Chen-Ming Fan

Chen-Ming Fan

UNVERIFIED PROFILE

Are you Chen-Ming Fan?   Register this Author

Register author
Chen-Ming Fan

Chen-Ming Fan

Publications by authors named "Chen-Ming Fan"

Are you Chen-Ming Fan?   Register this Author

50Publications

511Reads

6Profile Views

A CREB-MPP7-AMOT Regulatory Axis Controls Muscle Stem Cell Expansion and Self-Renewal Competence.

Cell Rep 2017 Oct;21(5):1253-1266

Department of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA; Department of Embryology, Carnegie Institution for Science, 3520 San Martin Drive, Baltimore, MD 21218, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2017.10.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710848PMC
October 2017

Quantitative 3D Time Lapse Imaging of Muscle Progenitors in Skeletal Muscle of Live Mice.

Bio Protoc 2016 Dec;6(24)

Department of Embryology, Carnegie Institution for Science, Baltimore, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21769/BioProtoc.2066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391799PMC
December 2016

Genetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis.

Oncotarget 2016 Nov;7(48):79233-79246

Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Guy's Hospital, SE1 9RT, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.13011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346710PMC
November 2016

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice.

Nat Med 2016 08 4;22(8):889-96. Epub 2016 Jul 4.

Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.4116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974124PMC
August 2016

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration.

Cell Stem Cell 2016 Feb 10;18(2):243-52. Epub 2015 Dec 10.

Department of Embryology, Carnegie Institution of Washington, 3520 San Martin Drive, Baltimore, MD 21218, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2015.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744135PMC
February 2016

Growth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in Mice.

Biol Reprod 2016 Feb 6;94(2):44. Epub 2016 Jan 6.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1095/biolreprod.115.133058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787628PMC
February 2016

WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals.

Development 2015 Apr;142(7):1254-66

Division of Nephrology, Department of Medicine, Boston Children's Hospital, Boston, MA 02115, USA Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA Harvard Stem Cell Institute, Cambridge, MA 02138, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.119735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378252PMC
April 2015

Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.

Cancer Res 2015 Feb 12;75(3):605-14. Epub 2014 Dec 12.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina. Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-14-2527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327867PMC
February 2015

Gas1 is a receptor for sonic hedgehog to repel enteric axons.

Proc Natl Acad Sci U S A 2015 Jan 22;112(1):E73-80. Epub 2014 Dec 22.

Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21218; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1418629112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291612PMC
January 2015

HDAC4 promotes Pax7-dependent satellite cell activation and muscle regeneration.

EMBO Rep 2014 Nov 9;15(11):1175-83. Epub 2014 Sep 9.

Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embr.201439195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253491PMC
November 2014

A series of Cre-ER(T2) drivers for manipulation of the skeletal muscle lineage.

Genesis 2014 Aug 3;52(8):759-70. Epub 2014 Jun 3.

Department of Embryology, Carnegie Institution for Science, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dvg.22792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441791PMC
August 2014

Boc modifies the spectrum of holoprosencephaly in the absence of Gas1 function.

Biol Open 2014 Jul 25;3(8):728-40. Epub 2014 Jul 25.

Department of Craniofacial Development and Stem Cell Biology, King's College London Dental Institute, Guy's Hospital, London SE1 9RT, UK Department of Orthodontics, King's College London Dental Institute, Guy's Hospital, London SE1 9RT, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/bio.20147989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133726PMC
July 2014

c-MET regulates myoblast motility and myocyte fusion during adult skeletal muscle regeneration.

PLoS One 2013 19;8(11):e81757. Epub 2013 Nov 19.

Department of Embryology, The Carnegie Institution for Science, Baltimore, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081757PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834319PMC
June 2014

Making skeletal muscle from progenitor and stem cells: development versus regeneration.

Wiley Interdiscip Rev Dev Biol 2012 May-Jun;1(3):315-27

Department of Embryology, Carnegie Institution of Washington, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/wdev.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378334PMC
April 2014

Myf5-positive satellite cells contribute to Pax7-dependent long-term maintenance of adult muscle stem cells.

Cell Stem Cell 2013 Nov 8;13(5):590-601. Epub 2013 Aug 8.

Department of Cardiac Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Ludwigstraße 43, 61231 Bad Nauheim, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2013.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082715PMC
November 2013

Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells.

Cell Rep 2013 Nov 14;5(4):933-40. Epub 2013 Nov 14.

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA; Program in Molecular Cancer Biology, Duke University, Durham, NC 27710, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2013.10.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893104PMC
November 2013

Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion.

Development 2013 Jul 12;140(14):2972-84. Epub 2013 Jun 12.

Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London SE1 1UL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.090050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699282PMC
July 2013

Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis.

Proc Natl Acad Sci U S A 2013 May 13;110(22):E2019-27. Epub 2013 May 13.

Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1222115110
Publisher Site
http://dx.doi.org/10.1073/pnas.1222115110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670316PMC
May 2013

Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling.

Biol Open 2013 Feb 20;2(2):144-55. Epub 2012 Nov 20.

Department of Embryology, Carnegie Institution of Washington , 3520 San Martin Drive, Baltimore, Maryland 21218 , USA ; 2iE Foundation, International Institute for Water and Environmental Engineering , Rue de la Science, 01 BP 594, Ouagadougou 01 , Burkina Faso.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/bio.20123186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575649PMC
February 2013

Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway.

Proc Natl Acad Sci U S A 2012 Aug 6;109(35):E2353-60. Epub 2012 Aug 6.

Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1206410109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435227PMC
August 2012

A transgenic Tbx6;CreERT2 line for inducible gene manipulation in the presomitic mesoderm.

Genesis 2012 Jun 27;50(6):490-5. Epub 2011 Dec 27.

Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dvg.20827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3329572PMC
June 2012

Generating tamoxifen-inducible Cre alleles to investigate myogenesis in mice.

Methods Mol Biol 2012 ;798:297-308

Department of Embryology, Carnegie Institution of Washington, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-61779-343-1_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695624PMC
April 2012

Missense substitutions in the GAS1 protein present in holoprosencephaly patients reduce the affinity for its ligand, SHH.

Hum Genet 2012 Feb 13;131(2):301-10. Epub 2011 Aug 13.

Medical Genetics Branch, National Human Genome Research Institute (NHGRI), National Institutes of Health, Bethesda, MD 20892-3717, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-011-1078-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695622PMC
February 2012

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration.

Development 2011 Sep;138(17):3639-46

Department of Embryology, Carnegie Institution for Science, 3520 San Martin Drive, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.067595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152922PMC
September 2011

Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells.

Genesis 2010 Jul;48(7):424-36

Department of Embryology, Carnegie Institution, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/dvg.20630
Publisher Site
http://dx.doi.org/10.1002/dvg.20630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113517PMC
July 2010

A role for borg5 during trophectoderm differentiation.

Stem Cells 2010 Jun;28(6):1030-8

Department of Embryology, Carnegie Institution for Science, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/stem.428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957878PMC
June 2010

Counterfeiting the family jewels.

Cell Stem Cell 2010 May;6(5):405-6

Department of Embryology, Carnegie Institution, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2010.04.012DOI Listing
May 2010

A sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1.

J Biol Chem 2009 Jul 28;284(29):19169-72. Epub 2009 May 28.

Department of Embryology, Carnegie Institution for Science, Baltimore, Maryland 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.C109.011957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740538PMC
July 2009

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements.

Nature 2009 Jul;460(7255):627-31

Department of Embryology, Carnegie Institution, 3520 San Martin Drive, Baltimore, Maryland 21218, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nature08209
Publisher Site
http://dx.doi.org/10.1038/nature08209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767162PMC
July 2009

Primary cilia regulate Shh activity in the control of molar tooth number.

Development 2009 Mar 11;136(6):897-903. Epub 2009 Feb 11.

Department of Craniofacial Development, Dental Institute, King's College London, London SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.027979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727556PMC
March 2009

V3 spinal neurons establish a robust and balanced locomotor rhythm during walking.

Neuron 2008 Oct;60(1):84-96

Molecular Neurobiology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2008.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753604PMC
October 2008

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

Gene Expr Patterns 2008 Sep 21;8(7-8):502-7. Epub 2008 Jun 21.

Department of Embryology, Carnegie Institution of Washington, 3520 San Martin Drive, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gep.2008.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617776PMC
September 2008

The role of Gas1 in embryonic development and its implications for human disease.

Cell Cycle 2007 Nov 13;6(21):2650-5. Epub 2007 Aug 13.

Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cc.6.21.4877DOI Listing
November 2007

Separate necdin domains bind ARNT2 and HIF1alpha and repress transcription.

Biochem Biophys Res Commun 2007 Nov 29;363(1):113-8. Epub 2007 Aug 29.

Department of Embryology, Carnegie Institution of Washington, 3520 San Martin Drive, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2007.08.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2083645PMC
November 2007

Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.

J Clin Invest 2007 Jun 24;117(6):1575-84. Epub 2007 May 24.

Department of Craniofacial Development, Dental Institute, King's College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI32032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868789PMC
June 2007

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

Mol Endocrinol 2007 May 13;21(5):1234-45. Epub 2007 Mar 13.

Department of Embryology, Carnegie Institution of Washington, 3520 San Martin Drive, Baltimore, Maryland 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2007-0034DOI Listing
May 2007

Gas1 extends the range of Hedgehog action by facilitating its signaling.

Genes Dev 2007 May;21(10):1231-43

Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1546307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865494PMC
May 2007

Targeting gene expression in the mouse somite: adenovirus-mediated gene delivery and whole embryo culture.

Genesis 2005 Jun;42(2):71-6

Department of Embryology, Carnegie Institution of Washington, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gene.20126DOI Listing
June 2005

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins.

Nature 2005 Jan 28;433(7023):317-22. Epub 2004 Nov 28.

Department of Embryology, Carnegie Institution of Washington, 115 West University Parkway, Baltimore, Maryland 21210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature03126DOI Listing
January 2005

Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus.

Mol Endocrinol 2004 May 26;18(5):1251-62. Epub 2004 Feb 26.

Department of Embryology, Carnegie Institution of Washington, 115 West University Parkway, Baltimore, Maryland 21210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2003-0372DOI Listing
May 2004

Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.

Development 2003 Dec 5;130(25):6233-43. Epub 2003 Nov 5.

Department of Embryology, Carnegie Institution of Washington, 115 West University Parkway, Baltimore, MD 21210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.00851DOI Listing
December 2003

Identification of the downstream targets of SIM1 and ARNT2, a pair of transcription factors essential for neuroendocrine cell differentiation.

J Biol Chem 2003 Nov 28;278(45):44857-67. Epub 2003 Aug 28.

Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M304489200DOI Listing
November 2003

Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm.

Dev Biol 2003 Jun;258(1):91-104

Carnegie Institution of Washington, Department of Embryology, Baltimore, MD 21210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0012-1606(03)00116-7DOI Listing
June 2003

Growth arrest specific gene 1: a fuel for driving growth in the cerebellum.

Cerebellum 2002 Dec;1(4):259-63

Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/147342202320883560DOI Listing
December 2002

Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb.

Development 2002 Nov;129(22):5289-300

Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210, USA.

View Article

Download full-text PDF

Source
November 2002

Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants.

Mol Cell Biol 2002 Jun;22(12):4147-57

Department of Embryology, Carnegie Institution of Washington, Baltimore, Maryland 21210, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC133848PMC
http://dx.doi.org/10.1128/mcb.22.12.4147-4157.2002DOI Listing
June 2002