Chengyu Liu

Chengyu Liu

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Chimeric Mouse Generation by ES Cell Blastocyst Microinjection and Uterine Transfer.

Methods Mol Biol 2019 ;1874:99-114

Transgenic Core Facility, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://link.springer.com/10.1007/978-1-4939-8831-0_6
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http://dx.doi.org/10.1007/978-1-4939-8831-0_6DOI Listing
June 2019

Using CRISPR/Cas9 for Gene Knockout in Immunodeficient NSG Mice.

Methods Mol Biol 2019 ;1874:139-168

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://link.springer.com/10.1007/978-1-4939-8831-0_8
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http://dx.doi.org/10.1007/978-1-4939-8831-0_8DOI Listing
June 2019

Generation of Conditional Knockout Mice by Sequential Insertion of Two loxP Sites In Cis Using CRISPR/Cas9 and Single-Stranded DNA Oligonucleotides.

Methods Mol Biol 2019 ;1874:191-210

Transgenic Core Facility, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://link.springer.com/10.1007/978-1-4939-8831-0_11
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http://dx.doi.org/10.1007/978-1-4939-8831-0_11DOI Listing
June 2019

Adipose Lipocalin 2 overexpression protects against age-related decline in thermogenic function of adipose tissue and metabolic deterioration.

Mol Metab 2019 Jun 20;24:18-29. Epub 2019 Mar 20.

Department of Food Science and Nutrition, University of Minnesota, Twin Cities, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531839PMC
June 2019

Ventricular ectopic beat detection using a wavelet transform and a convolutional neural network.

Physiol Meas 2019 Jun 4;40(5):055002. Epub 2019 Jun 4.

Department of Engineering Science, University of Oxford, Oxford, United Kingdom. Department of Biomedical Informatics, Emory University, Atlanta, GA, United States of America.

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http://dx.doi.org/10.1088/1361-6579/ab17f0DOI Listing
June 2019

PerPAS: Topology-Based Single Sample Pathway Analysis Method.

IEEE/ACM Trans Comput Biol Bioinform 2018 May-Jun;15(3):1022-1027. Epub 2017 Mar 8.

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http://dx.doi.org/10.1109/TCBB.2017.2679745DOI Listing
May 2019

Development of Novel Hearing Aids by Using Image Recognition Technology.

IEEE J Biomed Health Inform 2019 May 15;23(3):1163-1170. Epub 2018 May 15.

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http://dx.doi.org/10.1109/JBHI.2018.2836180DOI Listing
May 2019

Electrochemical [4+2] Annulation-Rearrangement-Aromatization of Styrenes: Synthesis of Naphthalene Derivatives.

Angew Chem Int Ed Engl 2019 May 8;58(20):6756-6760. Epub 2019 Apr 8.

Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China.

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http://dx.doi.org/10.1002/anie.201902315DOI Listing
May 2019

An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene.

Stem Cell Res 2019 May 23;37:101427. Epub 2019 Mar 23.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559735PMC
May 2019

Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene.

Stem Cell Res 2019 May 12;37:101436. Epub 2019 Apr 12.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101436DOI Listing
May 2019

A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p.R854X mutation in the GAA gene.

Stem Cell Res 2019 May 11;37:101435. Epub 2019 Apr 11.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101435DOI Listing
May 2019

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription.

Nat Commun 2019 05 6;10(1):2071. Epub 2019 May 6.

Cancer and Stem Cell Epigenetics Section, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-019-10102-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502810PMC
May 2019

Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene.

Stem Cell Res 2019 May 25;37:101451. Epub 2019 Apr 25.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101451DOI Listing
May 2019

A Single Hydrogen to Fluorine Substitution Reverses the Trend of Surface Composition Enrichment of Sorafenib Amorphous Solid Dispersion upon Moisture Exposure.

Pharm Res 2019 May 17;36(7):105. Epub 2019 May 17.

School of Pharmaceutical Sciences, Beijing Advanced Innovation Center for Structural Biology, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Tsinghua University, Beijing, 100084, People's Republic of China.

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http://dx.doi.org/10.1007/s11095-019-2632-5DOI Listing
May 2019

An induced pluripotent stem cell line (TRNDi009-C) from a Niemann-Pick disease type A patient carrying a heterozygous p.L302P (c.905 T>C) mutation in the SMPD1 gene.

Stem Cell Res 2019 May 15;38:101461. Epub 2019 May 15.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101461DOI Listing
May 2019

Generation of an induced pluripotent stem cell line (TRNDi005-A) from a Mucopolysaccharidosis Type IVA (MPS IVA) patient carrying compound heterozygous p.R61W and p.WT405del mutations in the GALNS gene.

Stem Cell Res 2019 Apr 15;36:101408. Epub 2019 Feb 15.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2019.101408DOI Listing
April 2019

Advances in minimally invasive surgery and clinical measurement.

Comput Assist Surg (Abingdon) 2019 Apr 2:1-4. Epub 2019 Apr 2.

b Central Taiwan University of Science and Technology , Takun , Taiwan.

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http://dx.doi.org/10.1080/24699322.2018.1560103DOI Listing
April 2019

Heart rate variability monitoring for emotion and disorders of emotion.

Physiol Meas 2019 Apr 11. Epub 2019 Apr 11.

School of Instrument Science and Engineering, Southeast University, Sipailou 2, Nanjing, Jiangsu, 210096, CHINA.

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http://dx.doi.org/10.1088/1361-6579/ab1887DOI Listing
April 2019

An Improved Sliding Window Area Method for Wave Detection.

Comput Math Methods Med 2019 1;2019:3130527. Epub 2019 Apr 1.

School of Instrument Science and Engineering, Southeast University, Nanjing 210096, China.

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http://dx.doi.org/10.1155/2019/3130527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466942PMC
April 2019

Histone demethylase UTX is a therapeutic target for diabetic kidney disease.

J Physiol 2019 Mar 25;597(6):1643-1660. Epub 2018 Dec 25.

Tongji School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://doi.wiley.com/10.1113/JP277367
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http://dx.doi.org/10.1113/JP277367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418754PMC
March 2019

Duck viral infection escalated the incidence of avian pathogenic Escherichia coli in China.

Transbound Emerg Dis 2019 Mar 9;66(2):929-938. Epub 2019 Jan 9.

College of Veterinary Medicine, Shandong Agricultural University, Shandong, China.

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http://dx.doi.org/10.1111/tbed.13107DOI Listing
March 2019

Cardiorespiratory Coupling Analysis Based on Entropy and Cross-Entropy in Distinguishing Different Depression Stages.

Front Physiol 2019 29;10:359. Epub 2019 Mar 29.

School of Instrument Science and Engineering, Southeast University, Nanjing, China.

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http://dx.doi.org/10.3389/fphys.2019.00359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449862PMC
March 2019

Short-term QT interval variability in patients with coronary artery disease and congestive heart failure: a comparison with healthy control subjects.

Med Biol Eng Comput 2019 Feb 25;57(2):389-400. Epub 2018 Aug 25.

School of Instrument Science and Engineering, Southeast University, Nanjing, People's Republic of China.

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http://link.springer.com/10.1007/s11517-018-1870-8
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http://dx.doi.org/10.1007/s11517-018-1870-8DOI Listing
February 2019

Macrophage fatty acid oxidation inhibits atherosclerosis progression.

J Mol Cell Cardiol 2019 Feb 9;127:270-276. Epub 2019 Jan 9.

Center for Molecular Medicine, NIH, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA; Aging Institute, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.01.003DOI Listing
February 2019

Simultaneous targeting of linked loci in mouse embryos using base editing.

Sci Rep 2019 Feb 7;9(1):1662. Epub 2019 Feb 7.

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland, 20892, USA.

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http://www.nature.com/articles/s41598-018-33533-5
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http://dx.doi.org/10.1038/s41598-018-33533-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367434PMC
February 2019

PCG Classification Using Multidomain Features and SVM Classifier.

Biomed Res Int 2018 9;2018:4205027. Epub 2018 Jul 9.

School of Instrument Science and Engineering, Southeast University, Nanjing, China.

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http://dx.doi.org/10.1155/2018/4205027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077676PMC
January 2019

H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development.

Nucleic Acids Res 2019 Jan;47(2):607-620

Adipocyte Biology and Gene Regulation Section, Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/nar/gky982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344897PMC
January 2019

Impact of a Single Hydrogen Substitution by Fluorine on the Molecular Interaction and Miscibility between Sorafenib and Polymers.

Mol Pharm 2019 01 13;16(1):318-326. Epub 2018 Dec 13.

School of Pharmaceutical Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education) , Tsinghua University , Beijing 100084 , China.

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http://pubs.acs.org/doi/10.1021/acs.molpharmaceut.8b00970
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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00970DOI Listing
January 2019

Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene.

Stem Cell Res 2019 01 26;34:101374. Epub 2018 Dec 26.

National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.101374DOI Listing
January 2019

Deep learning in the cross-time frequency domain for sleep staging from a single-lead electrocardiogram.

Physiol Meas 2018 12 21;39(12):124005. Epub 2018 Dec 21.

Department of Biomedical Informatics, Emory University, Atlanta, GA, United States of America.

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http://stacks.iop.org/0967-3334/39/i=12/a=124005?key=crossre
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http://dx.doi.org/10.1088/1361-6579/aaf339DOI Listing
December 2018

Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation.

Nucleic Acids Res 2018 11;46(20):10796-10809

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237736PMC
November 2018

Targeting fidelity of adenine and cytosine base editors in mouse embryos.

Nat Commun 2018 11 15;9(1):4804. Epub 2018 Nov 15.

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, 20892, USA.

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http://www.nature.com/articles/s41467-018-07322-7
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http://dx.doi.org/10.1038/s41467-018-07322-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238002PMC
November 2018

Efficient sleep classification based on entropy features and a support vector machine classifier.

Physiol Meas 2018 11 26;39(11):115005. Epub 2018 Nov 26.

School of Control Science and Engineering, Shandong University, Jinan, People's Republic of China. School of Information Technology and Electrical Engineering, University of Queensland, Queensland, Australia.

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http://stacks.iop.org/0967-3334/39/i=11/a=115005?key=crossre
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http://dx.doi.org/10.1088/1361-6579/aae943DOI Listing
November 2018

Identification of Homologous Recombination Events in Mouse Embryonic Stem Cells Using Southern Blotting and Polymerase Chain Reaction.

J Vis Exp 2018 11 20(141). Epub 2018 Nov 20.

Lab of Animal Models and Functional Genomics (LAMFG), The Key Laboratory of Animal Vaccine & Protein Engineering, College of Veterinary Medicine, Hunan Agricultural University (HUNAU);

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http://dx.doi.org/10.3791/58467DOI Listing
November 2018

Effects of Apelin Peptides on Diabetic Complications.

Curr Protein Pept Sci 2018 ;19(2):179-189

Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.

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http://dx.doi.org/10.2174/1389203718666170918154728DOI Listing
October 2018

Changes in the bilateral pulse transit time difference with a moving arm.

Technol Health Care 2018 ;26(S1):113-119

School of Instrument Science and Engineering, Southeast University, Nanjing 210096, Jiangsu, China.

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http://dx.doi.org/10.3233/THC-174256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005010PMC
October 2018

Aggregation of Hydroxypropyl Methylcellulose Acetate Succinate under Its Dissolving pH and the Impact on Drug Supersaturation.

Mol Pharm 2018 10 28;15(10):4643-4653. Epub 2018 Aug 28.

School of Pharmaceutical Sciences, and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education) , Tsinghua University , Beijing , China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00633DOI Listing
October 2018

An open source benchmarked toolbox for cardiovascular waveform and interval analysis.

Physiol Meas 2018 10 11;39(10):105004. Epub 2018 Oct 11.

Department of Biomedical Informatics, Emory University School of Medicine, Woodruff Memorial Research Bldg, Suite 4100, 101 Woodruff Circle, Atlanta, GA 30322, United States of America. Department of Epidemiology, Rollins School of Public Health at Emory University, 1518 Clifton Road NE, Room 3053, Atlanta, GA 30322, United States of America.

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http://iopscience.iop.org/article/10.1088/1361-6579/aae021
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http://dx.doi.org/10.1088/1361-6579/aae021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442742PMC
October 2018

Mutation frequency is not increased in CRISPR-Cas9-edited mice.

Nat Methods 2018 10;15(10):756-758

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, USA.

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http://www.nature.com/articles/s41592-018-0148-2
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http://dx.doi.org/10.1038/s41592-018-0148-2DOI Listing
October 2018

Lipocalin 2 regulates retinoic acid-induced activation of beige adipocytes

J Mol Endocrinol 2018 Oct 1;61(3):115-126. Epub 2018 Oct 1.

Department of Food Science and Nutrition, University of Minnesota, Twin Cities, Minnesota, USA

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https://jme.bioscientifica.com/view/journals/jme/61/3/JME-18
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http://dx.doi.org/10.1530/JME-18-0017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445544PMC
October 2018

Oxidation of Methionine 77 in Calmodulin Alters Mouse Growth and Behavior.

Antioxidants (Basel) 2018 Oct 13;7(10). Epub 2018 Oct 13.

Laboratory of Biochemistry, National Heart, Lung, and Blood Institute; Bethesda, MD 20892-8012, USA.

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http://www.mdpi.com/2076-3921/7/10/140
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http://dx.doi.org/10.3390/antiox7100140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210676PMC
October 2018

Smart Wearables in Healthcare: Signal Processing, Device Development, and Clinical Applications.

J Healthc Eng 2018 9;2018:1696924. Epub 2018 Oct 9.

Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1155/2018/1696924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198576PMC
October 2018

A high-sensitivity HPLC-ELSD method for HPMC-AS quantification and its application in elucidating the release mechanism of HPMC-AS based amorphous solid dispersions.

Eur J Pharm Sci 2018 Sep 10;122:303-310. Epub 2018 Jul 10.

School of Pharmaceutical Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, and Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Tsinghua University, Beijing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09280987183030
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http://dx.doi.org/10.1016/j.ejps.2018.07.007DOI Listing
September 2018

Mouse Homolog of the Human R337H Mutation Reveals Its Role in Tumorigenesis.

Cancer Res 2018 Sep 24;78(18):5375-5383. Epub 2018 Jul 24.

Cardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-0016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139041PMC
September 2018

Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice.

Mol Biol Cell 2018 09 25;29(19):2326-2335. Epub 2018 Jul 25.

Laboratory of Molecular Cardiology, National Institutes of Health, Bethesda, MD 20892-1583.

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http://dx.doi.org/10.1091/mbc.E17-12-0713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249808PMC
September 2018

Benchmarking heart rate variability toolboxes.

J Electrocardiol 2017 Nov - Dec;50(6):744-747. Epub 2017 Aug 8.

Department of Biomedical Informatics, Emory University School of Medicine, Woodruff Memorial Research Bldg, Suite 4100, 101 Woodruff Circle, Atlanta, GA, United States; Department of Biomedical Engineering, Georgia Institute of Technology, 1760 Haygood Drive, HSRB Suite W200, Atlanta, GA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jelectrocard.2017.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696039PMC
August 2018

Necroptosis of tumor cells leads to tumor necrosis and promotes tumor metastasis.

Cell Res 2018 Aug 25;28(8):868-870. Epub 2018 Jun 25.

Center for Cancer Research, National Cancer Institute, National Institutes of Health, 37 Convent Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41422-018-0058-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082890PMC
August 2018

Schiff base interaction tuned mesoporous organosilica nanoplatforms with pH-responsive degradability for efficient anti-cancer drug delivery in vivo.

Chem Commun (Camb) 2018 Aug;54(66):9190-9193

Department of Chemistry, Key Lab of Organic Optoelectronics & Molecular Engineering, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1039/c8cc05043kDOI Listing
August 2018

Maintaining Supersaturation of Nimodipine by PVP with or without the Presence of Sodium Lauryl Sulfate and Sodium Taurocholate.

Mol Pharm 2018 07 30;15(7):2754-2763. Epub 2018 May 30.

School of Pharmaceutical Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, and MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology , Tsinghua University , Beijing 100084 , P.R. China.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00253DOI Listing
July 2018

A comparison of entropy approaches for AF discrimination.

Physiol Meas 2018 07 6;39(7):074002. Epub 2018 Jul 6.

The State Key Laboratory of Bioelectronics, Jiangsu Key Lab of Remote Measurement and Control, School of Instrument Science and Engineering, Southeast University, Nanjing, People's Republic of China. Department of Biomedical Informatics, Emory University, Atlanta, GA, United States of America.

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http://dx.doi.org/10.1088/1361-6579/aacc48DOI Listing
July 2018

3D bioprinting for cardiovascular regeneration and pharmacology.

Adv Drug Deliv Rev 2018 Jul 24;132:252-269. Epub 2018 Jul 24.

Department of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC 20052, USA; Department of Electrical and Computer Engineering, The George Washington University, Washington, DC 20052, USA; Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, USA; Department of Medicine, The George Washington University, Washington, DC 20052, USA. Electronic address:

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http://dx.doi.org/10.1016/j.addr.2018.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226324PMC
July 2018

Atrial Fibrillation Beat Identification Using the Combination of Modified Frequency Slice Wavelet Transform and Convolutional Neural Networks.

J Healthc Eng 2018 2;2018:2102918. Epub 2018 Jul 2.

The State Key Laboratory of Bioelectronics, Jiangsu Key Lab of Remote Measurement and Control, School of Instrument Science and Engineering, Southeast University, Nanjing 210096, China.

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http://dx.doi.org/10.1155/2018/2102918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051096PMC
July 2018

Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.

Nat Commun 2018 05 4;9(1):1796. Epub 2018 May 4.

Adipocyte Biology and Gene Regulation Section, LERB, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-04127-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935725PMC
May 2018

Performance Analysis of Ten Common QRS Detectors on Different ECG Application Cases.

J Healthc Eng 2018 8;2018:9050812. Epub 2018 May 8.

School of Control Science and Engineering, Shandong University, Jinan, China.

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http://dx.doi.org/10.1155/2018/9050812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964584PMC
May 2018

Identification and characterization of MYH9 locus for high efficient gene knock-in and stable expression in mouse embryonic stem cells.

PLoS One 2018 13;13(2):e0192641. Epub 2018 Feb 13.

Lab of Animal Models and Functional Genomics (LAMFG), The Key Laboratory of Animal Vaccine & Protein Engineering, College of Veterinary Medicine, Hunan Agricultural University (HUNAU), Changsha, Hunan, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192641PLOS
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April 2018

Screening and isolation of potential neuraminidase inhibitors from leaves of Ligustrum lucidum Ait. based on ultrafiltration, LC/MS, and online extraction-separation methods.

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Apr 6;1083:102-109. Epub 2018 Mar 6.

Central Laboratory, Changchun Normal University, No. 677 North Chang-ji Road, Changchun 130032, China.

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http://dx.doi.org/10.1016/j.jchromb.2018.03.006DOI Listing
April 2018

Oral bioavailability enhancement of β-lapachone, a poorly soluble fast crystallizer, by cocrystal, amorphous solid dispersion, and crystalline solid dispersion.

Eur J Pharm Biopharm 2018 Mar 2;124:73-81. Epub 2018 Jan 2.

School of Pharmaceutical Sciences and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University, Beijing 100084, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejpb.2017.12.016DOI Listing
March 2018

Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance.

J Pharm Sci 2018 01 26;107(1):317-326. Epub 2017 Oct 26.

School of Pharmaceutical Sciences and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.xphs.2017.10.028DOI Listing
January 2018

In vitro screening and isolation of human aromatase inhibitors from Cicer arietinum by a novel continuous online method combining chromatographic techniques.

J Sep Sci 2018 Jan 30;41(2):483-492. Epub 2017 Nov 30.

Central Laboratory, Changchun Normal University, Changchun, China.

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http://dx.doi.org/10.1002/jssc.201700990DOI Listing
January 2018

Relationship between carotid artery sclerosis and blood pressure variability in essential hypertension patients.

Comput Biol Med 2018 01 18;92:73-77. Epub 2017 Mar 18.

School of Instrument Science and Engineering, Southeast University, Nanjing 210018, China.

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http://dx.doi.org/10.1016/j.compbiomed.2017.03.012DOI Listing
January 2018

Dynamic visualization of multi-level molecular data: The Director package in R.

Comput Methods Programs Biomed 2018 Jan 12;153:129-136. Epub 2017 Oct 12.

Research Programs Unit, Genome-Scale Biology, Faculty of Medicine, University of Helsinki, Helsinki, POB 63, 00014, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.cmpb.2017.10.013DOI Listing
January 2018

Increased pulse wave transit time after percutaneous coronary intervention procedure in CAD patients.

Sci Rep 2018 01 8;8(1):115. Epub 2018 Jan 8.

Department of Cardiology, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, 250014, China.

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http://dx.doi.org/10.1038/s41598-017-18520-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758522PMC
January 2018

Hyperspectral Features of Oil-Polluted Sea Ice and the Response to the Contamination Area Fraction.

Sensors (Basel) 2018 Jan 15;18(1). Epub 2018 Jan 15.

Mullard Space Science Laboratory, Department of Space and Climate Physics, University College London, Holmbury St. Mary-Surrey RH5 6NT, UK.

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http://dx.doi.org/10.3390/s18010234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795472PMC
January 2018

Telomeric TERB1-TRF1 interaction is crucial for male meiosis.

Nat Struct Mol Biol 2017 Dec 30;24(12):1073-1080. Epub 2017 Oct 30.

Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1038/nsmb.3496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108177PMC
December 2017

Screening, separation, and evaluation of xanthine oxidase inhibitors from Paeonia lactiflora using chromatography combined with a multi-mode microplate reader.

J Sep Sci 2017 Nov 25;40(21):4160-4167. Epub 2017 Sep 25.

Clinical Department of Rehabilitation, College of Acupuncture and Massage, Changchun University of Chinese Medicine, Changchun, China.

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http://dx.doi.org/10.1002/jssc.201700690DOI Listing
November 2017

STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the gene locus.

Proc Natl Acad Sci U S A 2017 11 24;114(46):12111-12119. Epub 2017 Oct 24.

Laboratory of Molecular Immunology and Immunology Center, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1714019114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699083PMC
November 2017

[Professor 's experience in the acupoint selection of clinical treatment with acupuncture and moxibustion].

Zhongguo Zhen Jiu 2017 Nov;37(11):1223-5

College of Acupuncture, Moxibustion and Tuina, Changchun University of TCM, Changchun 130117, Jilin Province, China.

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http://dx.doi.org/10.13703/j.0255-2930.2017.11.023DOI Listing
November 2017

Extraction and in vitro screening of potential acetylcholinesterase inhibitors from the leaves of Panax japonicus.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Sep 12;1061-1062:139-145. Epub 2017 Jul 12.

Central Laboratory, Changchun Normal University, No. 677 North Chang-ji Road, Changchun 130032, China.

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http://dx.doi.org/10.1016/j.jchromb.2017.07.019DOI Listing
September 2017

The cytoplasmic nuclear receptor RARγ controls RIP1 initiated cell death when cIAP activity is inhibited.

Nat Commun 2017 09 4;8(1):425. Epub 2017 Sep 4.

Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-017-00496-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583178PMC
September 2017

An Adaptive and Time-Efficient ECG R-Peak Detection Algorithm.

J Healthc Eng 2017 6;2017:5980541. Epub 2017 Sep 6.

School of Instrument Science and Engineering, Southeast University, Nanjing 210018, China.

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http://dx.doi.org/10.1155/2017/5980541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606151PMC
September 2017

AF Classification from a Short Single Lead ECG Recording: the PhysioNet/Computing in Cardiology Challenge 2017.

Comput Cardiol (2010) 2017 Sep 5;44. Epub 2018 Apr 5.

Institute for Medical Engineering & Science, Massachusetts Institute of Technology, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978770PMC
http://dx.doi.org/10.22489/CinC.2017.065-469DOI Listing
September 2017

Design of a smart ECG garment based on conductive textile electrode and flexible printed circuit board.

Technol Health Care 2017 Aug;25(4):815-821

School of Instrument Science and Engineering, Southeast University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.3233/THC-170828DOI Listing
August 2017

Retrotransposons Are the Major Contributors to the Expansion of the Muller F Element.

Authors:
Wilson Leung Christopher D Shaffer Elizabeth J Chen Thomas J Quisenberry Kevin Ko John M Braverman Thomas C Giarla Nathan T Mortimer Laura K Reed Sheryl T Smith Srebrenka Robic Shannon R McCartha Danielle R Perry Lindsay M Prescod Zenyth A Sheppard Ken J Saville Allison McClish Emily A Morlock Victoria R Sochor Brittney Stanton Isaac C Veysey-White Dennis Revie Luis A Jimenez Jennifer J Palomino Melissa D Patao Shane M Patao Edward T Himelblau Jaclyn D Campbell Alexandra L Hertz Maddison F McEvilly Allison R Wagner James Youngblom Baljit Bedi Jeffery Bettincourt Erin Duso Maiye Her William Hilton Samantha House Masud Karimi Kevin Kumimoto Rebekah Lee Darryl Lopez George Odisho Ricky Prasad Holly Lyn Robbins Tanveer Sandhu Tracy Selfridge Kara Tsukashima Hani Yosif Nighat P Kokan Latia Britt Alycia Zoellner Eric P Spana Ben T Chlebina Insun Chong Harrison Friedman Danny A Mammo Chun L Ng Vinayak S Nikam Nicholas U Schwartz Thomas Q Xu Martin G Burg Spencer M Batten Lindsay M Corbeill Erica Enoch Jesse J Ensign Mary E Franks Breanna Haiker Judith A Ingles Lyndsay D Kirkland Joshua M Lorenz-Guertin Jordan Matthews Cody M Mittig Nicholaus Monsma Katherine J Olson Guillermo Perez-Aragon Alen Ramic Jordan R Ramirez Christopher Scheiber Patrick A Schneider Devon E Schultz Matthew Simon Eric Spencer Adam C Wernette Maxine E Wykle Elizabeth Zavala-Arellano Mitchell J McDonald Kristine Ostby Peter Wendland Justin R DiAngelo Alexis M Ceasrine Amanda H Cox James E B Docherty Robert M Gingras Stephanie M Grieb Michael J Pavia Casey L Personius Grzegorz L Polak Dale L Beach Heaven L Cerritos Edward A Horansky Karim A Sharif Ryan Moran Susan Parrish Kirsten Bickford Jennifer Bland Juliana Broussard Kerry Campbell Katelynn E Deibel Richard Forka Monika C Lemke Marlee B Nelson Catherine O'Keeffe S Mariel Ramey Luke Schmidt Paola Villegas Christopher J Jones Stephanie L Christ Sami Mamari Adam S Rinaldi Ghazal Stity Amy T Hark Mark Scheuerman S Catherine Silver Key Briana D McRae Adam S Haberman Sam Asinof Harriette Carrington Kelly Drumm Terrance Embry Richard McGuire Drew Miller-Foreman Stella Rosen Nadia Safa Darrin Schultz Matt Segal Yakov Shevin Petros Svoronos Tam Vuong Gary Skuse Don W Paetkau Rachael K Bridgman Charlotte M Brown Alicia R Carroll Francesca M Gifford Julie Beth Gillespie Susan E Herman Krystal L Holtcamp Misha A Host Gabrielle Hussey Danielle M Kramer Joan Q Lawrence Madeline M Martin Ellen N Niemiec Ashleigh P O'Reilly Olivia A Pahl Guadalupe Quintana Elizabeth A S Rettie Torie L Richardson Arianne E Rodriguez Mona O Rodriguez Laura Schiraldi Joanna J Smith Kelsey F Sugrue Lindsey J Suriano Kaitlyn E Takach Arielle M Vasquez Ximena Velez Elizabeth J Villafuerte Laura T Vives Victoria R Zellmer Jeanette Hauke Charles R Hauser Karolyn Barker Laurie Cannon Perouza Parsamian Samantha Parsons Zachariah Wichman Christopher W Bazinet Diana E Johnson Abubakarr Bangura Jordan A Black Victoria Chevee Sarah A Einsteen Sarah K Hilton Max Kollmer Rahul Nadendla Joyce Stamm Antoinette E Fafara-Thompson Amber M Gygi Emmy E Ogawa Matt Van Camp Zuzana Kocsisova Judith L Leatherman Cassie M Modahl Michael R Rubin Susana S Apiz-Saab Suzette M Arias-Mejias Carlos F Carrion-Ortiz Patricia N Claudio-Vazquez Debbie M Espada-Green Marium Feliciano-Camacho Karina M Gonzalez-Bonilla Mariela Taboas-Arroyo Dorianmarie Vargas-Franco Raquel Montañez-Gonzalez Joseph Perez-Otero Myrielis Rivera-Burgos Francisco J Rivera-Rosario Heather L Eisler Jackie Alexander Samatha K Begley Deana Gabbard Robert J Allen Wint Yan Aung William D Barshop Amanda Boozalis Vanessa P Chu Jeremy S Davis Ryan N Duggal Robert Franklin Katherine Gavinski Heran Gebreyesus Henry Z Gong Rachel A Greenstein Averill D Guo Casey Hanson Kaitlin E Homa Simon C Hsu Yi Huang Lucy Huo Sarah Jacobs Sasha Jia Kyle L Jung Sarah Wai-Chee Kong Matthew R Kroll Brandon M Lee Paul F Lee Kevin M Levine Amy S Li Chengyu Liu Max Mian Liu Adam P Lousararian Peter B Lowery Allyson P Mallya Joseph E Marcus Patrick C Ng Hien P Nguyen Ruchik Patel Hashini Precht Suchita Rastogi Jonathan M Sarezky Adam Schefkind Michael B Schultz Delia Shen Tara Skorupa Nicholas C Spies Gabriel Stancu Hiu Man Vivian Tsang Alice L Turski Rohit Venkat Leah E Waldman Kaidi Wang Tracy Wang Jeffrey W Wei Dennis Y Wu David D Xiong Jack Yu Karen Zhou Gerard P McNeil Robert W Fernandez Patrick Gomez Menzies Tingting Gu Jeremy Buhler Elaine R Mardis Sarah C R Elgin

G3 (Bethesda) 2017 08 7;7(8):2439-2460. Epub 2017 Aug 7.

Department of Biology, Washington University in St. Louis, St. Louis, MO 63130.

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http://g3journal.org/lookup/doi/10.1534/g3.117.040907
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http://dx.doi.org/10.1534/g3.117.040907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555453PMC
August 2017

Recent advances in heart sound analysis.

Physiol Meas 2017 08 1;38(8):E10-E25. Epub 2017 Aug 1.

Department of Biomedical Informatics, Emory University, Atlanta, GA, United States of America. Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States of America.

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http://dx.doi.org/10.1088/1361-6579/aa7ec8DOI Listing
August 2017

Performance of an open-source heart sound segmentation algorithm on eight independent databases.

Physiol Meas 2017 Aug 1;38(8):1730-1745. Epub 2017 Aug 1.

Department of Biomedical Informatics, Emory University, Atlanta, United States of America.

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http://dx.doi.org/10.1088/1361-6579/aa6e9fDOI Listing
August 2017

MacroH2A1.1 cooperates with EZH2 to promote adipogenesis by regulating Wnt signaling.

J Mol Cell Biol 2017 08;9(4):325-337

Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://dx.doi.org/10.1093/jmcb/mjx027DOI Listing
August 2017

CRISPR-Mediated Knockout of Cybb in NSG Mice Establishes a Model of Chronic Granulomatous Disease for Human Stem-Cell Gene Therapy Transplants.

Hum Gene Ther 2017 07 6;28(7):565-575. Epub 2017 Mar 6.

1 Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases , National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1089/hum.2017.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549813PMC
July 2017

Silencing of astrocyte elevated gene-1 inhibits proliferation and migration of melanoma cells and induces apoptosis.

Clin Exp Pharmacol Physiol 2017 Jul;44(7):815-826

Department of Dermatology, Shengjing Hospital of China Medical University, Shenyang, China.

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http://doi.wiley.com/10.1111/1440-1681.12767
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http://dx.doi.org/10.1111/1440-1681.12767DOI Listing
July 2017

Combining sparse coding and time-domain features for heart sound classification.

Physiol Meas 2017 Jul 31;38(8):1701-1713. Epub 2017 Jul 31.

Department of Electrical and Computer Engineering, Georgia Institute of Technology, GA, United States of America.

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http://dx.doi.org/10.1088/1361-6579/aa7623DOI Listing
July 2017

The role of ZKSCAN3 in the transcriptional regulation of autophagy.

Autophagy 2017 07 5;13(7):1235-1238. Epub 2017 Jun 5.

a Center for Molecular Medicine, National Heart, Lung, and Blood Institute, NIH , Bethesda , MD USA.

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http://dx.doi.org/10.1080/15548627.2017.1320635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529079PMC
July 2017

Combining Low-dimensional Wavelet Features and Support Vector Machine for Arrhythmia Beat Classification.

Sci Rep 2017 07 20;7(1):6067. Epub 2017 Jul 20.

School of Instrument Science and Engineering, Southeast University, Nanjing, 210018, P.R. China.

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http://dx.doi.org/10.1038/s41598-017-06596-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519637PMC
July 2017

A lightweight QRS detector for single lead ECG signals using a max-min difference algorithm.

Comput Methods Programs Biomed 2017 Jun 18;144:61-75. Epub 2017 Mar 18.

Institute for Intelligent Systems Research and Innovation, Deakin University, Waurn Ponds, VIC 3216, Australia.

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http://dx.doi.org/10.1016/j.cmpb.2017.02.028DOI Listing
June 2017

cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma.

Stem Cell Reports 2017 06 25;8(6):1630-1644. Epub 2017 May 25.

Cancer and Stem Cell Epigenetics Section, Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Building 37, Room 3140A, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470112PMC
June 2017

Atrial fibrillation detection on compressed sensed ECG.

Physiol Meas 2017 Jun 27;38(7):1405-1425. Epub 2017 Jun 27.

Department of Biomedical Informatics, Emory University, Atlanta, GA, United States of America. Dipartimento Politecnico di Ingegneria e Architettura, University of Udine, Udine, Italy.

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http://dx.doi.org/10.1088/1361-6579/aa7652DOI Listing
June 2017

Continuous assessment of schizophrenia using heart rate and accelerometer data.

Physiol Meas 2017 Jun 27;38(7):1456-1471. Epub 2017 Jun 27.

Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States of America.

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http://dx.doi.org/10.1088/1361-6579/aa724dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699450PMC
June 2017

Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice.

Nucleic Acids Res 2017 05;45(8):4606-4618

Laboratory of Genetics and Physiology, National Institute of Diabetes, Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/nar/gkx185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416830PMC
May 2017

Cutting Edge: β-Catenin-Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions.

J Immunol 2017 05 27;198(9):3404-3409. Epub 2017 Mar 27.

Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242;

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http://dx.doi.org/10.4049/jimmunol.1602139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423537PMC
May 2017

Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy.

Autophagy 2017 May 2;13(5):941-954. Epub 2017 Mar 2.

b Tongji School of Pharmacy , Huazhong University of Science and Technology , Wuhan , Hubei , China.

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http://dx.doi.org/10.1080/15548627.2017.1293768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446066PMC
May 2017

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.

Nat Commun 2017 05 31;8:15464. Epub 2017 May 31.

Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ncomms15464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460021PMC
May 2017

Oxygen reduction catalyzed by a water-soluble binuclear copper(ii) complex from a neutral aqueous solution.

Chem Commun (Camb) 2017 Mar;53(22):3189-3192

Department of Chemistry, Renmin University of China, Beijing 100872, China. and School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China.

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http://dx.doi.org/10.1039/c6cc09206cDOI Listing
March 2017

Extraction and isolation of potential anti-stroke compounds from flowers of Pueraria lobata guided by in vitro PC12 cell model.

J Chromatogr B Analyt Technol Biomed Life Sci 2017 Mar 14;1048:111-120. Epub 2017 Feb 14.

Central Laboratory, Changchun Normal University, No. 677 North Chang-ji Road, Changchun 130032, China.

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http://dx.doi.org/10.1016/j.jchromb.2017.02.009DOI Listing
March 2017