Charles van der Horst

Charles van der Horst

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Charles van der Horst

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Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.

N Engl J Med 2018 03;378(11):1004-1017

From the Centre for Global Health, Institute for Infection and Immunity, St. George's University of London (S.F.M., A.L., N.S., N. Karunaharan, J.A., T.B., T.S.H.), University College London (R.S.H.), and the MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine (J.B.), London, and Liverpool School of Tropical Medicine, Liverpool (T.C., D.G.L., D.W., S.J.) - all in the United Kingdom; the University of North Carolina Project-Malawi, Kamuzu Central Hospital, Lilongwe (C. Kanyama, C.C., C.H., M.C.H.), Malawi-Liverpool-Wellcome Trust Clinical Research Programme (R.S.H., N. Kalata, K.G., M.P., J.E.) and the College of Medicine, University of Malawi (R.S.H., N. Kalata, K.G., M.P., J.E., J.J.O.), Blantyre, and Dignitas International, Zomba Central Hospital, Zomba (A.K.C., P.B., D.L., J.J.O.) - all in Malawi; University of Dschang, Dschang (C. Kouanfack), Hôpital Central Yaoundé/Site Agence Nationale de Recherche sur le Sida (ANRS) Cameroun, Yaoundé (C. Kouanfack, S. Lontsi, J.-G.N., V.S.), and Douala General Hospital (E.T., Y.N.M.) and University of Douala (Y.N.M.), Douala - all in Cameroon; the Institute for Medical Research and Training (D.C., N.S., N. Karunaharan, P.B.), University Teaching Hospital (D.C., S. Lakhi, N.S., N. Karunaharan, P.B.), and the Department of Internal Medicine and Directorate of Research and Postgraduate Studies, Lusaka Apex Medical University (P.M.), Lusaka, Zambia; the National Institute for Medical Research, Muhimbili Medical Research Centre, Dar Es Salaam, Tanzania (S.M., S. Lesikari); Institut Pasteur, Molecular Mycology Unit (E.T., O.L.), and Paris Descartes University, Necker Pasteur Center for Infectious Diseases and Tropical Medicine, IHU Imagine, Assistance Publique-Hôpitaux de Paris (O.L.), Paris; the Division of Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto (A.K.C.); and the University of North Carolina, Chapel Hill (C.H., M.C.H.).

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http://dx.doi.org/10.1056/NEJMoa1710922DOI Listing
March 2018

Effects of concurrent exposure to antiretrovirals and cotrimoxazole prophylaxis among HIV-exposed, uninfected infants.

AIDS 2017 11;31(18):2455-2463

aCenters for Disease Control and Prevention, Atlanta, Georgia, USA bDepartment of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Johannesburg, South Africa cUniversity of North Carolina, Chapel Hill, North Carolina, USA dUNC Project, Lilongwe, Malawi.

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http://dx.doi.org/10.1097/QAD.0000000000001641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059368PMC
November 2017

HIV-infected Children in Malawi Have Decreased Performance on the 6-minute Walk Test With Preserved Cardiac Mechanics Regardless of Antiretroviral Treatment Status.

Pediatr Infect Dis J 2017 07;36(7):659-664

From the *Department of pediatric cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, Texas; †Department of Infectious Disease, University of North Carolina Project, Lilongwe, Malawi, Africa; ‡Dan L Duncan Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, Texas; §Department of Infectious Disease, University of North Carolina, Chapel Hill, North Carolina; ¶Department of Pediatrics, Baylor College of Medicine Children's Clinical Center of Excellence, Lilongwe, Malawi, Africa; and ‖Department of Pediatric Cardiology, Children's National Medical Center, Washington, DC.

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http://dx.doi.org/10.1097/INF.0000000000001540DOI Listing
July 2017

Seek, test, treat: substance-using women in the HIV treatment cascade in South Africa.

Addict Sci Clin Pract 2017 04 26;12(1):12. Epub 2017 Apr 26.

Substance Use, Gender and Applied Research, RTI International, 3040 East Cornwallis Road, Research Triangle Park, NC, 27709-2194, USA.

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http://dx.doi.org/10.1186/s13722-017-0077-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405464PMC
April 2017

Maternal and Breastmilk Viral Load: Impacts of Adherence on Peripartum HIV Infections Averted-The Breastfeeding, Antiretrovirals, and Nutrition Study.

J Acquir Immune Defic Syndr 2016 Dec;73(5):572-580

*Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC; †Division of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC; ‡Currently, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA; §Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC; ‖Division of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Parktown, South Africa; ¶UNC Project, University of North Carolina, Lilongwe, Malawi; #Department of Microbiology and Immunology, School of Medicine, Center for AIDS Research, University of North Carolina, Chapel Hill, NC; **Division of Global Women's Health, Department of Obstetrics & Gynecology, Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC; and ††Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA.

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http://dx.doi.org/10.1097/QAI.0000000000001145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141681PMC
December 2016

The National Institutes of Health Fogarty International Center Global Health Scholars and Fellows Program: Collaborating Across Five Consortia to Strengthen Research Training.

Am J Trop Med Hyg 2016 09 5;95(3):728-34. Epub 2016 Jul 5.

Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.4269/ajtmh.16-0190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014285PMC
September 2016

Role of antibiotics in reducing childhood mortality in resource-poor settings.

AIDS 2016 05;30(8):1310-1

aUS Centers for Disease Control and Prevention, Atlanta, Georgia, USA bUniversity of Witwatersrand, Johannesburg, South Africa cUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001044DOI Listing
May 2016

Editorial Commentary: Cryptococcosis in AIDS: New Data but Questions Remain.

Clin Infect Dis 2016 Mar 12;62(5):588-9. Epub 2015 Nov 12.

UNICEF, New York, New York.

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http://dx.doi.org/10.1093/cid/civ939DOI Listing
March 2016

Toxicity of Amphotericin B Deoxycholate-Based Induction Therapy in Patients with HIV-Associated Cryptococcal Meningitis.

Antimicrob Agents Chemother 2015 Dec 8;59(12):7224-31. Epub 2015 Sep 8.

Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom Botswana-UPenn Partnership, Gaborone, Botswana Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1128/AAC.01698-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649151PMC
December 2015

Time of HIV diagnosis in infants after weaning from breast milk.

AIDS 2015 Sep;29(14):1897-8

aDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA bDepartment of Microbiology and Immunology cDivision of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665637PMC
September 2015

Delayed HIV detection among infants exposed to postnatal antiretroviral prophylaxis during breastfeeding.

AIDS 2015 Sep;29(15):1953-61

aDivision of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia bDepartment of Pediatrics, Johns Hopkins University, Baltimore, Maryland, USA cDepartment of Microbiology and Immunology, School of Medicine dDepartment of Biostatistics, Gillings School of Global Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA eUNC Project-Malawi, Lilongwe, Malawi fDivision of Epidemiology and Biostatistics, University of Witwatersrand, Johannesburg, South Africa gDivision of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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https://insights.ovid.com/crossref?an=00002030-201509240-000
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http://dx.doi.org/10.1097/QAD.0000000000000794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665628PMC
September 2015

Antiretroviral Treatment Is Associated With Iron Deficiency in HIV-Infected Malawian Women That Is Mitigated With Supplementation, but Is Not Associated With Infant Iron Deficiency During 24 Weeks of Exclusive Breastfeeding.

J Acquir Immune Defic Syndr 2015 Jul;69(3):319-28

*Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; †Department of Nutrition, University of Witwatersrand, Parktown, South Africa; ‡Faculty of Health Sciences,UNC Project, Lilongwe, Malawi; §Division of Reproductive Health, US Centers for Disease Control and Prevention, Atlanta, GA; and #US Department of Agriculture, Agricultural Research Service, Western Human Nutrition Research Center, Davis, CA.

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http://dx.doi.org/10.1097/QAI.0000000000000588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506710PMC
July 2015

Civil disobedience and physicians--protesting the blockade of Medicaid.

N Engl J Med 2014 Nov;371(21):1958-60

From the Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill.

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http://dx.doi.org/10.1056/NEJMp1410288DOI Listing
November 2014

Adherence to extended postpartum antiretrovirals is associated with decreased breast milk HIV-1 transmission.

AIDS 2014 Nov;28(18):2739-49

aDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina bDivision of Infectious Diseases, Department of Medicine, School of Medicine, University of North Carolina cDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA dDivision of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Parktown, South Africa eUniversity of North Carolina, UNC Project, Lilongwe, Malawi fDepartment of Microbiology and Immunology, School of Medicine; Center for AIDS Research, University of North Carolina gGlobal Women's Health Division, Department of Obstetrics & Gynecology; Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, North Carolina hDivision of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

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https://insights.ovid.com/crossref?an=00002030-201411280-000
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http://dx.doi.org/10.1097/QAD.0000000000000492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397579PMC
November 2014

The biobehavioral Women's Health CoOp in Pretoria, South Africa: study protocol for a cluster-randomized design.

BMC Public Health 2014 Oct 15;14:1074. Epub 2014 Oct 15.

RTI International, 3040 E, Cornwallis Road, PO Box 12194, Research Triangle Park, NC 27709-2194, USA.

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http://dx.doi.org/10.1186/1471-2458-14-1074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287508PMC
October 2014

Clinical versus rapid molecular HIV diagnosis in hospitalized African infants: a randomized controlled trial simulating point-of-care infant testing.

J Acquir Immune Defic Syndr 2014 May;66(1):e23-30

*University of North Carolina Project, Lilongwe, Malawi; †Department of Pediatrics, Division of Pulmonology, Johns Hopkins School of Medicine, Baltimore, MD; ‡Department of Pediatrics, Baylor College of Medicine, Houston, TX; §Department of Pediatrics, Division of Infectious Diseases, University of Colorado, Aurora, CO; ‖Baylor College of Medicine Children's Foundation Malawi, Lilongwe, Malawi; and ¶Department of Medicine, Division of Infectious Diseases, School of Medicine, University of North Carolina, Chapel Hill, NC.

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http://dx.doi.org/10.1097/QAI.0000000000000080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345126PMC
May 2014

Plasma and breast-milk selenium in HIV-infected Malawian mothers are positively associated with infant selenium status but are not associated with maternal supplementation: results of the Breastfeeding, Antiretrovirals, and Nutrition study.

Am J Clin Nutr 2014 Apr 5;99(4):950-6. Epub 2014 Feb 5.

Carolina Population Center (VLF, MEB, EJD, and LSA), Departments of Nutrition (VLF, MEB, and LSA) and Biostatistics (EJD), and Division of Infectious Diseases, School of Medicine (AF and CMvdH), University of North Carolina, Chapel Hill, NC; the USDA-Agriculture Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND (GFC); the University of North Carolina Project, Lilongwe, Malawi (CSC, D Kayira, GT, and D Kamwendo); the Division of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Parktown, South Africa (CSC); and the US CDC, Atlanta, GA (APK and DJJ).

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http://dx.doi.org/10.3945/ajcn.113.073833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953887PMC
April 2014

Role of intestinal mucosal integrity in HIV transmission to infants through breast-feeding: the BAN study.

J Infect Dis 2013 Aug 17;208(4):653-61. Epub 2013 May 17.

Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.

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http://dx.doi.org/10.1093/infdis/jit221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719904PMC
August 2013

Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A.

Virology 2012 Nov 24;433(1):220-5. Epub 2012 Aug 24.

Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7290, USA.

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http://dx.doi.org/10.1016/j.virol.2012.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505605PMC
November 2012

New insights in the prevention, diagnosis, and treatment of cryptococcal meningitis.

Curr HIV/AIDS Rep 2012 Sep;9(3):267-77

Center for Infectious Diseases, 2nd Floor Bioinformatics, 130 Mason Farm Road, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s11904-012-0127-7DOI Listing
September 2012

Pregnancy and virologic response to antiretroviral therapy in South Africa.

PLoS One 2011 2;6(8):e22778. Epub 2011 Aug 2.

Department of Obstetrics and Gynecology, Duke Global Health Institute, Duke University, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022778PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149058PMC
December 2011

Tuberculosis and HIV: danse macabre.

AIDS 2010 Jul;24(12):1953-4

Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27607, USA.

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http://dx.doi.org/10.1097/QAD.0b013e32833c1db1DOI Listing
July 2010

Variability in drug metabolizing enzyme activity in HIV-infected patients.

Eur J Clin Pharmacol 2010 May 19;66(5):475-85. Epub 2010 Jan 19.

School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1007/s00228-009-0777-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855129PMC
May 2010

Evaluating nurses' implementation of an infant-feeding counseling protocol for HIV-infected mothers: The Ban Study in Lilongwe, Malawi.

Authors:
Yvonne Owens Ferguson Eugenia Eng Margaret Bentley Margarete Sandelowski Allan Steckler Elizabeth Randall-David Ellen G Piwoz Cynthia Zulu Charles Chasela Alice Soko Martin Tembo Francis Martinson Beth Carlton Tohill Yusuf Ahmed Peter Kazembe Denise J Jamieson Charles van der Horst Linda Adair Yusuf Ahmed Mounir Ait-Khaled Sandra Albrecht Shrikant Bangdiwala Ronald Bayer Margaret Bentley Brian Bramson Emily Bobrow Nicola Boyle Sal Butera Charles Chasela Charity Chavula Joseph Chimerang'ambe Maggie Chigwenembe Maria Chikasema Norah Chikhungu David Chilongozi Grace Chiudzu Lenesi Chome Anne Cole Amanda Corbett Amy Corneli Ann Duerr Henry Eliya Sascha Ellington Joseph Eron Sherry Farr Yvonne Owens Ferguson Susan Fiscus Shannon Galvin Laura Guay Chad Heilig Irving Hoffman Elizabeth Hooten Mina Hosseinipour Michael Hudgens Stacy Hurst Lisa Hyde Denise Jamieson George Joaki David Jones Zebrone Kacheche Esmie Kamanga Gift Kamanga Coxcilly Kampani Portia Kamthunzi Deborah Kamwendo Cecilia Kanyama Angela Kashuba Damson Kathyola Dumbani Kayira Peter Kazembe Rodney Knight Athena Kourtis Robert Krysiak Jacob Kumwenda Edde Loeliger Misheck Luhanga Victor Madhlopa Maganizo Majawa Alice Maida Cheryl Marcus Francis Martinson Navdeep Thoofer Chrissie Matika Douglas Mayers Isabel Mayuni Marita McDonough Joyce Meme Ceppie Merry Khama Mita Chimwemwe Mkomawanthu Gertrude Mndala Ibrahim Mndala Agnes Moses Albans Msika Wezi Msungama Beatrice Mtimuni Jane Muita Noel Mumba Bonface Musis Charles Mwansambo Gerald Mwapasa Jacqueline Nkhoma Richard Pendame Ellen Piwoz Byron Raines Zane Ramdas John Rublein Mairin Ryan Ian Sanne Christopher Sellers Diane Shugars Dorothy Sichali Wendy Snowden Alice Soko Allison Spensley Jean-Marc Steens Gerald Tegha Martin Tembo Roshan Thomas Hsiao-Chuan Tien Beth Tohill Charles van der Horst Esther Waalberg Jeffrey Wiener Cathy Wilfert Patricia Wiyo Onnocent Zgambo Chifundo Zimba

AIDS Educ Prev 2009 Apr;21(2):141-55

University of North Carolina at Chapel Hill, USA.

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http://dx.doi.org/10.1521/aeap.2009.21.2.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903193PMC
April 2009

Factors associated with early study discontinuation in AACTG studies, DACS 200.

Contemp Clin Trials 2007 Sep 27;28(5):583-92. Epub 2007 Feb 27.

Harvard School of Public Health, 651 Huntington Ave., Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cct.2007.02.002DOI Listing
September 2007

Microalbuminuria in HIV infection.

AIDS 2007 May;21(8):1003-9

Duke University Medical Center, Department of Medicine, Division of Nephrology, Durham, North Carolina, USA.

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http://dx.doi.org/10.1097/QAD.0b013e3280d3587fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189480PMC
May 2007

Survival in women exposed to single-dose nevirapine for prevention of mother-to-child transmission of HIV: a stochastic model.

J Infect Dis 2007 Mar 7;195(6):837-46. Epub 2007 Feb 7.

Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1086/511276DOI Listing
March 2007

A reduced frequency visit schedule underreports adverse events that resulted in dose modifications or treatment discontinuations in HIV/AIDS clinical trials: ACTG DACS 207.

Contemp Clin Trials 2006 Jun 20;27(3):287-94. Epub 2006 Mar 20.

Harvard School of Public Health, Center for Biostatistics in AIDS Research, 651 Huntington Avenue, FXB Building, 5th Floor, Boston, MA, 02115-6009, USA.

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http://dx.doi.org/10.1016/j.cct.2006.02.001DOI Listing
June 2006

Low absolute neutrophil counts in African infants.

J Int Assoc Physicians AIDS Care (Chic) 2005 Jul;4(3):73-6

Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 20241, USA.

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http://dx.doi.org/10.1177/1545109705282591DOI Listing
July 2005

Cytomegalovirus viremia, mortality, and end-organ disease among patients with AIDS receiving potent antiretroviral therapies.

J Acquir Immune Defic Syndr 2005 Apr;38(5):538-44

Division of Infectious Diseases, The University of North Carolina, Chapel Hill, NC 27599, USA.

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April 2005

A randomized study of emtricitabine and lamivudine in stably suppressed patients with HIV.

AIDS 2004 Nov;18(17):2269-76

Division of Infectious Disease, University of Colorado Health Sciences Center, Denver, Colorado, USA.

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http://dx.doi.org/10.1097/00002030-200411190-00007DOI Listing
November 2004

Research as a path to wide-scale implementation of antiretroviral therapy in Africa.

J HIV Ther 2004 Sep;9(3):65-8

University of the Witwatersrand, Clinical HIV Research Unit and University of the Witwatersrand, Thembaletu Clinic, Helen Joseph Hospital, Perth Avenue, Westdene, Gauteng, South Africa.

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September 2004