Charlotte Bauer

Charlotte Bauer

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Charlotte Bauer

Charlotte Bauer

Publications by authors named "Charlotte Bauer"

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Intraneuronal accumulation of C99 contributes to synaptic alterations, apathy-like behavior, and spatial learning deficits in 3×TgAD and 2×TgAD mice.

Authors:
Alexandre Bourgeois Inger Lauritzen Thomas Lorivel Charlotte Bauer Frédéric Checler Raphaëlle Pardossi-Piquard

Neurobiol Aging 2018 11 12;71:21-31. Epub 2018 Jul 12.

Université Côte d'Azur, INSERM, CNRS, IPMC, UMR7275, Team labeled « Laboratory of Excellence (Labex) DISTALZ», Sophia-Antipolis, Valbonne, France. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.06.038DOI Listing
November 2018

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes.

Authors:
Dolores Del Prete Jan M Suski Bénédicte Oulès Delphine Debayle Anne Sophie Gay Sandra Lacas-Gervais Renaud Bussiere Charlotte Bauer Paolo Pinton Patrizia Paterlini-Bréchot Mariusz R Wieckowski Frédéric Checler Mounia Chami

J Alzheimers Dis 2017 ;55(4):1549-1570

Université Côte d'Azur, INSERM, CNRS, IPMC, France, Laboratory of Excellence DistALZ, Sophia-Antipolis, Valbonne, France.

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http://dx.doi.org/10.3233/JAD-160953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181669PMC
February 2018

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.

Authors:
Alain Lacampagne Xiaoping Liu Steven Reiken Renaud Bussiere Albano C Meli Inger Lauritzen Andrew F Teich Ran Zalk Nathalie Saint Ottavio Arancio Charlotte Bauer Fabrice Duprat Clark A Briggs Shreaya Chakroborty Grace E Stutzmann Michael L Shelanski Frederic Checler Mounia Chami Andrew R Marks

Acta Neuropathol 2017 11 19;134(5):749-767. Epub 2017 Jun 19.

Department of Physiology and Cellular Biophysics, Clyde and Helen Wu Center for Molecular Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA.

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http://dx.doi.org/10.1007/s00401-017-1733-7DOI Listing
November 2017

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.

Authors:
Julien Chapuis Amandine Flaig Benjamin Grenier-Boley Fanny Eysert Virginie Pottiez Gaspard Deloison Alexandre Vandeputte Anne-Marie Ayral Tiago Mendes Shruti Desai Alison M Goate John S K Kauwe Florence Leroux Adrien Herledan Florie Demiautte Charlotte Bauer Fréderic Checler Ronald C Petersen Kaj Blennow Henrik Zetterberg Lennart Minthon Vivianna M Van Deerlin Virginia Man-Yee Lee Leslie M Shaw John Q Trojanowski Marilyn Albert Abhay Moghekar Richard O'Brien Elaine R Peskind Nicolas Malmanche Gerard D Schellenberg Pierre Dourlen Ok-Ryul Song Carlos Cruchaga Philippe Amouyel Benoit Deprez Priscille Brodin Jean-Charles Lambert

Acta Neuropathol 2017 06 8;133(6):955-966. Epub 2016 Dec 8.

Laboratoire d'Excellence Distalz, Univ. Lille, Unité INSERM 1167, Institut Pasteur de Lille, BP 245, 1 rue du professeur Calmette, 59000, Lille cedex, France.

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http://dx.doi.org/10.1007/s00401-016-1652-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5427165PMC
June 2017

MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking .

Authors:
Kévin Baranger Amandine E Bonnet Stéphane D Girard Jean-Michel Paumier Laura García-González Wejdane Elmanaa Anne Bernard Eliane Charrat Delphine Stephan Charlotte Bauer Katrin Moschke Stefan F Lichtenthaler François S Roman Frédéric Checler Michel Khrestchatisky Santiago Rivera

Front Mol Neurosci 2016 10;9:163. Epub 2017 Jan 10.

Aix Marseille Université, CNRS, NICN UMR 7259 Marseille, France.

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http://dx.doi.org/10.3389/fnmol.2016.00163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223243PMC
January 2017

Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1.

Authors:
Yannis Gerakis Julie Dunys Charlotte Bauer Fréderic Checler

Sci Rep 2016 11 17;6:37436. Epub 2016 Nov 17.

Université Côte d'Azur, INSERM, CNRS, IPMC, France, Laboratory of excellence DistALZ, 660 route des Lucioles, 06560, Sophia-Antipolis, Valbonne, France.

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http://dx.doi.org/10.1038/srep37436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112606PMC
November 2016

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.

Authors:
Inger Lauritzen Raphaëlle Pardossi-Piquard Alexandre Bourgeois Sophie Pagnotta Maria-Grazia Biferi Martine Barkats Pascale Lacor William Klein Charlotte Bauer Frederic Checler

Acta Neuropathol 2016 08 30;132(2):257-276. Epub 2016 Apr 30.

Université de Nice-Sophia-Antipolis, Institut de Pharmacologie Moléculaire et Cellulaire, CNRS-UMR7275, Team Labelised Fondation pour la Recherche Médicale et Laboratoire d'excellence Distalz, Sophia-Antipolis, France.

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http://dx.doi.org/10.1007/s00401-016-1577-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947121PMC
August 2016

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease.

Authors:
Florent Letronne Geoffroy Laumet Anne-Marie Ayral Julien Chapuis Florie Demiautte Mathias Laga Michel E Vandenberghe Nicolas Malmanche Florence Leroux Fanny Eysert Yoann Sottejeau Linda Chami Amandine Flaig Charlotte Bauer Pierre Dourlen Marie Lesaffre Charlotte Delay Ludovic Huot Julie Dumont Elisabeth Werkmeister Franck Lafont Tiago Mendes Franck Hansmannel Bart Dermaut Benoit Deprez Anne-Sophie Hérard Marc Dhenain Nicolas Souedet Florence Pasquier David Tulasne Claudine Berr Jean-Jacques Hauw Yves Lemoine Philippe Amouyel David Mann Rebecca Déprez Frédéric Checler David Hot Thierry Delzescaux Kris Gevaert Jean-Charles Lambert

EBioMedicine 2016 Jul 2;9:278-292. Epub 2016 Jun 2.

INSERM, U1167, Laboratoire d'Excellence Distalz, F59000 Lille, France; Institut Pasteur de Lille, F59000 Lille, France; Univ. Lille, F59000 Lille, France. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972530PMC
July 2016

MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.

Authors:
Kévin Baranger Yannick Marchalant Amandine E Bonnet Nadine Crouzin Alex Carrete Jean-Michel Paumier Nathalie A Py Anne Bernard Charlotte Bauer Eliane Charrat Katrin Moschke Mothoharu Seiki Michel Vignes Stefan F Lichtenthaler Frédéric Checler Michel Khrestchatisky Santiago Rivera

Cell Mol Life Sci 2016 Jan 23;73(1):217-36. Epub 2015 Jul 23.

Aix-Marseille Université, CNRS, NICN UMR 7259, 13344, Marseille, France.

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http://dx.doi.org/10.1007/s00018-015-1992-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700096PMC
January 2016

Study on Aβ34 biology and detection in transgenic mice brains.

Authors:
Céline Caillava Sébastien Ranaldi Inger Lauritzen Charlotte Bauer Jeannette Fareh Jean-Daniel Abraham Frédéric Checler

Neurobiol Aging 2014 Jul 11;35(7):1570-81. Epub 2014 Jan 11.

Institut de Pharmacologie Moléculaire et Cellulaire, UMR7275 CNRS/UNS, Team "Fondation pour la Recherche Médicale" and "Labex Distalz", Valbonne, France. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.011DOI Listing
July 2014

Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.

Authors:
Eric Duplan Jean Sevalle Julien Viotti Thomas Goiran Charlotte Bauer Paul Renbaum Ephrat Levy-Lahad Clément A Gautier Olga Corti Nathalie Leroudier Frédéric Checler Cristine Alves da Costa

J Mol Cell Biol 2013 Apr 28;5(2):132-42. Epub 2013 Jan 28.

Institut de Pharmacologie Moléculaire et Cellulaire, UMR7275 CNRS/UNSA, Sophia-Antipolis, Valbonne 06560, France.

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http://dx.doi.org/10.1093/jmcb/mjt003DOI Listing
April 2013

The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus.

Authors:
Inger Lauritzen Raphaëlle Pardossi-Piquard Charlotte Bauer Elizabeth Brigham Jean-Daniel Abraham Sébastien Ranaldi Paul Fraser Peter St-George-Hyslop Ophelia Le Thuc Vanessa Espin Linda Chami Julie Dunys Frédéric Checler

J Neurosci 2012 Nov;32(46):16243-1655a

Université de Nice-Sophia-Antipolis, Institut de Pharmacologie Moléculaire et Cellulaire, CNRS-UMR7275, team labelised «Fondation pour la Recherche Médicale» et "Laboratoire d'excellence Distalz", Sophia-Antipolis, France.

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http://dx.doi.org/10.1523/JNEUROSCI.2775-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019353PMC
November 2012

γ-Secretase-mediated regulation of neprilysin: influence of cell density and aging and modulation by imatinib.

Authors:
Charlotte Bauer Raphaëlle Pardossi-Piquard Julie Dunys Maggie Roy Frédéric Checler

J Alzheimers Dis 2011 ;27(3):511-20

Institut de Pharmacologie Moléculaire et Cellulaire and Institut de NeuroMédecine Moléculaire, team labeled Fondation pour la Recherche Médicale, Valbonne, France.

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http://dx.doi.org/10.3233/JAD-2011-110746DOI Listing
August 2012

α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death.

Authors:
Marie-Victoire Guillot-Sestier Claire Sunyach Sergio T Ferreira Maria-Paz Marzolo Charlotte Bauer Aurélie Thevenet Frédéric Checler

J Biol Chem 2012 Feb 19;287(7):5021-32. Epub 2011 Dec 19.

Institut de Pharmacologie Moléculaire et Cellulaire, UMR6097 CNRS/Université de Nice-Sophia-Antipolis (UNSA), 660 route des Lucioles, Sophia-Antipolis, 06560 Valbonne, France.

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http://dx.doi.org/10.1074/jbc.M111.323626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281657PMC
February 2012

The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.

Authors:
Moustapha Cissé Eric Duplan Marie-Victoire Guillot-Sestier Joaquim Rumigny Charlotte Bauer Gilles Pagès Hans-Dieter Orzechowski Barbara E Slack Frédéric Checler Bruno Vincent

J Biol Chem 2011 Aug 17;286(33):29192-206. Epub 2011 May 17.

Institut de Pharmacologie Moléculaire et Cellulaire, Unité Mixte de Recherche, 6097 Centre National de la Recherche Scientifique/Université de Nice-Sophia-Antipolis, Equipe labellisée Fondation pour la Recherche Médicale, 660 route des lucioles, Sophia-Antipolis, 06560 Valbonne, France.

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http://dx.doi.org/10.1074/jbc.M110.208249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190726PMC
August 2011