Publications by authors named "Charles Sawyers"

100Publications

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer.

Cancer Cell 2020 Oct 3;38(4):534-550.e9. Epub 2020 Sep 3.

Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.08.003DOI Listing
October 2020

Modulation of androgen receptor DNA binding activity through direct interaction with the ETS transcription factor ERG.

Proc Natl Acad Sci U S A 2020 04 27;117(15):8584-8592. Epub 2020 Mar 27.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1922159117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165421PMC
April 2020

Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation.

Cancer Cell 2020 04 26;37(4):584-598.e11. Epub 2020 Mar 26.

Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA; Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292228PMC
April 2020

Publisher Correction: Lineage plasticity in cancer: a shared pathway of therapeutic resistance.

Nat Rev Clin Oncol 2020 Jun;17(6):382

Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41571-020-0355-5DOI Listing
June 2020

Lineage plasticity in cancer: a shared pathway of therapeutic resistance.

Nat Rev Clin Oncol 2020 06 9;17(6):360-371. Epub 2020 Mar 9.

Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41571-020-0340-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397755PMC
June 2020

Prostate Organoid Cultures as Tools to Translate Genotypes and Mutational Profiles to Pharmacological Responses.

J Vis Exp 2019 10 24(152). Epub 2019 Oct 24.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center;

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http://dx.doi.org/10.3791/60346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318111PMC
October 2019

Herceptin: A First Assault on Oncogenes that Launched a Revolution.

Cell 2019 Sep 10;179(1):8-12. Epub 2019 Sep 10.

Howard Hughes Medical Institute, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.08.027DOI Listing
September 2019

American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond-Lessons Learned and Member Institutions' Perspectives.

JCO Clin Cancer Inform 2018 12;2:1-14

Christine M. Micheel, Michele L. LeNoue-Newton, and Mia A. Levy, Vanderbilt University Medical Center, Nashville, TN; Shawn M. Sweeney, American Association for Cancer Research, Philadelphia, PA; Fabrice André, Institut Gustave Roussy, Villejuif, France; Philippe L. Bedard, University of Toronto, Toronto, Ontario, Canada; Justin Guinney, Sage Bionetworks, Seattle, WA; Gerrit A. Meijer, Netherlands Cancer Institute, Amsterdam, the Netherlands; Barrett J. Rollins, Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA; Charles L. Sawyers and Nikolaus Schultz, Memorial Sloan Kettering Cancer Center, New York, NY; Charles L. Sawyers, Howard Hughes Medical Institute, Chevy Chase, MD; Victor E. Velculescu, Johns Hopkins University School of Medicine, Baltimore, MD; and Kenna R. Mills Shaw, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1200/CCI.17.00083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873906PMC
December 2018

Strategies to Identify and Target Cells of Origin in Prostate Cancer.

J Natl Cancer Inst 2019 03;111(3):221-223

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, USA.

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https://academic.oup.com/jnci/advance-article/doi/10.1093/jn
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http://dx.doi.org/10.1093/jnci/djy146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410934PMC
March 2019

Challenges in validating candidate therapeutic targets in cancer.

Elife 2018 02 8;7. Epub 2018 Feb 8.

Salk Institute for Biological Studies, La Jolla, United States.

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https://elifesciences.org/articles/32402
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http://dx.doi.org/10.7554/eLife.32402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805407PMC
February 2018

Targeting DNA Repair in Prostate Cancer.

J Clin Oncol 2018 04 25;36(10):1017-1019. Epub 2018 Jan 25.

Wassim Abida, Memorial Sloan Kettering Cancer Center, New York, NY; and Charles L. Sawyers, Memorial Sloan Kettering Cancer Center, New York, NY; and Howard Hughes Medical Institute, Chevy Chase, MD.

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http://dx.doi.org/10.1200/JCO.2017.76.6592DOI Listing
April 2018

Dorcas Cummings Lecture.

Authors:
Charles Sawyers

Cold Spring Harb Symp Quant Biol 2016 9;81:291-295. Epub 2017 Mar 9.

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http://dx.doi.org/10.1101/sqb.2016.81.031971DOI Listing
July 2018

Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome.

Cell Rep 2016 12;17(10):2596-2606

Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Urology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367888PMC
December 2016

A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.

PLoS One 2016 18;11(8):e0161084. Epub 2016 Aug 18.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, 10065, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161084PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990297PMC
July 2017

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.

N Engl J Med 2016 Aug 6;375(5):443-53. Epub 2016 Jul 6.

From the University of Washington (C.C.P., M. Beightol, C.M., B.N., H.H.C., B.M., T.W., S. Casadei, P.S.N.) and Fred Hutchinson Cancer Research Center (N.D.S., R.G., P.S.N.) - both in Seattle; the Institute of Cancer Research and Royal Marsden Hospital, London (J.M., S. Carreira, R.E., J.B.); Memorial Sloan Kettering Cancer Center (M.F.W., W.A., M. Berger, L.Z., A.Z., J. Vijai, H.I.S., C.S., N.S., P.W.K., D.S., M.R., K.O.), Weill Cornell Medical College (H.B., O.E., M.A.R.), and the Prostate Cancer Clinical Trials Consortium (J. Vinson, J.F.) - all in New York; the University of Michigan, Ann Arbor (D.R., R.L., M.H., A.C.); Howard Hughes Medical Institute, Chevy Chase, MD (A.C., C.S.); and Dana-Farber Cancer Institute, Boston (A.G., L.G., M.-E.T., S.A., G.C.H., E.M.V.A.).

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http://dx.doi.org/10.1056/NEJMoa1603144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986616PMC
August 2016

Organoid culture systems for prostate epithelial and cancer tissue.

Nat Protoc 2016 Feb 21;11(2):347-58. Epub 2016 Jan 21.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/nprot.2016.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793718PMC
February 2016

Applying ⁸⁹Zr-Transferrin To Study the Pharmacology of Inhibitors to BET Bromodomain Containing Proteins.

Mol Pharm 2016 Feb 12;13(2):683-8. Epub 2016 Jan 12.

Department of Radiology and Biomedical Imaging, University of California San Francisco , 185 Berry Street, Lobby 6 Suite 350, San Francisco, California 94143, United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738321PMC
February 2016

Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer.

Nat Rev Cancer 2015 Dec 13;15(12):701-11. Epub 2015 Nov 13.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/nrc4016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771416PMC
December 2015

Identification of an oncogenic RAB protein.

Science 2015 Oct 3;350(6257):211-7. Epub 2015 Sep 3.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.

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http://sabatinilab.wi.mit.edu/pubs/2013/Science-2015-Wheeler
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http://www.sciencemag.org/cgi/doi/10.1126/science.aaa4903
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http://dx.doi.org/10.1126/science.aaa4903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600465PMC
October 2015

Integrative clinical genomics of advanced prostate cancer.

Cell 2015 May;161(5):1215-1228

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484602PMC
May 2015

Feedback suppression of PI3Kα signaling in PTEN-mutated tumors is relieved by selective inhibition of PI3Kβ.

Cancer Cell 2015 Jan 24;27(1):109-22. Epub 2014 Dec 24.

Molecular Pharmacology and Chemistry Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2014.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293347PMC
January 2015

Identifying actionable targets through integrative analyses of GEM model and human prostate cancer genomic profiling.

Mol Cancer Ther 2015 Jan 7;14(1):278-88. Epub 2014 Nov 7.

Human Oncology and Pathogenesis Oncology Program, Memorial Sloan-Kettering Cancer Center, New York, New York. Department of Surgery and Division of Urology, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://mct.aacrjournals.org/content/14/1/278.full.pdf
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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-14
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http://dx.doi.org/10.1158/1535-7163.MCT-14-0542-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297258PMC
January 2015

MAGI-2 scaffold protein is critical for kidney barrier function.

Proc Natl Acad Sci U S A 2014 Oct 30;111(41):14876-81. Epub 2014 Sep 30.

Human Oncology and Pathogenesis Program, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1417297111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4205655PMC
October 2014

Reliable and effective diagnostics are keys to accelerating personalized cancer medicine and transforming cancer care: a policy statement from the american association for cancer research.

Clin Cancer Res 2014 Oct 9;20(19):4978-81. Epub 2014 Sep 9.

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2295DOI Listing
October 2014

Organoid cultures derived from patients with advanced prostate cancer.

Cell 2014 Sep 4;159(1):176-187. Epub 2014 Sep 4.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College and New York-Presbyterian Hospital, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237931PMC
September 2014

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Cell 2014 Sep 4;159(1):163-175. Epub 2014 Sep 4.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772677PMC
September 2014

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.

Genes Dev 2014 Aug;28(16):1800-14

Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA; Cell and Developmental Biology Program, Weill Graduate School of Medical Sciences, Cornell University, New York, New York 10065, USA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA;

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http://dx.doi.org/10.1101/gad.244368.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197965PMC
August 2014

SPOP mutations in prostate cancer across demographically diverse patient cohorts.

Neoplasia 2014 Jan;16(1):14-20

Department of Pathology and Laboratory Medicine, Institute of Precision Medicine, Weill Medical College of Cornell University, New York, NY ; Department of Urology, Weill Medical College of Cornell University, New York, NY ; Institute for Precision Medicine, Weill Medical College of Cornell University, New York, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924544PMC
http://dx.doi.org/10.1593/neo.131704DOI Listing
January 2014

Glucocorticoid receptor confers resistance to antiandrogens by bypassing androgen receptor blockade.

Cell 2013 Dec;155(6):1309-22

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cell.2013.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932525PMC
December 2013

"N of 1" case reports in the era of whole-genome sequencing.

J Clin Invest 2013 Nov 25;123(11):4568-70. Epub 2013 Oct 25.

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http://dx.doi.org/10.1172/JCI70935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809802PMC
November 2013

Androgen receptor signaling regulates DNA repair in prostate cancers.

Cancer Discov 2013 Nov 11;3(11):1245-53. Epub 2013 Sep 11.

1Human Oncology Pathogenesis Program, 2Developmental Biology Program, and 3Immunology Program; Departments of 4Radiation Oncology, 5Medicine, 6Surgery, and 7Pathology; 8Molecular Cytology Core Facility, Memorial Sloan-Kettering Cancer Center; 9Department of Genetics, Albert Einstein College of Medicine, New York, New York; 10Department of Genetics; and 11Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888815PMC
November 2013

Phase I study of ARN-509, a novel antiandrogen, in the treatment of castration-resistant prostate cancer.

J Clin Oncol 2013 Oct 3;31(28):3525-30. Epub 2013 Sep 3.

Dana E. Rathkopf, Michael J. Morris, Josef J. Fox, Daniel C. Danila, Susan F. Slovin, Mithat Gönen, Martin Fleisher, Steven M. Larson, Charles L. Sawyers, and Howard I. Scher, Memorial Sloan-Kettering Cancer Center; Dana E. Rathkopf, Michael J. Morris, Josef J. Fox, Daniel C. Danila, Susan F. Slovin, Steven M. Larson, and Howard I. Scher, Weill Cornell Medical College, New York, NY; Jeffrey H. Hager, Peter J. Rix, Edna Chow Maneval, and Isan Chen, Aragon Pharmaceuticals, San Diego, CA; and Charles L. Sawyers, Howard Hughes Medical Institute, Chevy Chase, MD.

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http://dx.doi.org/10.1200/JCO.2013.50.1684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782148PMC
October 2013

Perspective: combined forces.

Nature 2013 Jun;498(7455):S7

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, USA.

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http://dx.doi.org/10.1038/498S7aDOI Listing
June 2013

Overcoming mutation-based resistance to antiandrogens with rational drug design.

Elife 2013 Apr 9;2:e00499. Epub 2013 Apr 9.

Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences , Memorial Sloan-Kettering Cancer Center , New York , United States ; Human Oncology and Pathogenesis Program , Memorial Sloan-Kettering Cancer Center , New York , United States.

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https://elifesciences.org/articles/00499
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http://dx.doi.org/10.7554/eLife.00499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622181PMC
April 2013

β4 Integrin signaling induces expansion of prostate tumor progenitors.

J Clin Invest 2013 Feb 25;123(2):682-99. Epub 2013 Jan 25.

Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, New York, USA.

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http://www.jci.org/articles/view/60720
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http://dx.doi.org/10.1172/JCI60720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561800PMC
February 2013

The 2011 Gordon Wilson Lecture: overcoming resistance to targeted cancer drugs.

Trans Am Clin Climatol Assoc 2012 ;123:114-23; discussion 123-5

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, Howard Hughes Medical Institute, 1275 York Avenue, New York, NY 10065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540597PMC
July 2013

Imaging tumor burden in the brain with 89Zr-transferrin.

J Nucl Med 2013 Jan 12;54(1):90-5. Epub 2012 Dec 12.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.2967/jnumed.112.109777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747823PMC
January 2013

Cancer drug development. Preface.

Curr Top Microbiol Immunol 2012 ;355:v-vi

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August 2014

Annotating MYC status with 89Zr-transferrin imaging.

Nat Med 2012 Oct 23;18(10):1586-91. Epub 2012 Sep 23.

Radiochemistry Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://www.nature.com/articles/nm.2935
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http://dx.doi.org/10.1038/nm.2935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3521603PMC
October 2012

Traversing the genomic landscape of prostate cancer from diagnosis to death.

Nat Genet 2012 May 29;44(6):613-4. Epub 2012 May 29.

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http://www.nature.com/articles/ng.2301
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http://dx.doi.org/10.1038/ng.2301DOI Listing
May 2012

Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen.

Cancer Discov 2012 Apr 31;2(4):320-7. Epub 2012 Mar 31.

Department of Surgery, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351274PMC
April 2012

In cancer drug resistance, germline matters too.

Nat Med 2012 Apr 5;18(4):494-6. Epub 2012 Apr 5.

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http://www.nature.com/articles/nm.2725
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http://dx.doi.org/10.1038/nm.2725DOI Listing
April 2012

Converting cancer therapies into cures: lessons from infectious diseases.

Cell 2012 Mar;148(6):1089-98

Infectious Diseases Service and Immunology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cell.2012.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465702PMC
March 2012

Fitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemia.

PLoS One 2011 28;6(11):e27682. Epub 2011 Nov 28.

Program for Industrial and Systems Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027682PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225363PMC
April 2012

Visualization of the interstitial cells of cajal (ICC) network in mice.

J Vis Exp 2011 Jul 27(53). Epub 2011 Jul 27.

Department of Medicine, Memorial Sloan Kettering Cancer Center.

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http://dx.doi.org/10.3791/2802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197437PMC
July 2011

Noninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigen.

Proc Natl Acad Sci U S A 2011 Jun 23;108(23):9578-82. Epub 2011 May 23.

Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1073/pnas.1106383108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111331PMC
June 2011