iris epithelial cells during LPS-induced ocular inflammation.

Exp Eye Res 2019 Apr 1;181:277-284. Epub 2019 Mar 1.

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2019.02.021DOI Listing
April 2019

Mutant RAMP2 causes primary open-angle glaucoma via the CRLR-cAMP axis.

Genet Med 2019 Apr 19. Epub 2019 Apr 19.

The Key Laboratory for Human Disease Gene Study of Sichuan Province and Department of Laboratory Medicine, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.

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http://www.nature.com/articles/s41436-019-0507-0
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http://dx.doi.org/10.1038/s41436-019-0507-0DOI Listing
April 2019

Continuous exposure of nicotine and cotinine retards human primary pterygium cell proliferation and migration.

J Cell Biochem 2019 Mar 27;120(3):4203-4213. Epub 2018 Sep 27.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://doi.wiley.com/10.1002/jcb.27707
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http://dx.doi.org/10.1002/jcb.27707DOI Listing
March 2019

Association of the SIX6 locus with primary open angle glaucoma in southern Chinese and Japanese.

Exp Eye Res 2019 03 23;180:129-136. Epub 2018 Dec 23.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144835183083
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http://dx.doi.org/10.1016/j.exer.2018.12.014DOI Listing
March 2019

Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population.

Sci China Life Sci 2019 Feb 24;62(2):153-164. Epub 2018 Dec 24.

The Key Laboratory for Human Disease Gene Study of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China.

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http://link.springer.com/10.1007/s11427-018-9430-2
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http://dx.doi.org/10.1007/s11427-018-9430-2DOI Listing
February 2019

Vitamin D and its pathway genes in myopia: systematic review and meta-analysis.

Br J Ophthalmol 2019 01 17;103(1):8-17. Epub 2018 Jul 17.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China

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http://dx.doi.org/10.1136/bjophthalmol-2018-312159DOI Listing
January 2019

MicroRNA-132 directs human periodontal ligament-derived neural crest stem cell neural differentiation.

J Tissue Eng Regen Med 2019 Jan 17;13(1):12-24. Epub 2018 Dec 17.

Geriatric Research, Education and Clinical Center, Miami Veterans Affairs Medical Center, Miami, Florida.

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http://doi.wiley.com/10.1002/term.2759
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http://dx.doi.org/10.1002/term.2759DOI Listing
January 2019

Analysis of multiple genetic loci reveals rs1324183 as a putative genetic marker for keratoconus.

Br J Ophthalmol 2018 12 12;102(12):1736-1741. Epub 2018 Jul 12.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China

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http://dx.doi.org/10.1136/bjophthalmol-2018-312218DOI Listing
December 2018

Casein kinase-II inhibition promotes retinal ganglion cell survival and axonal regeneration.

Exp Eye Res 2018 12 15;177:153-159. Epub 2018 Aug 15.

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1016/j.exer.2018.08.010DOI Listing
December 2018

Metabolomics of Green-Tea Catechins on Vascular-Endothelial-Growth-Factor-Stimulated Human-Endothelial-Cell Survival.

J Agric Food Chem 2018 Dec 27;66(48):12866-12875. Epub 2018 Nov 27.

Department of Ophthalmology and Visual Sciences , The Chinese University of Hong Kong, Hong Kong Eye Hospital , Kowloon , Hong Kong.

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http://pubs.acs.org/doi/10.1021/acs.jafc.8b05998
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http://dx.doi.org/10.1021/acs.jafc.8b05998DOI Listing
December 2018

Improving the quality of electroretinogram recordings using active electrodes.

Exp Eye Res 2018 11 14;176:46-52. Epub 2018 Jun 14.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China; Shantou University/Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2018.06.007DOI Listing
November 2018

The Evolving Story of Pterygium.

Cornea 2018 Nov;37 Suppl 1:S55-S57

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1097/ICO.0000000000001744DOI Listing
November 2018

p53 inhibition by MDM2 in human pterygium.

Exp Eye Res 2018 10 19;175:142-147. Epub 2018 Jun 19.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2018.06.021DOI Listing
October 2018

Association of coding and UTR variants in the known regions with wet age-related macular degeneration in Han Chinese population.

J Hum Genet 2018 Oct 19;63(10):1055-1070. Epub 2018 Jul 19.

Sichuan Provincial Key Laboratory for Human Disease Gene Study and the Department of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.

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http://dx.doi.org/10.1038/s10038-018-0490-3DOI Listing
October 2018

Notch Signaling Activation Enhances Human Adipose-Derived Stem Cell Retinal Differentiation.

Stem Cells Int 2018 16;2018:9201374. Epub 2018 Oct 16.

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, China.

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http://dx.doi.org/10.1155/2018/9201374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206515PMC
October 2018

Depot-specific characteristics of adipose tissue-derived stromal cells in thyroid-associated orbitopathy.

Br J Ophthalmol 2018 08 17;102(8):1173-1178. Epub 2018 Apr 17.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China

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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2017-3113
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http://dx.doi.org/10.1136/bjophthalmol-2017-311339DOI Listing
August 2018

Human Periodontal Ligament-Derived Stem Cells Promote Retinal Ganglion Cell Survival and Axon Regeneration After Optic Nerve Injury.

Stem Cells 2018 06 7;36(6):844-855. Epub 2018 Mar 7.

Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, People's Republic of China.

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http://dx.doi.org/10.1002/stem.2812DOI Listing
June 2018

Cellular Proliferation and Migration of Human Pterygium Cells: Mitomycin Versus Small-Molecule Inhibitors.

Cornea 2018 Jun;37(6):760-766

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong.

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http://Insights.ovid.com/crossref?an=00003226-201806000-0001
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http://dx.doi.org/10.1097/ICO.0000000000001569DOI Listing
June 2018

Quantitative retinal microvasculature in children using swept-source optical coherence tomography: the Hong Kong Children Eye Study.

Br J Ophthalmol 2018 Jun 28. Epub 2018 Jun 28.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Sha Tin, Hong Kong

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http://dx.doi.org/10.1136/bjophthalmol-2018-312413DOI Listing
June 2018

MicroRNA regulation of MDM2-p53 loop in pterygium.

Exp Eye Res 2018 04 31;169:149-156. Epub 2018 Jan 31.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2018.01.015DOI Listing
April 2018

Association of the gene with extreme myopia rather than lower grade myopias.

Br J Ophthalmol 2018 04 7;102(4):570-574. Epub 2018 Feb 7.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1136/bjophthalmol-2017-311327DOI Listing
April 2018

Detection of mutations in MYOC, OPTN, NTF4, WDR36 and CYP1B1 in Chinese juvenile onset open-angle glaucoma using exome sequencing.

Sci Rep 2018 03 14;8(1):4498. Epub 2018 Mar 14.

Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, P. R. China.

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http://dx.doi.org/10.1038/s41598-018-22337-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852028PMC
March 2018

Effectiveness of meibomian gland massage combined with topical levofloxacin against ocular surface flora in patients before penetrating ocular surgery.

Ocul Surf 2018 01 7;16(1):70-76. Epub 2017 Sep 7.

Department of Ophthalmology, The Fourth People's Hospital of Shenyang, Shenyang Eye Research Institute, Key Laboratory of Ophthalmology of Shenyang, China. Electronic address:

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http://dx.doi.org/10.1016/j.jtos.2017.09.001DOI Listing
January 2018

Green tea extract attenuates LPS-induced retinal inflammation in rats.

Sci Rep 2018 01 11;8(1):429. Epub 2018 Jan 11.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

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http://dx.doi.org/10.1038/s41598-017-18888-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765135PMC
January 2018

Expression profiling of the retina of pde6c, a zebrafish model of retinal degeneration.

Sci Data 2017 12 12;4:170182. Epub 2017 Dec 12.

Department of Statistics, University of Georgia, 101 Cedar St, Athens, GA 30602, USA.

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http://dx.doi.org/10.1038/sdata.2017.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726315PMC
December 2017

Novel Mutations in PRPF31 Causing Retinitis Pigmentosa Identified Using Whole-Exome Sequencing.

Invest Ophthalmol Vis Sci 2017 12;58(14):6342-6350

Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China.

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http://dx.doi.org/10.1167/iovs.17-22952DOI Listing
December 2017

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.

Invest Ophthalmol Vis Sci 2017 08;58(10):4384–4389

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1167/iovs.17-22304DOI Listing
August 2017

Quantitative Characterization of Autoimmune Uveoretinitis in an Experimental Mouse Model.

Invest Ophthalmol Vis Sci 2017 08;58(10):4193-4200

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1167/iovs.17-22436DOI Listing
August 2017

A γA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid.

PLoS One 2016 11;11(8):e0160691. Epub 2016 Aug 11.

School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160691PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981419PMC
July 2017

Utilizing Zebrafish Visual Behaviors in Drug Screening for Retinal Degeneration.

Int J Mol Sci 2017 Jun 2;18(6). Epub 2017 Jun 2.

Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou 515041, China.

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http://dx.doi.org/10.3390/ijms18061185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486008PMC
June 2017

Statistical Analysis of Zebrafish Locomotor Behaviour by Generalized Linear Mixed Models.

Sci Rep 2017 06 7;7(1):2937. Epub 2017 Jun 7.

Department of Biological Sciences, Purdue University, 915 W. State Street, West Lafayette, IN, 47907, USA.

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http://dx.doi.org/10.1038/s41598-017-02822-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462837PMC
June 2017

Disruption of retinal pigment epithelial cell properties under the exposure of cotinine.

Sci Rep 2017 06 9;7(1):3139. Epub 2017 Jun 9.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1038/s41598-017-03283-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466671PMC
June 2017

Bacteriological profile of ocular surface flora in meibomian gland dysfunction.

Ocul Surf 2017 04 14;15(2):242-247. Epub 2017 Jan 14.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1016/j.jtos.2016.12.003DOI Listing
April 2017

Cardiomyogenesis of periodontal ligament-derived stem cells by dynamic tensile strain.

Cell Tissue Res 2017 02 17;367(2):229-241. Epub 2016 Oct 17.

Department of Biomedical Engineering, College of Engineering, University of Miami, Coral Gables, FL, USA.

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http://dx.doi.org/10.1007/s00441-016-2503-xDOI Listing
February 2017

AAV-mediated transfer of RhoA shRNA and CNTF promotes retinal ganglion cell survival and axon regeneration.

Neuroscience 2017 02 23;343:472-482. Epub 2016 Dec 23.

Joint Shantou International Eye Center, Shantou University and The Chinese University of Hong Kong, Shantou, PR China; Department of Neurology, Affiliated Hospital of Hubei University for Nationalities, Enshi, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2016.12.027DOI Listing
February 2017

Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations.

Invest Ophthalmol Vis Sci 2017 02;58(2):1076-1083

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China 3Shantou University/The Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China 4Prince of Wales Hospital Eye Centre, Hong Kong, China.

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http://dx.doi.org/10.1167/iovs.16-20575DOI Listing
February 2017

Genetics of Bietti Crystalline Dystrophy.

Asia Pac J Ophthalmol (Phila) 2016 Jul-Aug;5(4):245-52

From the *Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong; and †2010 Retina and Macula Centre, Kowloon, Hong Kong.

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http://dx.doi.org/10.1097/APO.0000000000000209DOI Listing
January 2017

Molecular Genomics of Eye Diseases.

Authors:
Chi Pui Pang

Asia Pac J Ophthalmol (Phila) 2016 Jul-Aug;5(4):225-6

From the Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Kowloon, Hong Kong.

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http://dx.doi.org/10.1097/APO.0000000000000221DOI Listing
January 2017

Myopia Genetics-The Asia-Pacific Perspective.

Asia Pac J Ophthalmol (Phila) 2016 Jul-Aug;5(4):236-44

From the *Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong; and †Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/APO.0000000000000224DOI Listing
January 2017

Protective effects of an HTRA1 insertion-deletion variant against age-related macular degeneration in the Chinese populations.

Lab Invest 2017 01 14;97(1):43-52. Epub 2016 Nov 14.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Kowloon, Hong Kong.

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http://dx.doi.org/10.1038/labinvest.2016.117DOI Listing
January 2017

Differentiation potential of human adipose tissue derived stem cells into photoreceptors through explants culture and enzyme methods.

Int J Ophthalmol 2017 18;10(1):23-29. Epub 2017 Jan 18.

Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong 999077, China.

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http://dx.doi.org/10.18240/ijo.2017.01.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225344PMC
January 2017

Antagonists of growth hormone-releasing hormone receptor induce apoptosis specifically in retinoblastoma cells.

Proc Natl Acad Sci U S A 2016 12 23;113(50):14396-14401. Epub 2016 Nov 23.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong;

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http://dx.doi.org/10.1073/pnas.1617427113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167144PMC
December 2016

Novel compound heterozygous mutation in the CNGA1 gene underlie autosomal recessive retinitis pigmentosa in a Chinese family.

Biosci Rep 2016 22;36(1):e00289. Epub 2016 Jan 22.

Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing 400038, China Department of Ophthalmology, General Hospital of Chinese PLA, Beijing 100853, China Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing 400038, China

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http://www.bioscirep.org/content/36/1/e00289.full.pdf
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http://bioscirep.org/cgi/doi/10.1042/BSR20150131
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http://dx.doi.org/10.1042/BSR20150131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725244PMC
October 2016

Association of ABCG1 With Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Chinese and Japanese.

Invest Ophthalmol Vis Sci 2016 Oct;57(13):5758-5763

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China 4Joint Shantou International Eye Center, Shantou, China 5Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.16-20175DOI Listing
October 2016

Green tea catechins are potent anti-oxidants that ameliorate sodium iodate-induced retinal degeneration in rats.

Sci Rep 2016 07 7;6:29546. Epub 2016 Jul 7.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1038/srep29546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935886PMC
July 2016

Statistical Analysis of Zebrafish Locomotor Response.

PLoS One 2015 5;10(10):e0139521. Epub 2015 Oct 5.

Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine Lafayette, West Lafayette, Indiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139521PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593604PMC
June 2016

Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-analysis.

Ophthalmology 2016 06 4;123(6):1211-21. Epub 2016 Feb 4.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2015.12.027DOI Listing
June 2016

Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts.

PLoS Genet 2016 06 13;12(6):e1006090. Epub 2016 Jun 13.

Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou, China.

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http://dx.doi.org/10.1371/journal.pgen.1006090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905677PMC
June 2016

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.

Authors:
Chiea Chuen Khor Tan Do Hongyan Jia Masakazu Nakano Ronnie George Khaled Abu-Amero Roopam Duvesh Li Jia Chen Zheng Li Monisha E Nongpiur Shamira A Perera Chunyan Qiao Hon-Tym Wong Hiroshi Sakai Mônica Barbosa de Melo Mei-Chin Lee Anita S Chan Yaakub Azhany Thi Lam Huong Dao Yoko Ikeda Rodolfo A Perez-Grossmann Tomasz Zarnowski Alexander C Day Jost B Jonas Pancy O S Tam Tuan Anh Tran Humaira Ayub Farah Akhtar Shazia Micheal Paul T K Chew Leyla A Aljasim Tanuj Dada Tam Thi Luu Mona S Awadalla Naris Kitnarong Boonsong Wanichwecharungruang Yee Yee Aung Jelinar Mohamed-Noor Saravanan Vijayan Sripriya Sarangapani Rahat Husain Aliza Jap Mani Baskaran David Goh Daniel H Su Huaizhou Wang Vernon K Yong Leonard W Yip Tuyet Bach Trinh Manchima Makornwattana Thanh Thu Nguyen Edgar U Leuenberger Ki-Ho Park Widya Artini Wiyogo Rajesh S Kumar Celso Tello Yasuo Kurimoto Suman S Thapa Kessara Pathanapitoon John F Salmon Yong Ho Sohn Antonio Fea Mineo Ozaki Jimmy S M Lai Visanee Tantisevi Chaw Chaw Khaing Takanori Mizoguchi Satoko Nakano Chan-Yun Kim Guangxian Tang Sujie Fan Renyi Wu Hailin Meng Thi Thuy Giang Nguyen Tien Dat Tran Morio Ueno Jose Maria Martinez Norlina Ramli Yin Mon Aung Rigo Daniel Reyes Stephen A Vernon Seng Kheong Fang Zhicheng Xie Xiao Yin Chen Jia Nee Foo Kar Seng Sim Tina T Wong Desmond T Quek Rengaraj Venkatesh Srinivasan Kavitha Subbiah R Krishnadas Nagaswamy Soumittra Balekudaru Shantha Boon-Ang Lim Jeanne Ogle José P C de Vasconcellos Vital P Costa Ricardo Y Abe Bruno B de Souza Chelvin C Sng Maria C Aquino Ewa Kosior-Jarecka Guillermo Barreto Fong Vania Castro Tamanaja Ricardo Fujita Yuzhen Jiang Naushin Waseem Sancy Low Huan Nguyen Pham Sami Al-Shahwan E Randy Craven Muhammad Imran Khan Rrima Dada Kuldeep Mohanty Muneeb A Faiq Alex W Hewitt Kathryn P Burdon Eng Hui Gan Anuwat Prutthipongsit Thipnapa Patthanathamrongkasem Mary Ann T Catacutan Irene R Felarca Chona S Liao Emma Rusmayani Vira Wardhana Istiantoro Giulia Consolandi Giulia Pignata Carlo Lavia Prin Rojanapongpun Lerprat Mangkornkanokpong Sunee Chansangpetch Jonathan C H Chan Bonnie N K Choy Jennifer W H Shum Hlaing May Than Khin Thida Oo Aye Thi Han Victor H Yong Xiao-Yu Ng Shuang Ru Goh Yaan Fun Chong Martin L Hibberd Mark Seielstad Eileen Png Sarah J Dunstan Nguyen Van Vinh Chau Jinxin Bei Yi Xin Zeng Abhilasha Karkey Buddha Basnyat Francesca Pasutto Daniela Paoli Paolo Frezzotti Jie Jin Wang Paul Mitchell John H Fingert R Rand Allingham Michael A Hauser Soon Thye Lim Soo Hong Chew Richard P Ebstein Anavaj Sakuntabhai Kyu Hyung Park Jeeyun Ahn Greet Boland Harm Snippe Richard Stead Raquel Quino Su Nyunt Zaw Urszula Lukasik Rohit Shetty Mimiwati Zahari Hyoung Won Bae Nay Lin Oo Toshiaki Kubota Anita Manassakorn Wing Lau Ho Laura Dallorto Young Hoon Hwang Christine A Kiire Masako Kuroda Zeiras Eka Djamal Jovell Ian M Peregrino Arkasubhra Ghosh Jin Wook Jeoung Tung S Hoan Nuttamon Srisamran Thayanithi Sandragasu Saw Htoo Set Vi Huyen Doan Shomi S Bhattacharya Ching-Lin Ho Donald T Tan Ramanjit Sihota Seng-Chee Loon Kazuhiko Mori Shigeru Kinoshita Anneke I den Hollander Raheel Qamar Ya-Xing Wang Yik Y Teo E-Shyong Tai Curt Hartleben-Matkin David Lozano-Giral Seang Mei Saw Ching-Yu Cheng Juan C Zenteno Chi Pui Pang Huong T T Bui Owen Hee Jamie E Craig Deepak P Edward Michiko Yonahara Jamil Miguel Neto Maria L Guevara-Fujita Liang Xu Robert Ritch Ahmad Tajudin Liza-Sharmini Tien Y Wong Saleh Al-Obeidan Nhu Hon Do Periasamy Sundaresan Clement C Tham Paul J Foster Lingam Vijaya Kei Tashiro Eranga N Vithana Ningli Wang Tin Aung

Nat Genet 2016 May 4;48(5):556-62. Epub 2016 Apr 4.

Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.

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May 2016

Identification of PGF as a New Gene for Neovascular Age-Related Macular Degeneration in a Chinese Population.

Invest Ophthalmol Vis Sci 2016 Apr;57(4):1714-20

Department of Ophthalmology & Visual Sciences The Chinese University of Hong Kong, Hong Kong 2Department of Ophthalmology & Visual Sciences, Prince of Wales Hospital, Hong Kong 3Joint Shantou International Eye Centre, Shantou, China.

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April 2016

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.

Authors:
Qiao Fan Virginie J M Verhoeven Robert Wojciechowski Veluchamy A Barathi Pirro G Hysi Jeremy A Guggenheim René Höhn Veronique Vitart Anthony P Khawaja Kenji Yamashiro S Mohsen Hosseini Terho Lehtimäki Yi Lu Toomas Haller Jing Xie Cécile Delcourt Mario Pirastu Juho Wedenoja Puya Gharahkhani Cristina Venturini Masahiro Miyake Alex W Hewitt Xiaobo Guo Johanna Mazur Jenifer E Huffman Katie M Williams Ozren Polasek Harry Campbell Igor Rudan Zoran Vatavuk James F Wilson Peter K Joshi George McMahon Beate St Pourcain David M Evans Claire L Simpson Tae-Hwi Schwantes-An Robert P Igo Alireza Mirshahi Audrey Cougnard-Gregoire Céline Bellenguez Maria Blettner Olli Raitakari Mika Kähönen Ilkka Seppala Tanja Zeller Thomas Meitinger Janina S Ried Christian Gieger Laura Portas Elisabeth M van Leeuwen Najaf Amin André G Uitterlinden Fernando Rivadeneira Albert Hofman Johannes R Vingerling Ya Xing Wang Xu Wang Eileen Tai-Hui Boh M Kamran Ikram Charumathi Sabanayagam Preeti Gupta Vincent Tan Lei Zhou Candice E H Ho Wan'e Lim Roger W Beuerman Rosalynn Siantar E-Shyong Tai Eranga Vithana Evelin Mihailov Chiea-Chuen Khor Caroline Hayward Robert N Luben Paul J Foster Barbara E K Klein Ronald Klein Hoi-Suen Wong Paul Mitchell Andres Metspalu Tin Aung Terri L Young Mingguang He Olavi Pärssinen Cornelia M van Duijn Jie Jin Wang Cathy Williams Jost B Jonas Yik-Ying Teo David A Mackey Konrad Oexle Nagahisa Yoshimura Andrew D Paterson Norbert Pfeiffer Tien-Yin Wong Paul N Baird Dwight Stambolian Joan E Bailey Wilson Ching-Yu Cheng Christopher J Hammond Caroline C W Klaver Seang-Mei Saw Jugnoo S Rahi Jean-François Korobelnik John P Kemp Nicholas J Timpson George Davey Smith Jamie E Craig Kathryn P Burdon Rhys D Fogarty Sudha K Iyengar Emily Chew Sarayut Janmahasatian Nicholas G Martin Stuart MacGregor Liang Xu Maria Schache Vinay Nangia Songhomitra Panda-Jonas Alan F Wright Jeremy R Fondran Jonathan H Lass Sheng Feng Jing Hua Zhao Kay-Tee Khaw Nick J Wareham Taina Rantanen Jaakko Kaprio Chi Pui Pang Li Jia Chen Pancy O Tam Vishal Jhanji Alvin L Young Angela Döring Leslie J Raffel Mary-Frances Cotch Xiaohui Li Shea Ping Yip Maurice K H Yap Ginevra Biino Simona Vaccargiu Maurizio Fossarello Brian Fleck Seyhan Yazar Jan Willem L Tideman Milly Tedja Margaret M Deangelis Margaux Morrison Lindsay Farrer Xiangtian Zhou Wei Chen Nobuhisa Mizuki Akira Meguro Kari Matti Mäkelä

Nat Commun 2016 Mar 29;7:11008. Epub 2016 Mar 29.

Department of Ophthalmology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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March 2016

Computational classification of different wild-type zebrafish strains based on their variation in light-induced locomotor response.

Comput Biol Med 2016 Feb 30;69:1-9. Epub 2015 Nov 30.

Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou, China. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2015.11.012DOI Listing
February 2016

Association of toll-like receptor 3 polymorphism rs3775291 with age-related macular degeneration: a systematic review and meta-analysis.

Sci Rep 2016 Jan 22;6:19718. Epub 2016 Jan 22.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726375PMC
January 2016

Diabetes mellitus and risk of age-related macular degeneration: a systematic review and meta-analysis.

PLoS One 2014 19;9(9):e108196. Epub 2014 Sep 19.

Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University and State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.

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November 2015

Effects of EGCG content in green tea extract on pharmacokinetics, oxidative status and expression of inflammatory and apoptotic genes in the rat ocular tissues.

J Nutr Biochem 2015 Nov 26;26(11):1357-67. Epub 2015 Jul 26.

Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong. Electronic address:

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November 2015

Transdifferentiation of periodontal ligament-derived stem cells into retinal ganglion-like cells and its microRNA signature.

Sci Rep 2015 Nov 9;5:16429. Epub 2015 Nov 9.

Department of Ophthalmology &Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

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November 2015

Genetic Associations of Interleukin-related Genes with Graves' Ophthalmopathy: a Systematic Review and Meta-analysis.

Sci Rep 2015 Nov 18;5:16672. Epub 2015 Nov 18.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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November 2015

SPP2 Mutations Cause Autosomal Dominant Retinitis Pigmentosa.

Sci Rep 2015 Oct 13;5:14867. Epub 2015 Oct 13.

Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University and State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.

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October 2015

Association of Genetic Variants with Polypoidal Choroidal Vasculopathy: A Systematic Review and Updated Meta-analysis.

Ophthalmology 2015 Sep 13;122(9):1854-65. Epub 2015 Jun 13.

Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China; Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2015.05.012DOI Listing
September 2015

A common variant near TGFBR3 is associated with primary open angle glaucoma.

Authors:
Zheng Li R Rand Allingham Masakazu Nakano Liyun Jia Yuhong Chen Yoko Ikeda Baskaran Mani Li-Jia Chen Changwon Kee David F Garway-Heath Sarangapani Sripriya Nobuo Fuse Khaled K Abu-Amero Chukai Huang Prasanthi Namburi Kathryn Burdon Shamira A Perera Puya Gharahkhani Ying Lin Morio Ueno Mineo Ozaki Takanori Mizoguchi Subbiah Ramasamy Krishnadas Essam A Osman Mei Chin Lee Anita S Y Chan Liza-Sharmini A Tajudin Tan Do Aurelien Goncalves Pascal Reynier Hong Zhang Rupert Bourne David Goh David Broadway Rahat Husain Anil K Negi Daniel H Su Ching-Lin Ho Augusto Azuara Blanco Christopher K S Leung Tina T Wong Azhany Yakub Yutao Liu Monisha E Nongpiur Jong Chul Han Do Nhu Hon Balekudaru Shantha Bowen Zhao Jinghong Sang NiHong Zhang Ryuichi Sato Kengo Yoshii Songhomita Panda-Jonas Allison E Ashley Koch Leon W Herndon Sayoko E Moroi Pratap Challa Jia Nee Foo Jin-Xin Bei Yi-Xin Zeng Cameron P Simmons Tran Nguyen Bich Chau Philomenadin Ferdinamarie Sharmila Merwyn Chew Blanche Lim Pansy O S Tam Elaine Chua Xiao Yu Ng Victor H K Yong Yaan Fun Chong Wee Yang Meah Saravanan Vijayan Sohn Seongsoo Wang Xu Yik Ying Teo Jessica N Cooke Bailey Jae H Kang Jonathan L Haines Ching Yu Cheng Seang-Mei Saw E-Shyong Tai Julia E Richards Robert Ritch Douglas E Gaasterland Louis R Pasquale Jianjun Liu Jost B Jonas Dan Milea Ronnie George Saleh A Al-Obeidan Kazuhiko Mori Stuart Macgregor Alex W Hewitt Christopher A Girkin Mingzhi Zhang Periasamy Sundaresan Lingam Vijaya David A Mackey Tien Yin Wong Jamie E Craig Xinghuai Sun Shigeru Kinoshita Janey L Wiggs Chiea-Chuen Khor Zhenglin Yang Chi Pui Pang Ningli Wang Michael A Hauser Kei Tashiro Tin Aung Eranga N Vithana

Hum Mol Genet 2015 Jul 10;24(13):3880-92. Epub 2015 Apr 10.

Singapore Eye Research Institute, Department of Ophthalmology, Yong Loo Lin School of Medicine, Duke-NUS Graduate Medical School, Singapore, Singapore,

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July 2015

Association of common variants in TCF4 and PTPRG with Fuchs' corneal dystrophy: a systematic review and meta-analysis.

PLoS One 2014 9;9(10):e109142. Epub 2014 Oct 9.

Department of Ophthalmology and Visual Sciences, Prince of Wales hospital, Hong Kong, China; Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192317PMC
June 2015

Signature microRNAs in human cornea limbal epithelium.

Funct Integr Genomics 2015 May 7;15(3):277-94. Epub 2014 Dec 7.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Sha Tin, Hong Kong, China.

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May 2015

Genotype-phenotype correlation and mutation spectrum in a large cohort of patients with inherited retinal dystrophy revealed by next-generation sequencing.

Genet Med 2015 Apr 6;17(4):271-8. Epub 2014 Nov 6.

The Eye Hospital of Wenzhou Medical University, State Key Laboratory Cultivation Base and Key Laboratory of Vision Science, Ministry of Health, Wenzhou, China.

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http://dx.doi.org/10.1038/gim.2014.138DOI Listing
April 2015

Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations.

Nat Commun 2015 Apr 15;6:6687. Epub 2015 Apr 15.

1] Key Laboratory of Vision Loss and Restoration, Ministry of Education of China, Beijing 100044, China [2] Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China [3] Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.

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http://dx.doi.org/10.1038/ncomms7687DOI Listing
April 2015

Ethnic differences in the association of SERPING1 with age-related macular degeneration and polypoidal choroidal vasculopathy.

Sci Rep 2015 Mar 24;5:9424. Epub 2015 Mar 24.

1] Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China [2] Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, the Chinese University of Hong Kong, Hong Kong, China.

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March 2015

Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians.

Nat Commun 2015 Mar 30;6:6817. Epub 2015 Mar 30.

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March 2015

Association of PEDF polymorphisms with age-related macular degeneration and polypoidal choroidal vasculopathy: a systematic review and meta-analysis.

Sci Rep 2015 Mar 30;5:9497. Epub 2015 Mar 30.

1] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, China [2] Department of Ophthalmology and Visual Sciences, Prince of Wales hospital, Hong Kong, China.

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March 2015

Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials.

Sci Rep 2015 Jan 16;5:7828. Epub 2015 Jan 16.

1] Geriatric Research, Education and Clinical Center, Miami Veterans Affairs Medical Center, Miami, FL, United States [2] Department of Biomedical Engineering, University of Miami, Coral Gables, FL, United States.

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January 2015

New loci and coding variants confer risk for age-related macular degeneration in East Asians.

Nat Commun 2015 Jan 28;6:6063. Epub 2015 Jan 28.

1] Singapore Eye Research Institute, Singapore 169856, Singapore [2] Division of Human Genetics, Genome Institute of Singapore, Singapore 138672, Singapore [3] Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117549, Singapore.

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January 2015

Determination of exogenous epigallocatechin gallate peracetate in mouse plasma using liquid chromatography with quadrupole time-of-flight mass spectrometry.

J Sep Sci 2014 Dec 18;37(23):3473-80. Epub 2014 Oct 18.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, Kowloon, Hong Kong; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.

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December 2014

Antagonist of GH-releasing hormone receptors alleviates experimental ocular inflammation.

Proc Natl Acad Sci U S A 2014 Dec 8;111(51):18303-8. Epub 2014 Dec 8.

Department of Ophthalmology & Visual Sciences and Joint Shantou International Eye Center, Shantou University and The Chinese University of Hong Kong, 515041 Shantou, China;

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December 2014

Gender specific association of a complement component 3 polymorphism with polypoidal choroidal vasculopathy.

Sci Rep 2014 Nov 12;4:7018. Epub 2014 Nov 12.

1] Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China [2] Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong, China.

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November 2014

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma.

Nat Genet 2014 Oct 31;46(10):1115-9. Epub 2014 Aug 31.

1] Sichuan Provincial Key Laboratory for Human Disease Gene Study, Hospital of the University of Electronic Science and Technology of China and Sichuan Provincial People's Hospital, Chengdu, China. [2] School of Medicine, University of Electronic Science and Technology of China, Chengdu, China. [3] Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, China. [4].

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October 2014

Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3.

Nat Genet 2014 Sep 10;46(9):1007-11. Epub 2014 Aug 10.

1] The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. [2] Chongqing Key Laboratory of Ophthalmology, Chongqing, China. [3] Chongqing Eye Institute, Chongqing, China. [4].

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September 2014