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Publications Authored by Chi C Wong | PubFacts
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26Publications

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Mechanism of eIF6 release from the nascent 60S ribosomal subunit.

Nat Struct Mol Biol 2015 Nov 19;22(11):914-9. Epub 2015 Oct 19.

Cambridge Institute for Medical Research, Cambridge, UK.

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http://dx.doi.org/10.1038/nsmb.3112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871238PMC
November 2015

The utility of transposon mutagenesis for cancer studies in the era of genome editing.

Genome Biol 2015 Oct 19;16:229. Epub 2015 Oct 19.

Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1HH, UK.

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http://dx.doi.org/10.1186/s13059-015-0794-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612416PMC
October 2015

Phospho-aspirin-2 (MDC-22) inhibits estrogen receptor positive breast cancer growth both in vitro and in vivo by a redox-dependent effect.

PLoS One 2014 4;9(11):e111720. Epub 2014 Nov 4.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, New York, United States of America; Medicon Pharmaceuticals, Inc, Setauket, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111720PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219766PMC
June 2015

Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: implications for their clinical pharmacology.

Pharm Res 2015 May 13;32(5):1663-75. Epub 2014 Nov 13.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, HSC, T-17 Room 080, Stony Brook, NY, 11794-8173, USA.

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http://dx.doi.org/10.1007/s11095-014-1565-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382427PMC
May 2015

A novel ibuprofen derivative with anti-lung cancer properties: synthesis, formulation, pharmacokinetic and efficacy studies.

Int J Pharm 2014 Dec 11;477(1-2):236-43. Epub 2014 Oct 11.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2014.10.019DOI Listing
December 2014

Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen.

J Pharmacol Exp Ther 2014 Oct 21;351(1):61-6. Epub 2014 Jul 21.

Department of Medicine, Stony Brook University, Stony Brook, New York (G.M., C.C.W., Y.S., C.A.A., R.R., B.R.); and Medicon Pharmaceuticals, Inc. (P.P.C., B.R.), Stony Brook, New York

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http://dx.doi.org/10.1124/jpet.114.217208DOI Listing
October 2014

Therapy for mitochondrial genetic disease: are we at the thin end of the wedge?

Reprod Biomed Online 2014 Aug;29(2):147-9

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http://dx.doi.org/10.1016/j.rbmo.2014.06.003DOI Listing
August 2014

Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate.

Int J Oncol 2014 Feb 27;44(2):521-9. Epub 2013 Nov 27.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY 11794-8173, USA.

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http://dx.doi.org/10.3892/ijo.2013.2190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898803PMC
February 2014

Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics.

Int J Oncol 2013 Sep 27;43(3):895-902. Epub 2013 Jun 27.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY 11794-8173, USA.

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http://dx.doi.org/10.3892/ijo.2013.1995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787887PMC
September 2013

Aerosol administration of phospho-sulindac inhibits lung tumorigenesis.

Mol Cancer Ther 2013 Aug 3;12(8):1417-28. Epub 2013 May 3.

Division of Cancer Prevention, Stony Brook University, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0006-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3780561PMC
August 2013

The anticancer effect of phospho-tyrosol-indomethacin (MPI-621), a novel phosphoderivative of indomethacin: in vitro and in vivo studies.

Carcinogenesis 2013 Apr 21;34(4):943-51. Epub 2013 Jan 21.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY 11794-8175, USA.

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http://dx.doi.org/10.1093/carcin/bgs394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616666PMC
April 2013

Comparative in vitro metabolism of phospho-tyrosol-indomethacin by mice, rats and humans.

Biochem Pharmacol 2013 Apr 8;85(8):1195-202. Epub 2013 Feb 8.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, HSC, T17-080, Stony Brook, NY 11794, USA.

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http://dx.doi.org/10.1016/j.bcp.2013.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604040PMC
April 2013

In vitro and in vivo metabolic studies of phospho-aspirin (MDC-22).

Pharm Res 2012 Dec 11;29(12):3292-301. Epub 2012 Jul 11.

Stony Brook University, Division of Cancer Prevention, HSC, T17-080, Stony Brook, New York 11794-8175, USA.

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http://dx.doi.org/10.1007/s11095-012-0821-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602912PMC
December 2012

Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer.

Int J Oncol 2012 Oct 27;41(4):1199-203. Epub 2012 Jul 27.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, NY, USA.

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http://dx.doi.org/10.3892/ijo.2012.1577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583614PMC
October 2012

Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.

J Pharmacol Exp Ther 2012 Feb 15;340(2):422-32. Epub 2011 Nov 15.

Division of Cancer Prevention, Department of Medicine, Stony Brook University, Stony Brook, New York 11794-8173, USA.

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http://dx.doi.org/10.1124/jpet.111.188508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263964PMC
February 2012

Defective ribosome assembly in Shwachman-Diamond syndrome.

Blood 2011 Oct 29;118(16):4305-12. Epub 2011 Jul 29.

Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom.

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http://www.bloodjournal.org/content/early/2011/07/28/blood-2
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-06-35
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http://dx.doi.org/10.1182/blood-2011-06-353938DOI Listing
October 2011

Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters.

Mol Nutr Food Res 2011 Jul 29;55(7):979-88. Epub 2011 Apr 29.

School of Food Science and Nutrition, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1002/mnfr.201000652DOI Listing
July 2011

Clinical features and outcomes of Fusarium keratitis associated with contact lens wear.

Eye Contact Lens 2008 Mar;34(2):113-6

Department of Ophthalmology, Queen Mary Hospital, Hong Kong, China.

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http://dx.doi.org/10.1097/ICL.0b013e318145108cDOI Listing
March 2008

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast.

Nat Genet 2007 Apr 11;39(4):486-95. Epub 2007 Mar 11.

Medical Research Council (MRC) Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://dx.doi.org/10.1038/ng1994DOI Listing
April 2007

Hydroxyurea-induced pneumonitis in a patient with chronic idiopathic myelofibrosis after prolonged drug exposure.

Eur J Haematol 2003 Nov;71(5):388-90

Department of Haematology, The Whittington Hospital, London, UK.

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http://dx.doi.org/10.1034/j.1600-0609.2003.00123.xDOI Listing
November 2003