Publications by authors named "Cheng Kian Kai"

27Publications

Suppresses Inflammation and Glycolysis in Lipopolysaccharide-Activated RAW264.7 Macrophages.

Molecules 2020 Aug 20;25(17). Epub 2020 Aug 20.

Innovation Centre in Agritechnology, Universiti Teknologi Malaysia, Pagoh 84600, Johor, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules25173783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504525PMC
August 2020

Identifying Significant Metabolic Pathways Using Multi-Block Partial Least-Squares Analysis.

J Proteome Res 2020 May 27;19(5):1965-1974. Epub 2020 Mar 27.

Department of Electronic Science, Xiamen University, Xiamen 361005, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jproteome.9b00793DOI Listing
May 2020

H NMR-Based Metabolic Profiles Delineate the Anticancer Effect of Vitamin C and Oxaliplatin on Hepatocellular Carcinoma Cells.

J Proteome Res 2020 02 23;19(2):781-793. Epub 2020 Jan 23.

Department of Electronic Science, Fujian Provincial Key Laboratory for Plasma and Magnetic Resonance , Xiamen University , Xiamen , Fujian 361005 , China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jproteome.9b00635DOI Listing
February 2020

Deciphering the metabolic perturbation in hepatic alveolar echinococcosis: a H NMR-based metabolomics study.

Parasit Vectors 2019 Jun 13;12(1):300. Epub 2019 Jun 13.

Department of Electronic Science, Fujian Provincial Key Laboratory for Plasma and Magnetic Resonance, Xiamen University, Xiamen, 361005, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13071-019-3554-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567409PMC
June 2019

Metabolic Response in Rats following Electroacupuncture or Moxibustion Stimulation.

Evid Based Complement Alternat Med 2019 2;2019:6947471. Epub 2019 May 2.

Department of Electronic Science, Fujian Provincial Key Laboratory for Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/6947471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521395PMC
May 2019

Metabolic Effect of Dietary Taurine Supplementation on Nile Tilapia (Oreochromis nilotictus) Evaluated by NMR-Based Metabolomics.

J Agric Food Chem 2018 Jan 20;66(1):368-377. Epub 2017 Dec 20.

Fisheries College, Xiamen Key Laboratory for Feed Quality Testing and Safety Evaluation, Jimei University , Xiamen 361021, China.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.jafc.7b03182
Publisher Site
http://dx.doi.org/10.1021/acs.jafc.7b03182DOI Listing
January 2018

H NMR-based Investigation of Metabolic Response to Electro-Acupuncture Stimulation.

Sci Rep 2017 07 28;7(1):6820. Epub 2017 Jul 28.

Department of Electronic Science, Fujian Provincial Key Laboratory for Plasma and Magnetic Resonance, Xiamen University, Xiamen, 361005, China.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41598-017-07306-5
Publisher Site
http://dx.doi.org/10.1038/s41598-017-07306-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533752PMC
July 2017

NMR-based metabolomics Reveals Alterations of Electro-acupuncture Stimulations on Chronic Atrophic Gastritis Rats.

Sci Rep 2017 03 30;7:45580. Epub 2017 Mar 30.

Department of Electronic Science, and Department of Traditional Chinese Medicine, Xiamen University, Xiamen 361005, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep45580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372362PMC
March 2017

Metabolomics, Lipidomics and Pharmacometabolomics of Human Hypertension.

Adv Exp Med Biol 2017 ;956:599-613

Centre for Biodiversity Research, Universiti Tunku Abdul Rahman, Bandar Barat, 31900, Kampar, Perak, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/5584_2016_79DOI Listing
October 2017

The Influence of OLR1 and PCSK9 Gene Polymorphisms on Ischemic Stroke: Evidence from a Meta-Analysis.

Sci Rep 2015 Dec 15;5:18224. Epub 2015 Dec 15.

Centre for Biodiversity Research, Universiti Tunku Abdul Rahman, Bandar Barat, 31900 Kampar, Perak, Malaysia.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/srep18224
Publisher Site
http://dx.doi.org/10.1038/srep18224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678327PMC
December 2015

(1) H NMR Metabolic Profiling of Biofluids from Rats with Gastric Mucosal Lesion and Electroacupuncture Treatment.

Evid Based Complement Alternat Med 2015 15;2015:801691. Epub 2015 Jun 15.

Department of Electronic Science and Department of Traditional Chinese Medicine, Xiamen University, Xiamen 361005, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2015/801691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4485499PMC
July 2015

Celastrol Protects against Antimycin A-Induced Insulin Resistance in Human Skeletal Muscle Cells.

Molecules 2015 May 7;20(5):8242-69. Epub 2015 May 7.

Department of Pharmacy, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules20058242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272652PMC
May 2015

Metabolomics - the complementary field in systems biology: a review on obesity and type 2 diabetes.

Mol Biosyst 2015 Jul;11(7):1742-74

Department of Bioprocess Engineering, Faculty of Chemical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Johor, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c5mb00158gDOI Listing
July 2015

1H NMR-based metabolomics investigation of copper-laden rat: a model of Wilson's disease.

PLoS One 2015 7;10(4):e0119654. Epub 2015 Apr 7.

Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen, 361005, P. R. China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0119654PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388371PMC
April 2016

[A novel metabolomic data scaling method based on K-L divergence].

Guang Pu Xue Yu Guang Pu Fen Xi 2014 Oct;34(10):2868-72

View Article

Download full-text PDF

Source
October 2014

Amelioration of mitochondrial dysfunction-induced insulin resistance in differentiated 3T3-L1 adipocytes via inhibition of NF-κB pathways.

Int J Mol Sci 2014 Dec 2;15(12):22227-57. Epub 2014 Dec 2.

Innovation Centre in Agritechnology for Advanced Bioprocessing (ICA), University Teknologi Malaysia, Skudai 81310, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms151222227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284705PMC
December 2014

Metabolomic analysis of akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation.

J Proteome Res 2015 Jan 22;14(1):342-52. Epub 2014 Oct 22.

Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge , Cambridge CB2 1GA, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr500756uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286153PMC
January 2015

Mitochondrial dysfunction as a central event for mechanisms underlying insulin resistance: the roles of long chain fatty acids.

Diabetes Metab Res Rev 2015 Jul 18;31(5):453-75. Epub 2014 Oct 18.

Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dmrr.2601DOI Listing
July 2015

Global metabolic network reorganization by adaptive mutations allows fast growth of Escherichia coli on glycerol.

Nat Commun 2014 ;5:3233

1] Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan [2] Systems Biology Program, Graduate School of Media and Governance, Keio University, Fujisawa, Kanagawa 252-8520, Japan [3].

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ncomms4233
Publisher Site
http://dx.doi.org/10.1038/ncomms4233DOI Listing
October 2015

The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice.

Free Radic Biol Med 2012 Mar 14;52(5):841-9. Epub 2011 Dec 14.

Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.freeradbiomed.2011.11.026DOI Listing
March 2012

The study of mammalian metabolism through NMR-based metabolomics.

Methods Enzymol 2011 ;500:337-51

Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-385118-5.00017-7DOI Listing
January 2012

DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome.

Circ Res 2010 Oct 12;107(8):1021-31. Epub 2010 Aug 12.

Division of Cardiovascular Medicine, University of Cambridge, Box 110, Addenbrooke's Hospital, Cambridge, CB2 2QQ, United Kingdom.

View Article

Download full-text PDF

Source
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.110.21896
Publisher Site
http://dx.doi.org/10.1161/CIRCRESAHA.110.218966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982998PMC
October 2010

Metabolomic strategies to study lipotoxicity in cardiovascular disease.

Biochim Biophys Acta 2010 Mar 26;1801(3):230-4. Epub 2009 Nov 26.

Department of Biochemistry, University of Cambridge, and Metabolic Research Laboratories, Institute of Metabolic Sciences, Addenbrooke's Hospital, Cambridge, CB2 1QW, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2009.11.004DOI Listing
March 2010

Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse.

Mol Syst Biol 2009 7;5:259. Epub 2009 Apr 7.

Department of Biochemistry & Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/msb.2009.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683722PMC
June 2009