Charles R Mackay

Charles R Mackay

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Charles R Mackay

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Deficiency of Prebiotic Fibre and Insufficient Signalling Through Gut Metabolite Sensing Receptors Leads to Cardiovascular Disease.

Circulation 2020 Feb 25. Epub 2020 Feb 25.

Heart Failure Research Group, Baker Heart and Diabetes Institute, Melbourne, Australia; Hypertension Research Laboratory, School of Biological Sciences, Faculty of Science, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.043081DOI Listing
February 2020

Dysfunctional microbiota with reduced capacity to produce butyrate as a basis for allergic diseases.

J Allergy Clin Immunol 2019 Dec 22;144(6):1513-1515. Epub 2019 Oct 22.

Department of Microbiology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia; Laboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.10.009DOI Listing
December 2019

Guidelines for Transparency on Gut Microbiome Studies in Essential and Experimental Hypertension.

Hypertension 2019 Dec 4;74(6):1279-1293. Epub 2019 Nov 4.

Infection and Immunity Program, Monash Biomedicine Discovery Institute (C.R.M.), Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13079DOI Listing
December 2019

Gαs-coupled GPCRs GPR65 and GPR174. Downers for immune responses.

Immunol Cell Biol 2018 04 14;96(4):341-343. Epub 2018 Mar 14.

Infection and Immunity Program, Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.

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http://dx.doi.org/10.1111/imcb.12027DOI Listing
April 2018

C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis.

Kidney Int 2018 03 12;93(3):615-625. Epub 2017 Dec 12.

Centre for Inflammatory Diseases, Monash University Department of Medicine, Clayton, Victoria, Australia; Department of Nephrology, Monash Health, Clayton, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.09.018DOI Listing
March 2018

Beyond gut feelings: how the gut microbiota regulates blood pressure.

Nat Rev Cardiol 2018 01 24;15(1):20-32. Epub 2017 Aug 24.

Heart Failure Research Group, Baker Heart and Diabetes Institute, 75 Commercial Road, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1038/nrcardio.2017.120DOI Listing
January 2018

A fully humanized IgG-like bispecific antibody for effective dual targeting of CXCR3 and CCR6.

PLoS One 2017 5;12(9):e0184278. Epub 2017 Sep 5.

Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184278PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584921PMC
October 2017

The nutrition-gut microbiome-physiology axis and allergic diseases.

Immunol Rev 2017 07;278(1):277-295

Infection and Immunity Program, Department of Biochemistry, Biomedicine Discovery Institute, Monash University, Clayton, Vic., Australia.

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http://dx.doi.org/10.1111/imr.12556DOI Listing
July 2017

c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses.

Cell Rep 2017 04;19(3):461-470

Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia; Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.03.060DOI Listing
April 2017

Metabolite-Sensing G Protein-Coupled Receptors-Facilitators of Diet-Related Immune Regulation.

Annu Rev Immunol 2017 04;35:371-402

Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia; email: , , ,

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http://dx.doi.org/10.1146/annurev-immunol-051116-052235DOI Listing
April 2017

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice.

Circulation 2017 Mar 7;135(10):964-977. Epub 2016 Dec 7.

From Heart Failure Research Group (F.Z.M., E.N., P.-Y.C., D.H., A.F., N.W.R., D.M.K.) and Human Epigenetics Group (M.Z., A.E.-O.), Baker Heart and Diabetes Institute, Melbourne, Australia; Central Clinical School, Faculty of Medicine Nursing and Health Sciences (F.Z.M., A.E.-O., D.M.K.), Infection and Immunity Program, Monash Biomedicine Discovery Institute (J.K.T., C.R.M.), Department of Biochemistry and Molecular Biology (J.K.T., S.K., C.R.M.), and Department of Physiology (N.W.R.), Monash University, Melbourne, Australia; Department of Pathology, University of Melbourne, Australia (A.E.-O.); and Institute the Heart Centre, Alfred Hospital, Melbourne, Australia (D.M.K.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024545DOI Listing
March 2017

Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety.

Mol Metab 2017 01 4;6(1):48-60. Epub 2016 Nov 4.

Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, W12 0NN, UK; Division of Diabetes and Nutritional Sciences, King's College London, London, SE1 9RT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220466PMC
January 2017

Avenues to autoimmune arthritis triggered by diverse remote inflammatory challenges.

J Autoimmun 2016 09 12;73:120-9. Epub 2016 Jul 12.

Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, 3800 VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.06.018DOI Listing
September 2016

G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation.

PLoS One 2016;11(9):e0163750. Epub 2016 Sep 22.

Centre for Inflammatory Diseases, Department of Medicine, School of Clinical Sciences, Monash University, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033414PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163750PLOS
September 2016

Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk.

Immunity 2016 06 7;44(6):1392-405. Epub 2016 Jun 7.

The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936415PMC
June 2016

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

Cell Rep 2016 06;15(12):2809-24

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia; Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia; Department of Physiology, Faculty of Medicine, The University of Sydney, Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.047DOI Listing
June 2016

Dietary metabolites and the gut microbiota: an alternative approach to control inflammatory and autoimmune diseases.

Clin Transl Immunology 2016 May 13;5(5):e82. Epub 2016 May 13.

Department of Biochemistry and Molecular Biology, Monash University , Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/cti.2016.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910123PMC
May 2016

GPR43 - A Prototypic Metabolite Sensor Linking Metabolic and Inflammatory Diseases.

Trends Endocrinol Metab 2015 Oct;26(10):511-512

Department of Immunology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Wellington Road, Clayton, Victoria 3800, Australia; Charles Perkins Centre, The University of Sydney, NSW 2006, Australia; School of Medical Sciences, The University of Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2015.07.009DOI Listing
October 2015

Delayed consent: will there be a shift in approach for US primary percutaneous coronary intervention trials?

Lancet 2015 Aug 7;386(9994):714-6. Epub 2015 May 7.

MedStar Washington Hospital Center, Washington, DC, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(15)60077-0DOI Listing
August 2015

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.

Mol Endocrinol 2015 Jul 15;29(7):1055-66. Epub 2015 Jun 15.

Division of Endocrinology, Metabolism, and Molecular Medicine (M.P., S.R.V., M.F., B.T.L.), Northwestern University, Chicago, Illinois 60611; Kovler Diabetes Center (B.W.), The University of Chicago, Chicago, Illinois 60637; Monash University (C.R.M.), Clayton, Victoria 3800, Australia; Montreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, and Department of Medicine (T.A., V.P.), University of Montreal, Quebec, H2X 0A9 Canada; Multispan (H.M.), Hayward, California 94545; Department of Pediatrics and the Herman B Wells Center for Pediatric Research (R.G.M.), Indiana University School of Medicine, Indianapolis, Indiana 4602; Department of Biochemistry and Molecular Biology (R.G.M.), Indiana University School of Medicine, Indianapolis, Indiana 46202; Department of Medicine (R.G.M.), Indiana University School of Medicine, Indianapolis, Indiana 46202; Department of Pharmaceutical Sciences (A.G.), Midwestern University, Downers Grove, Illinois 60515; and Jesse Brown Veterans Affairs Medical Center (B.T.L.), Chicago, Illinois 60612.

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http://dx.doi.org/10.1210/me.2015-1007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484778PMC
July 2015

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites.

Nat Commun 2015 Jun 23;6:7320. Epub 2015 Jun 23.

1] Department of Immunology, Monash University, Clayton, Victoria 3800, Australia [2] Charles Perkins Centre, Sydney University Medical School, University of Sydney, Sydney, New South Wales 2006, Australia.

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http://dx.doi.org/10.1038/ncomms8320DOI Listing
June 2015

CXCR3⁺CCR5⁺ T cells and autoimmune diseases: guilty as charged?

Authors:
Charles R Mackay

J Clin Invest 2014 Sep 2;124(9):3682-4. Epub 2014 Sep 2.

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http://dx.doi.org/10.1172/JCI77837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151222PMC
September 2014

Real-time interactive two-photon photoconversion of recirculating lymphocytes for discontinuous cell tracking in live adult mice.

J Biophotonics 2014 Jun 26;7(6):425-33. Epub 2012 Nov 26.

Immunological Diseases Division, Garvan Institute of Medical Research, Sydney, Australia; St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1002/jbio.201200175DOI Listing
June 2014

Diet, metabolites, and "western-lifestyle" inflammatory diseases.

Immunity 2014 Jun;40(6):833-42

Department of Immunology, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.05.014DOI Listing
June 2014

The role of short-chain fatty acids in health and disease.

Adv Immunol 2014 ;121:91-119

Department of Immunology, Monash University, Clayton, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-800100-4.00003-9DOI Listing
May 2014

BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice.

Eur J Immunol 2014 Apr 16;44(4):983-93. Epub 2014 Feb 16.

Immunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; Centre of Immunology and Inflammation, School of Biomedical Sciences, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1002/eji.201344186DOI Listing
April 2014

Chlamydia muridarum lung infection in infants alters hematopoietic cells to promote allergic airway disease in mice.

PLoS One 2012 1;7(8):e42588. Epub 2012 Aug 1.

Centre for Asthma and Respiratory Disease, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle and Hunter Medical Research Institute, Callaghan, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042588PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411632PMC
February 2013

B-cell cross-presentation of autologous antigen precipitates diabetes.

Diabetes 2012 Nov 24;61(11):2893-905. Epub 2012 Jul 24.

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.2337/db12-0006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478535PMC
November 2012

Protection against Nippostrongylus brasiliensis infection in mice is independent of GM-CSF.

Immunol Cell Biol 2012 May 16;90(5):553-8. Epub 2011 Aug 16.

Immunology Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1038/icb.2011.69DOI Listing
May 2012

IL-21 enhances the potential of human γδ T cells to provide B-cell help.

Eur J Immunol 2012 Jan 12;42(1):110-9. Epub 2011 Dec 12.

Department of Infection, Immunity and Biochemistry, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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http://doi.wiley.com/10.1002/eji.201142017
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http://dx.doi.org/10.1002/eji.201142017DOI Listing
January 2012

Specific expression of GPR56 by human cytotoxic lymphocytes.

J Leukoc Biol 2011 Oct 1;90(4):735-40. Epub 2011 Jul 1.

Department of Microbiology and Immunology, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan.

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http://dx.doi.org/10.1189/jlb.0211092DOI Listing
October 2011

CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses.

J Immunol 2011 May 6;186(10):5556-68. Epub 2011 Apr 6.

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://www.jimmunol.org/content/186/10/5556.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1002828
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1002828DOI Listing
May 2011

Commensal flora and the regulation of inflammatory and autoimmune responses.

Semin Immunol 2011 Apr 2;23(2):139-45. Epub 2011 Feb 2.

Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.smim.2011.01.011DOI Listing
April 2011

Diet, gut microbiota and immune responses.

Nat Immunol 2011 Jan;12(1):5-9

Garvan Institute of Medical Research, and the Cooperative Research Centre for Asthma and Airways, Sydney, Australia.

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http://dx.doi.org/10.1038/ni0111-5DOI Listing
January 2011

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

J Biol Chem 2010 Mar 31;285(10):7633-44. Epub 2009 Dec 31.

Pulmonary Division, Department of Pediatrics, Children's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1074/jbc.M109.092106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844210PMC
March 2010

Lineage specification and heterogeneity of T follicular helper cells.

Curr Opin Immunol 2009 Dec 5;21(6):619-25. Epub 2009 Nov 5.

Immunology and Inflammation, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.coi.2009.09.013DOI Listing
December 2009

The functional plasticity of T cell subsets.

Nat Rev Immunol 2009 11 7;9(11):811-6. Epub 2009 Oct 7.

University of California, San Francisco Diabetes Center and Department of Medicine, University of California, San Francisco 513 Parnassus Avenue, Box 0540-HSW 1114, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/nri2654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075537PMC
November 2009

Ethical considerations of live case transmissions.

Authors:
Charles R Mackay

JACC Cardiovasc Interv 2009 Sep;2(9):892-3

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http://dx.doi.org/10.1016/j.jcin.2009.07.004DOI Listing
September 2009

Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses.

Immunity 2009 Aug 16;31(2):259-69. Epub 2009 Jul 16.

Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.immuni.2009.06.016DOI Listing
August 2009

Moving targets: cell migration inhibitors as new anti-inflammatory therapies.

Authors:
Charles R Mackay

Nat Immunol 2008 Sep;9(9):988-98

Garvan Institute for Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/ni.f.210DOI Listing
September 2008

A fundamental role for interleukin-21 in the generation of T follicular helper cells.

Immunity 2008 Jul 3;29(1):127-37. Epub 2008 Jul 3.

Department of Immunology, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130800274
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http://dx.doi.org/10.1016/j.immuni.2008.06.001DOI Listing
July 2008

T follicular helper (TFH) cells in normal and dysregulated immune responses.

Annu Rev Immunol 2008 ;26:741-66

Immunology and Inflammation Research Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1146/annurev.immunol.26.021607.090344DOI Listing
June 2008

Functional roles for C5a receptors in sepsis.

Nat Med 2008 May 4;14(5):551-7. Epub 2008 May 4.

Department of Pathology, University of Michigan Medical School, 1301 Catherine Road, Ann Arbor, Michigan 48109, USA.

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http://www.nature.com/doifinder/10.1038/nm1753
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http://dx.doi.org/10.1038/nm1753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2753858PMC
May 2008

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2.

Immunol Cell Biol 2008 Feb 29;86(2):153-60. Epub 2008 Jan 29.

Immunology and Inflammation Department, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1038/sj.icb.7100166DOI Listing
February 2008

Granulocyte-macrophage colony-stimulating factor is required for bronchial eosinophilia in a murine model of allergic airway inflammation.

J Immunol 2008 Feb;180(4):2600-7

Immunology and Inflammation Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.4049/jimmunol.180.4.2600DOI Listing
February 2008

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.

Proc Natl Acad Sci U S A 2007 Sep 5;104(37):14759-64. Epub 2007 Sep 5.

Department of Immunology and Inflammation, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1073/pnas.0702229104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976222PMC
September 2007

BAFF and MyD88 signals promote a lupuslike disease independent of T cells.

J Exp Med 2007 Aug 30;204(8):1959-71. Epub 2007 Jul 30.

Autoimmunity Research Unit, The Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1084/jem.20062567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118661PMC
August 2007

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses.

Nat Rev Drug Discov 2007 May;6(5):391-403

Immunology and Inflammation Research Program, The Garvan Institute, Darlinghurst, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1038/nrd2289DOI Listing
May 2007

Targeting BAFF: immunomodulation for autoimmune diseases and lymphomas.

Pharmacol Ther 2006 Dec 24;112(3):774-86. Epub 2006 Jul 24.

The Immunology and Inflammation Research Program, The Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.pharmthera.2006.06.002DOI Listing
December 2006

Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2.

J Immunol 2006 Dec;177(11):7794-801

Immunology and Inflammation Research Program, Garvan Institute for Medical Research, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.4049/jimmunol.177.11.7794DOI Listing
December 2006

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies.

Nat Biotechnol 2006 Oct 17;24(10):1279-84. Epub 2006 Sep 17.

Immunology and Inflammation Department, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, NSW 2010, Australia.

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http://www.nature.com/doifinder/10.1038/nbt1248
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http://dx.doi.org/10.1038/nbt1248DOI Listing
October 2006

A new role for CCR5 in innate immunity--binding to bacterial heat shock protein 70.

Eur J Immunol 2006 Sep;36(9):2293-5

Immunology and Inflammation Department, Garvan Institute of Medical Research, Darlinghurst, Australia.

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http://dx.doi.org/10.1002/eji.200636551DOI Listing
September 2006

The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation.

J Clin Invest 2006 Aug;116(8):2183-2192

Immunology and Inflammation Research Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1172/JCI24767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1501108PMC
August 2006

Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes.

J Allergy Clin Immunol 2006 Aug 21;118(2):496-503. Epub 2006 Jun 21.

Immunology and Inflammation Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney 2010, Australia.

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http://dx.doi.org/10.1016/j.jaci.2006.04.040DOI Listing
August 2006

Clues to asthma pathogenesis from microarray expression studies.

Pharmacol Ther 2006 Jan 3;109(1-2):284-94. Epub 2005 Oct 3.

Arthritis and Inflammation Research Program, Garvan Institute for Medical Research, Darlinghurst, Australia.

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http://dx.doi.org/10.1016/j.pharmthera.2005.08.009DOI Listing
January 2006

A fundamental bimodal role for neuropeptide Y1 receptor in the immune system.

J Exp Med 2005 Dec;202(11):1527-38

The Arthritis and Inflammation Research Program, The Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.1084/jem.20051971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213323PMC
December 2005

Follicular B helper T cells in antibody responses and autoimmunity.

Nat Rev Immunol 2005 Nov;5(11):853-65

Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University, Canberra 2601, Australia.

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http://www.nature.com/articles/nri1714
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http://dx.doi.org/10.1038/nri1714DOI Listing
November 2005

BAFF-R, the major B cell-activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders.

Hum Pathol 2005 Oct;36(10):1113-9

Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.humpath.2005.08.005DOI Listing
October 2005

The BAFF/APRIL system: life beyond B lymphocytes.

Mol Immunol 2005 May 8;42(7):763-72. Epub 2004 Dec 8.

Arthritis and Asthma Research Program, The Garvan Institute of Medical Reseach, 384 Victoria St, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.molimm.2004.06.041DOI Listing
May 2005

BAFF augments certain Th1-associated inflammatory responses.

J Immunol 2005 May;174(9):5537-44

Arthritis and Asthma Research Program, Garvan Institute of Medical Research, Sydney, Australia.

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http://dx.doi.org/10.4049/jimmunol.174.9.5537DOI Listing
May 2005

CCL3L1 dose and HIV-1 susceptibility.

Authors:
Charles R Mackay

Trends Mol Med 2005 May;11(5):203-6

Arthritis and Inflammation Research Program, The Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW 2010, Australia.

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http://dx.doi.org/10.1016/j.molmed.2005.03.003DOI Listing
May 2005

Chemoattractants and their receptors in homeostasis and inflammation.

Curr Opin Immunol 2004 Dec;16(6):724-31

Institute for Research in Biomedicine, Via Vincenzo Vela 6, CH-6500 Bellinzona, Switzerland.

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http://dx.doi.org/10.1016/j.coi.2004.09.012DOI Listing
December 2004

TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.

J Immunol 2004 Jan;172(2):812-22

Department of Arthritis and Inflammation, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia.

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http://dx.doi.org/10.4049/jimmunol.172.2.812DOI Listing
January 2004

New avenues for anti-inflammatory therapy.

Authors:
Charles R Mackay

Nat Med 2002 Feb;8(2):117-8

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http://dx.doi.org/10.1038/nm0202-117DOI Listing
February 2002

Howard: paternity and Pandora's box.

Camb Q Healthc Ethics 1993 ;2(2):229-37

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September 1993

New study of the IRB system.

Authors:
Charles R Mackay

Kennedy Inst Ethics J 1992 Sep;2(3):283-4

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http://dx.doi.org/10.1353/ken.0.0245DOI Listing
September 1992