Publications by authors named "Chengdong Li"

7 Publications

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Diabetes-Related Topics in an Online Forum for Caregivers of Individuals Living With Alzheimer Disease and Related Dementias: Qualitative Inquiry.

J Med Internet Res 2020 07 6;22(7):e17851. Epub 2020 Jul 6.

Center on Smart and Connected Health Technologies, School of Nursing, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.

Background: Diabetes and Alzheimer disease and related dementias (ADRD) are the seventh and sixth leading causes of death in the United States, respectively, and they coexist in many older adults. Caring for a loved one with both ADRD and diabetes is challenging and burdensome.

Objective: This study aims to explore diabetes-related topics in the Alzheimer's Association ALZConnected caregiver forum by family caregivers of persons living with ADRD.

Methods: User posts on the Alzheimer's Association ALZConnected caregiver forum were extracted. A total of 528 posts related to diabetes were included in the analysis. Of the users who generated the 528 posts, approximately 96.1% (275/286) were relatives of the care recipient with ADRD (eg, child, grandchild, spouse, sibling, or unspecified relative). Two researchers analyzed the data independently using thematic analysis. Any divergence was discussed among the research team, and an agreement was reached with a senior researcher's input as deemed necessary.

Results: Thematic analysis revealed 7 key themes. The results showed that comorbidities of ADRD were common topics of discussions among family caregivers. Diabetes management in ADRD challenged family caregivers. Family caregivers might neglect their own health care because of the caring burden, and they reported poor health outcomes and reduced quality of life. The online forum provided a platform for family caregivers to seek support in their attempts to learn more about how to manage the ADRD of their care recipients and seek support for managing their own lives as caregivers.

Conclusions: The ALZConnected forum provided a platform for caregivers to seek informational and emotional support for caring for persons living with ADRD and diabetes. The overwhelming burdens with these two health conditions were apparent for both caregivers and care recipients based on discussions from the online forum. Studies are urgently needed to provide practical guidelines and interventions for diabetes management in individuals with diabetes and ADRD. Future studies to explore delivering diabetes management interventions through online communities in caregivers and their care recipients with ADRD and diabetes are warranted.
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http://dx.doi.org/10.2196/17851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381255PMC
July 2020

Development of a Deep Learning Model for Dynamic Forecasting of Blood Glucose Level for Type 2 Diabetes Mellitus: Secondary Analysis of a Randomized Controlled Trial.

JMIR Mhealth Uhealth 2019 11 1;7(11):e14452. Epub 2019 Nov 1.

Center on Smart and Connected Health Technologies, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.

Background: Type 2 diabetes mellitus (T2DM) is a major public health burden. Self-management of diabetes including maintaining a healthy lifestyle is essential for glycemic control and to prevent diabetes complications. Mobile-based health data can play an important role in the forecasting of blood glucose levels for lifestyle management and control of T2DM.

Objective: The objective of this work was to dynamically forecast daily glucose levels in patients with T2DM based on their daily mobile health lifestyle data including diet, physical activity, weight, and glucose level from the day before.

Methods: We used data from 10 T2DM patients who were overweight or obese in a behavioral lifestyle intervention using mobile tools for daily monitoring of diet, physical activity, weight, and blood glucose over 6 months. We developed a deep learning model based on long short-term memory-based recurrent neural networks to forecast the next-day glucose levels in individual patients. The neural network used several layers of computational nodes to model how mobile health data (food intake including consumed calories, fat, and carbohydrates; exercise; and weight) were progressing from one day to another from noisy data.

Results: The model was validated based on a data set of 10 patients who had been monitored daily for over 6 months. The proposed deep learning model demonstrated considerable accuracy in predicting the next day glucose level based on Clark Error Grid and ±10% range of the actual values.

Conclusions: Using machine learning methodologies may leverage mobile health lifestyle data to develop effective individualized prediction plans for T2DM management. However, predicting future glucose levels is challenging as glucose level is determined by multiple factors. Future study with more rigorous study design is warranted to better predict future glucose levels for T2DM management.
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http://dx.doi.org/10.2196/14452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858613PMC
November 2019

Synthesis of Ag/AgCl modified anhydrous basic bismuth nitrate from BiOCl and the antibacterial activity.

Mater Sci Eng C Mater Biol Appl 2019 May 28;98:83-88. Epub 2018 Dec 28.

State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. Electronic address:

Novel nanocomposite of Ag/AgCl and a single phase of anhydrous basic bismuth nitrate (ABBN)-BiO(OH)(NO) with efficient antibacterial activity was prepared from BiOCl. Microstructure was characterized as AgCl nanotubes and Ag nanoparticles mixed with BiO(OH)(NO) nanosheets in nanometer scale. Antibacterial activity of the composite was tested by agar disc diffusion and agar dilution methods using Escherichia coli as target bacteria. The diameter of inhibition zone of Ag/AgCl/ABBN is 17.0 mm while that of bulk BBN is 8.1 mm. The MIC value of Ag/AgCl/ABBN is ascertained as 35 μg mL. Results prove that Ag/AgCl/ABBN nanocomposite has much higher antibacterial activity in comparison with bulk basic bismuth nitrate.
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http://dx.doi.org/10.1016/j.msec.2018.12.116DOI Listing
May 2019

Diabetes Educators' Insights Regarding Connecting Mobile Phone- and Wearable Tracker-Collected Self-Monitoring Information to a Nationally-Used Electronic Health Record System for Diabetes Education: Descriptive Qualitative Study.

JMIR Mhealth Uhealth 2018 Jul 26;6(7):e10206. Epub 2018 Jul 26.

School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.

Background: Diabetes educators are integral to a clinical team in providing diabetes self-management education and support; however, current mobile and Web-based self-management tools are not integrated into clinical diabetes care to support diabetes educators' education efforts.

Objective: The objective of our study was to seek diabetes educators' insights regarding the development of an interface within the Chronicle Diabetes system, a nationally used electronic health record (EHR) system for diabetes education documentation with behavioral goal-setting functions, to transfer mobile phone- and wearable tracker-collected self-monitoring information from patients to diabetes educators to facilitate behavioral goal monitoring.

Methods: A descriptive qualitative study was conducted to seek educators' perspectives on usability and interface development preferences in developing a connected system. Educators can use the Chronicle Diabetes system to set behavioral goals with their patients. Individual and group interviews were used to seek educators' preferences for viewing mobile phone- and wearable tracker-collected information on diet, physical activity, and sleep in the Chronicle Diabetes system using open-ended questions. Interview data were transcribed verbatim and analyzed for common themes.

Results: Five common themes emerged from the discussion. First, educators expressed enthusiasm for and concerns about viewing diet and physical activity data in Chronicle Diabetes system. Second, educators valued viewing detailed dietary macronutrients and activity data; however, they preferred different kinds of details depending on patients' needs, conditions, and behavioral goals and educators' training background. Third, all educators liked the integration of mobile phone-collected data into Chronicle Diabetes system and preferably with current EHR systems. Fourth, a need for a health care team and a central EHR system to be formed was realized for educators to share summaries of self-monitoring data with other providers. Fifth, educators desired advanced features for the mobile app and the connected interface that can show self-monitoring data.

Conclusions: Flexibility is needed for educators to track the details of mobile phone- and wearable tracker-collected diet and activity information, and the integration of such data into Chronicle Diabetes and EHR systems is valuable for educators to track patients' behavioral goals, provide diabetes self-management education and support, and share data with other health care team members to faciliate team-based care in clinical practice.
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http://dx.doi.org/10.2196/10206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085552PMC
July 2018

Enhanced Electrorheological Performance of Nb-Doped TiO2 Microspheres Based Suspensions and Their Behavior Characteristics in Low-Frequency Dielectric Spectroscopy.

ACS Appl Mater Interfaces 2015 Dec 24;7(48):26624-32. Epub 2015 Nov 24.

Laboratory of Functional and Biological Nanomaterials, College of Materials Science and Engineering, Qingdao University of Science and Technology , Qingdao, Shandong 266061, China.

Titanium dioxide and Nb-doped titanium dioxide microspheres with the same size were fabricated by a simple sol-gel method, and the formation mechanism of Nb-doped titanium dioxide microspheres was proposed. Titanium dioxide and Nb-doped titanium dioxide microspheres were adopted as dispersed materials for electrorheological (ER) fluids to investigate the influence of the charge increase introduced by Nb doping on the ER activity. The results showed that Nb doping could effectively enhance the ER performance. Combining with the analysis of dielectric spectroscopy, it was found that the interface polarization of Nb-doped TiO2 ER fluid was larger than that of TiO2 ER fluid, which might be caused by more surface charges in Nb-TiO2 microspheres due to Nb(5+) doping and resulting in enhancement of electric field force and strengthening of fibrous structure. In addition, by comparing and analyzing the permittivity curves of Nb-TiO2/LDPE solid composite and Nb-TiO2/silicone-oil fluid composite, it could be concluded that the enhancement of permittivity at low frequency resulted from the increase of the order degree of dispersed particles in ER fluid rather than from the quasi-dc (QDC) behavior. Moreover, the absolute value of slope of permittivity curves (K) at 0.01 Hz could be utilized as the standard for judging the ability to maintain the chainlike structure. The relationships between polarizability of dispersed particles, dielectric spectrum, parameter K, and ER properties were discussed in detail.
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http://dx.doi.org/10.1021/acsami.5b08155DOI Listing
December 2015

An effective hand vein feature extraction method.

Technol Health Care 2015 ;23 Suppl 2:S343-53

Background: As a new authentication method developed years ago, vein recognition technology features the unique advantage of bioassay.

Objective: This paper studies the specific procedure for the extraction of hand back vein characteristics.

Methods: There are different positions used in the collecting process, so that a suitable intravenous regional orientation method is put forward, allowing the positioning area to be the same for all hand positions. In addition, to eliminate the pseudo vein area, the valley regional shape extraction operator can be improved and combined with multiple segmentation algorithms. The images should be segmented step by step, making the vein texture to appear clear and accurate. Lastly, the segmented images should be filtered, eroded, and refined. This process helps to filter the most of the pseudo vein information.

Results: Finally, a clear vein skeleton diagram is obtained, demonstrating the effectiveness of the algorithm.

Conclusion: This paper presents a hand back vein region location method. This makes it possible to rotate and correct the image by working out the inclination degree of contour at the side of hand back.
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http://dx.doi.org/10.3233/THC-150971DOI Listing
July 2016

Type-II core-shell Si-CdS nanocrystals: synthesis and spectroscopic and electrical properties.

Chem Commun (Camb) 2014 Oct;50(80):11922-5

State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing 210093, P. R. China.

Type-II Si-CdS core-shell colloidal nanocrystals (NCs) are synthesized with the spectroscopic and electronic properties tuned by the thickness of the CdS shell.
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http://dx.doi.org/10.1039/c4cc04722bDOI Listing
October 2014