Publications by authors named "Cheryl A Keller"

33Publications

Alteration of genome folding via contact domain boundary insertion.

Nat Genet 2020 Aug 31. Epub 2020 Aug 31.

Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/s41588-020-0680-8DOI Listing
August 2020

S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data.

Nucleic Acids Res 2020 05;48(8):e43

Dept. of Biochemistry and Molecular Biology, The Pennsylvania State University, Wartik Laboratory, University Park, PA 16802, USA.

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http://dx.doi.org/10.1093/nar/gkaa105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192629PMC
May 2020

Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription.

Cell Rep 2019 04;27(2):400-415.e5

Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.03.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664437PMC
April 2019

Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation.

Mol Cell 2019 02 13;73(3):519-532.e4. Epub 2018 Dec 13.

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368450PMC
February 2019

The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.

Mol Cell 2017 Apr;66(1):102-116.e7

Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393350PMC
April 2017

A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition.

Genes Dev 2016 06;30(12):1423-39

Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1101/gad.280859.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926865PMC
June 2016

SBR-Blood: systems biology repository for hematopoietic cells.

Nucleic Acids Res 2016 Jan 20;44(D1):D925-31. Epub 2015 Nov 20.

National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/nar/gkv1263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702891PMC
January 2016

Genome-Wide Organization of GATA1 and TAL1 Determined at High Resolution.

Mol Cell Biol 2016 Jan 26;36(1):157-72. Epub 2015 Oct 26.

Center for Eukaryotic Gene Regulation, Center for Comparative Genomics and Bioinformatics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA

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http://dx.doi.org/10.1128/MCB.00806-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702602PMC
January 2016

Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility.

Epigenetics Chromatin 2015 23;8:16. Epub 2015 Apr 23.

Center for Comparative Genomics and Bioinformatics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, 304 Wartik Laboratory, University Park, PA 16802 USA.

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http://dx.doi.org/10.1186/s13072-015-0009-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432502PMC
May 2015

Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system.

Genom Data 2015 Jun;4:1-7

Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, Pennsylvania 16802, USA ; Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22135960150001
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http://dx.doi.org/10.1016/j.gdata.2015.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338950PMC
June 2015

Functions of BET proteins in erythroid gene expression.

Blood 2015 Apr 18;125(18):2825-34. Epub 2015 Feb 18.

Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA; Perelman School of Medicine, University of Pennsylvania, Philadelphia PA; and.

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http://dx.doi.org/10.1182/blood-2014-10-607309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424630PMC
April 2015

A comparative encyclopedia of DNA elements in the mouse genome.

Authors:
Feng Yue Yong Cheng Alessandra Breschi Jeff Vierstra Weisheng Wu Tyrone Ryba Richard Sandstrom Zhihai Ma Carrie Davis Benjamin D Pope Yin Shen Dmitri D Pervouchine Sarah Djebali Robert E Thurman Rajinder Kaul Eric Rynes Anthony Kirilusha Georgi K Marinov Brian A Williams Diane Trout Henry Amrhein Katherine Fisher-Aylor Igor Antoshechkin Gilberto DeSalvo Lei-Hoon See Meagan Fastuca Jorg Drenkow Chris Zaleski Alex Dobin Pablo Prieto Julien Lagarde Giovanni Bussotti Andrea Tanzer Olgert Denas Kanwei Li M A Bender Miaohua Zhang Rachel Byron Mark T Groudine David McCleary Long Pham Zhen Ye Samantha Kuan Lee Edsall Yi-Chieh Wu Matthew D Rasmussen Mukul S Bansal Manolis Kellis Cheryl A Keller Christapher S Morrissey Tejaswini Mishra Deepti Jain Nergiz Dogan Robert S Harris Philip Cayting Trupti Kawli Alan P Boyle Ghia Euskirchen Anshul Kundaje Shin Lin Yiing Lin Camden Jansen Venkat S Malladi Melissa S Cline Drew T Erickson Vanessa M Kirkup Katrina Learned Cricket A Sloan Kate R Rosenbloom Beatriz Lacerda de Sousa Kathryn Beal Miguel Pignatelli Paul Flicek Jin Lian Tamer Kahveci Dongwon Lee W James Kent Miguel Ramalho Santos Javier Herrero Cedric Notredame Audra Johnson Shinny Vong Kristen Lee Daniel Bates Fidencio Neri Morgan Diegel Theresa Canfield Peter J Sabo Matthew S Wilken Thomas A Reh Erika Giste Anthony Shafer Tanya Kutyavin Eric Haugen Douglas Dunn Alex P Reynolds Shane Neph Richard Humbert R Scott Hansen Marella De Bruijn Licia Selleri Alexander Rudensky Steven Josefowicz Robert Samstein Evan E Eichler Stuart H Orkin Dana Levasseur Thalia Papayannopoulou Kai-Hsin Chang Arthur Skoultchi Srikanta Gosh Christine Disteche Piper Treuting Yanli Wang Mitchell J Weiss Gerd A Blobel Xiaoyi Cao Sheng Zhong Ting Wang Peter J Good Rebecca F Lowdon Leslie B Adams Xiao-Qiao Zhou Michael J Pazin Elise A Feingold Barbara Wold James Taylor Ali Mortazavi Sherman M Weissman John A Stamatoyannopoulos Michael P Snyder Roderic Guigo Thomas R Gingeras David M Gilbert Ross C Hardison Michael A Beer Bing Ren

Nature 2014 Nov;515(7527):355-64

Ludwig Institute for Cancer Research and University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/nature13992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266106PMC
November 2014

Dynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.

Genome Res 2014 Dec 15;24(12):1945-62. Epub 2014 Oct 15.

Center for Comparative Genomics and Bioinformatics, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA;

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http://dx.doi.org/10.1101/gr.164830.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248312PMC
December 2014

An encyclopedia of mouse DNA elements (Mouse ENCODE).

August 2012

Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

Pharmacol Ther 2004 Jun;102(3):195-221

Department of Biology, Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1016/j.pharmthera.2004.04.003DOI Listing
June 2004

The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ.

J Neurosci 2004 Jun;24(26):5881-91

Department of Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1037-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366890PMC
June 2004