Chester Kuei

Chester Kuei

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Chester Kuei

Chester Kuei

Publications by authors named "Chester Kuei"

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Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability.

Bioorg Med Chem Lett 2016 10 12;26(20):4888-4891. Epub 2016 Sep 12.

Janssen Research & Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.09.029DOI Listing
October 2016

Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with Antilipolytic Effects.

ACS Med Chem Lett 2012 Aug 11;3(8):637-9. Epub 2012 Jun 11.

Janssen Research & Development, LLC , San Diego, California 92121, United States.

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http://dx.doi.org/10.1021/ml3000676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025785PMC
August 2012

Study of GPR81, the lactate receptor, from distant species identifies residues and motifs critical for GPR81 functions.

Mol Pharmacol 2011 Nov 23;80(5):848-58. Epub 2011 Aug 23.

Johnson and Johnson Pharmaceutical Research and Development, San Diego, CA 92121, USA.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.111.07
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http://dx.doi.org/10.1124/mol.111.074500DOI Listing
November 2011

Oxysterols direct B-cell migration through EBI2.

Nature 2011 Jul 27;475(7357):519-23. Epub 2011 Jul 27.

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, California 92121, USA.

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http://dx.doi.org/10.1038/nature10226DOI Listing
July 2011

Modulation of hippocampal theta oscillations and spatial memory by relaxin-3 neurons of the nucleus incertus.

Learn Mem 2009 Nov 30;16(11):730-42. Epub 2009 Oct 30.

Howard Florey Institute, The University of Melbourne, Victoria 3010, Australia.

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http://dx.doi.org/10.1101/lm.1438109DOI Listing
November 2009

Metabolic and neuroendocrine responses to RXFP3 modulation in the central nervous system.

Ann N Y Acad Sci 2009 Apr;1160:242-9

Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California 92121, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2008.03812.xDOI Listing
April 2009

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.

J Biol Chem 2009 Jan 1;284(5):2811-22. Epub 2008 Dec 1.

Johnson & Johnson Pharmaceutical Research & Development LLC, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1074/jbc.M806409200DOI Listing
January 2009

Identification of the domains in RXFP4 (GPCR142) responsible for the high affinity binding and agonistic activity of INSL5 at RXFP4 compared to RXFP3 (GPCR135).

Eur J Pharmacol 2008 Aug 27;590(1-3):43-52. Epub 2008 May 27.

Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.ejphar.2008.05.025DOI Listing
August 2008

G-protein-coupled receptor (GPCR)-142 does not contribute to relaxin-3 binding in the mouse brain: further support that relaxin-3 is the physiological ligand for GPCR135.

Neuroendocrinology 2005 13;82(3-4):139-50. Epub 2006 Jan 13.

Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1159/000091267DOI Listing
June 2006

A novel form of neurotensin post-translationally modified by arginylation.

J Biol Chem 2005 Oct 8;280(42):35089-97. Epub 2005 Aug 8.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1074/jbc.M502567200DOI Listing
October 2005

Identification and pharmacological characterization of prokineticin 2 beta as a selective ligand for prokineticin receptor 1.

Mol Pharmacol 2005 Jun 16;67(6):2070-6. Epub 2005 Mar 16.

Pharmaceutical Research and Development, Johnson & Johnson LLC, 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1124/mol.105.011619DOI Listing
June 2005

Recent progress in relaxin-3-related research.

Ann N Y Acad Sci 2005 May;1041:47-60

Johnson & Johnson Pharmaceutical Research and Development, LLC, San Diego, CA 92121.

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http://dx.doi.org/10.1196/annals.1282.009DOI Listing
May 2005

Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing.

Neuroendocrinology 2004 26;80(5):298-307. Epub 2005 Jan 26.

Neuroscience Group, Johnson & Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1159/000083656DOI Listing
April 2005

Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog.

Eur J Pharmacol 2005 Apr 20;513(3):181-92. Epub 2005 Apr 20.

Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.ejphar.2005.03.013DOI Listing
April 2005

Pharmacological characterization of relaxin-3/INSL7 receptors GPCR135 and GPCR142 from different mammalian species.

J Pharmacol Exp Ther 2005 Jan 14;312(1):83-95. Epub 2004 Sep 14.

Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1124/jpet.104.073486DOI Listing
January 2005

INSL5 is a high affinity specific agonist for GPCR142 (GPR100).

J Biol Chem 2005 Jan 2;280(1):292-300. Epub 2004 Nov 2.

Johnson & Johnson Pharmaceutical Research and Development, San Diego, California 92121, USA.

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http://dx.doi.org/10.1074/jbc.M409916200DOI Listing
January 2005

Identification of relaxin-3/INSL7 as a ligand for GPCR142.

J Biol Chem 2003 Dec 30;278(50):50765-70. Epub 2003 Sep 30.

Johnson & Johnson Pharmaceutical Research and Development, L.L.C., San Diego, California 92121, USA.

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http://www.jbc.org/content/278/50/50765.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M308996200
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http://dx.doi.org/10.1074/jbc.M308996200DOI Listing
December 2003

Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.

J Biol Chem 2003 Dec 30;278(50):50754-64. Epub 2003 Sep 30.

Johnson & Johnson Pharmaceutical Research and Development, L.L.C., San Diego, California 92121, USA.

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http://dx.doi.org/10.1074/jbc.M308995200DOI Listing
December 2003

Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.

J Neurosci 2003 Feb;23(4):1169-78

Neuroscience, Johnson & Johnson Pharmaceutical Research and Development, San Diego, California 92121, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742242PMC
February 2003