Chengjie Xiong

Chengjie Xiong

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Chengjie Xiong

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A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials.

Alzheimers Dement 2019 Sep 7. Epub 2019 Sep 7.

Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Departments of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.06.4955DOI Listing
September 2019

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis.

Neurology 2019 Aug 1. Epub 2019 Aug 1.

From the Department of Neurology (S.E.S., J.G.B., V.O., K.G.M., D.M.H., J.C.M., T.L.S.B., C.X., A.M.F., R.J.B.), Knight Alzheimer's Disease Research Center (S.E.S., B.A.G., D.M.H., J.C.M., T.L.S.B., C.X., A.M.F., R.J.B.), Division of Biostatistics (Y.L., C.X.), Mallinckrodt Institute of Radiology (B.A.G., T.L.S.B.), and Hope Center for Neurological Disorders (D.M.H., A.M.F., R.J.B.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000008081DOI Listing
August 2019

Vascular risk factors are associated with longitudinal changes in cerebrospinal fluid tau markers and cognition in preclinical Alzheimer's disease.

Alzheimers Dement 2019 Aug 1. Epub 2019 Aug 1.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.04.015DOI Listing
August 2019

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2019 May 4;15(5):655-665. Epub 2019 Mar 4.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511459PMC
May 2019

Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset.

Alzheimers Dement 2019 Apr 15;15(4):506-514. Epub 2019 Feb 15.

Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461496PMC
April 2019

Incorporating biomarkers to improve statistical power of immunotherapeutic neoadjuvant clinical trials in patients with triple-negative breast cancer.

Stat Biopharm Res 2019 18;11(3):210-219. Epub 2019 Apr 18.

Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1080/19466315.2018.1518259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6714581PMC
April 2019

Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network.

Neurobiol Aging 2019 03 13;75:42-50. Epub 2018 Oct 13.

Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO; Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183037
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385602PMC
March 2019

Dural lymphatics regulate clearance of extracellular tau from the CNS.

Mol Neurodegener 2019 02 27;14(1):11. Epub 2019 Feb 27.

Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University in St. Louis, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1186/s13024-019-0312-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391770PMC
February 2019

Early outcomes of 270-degree spinal canal decompression by using TESSYS-ISEE technique in patients with lumbar spinal stenosis combined with disk herniation.

Eur Spine J 2019 Jan 16;28(1):78-86. Epub 2018 Jun 16.

Orthopaedic Department, Wuhan General Hospital of PLA, #627 Wuluo Road, Hongshan District, Wuhan, Hubei, China.

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http://dx.doi.org/10.1007/s00586-018-5655-4DOI Listing
January 2019

Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies.

Neuroimage Clin 2018 25;19:406-416. Epub 2018 Apr 25.

Department of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.nicl.2018.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051499PMC
January 2019

Cerebrospinal fluid biomarkers measured by Elecsys assays compared to amyloid imaging.

Alzheimers Dement 2018 11 2;14(11):1460-1469. Epub 2018 Mar 2.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119652PMC
November 2018

Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease.

Ann Neurol 2018 11 25;84(5):741-753. Epub 2018 Oct 25.

Knight Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, MO.

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http://dx.doi.org/10.1002/ana.25344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373729PMC
November 2018

Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease.

Alzheimers Dement 2018 11 25;14(11):1427-1437. Epub 2018 Sep 25.

Section for Dementia Research, Department of Cellular Neurology, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.jalz.2018.06.3059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322213PMC
November 2018

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease.

Neurology 2018 10 14;91(14):e1295-e1306. Epub 2018 Sep 14.

From the Department of Neurology (E.M., J.H., V.B., A.M.F., D.M.H., J.C.M., K.P., R.J.B.), Division of Biostatistics (G.W., C.X.), Department of Radiology (B.A.G., T.L.S.B., D.S.M.), and Department of Pathology (N.J.C.), Washington University School of Medicine, Saint Louis, MO; Department of Neuroscience (A.M.J.), Icahn School of Medicine at Mount Sinai, New York, NY; Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (FLENI) (R.A.), Instituto de Investigaciones Neurológicas Raúl Correa, Buenos Aires, Argentina; University of Pittsburgh School of Medicine (S.B.B., W.K.), PA; College of Physicians and Surgeons (J.N.), Columbia University, New York, NY; Department of Neurology (J.R.), Keck School of Medicine of University of Southern California, Los Angeles; Department of Neurology (B.G., M.F.), Indiana University, Indianapolis; Massachusetts General Hospital (R.A.S., J.C.), Harvard Medical School, Boston; Butler Hospital and Brown University (S.S.), Providence, RI; Department of Neurology (N.R.G.-R.), Mayo Clinic Jacksonville, FL; Neuroscience Research Australia (P.R.S.); School of Medical Sciences (P.R.S.), University of New South Wales, Sydney; The Florey Institute and the University of Melbourne (C.M.), Parkville, Australia; Dementia Research Centre, Institute of Neurology (M.N.R., N.C.F.), University College London, UK; German Center for Neurodegenerative Diseases (DZNE) Munich (J.L.); Department of Neurology (J.L.), Ludwig-Maximilians Universität München; German Center for Neurodegenerative Diseases (DZNE) Tübingen (M.J.); and Hertie-Institute for Clinical Brain Research (M.J.), University of Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177272PMC
October 2018

Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease.

Alzheimers Dement 2018 07 23;14(7):869-879. Epub 2018 Mar 23.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110083PMC
July 2018

Upward drift in cerebrospinal fluid amyloid β 42 assay values for more than 10 years.

Alzheimers Dement 2018 01 12;14(1):62-70. Epub 2017 Jul 12.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.06.2264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750131PMC
January 2018

Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals.

Alzheimer Dis Assoc Disord 2017 Jan-Mar;31(1):69-72

*Charles F. and Joanne Knight Alzheimer's Disease Research Center Departments of †Neurology ‡Occupational Therapy ∥Psychology ¶¶Pathology and Immunology ##Physical Therapy **Radiology §§Neurosurgery ∥∥Medicine ¶Center for Clinical Studies #Division of Biostatistics, Washington University School of Medicine, St. Louis, MO §The Rehabilitation Institute of St. Louis ††The Alzheimer's Disease & Memory Disorders Center, Alpert Medical School of Brown University ‡‡Rhode Island Hospital, Providence, Rhode Island.

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http://dx.doi.org/10.1097/WAD.0000000000000154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085874PMC
November 2017

Dynamic Evaluation of the Cervical Spine and the Spinal Cord of Symptomatic Patients Using a Kinetic Magnetic Resonance Imaging Technique.

Clin Spine Surg 2017 Oct;30(8):E1149-E1155

*Orthopedic Department, Wuhan General Hospital of Guangzhou Military Area Command, Wuhan, China †Department of Orthopaedic Surgery, University of Nevada, Las Vegas, NV ‡Department of Orthopaedic Surgery, University of California, Los Angeles §Department of General Surgery, University of California, Irvine, CA ∥Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ¶Department of Orthopaedic Surgery, Houston Methodist Hospital, Houston, TX #Department of Orthopaedic Surgery, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/BSD.0000000000000429DOI Listing
October 2017

Neuropsychological measures that detect early impairment and decline in preclinical Alzheimer disease.

Neurobiol Aging 2017 08 14;56:25-32. Epub 2017 Apr 14.

Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505233PMC
August 2017

Estimating correlation between multivariate longitudinal data in the presence of heterogeneity.

BMC Med Res Methodol 2017 Aug 17;17(1):124. Epub 2017 Aug 17.

Division of Biostatistics, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO, 63110, USA.

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http://bmcmedresmethodol.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12874-017-0398-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561646PMC
August 2017

Validity and power of minimization algorithm in longitudinal analysis of clinical trials.

Biostat Epidemiol 2017 13;1(1):59-77. Epub 2017 Jun 13.

Division of Biostatistics, Washington University in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1080/24709360.2017.1331822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730087PMC
June 2017

A multiple imputation approach to the analysis of clustered interval-censored failure time data with the additive hazards model.

Comput Stat Data Anal 2016 Nov 28;103:242-249. Epub 2016 May 28.

Division of Biostatistics, Washington University School of Medicine, Campus Box 8067, 660 S. Euclid Ave, St. Louis, MO 63110, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072417PMC
http://dx.doi.org/10.1016/j.csda.2016.05.011DOI Listing
November 2016

Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease.

Ann Neurol 2016 09 25;80(3):379-87. Epub 2016 Jul 25.

Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO.

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http://dx.doi.org/10.1002/ana.24719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016232PMC
September 2016

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.

Alzheimers Dement 2016 08 23;12(8):882-9. Epub 2016 Jan 23.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Rush University Medical Center, Department of Neurological Sciences, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958598PMC
August 2016

Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning.

Neurobiol Aging 2016 07 24;43:23-33. Epub 2016 Mar 24.

Charles F. and Joanne Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA; Department of Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA; Department of Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893196PMC
July 2016

Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study.

Neurology 2016 Apr 23;86(16):1499-506. Epub 2016 Mar 23.

From the Charles F. and Joanne Knight Alzheimer's Disease Research Center (C.X., M.S.J., H.W., A.M.F., T.L.S.B., D.H., J.H., E.G., C.L.S., V.B., K.L.M., J.C.M.), Departments of Neurology (V.B., K.L.M., A.M.F., J.H., J.C.M., C.L.S.), Pathology and Immunology (J.C.M.), Physical Therapy (J.C.M.), and Occupational Therapy (J.C.M.), Division of Biostatistics (C.X., M.S.J., H.W., E.G.), and Departments of Psychology (D.H., J.H.), Radiology (T.L.S.B., D.H.), and Neurological Surgery (T.L.S.B.), Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000002593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836885PMC
April 2016

Interrater Reliability of the Record of Driving Errors (RODE).

Am J Occup Ther 2015 Mar-Apr;69(2):6902350020p1-6

Catherine M. Roe, PhD, is Research Assistant Professor, Knight Alzheimer's Disease Research Center and Department of Neurology, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.5014/ajot.2015.013128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406108PMC
December 2015

The evaluation of cervical spine mobility without significant spondylosis by kMRI.

Eur Spine J 2015 Dec 16;24(12):2799-806. Epub 2015 Jul 16.

Spine Center, University of South California, 1520 San Pablo St., Suite 2000, Los Angeles, CA, 90033, USA.

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http://dx.doi.org/10.1007/s00586-015-4101-0DOI Listing
December 2015

Absence of practice effects in preclinical Alzheimer's disease.

Neuropsychology 2015 Nov 25;29(6):940-8. Epub 2015 May 25.

Department of Neurology, Washington University School of Medicine in St. Louis.

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http://dx.doi.org/10.1037/neu0000208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640964PMC
November 2015

Bivariate correlation coefficients in family-type clustered studies.

Biom J 2015 Nov 11;57(6):1084-109. Epub 2015 Sep 11.

Division of Biostatistics, Washington University School of Medicine, 660 S. Euclid Avenue, Box 8067, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1002/bimj.201400131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741284PMC
November 2015

Predicting Clinical Binary Outcome Using Multivariate Longitudinal Data: Application to Patients with Newly Diagnosed Primary Open-Angle Glaucoma.

J Biom Biostat 2015 Oct 26;6(4). Epub 2015 Oct 26.

Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA; Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.4172/2155-6180.1000254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760987PMC
October 2015

A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks.

J Alzheimers Dis 2015 ;44(2):549-60

Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA Geriatric Research, Education and Clinical Center, Veterans Administration Hospital, Madison, WI, USA School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.

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http://dx.doi.org/10.3233/JAD-141626DOI Listing
September 2015

Longitudinal Cerebrospinal Fluid Biomarker Changes in Preclinical Alzheimer Disease During Middle Age.

JAMA Neurol 2015 Sep;72(9):1029-42

Knight Alzheimer's Disease Research Center, Washington University, St Louis, Missouri2Department of Neurology, Washington University, St Louis, Missouri3Hope Center for Neurodegenerative Disorders, Washington University, St Louis, Missouri.

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http://dx.doi.org/10.1001/jamaneurol.2015.1285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570860PMC
September 2015

Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease.

Neurology 2015 Sep 5;85(9):790-8. Epub 2015 Aug 5.

From the Departments of Neurology (F.W., D.C.R., S.M., A.M.F., N.J.C., J.C.M., R.J.B.), Radiology (B.A.G., D.S.M., T.L.S.B.), Biostatistics (C.X.), Psychology (J.H.), Neurological Surgery (T.L.S.B.), and Psychiatry (A.G.), Washington University School of Medicine, Saint Louis, MO; Department of Neurology (E.M.), University of Pittsburgh, PA; Mary S. Easton Center for Alzheimer's Disease Research at UCLA (J.M.R.), Los Angeles, CA; Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; Department of Pathology and Laboratory Medicine (B.G.) and Department of Neurology (M.R.F.), Indiana University School of Medicine, Indianapolis; Center for Alzheimer Research and Treatment (R.S.), Brigham and Women's Hospital and Massachusetts General Hospital, Boston, MA; Department of Neurology (S.S.), Butler Hospital and Warren Alpert Medical School, Brown University, Providence, RI; Neuroscience Research Australia (P.R.S.) and University of New South Wales, Sydney, Australia; Mental Health Research Institute (C.L.M.), University of Melbourne, Parkville, Australia; Centre of Excellence for Alzheimer's Disease Research and Care (R.N.M.), School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Perth, Australia; Dementia Research Centre (M.N.R., C.A.S.L.), UCL Institute of Neurology, London, UK; German Center for Neurodegenerative Diseases (M.J.) and Hertie Institute for Clinical Brain Research, Tübingen, Germany; Neurologische Klinik Ludwig-Maximilians-Universität Munich (A.D.) and German Center for Neurodegenerative Diseases (S.F.), Klinik und Poliklinik für Nuklearmedizin & TUM-Neuroimaging Center, Klinikum rechts der Isar, Technische Universität München, Munich, Germany; and Department of Neurology (F.W.), Xuan Wu Hospital, Capital Medical University, Beijing, China.

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http://dx.doi.org/10.1212/WNL.0000000000001903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553024PMC
September 2015

Cerebrospinal fluid VILIP-1 and YKL-40, candidate biomarkers to diagnose, predict and monitor Alzheimer's disease in a memory clinic cohort.

Alzheimers Res Ther 2015 Sep 17;7(1):59. Epub 2015 Sep 17.

The Knight Alzheimer's Disease Research Center, Washington University School of Medicine, 660 South Euclid, Campus Box 8111, St Louis, 63110, MO, USA.

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http://dx.doi.org/10.1186/s13195-015-0142-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574487PMC
September 2015

Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity.

Curr Alzheimer Res 2014 ;11(9):892-8

Departamento de Neurologia y Neurocirugia, Hospital Clinico Universidad de Chile, Santos Dumont 999, Independencia, Santiago de Chile. CP: 8380430.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378649PMC
July 2015

Subsets of a large cognitive battery better power clinical trials on early stage Alzheimer's disease.

Neuroepidemiology 2014 5;43(2):131-9. Epub 2014 Nov 5.

Division of Biostatistics, Washington University in St. Louis, St. Louis, Mo., USA.

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http://dx.doi.org/10.1159/000365733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237272PMC
July 2015

Pathological correlates of white matter hyperintensities on magnetic resonance imaging.

Dement Geriatr Cogn Disord 2015 8;39(1-2):92-104. Epub 2014 Nov 8.

Department of Neurology, The Catholic University of Korea College of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.1159/000366411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312498PMC
July 2015

Pinocembrin inhibits matrix metalloproteinase expression in chondrocytes.

IUBMB Life 2015 Jan 30;67(1):36-41. Epub 2015 Jan 30.

Department of Orthopedics, Xinqiao Hospital, Third Military Medical University, Chongqing, China.

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http://dx.doi.org/10.1002/iub.1343DOI Listing
January 2015

Diagnostic thresholds with three ordinal groups.

J Biopharm Stat 2014 ;24(3):608-33

a Department of Biostatistics , University at Buffalo , Buffalo , New York , USA.

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http://www.tandfonline.com/doi/abs/10.1080/10543406.2014.888
Publisher Site
http://dx.doi.org/10.1080/10543406.2014.888437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4307385PMC
December 2014

Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice".

Sci Transl Med 2014 Dec;6(268):268lr4

Department of Neurology, Washington University, St. Louis, MO 63110, USA. Knight Alzheimer's Disease Research Center, Washington University Medical Center, St. Louis, MO 63110, USA. Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/scitranslmed.3010609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778730PMC
December 2014

Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis.

Neurology 2014 Jul 13;83(3):253-60. Epub 2014 Jun 13.

From the Departments of Neurology (D.C.R., J.C.M., R.J.B.), Biostatistics (C.X.), and Psychiatry (A.G.), Washington University School of Medicine, St. Louis, MO; Neurologische Klinik Ludwig-Maximilians-Universität Munich and German Center for Neurodegenerative Diseases (A.D.), Munich, Germany; Department of Neurosciences (P.S.A.), University of California San Diego; Mental Health Research Institute (C.L.M.), University of Melbourne, Australia; Grupo de Neurociencias de Antioquia (N.A.-B., F.L., S.M.), Universidad de Antioquia, Medellín, Colombia; Department of Neurology (E.M.), University of Pittsburgh, PA; Department of Neurology (T.B.), University of Washington, Seattle; Banner Alzheimer's Institute (J.B.S.L., E.M.R., P.N.T.), Phoenix, AZ; Neuroscience Research Australia and University of New South Wales (P.R.S.), Sydney, Australia; Edith Cowan University (R.M.), Western Australia; Easton Center for Alzheimer's Disease Research at UCLA (J.M.R.), Los Angeles, CA; Department of Neurology (R.P.M.), Columbia University, New York, NY; Queen Square Institute of Neurology (N.C.F.), University College London; Department of Neurology (S.S.), Warren Alpert Medical School, Brown University, Providence, RI; and Center for Alzheimer Research and Treatment (R.S.), Brigham and Women's Hospital and Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1212/WNL.0000000000000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117367PMC
July 2014

Tumor-suppressing effects of miR-141 in human osteosarcoma.

Cell Biochem Biophys 2014 Jun;69(2):319-25

Department of Orthopedics of Jinling Hospital, Nanjing University, School of Medicine, 305 Zhongshan East Road, Nanjing, 210002, China.

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http://link.springer.com/10.1007/s12013-013-9801-7
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http://dx.doi.org/10.1007/s12013-013-9801-7DOI Listing
June 2014

Migration inhibitory factor enhances inflammation via CD74 in cartilage end plates with Modic type 1 changes on MRI.

Clin Orthop Relat Res 2014 Jun 26;472(6):1943-54. Epub 2014 Feb 26.

Orthopedic Department, Wuhan General Hospital of Guangzhou Military Area Command, Wuhan, China.

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http://dx.doi.org/10.1007/s11999-014-3508-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016425PMC
June 2014

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.

Sci Transl Med 2014 May;6(236):236re4

Department of Neurology, Washington University, St. Louis, MO 63110, USA. Knight Alzheimer's Disease Research Center, Washington University Medical Center, St. Louis, MO 63110, USA. Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1126/scitranslmed.3008169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269372PMC
May 2014

Confidence interval estimation of the difference between two sensitivities to the early disease stage.

Biom J 2014 Mar 22;56(2):270-86. Epub 2013 Nov 22.

Department of Biostatistics, University at Buffalo, Buffalo, NY 14214, USA.

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http://dx.doi.org/10.1002/bimj.201200012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349212PMC
March 2014

APE1/Ref-1 enhances DNA binding activity of mutant p53 in a redox-dependent manner.

Oncol Rep 2014 Feb 2;31(2):901-9. Epub 2013 Dec 2.

Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, P.R. China.

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http://dx.doi.org/10.3892/or.2013.2892DOI Listing
February 2014

Optimizing parameters in clinical trials with a randomized start or withdrawal design.

Comput Stat Data Anal 2014 Jan;69:101-113

Division of Biostatistics, Washington University, St. Louis, USA ; Knight Alzheimer's Disease Research Center, Washington University, St. Louis, MO.

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http://dx.doi.org/10.1016/j.csda.2013.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804275PMC
January 2014

Mated progeny production is a biomarker of aging in Caenorhabditis elegans.

G3 (Bethesda) 2013 Dec 9;3(12):2219-32. Epub 2013 Dec 9.

Department of Developmental, Biology Washington University School of Medicine, St. Louis, Missouri 63110.

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http://dx.doi.org/10.1534/g3.113.008664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852384PMC
December 2013

Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study.

Lancet Neurol 2013 Oct 4;12(10):957-65. Epub 2013 Sep 4.

Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904678PMC
October 2013

The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study.

Neurology 2013 Oct 18;81(16):1425-33. Epub 2013 Sep 18.

From the Dementia Research Centre (D.M.C., Y.L., N.S.R., K.M.K., T.Y., I.B.M., M.N.R., S.O., N.C.F.) and Wellcome Trust Centre for Neuroimaging (G.R.R.), UCL Institute of Neurology, London, UK; Washington University School of Medicine (T.L.S.B., N.J.C., D.S.M., C.X., R.J.B., J.C.M.), St. Louis, MO; Mayo Clinic (C.R.J.), Rochester, MN; Imaging Genetics Center (P.M.T.), Laboratory of Neuroimaging, Department of Neurology & Psychiatry, UCLA School of Medicine, Los Angeles, CA; Indiana University School of Medicine (B.F.G., A.J.S.), Indianapolis; Mental Health Research Institute (C.L.M.), The University Of Melbourne, Victoria, Australia; Mary S. Easton Center for Alzheimer's Disease (J.M.R.), UCLA Department of Neurology, Los Angeles, CA; Butler Hospital (S.P.S.), Providence, RI; Neuroscience Research Australia (P.R.S.), Sydney; and the Center for Alzheimer Research and Treatment (R.A.S.), Brigham and Women's Hospital, Cambridge, MA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806583PMC
October 2013

BMP-2 adverse reactions treated with human dose equivalent dexamethasone in a rodent model of soft-tissue inflammation.

Spine (Phila Pa 1976) 2013 Sep;38(19):1640-7

*Department of Orthopedics, Xinqiao Hospital, Third Military Medical University, Chongqing, People's Republic of China †Department of Orthopaedic Surgery, University of California at Los Angeles (UCLA), Los Angeles, CA; and ‡Orthopaedic Spine Department, Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.

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http://dx.doi.org/10.1097/BRS.0b013e31829cf348DOI Listing
September 2013

Combined use of adenoviral vector Ad5/F35-mediated APE1 siRNA enhances the therapeutic efficacy of adenoviral-mediated p53 gene transfer in hepatoma cells in vitro and in vivo.

Oncol Rep 2013 Jun 4;29(6):2197-204. Epub 2013 Apr 4.

Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing 400042, PR China.

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http://dx.doi.org/10.3892/or.2013.2384DOI Listing
June 2013

Youden index and Associated Cut-points for Three Ordinal Diagnostic Groups.

Commun Stat Simul Comput 2013 Jan;42(6):1213-1234

Division of Biostatistics, Washington University in St. Louis, St. Louis, MO, 63110.

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http://dx.doi.org/10.1080/03610918.2012.661906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685301PMC
January 2013

Missing Data Methods for Partial Correlations.

J Biom Biostat 2012 Dec;3(8)

Division of Biostatistics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.4172/2155-6180.1000155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772686PMC
December 2012

DiagTest3Grp: An R Package for Analyzing Diagnostic Tests with Three Ordinal Groups.

J Stat Softw 2012 Oct 22;51(3):1-24. Epub 2012 Sep 22.

Washington University in St. Louis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595562PMC
October 2012

Optimum Design of Disease-modifying Trials on Alzheimer's Disease.

Stat Biopharm Res 2012 Aug;4(3):216-227

Division of Biostatistics, Washington University, St. Louis, MO 63110 (314) 362 3635 (Office).

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http://dx.doi.org/10.1080/19466315.2011.634757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634601PMC
August 2012