Charles McTiernan

Charles McTiernan

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Charles McTiernan

Charles McTiernan

Publications by authors named "Charles McTiernan"

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Maternal Obesity Affects Cardiac Remodeling and Recovery in Women with Peripartum Cardiomyopathy.

Am J Perinatol 2019 Apr 5;36(5):476-483. Epub 2018 Sep 5.

Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1055/s-0038-1669439DOI Listing
April 2019

Cardiac-specific deletion of GCN5L1 restricts recovery from ischemia-reperfusion injury.

J Mol Cell Cardiol 2019 Apr 15;129:69-78. Epub 2019 Feb 15.

Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States; Center for Metabolism and Mitochondrial Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486843PMC
April 2019

Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice.

J Mol Cell Cardiol 2019 Apr 26;129:174-178. Epub 2019 Feb 26.

Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA; Center for Metabolism and Mitochondrial Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486841PMC
April 2019

Chemokine receptor patterns and right heart failure in mechanical circulatory support.

J Heart Lung Transplant 2017 Jun 23;36(6):657-665. Epub 2016 Dec 23.

Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2016.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446283PMC
June 2017

Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy.

Am J Respir Crit Care Med 2017 03;195(5):596-606

1 Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute.

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http://dx.doi.org/10.1164/rccm.201606-1275CIDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363978PMC
March 2017

Reply: Better Studies Are Needed to Guide Treatment of Carbon Monoxide Poisoning.

Am J Respir Crit Care Med 2017 03;195(5):694-695

1 University of Pittsburgh Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201612-2463LEDOI Listing
March 2017

Improving Left Ventricular Myocardial Function After Myocardial Infarction: Is it in the BAG?

JACC Basic Transl Sci 2016 Dec 26;1(7):657-659. Epub 2016 Dec 26.

Heart, Lung, and Blood Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1016/j.jacbts.2016.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113519PMC
December 2016

Make Monocytes Classical Again! (Maybe).

J Card Fail 2016 05 24;22(5):366-7. Epub 2016 Mar 24.

Heart, Lung, and Blood Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Scaife 631a, 3550 Terrace St., Pittsburgh Pennsylvania 15213. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2016.03.009DOI Listing
May 2016

Novel Targets of Drug Treatment for Pulmonary Hypertension.

Am J Cardiovasc Drugs 2015 Aug;15(4):225-34

Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, E1226 BST 200 Lothrop Street, Pittsburgh, PA, 15213, USA,

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http://dx.doi.org/10.1007/s40256-015-0125-4DOI Listing
August 2015

Cardiac CD47 drives left ventricular heart failure through Ca2+-CaMKII-regulated induction of HDAC3.

J Am Heart Assoc 2014 Jun 10;3(3):e000670. Epub 2014 Jun 10.

Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA (M.S.S., M.Q., J.B., S.F.S., H.C.C., J.S.I.) Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA (M.S.S., H.C.C., J.S.I.).

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https://www.ahajournals.org/doi/10.1161/JAHA.113.000670
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http://dx.doi.org/10.1161/JAHA.113.000670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309049PMC
June 2014

Relaxin suppresses atrial fibrillation by reversing fibrosis and myocyte hypertrophy and increasing conduction velocity and sodium current in spontaneously hypertensive rat hearts.

Circ Res 2013 Jul 7;113(3):313-21. Epub 2013 Jun 7.

Department of Bioengineering, Medicine, University of Pittsburgh Medical Center Heart and Vascular Institute, and Developmental Biology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.113.301646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774019PMC
July 2013

Ultrasound-targeted microbubble destruction to deliver siRNA cancer therapy.

Cancer Res 2012 Dec 25;72(23):6191-9. Epub 2012 Sep 25.

Center for Ultrasound Molecular Imaging and Therapeutics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-11-4079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654825PMC
December 2012

Cardiac levels of NOS1AP RNA from right ventricular tissue recovered during lead extraction.

Heart Rhythm 2012 Mar 19;9(3):399-404. Epub 2011 Oct 19.

Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15475271110124
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http://dx.doi.org/10.1016/j.hrthm.2011.10.019DOI Listing
March 2012

Gene therapy of carcinoma using ultrasound-targeted microbubble destruction.

Ultrasound Med Biol 2011 Mar 21;37(3):393-402. Epub 2011 Jan 21.

Center for Ultrasound Molecular Imaging and Therapeutics, Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03015629100064
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http://dx.doi.org/10.1016/j.ultrasmedbio.2010.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111473PMC
March 2011

Fighting doxorubicin-induced cardiotoxicity with adiponectin.

Cardiovasc Res 2011 Feb 14;89(2):262-4. Epub 2010 Dec 14.

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http://dx.doi.org/10.1093/cvr/cvq393DOI Listing
February 2011

Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice.

Cardiovasc Res 2011 Jan 9;89(1):60-71. Epub 2010 Sep 9.

Cardiovascular Institute, University of Pittsburgh Medical Center, 1750 Bioscience Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/cvr/cvq288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002875PMC
January 2011

Adrenergic stimulation promotes T-wave alternans and arrhythmia inducibility in a TNF-alpha genetic mouse model of congestive heart failure.

Am J Physiol Heart Circ Physiol 2010 Feb 25;298(2):H440-50. Epub 2009 Nov 25.

Cardiovascular Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1152/ajpheart.01024.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822584PMC
February 2010

Extracellular superoxide dismutase regulates cardiac function and fibrosis.

J Mol Cell Cardiol 2009 Nov 18;47(5):730-42. Epub 2009 Aug 18.

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2009.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774793PMC
November 2009

Leptin signaling in the failing and mechanically unloaded human heart.

Circ Heart Fail 2009 Nov 19;2(6):676-83. Epub 2009 Aug 19.

Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.869909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780432PMC
November 2009

Leptin attenuates cardiac apoptosis after chronic ischaemic injury.

Cardiovasc Res 2009 Jul 20;83(2):313-24. Epub 2009 Feb 20.

Cardiovascular Institute, University of Pittsburgh Medical Center, 1750 Bioscience Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/cvr/cvp071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701718PMC
July 2009

Myocardial Fas and cytokine expression in end-stage heart failure: impact of LVAD support.

Clin Transl Sci 2008 Dec;1(3):245-8

Heart Failure/Transplantation Program, Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2008.00056.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350672PMC
December 2008

Caveolin-1 and caveolin-3 form heterooligomeric complexes in atrial cardiac myocytes that are required for doxorubicin-induced apoptosis.

Am J Physiol Heart Circ Physiol 2008 Jan 2;294(1):H392-401. Epub 2007 Nov 2.

Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://ajpheart.physiology.org/content/ajpheart/early/2007/1
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http://ajpheart.physiology.org/cgi/doi/10.1152/ajpheart.0103
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http://dx.doi.org/10.1152/ajpheart.01039.2007DOI Listing
January 2008

Leptin signalling reduces the severity of cardiac dysfunction and remodelling after chronic ischaemic injury.

Cardiovasc Res 2008 Jan 20;77(1):54-63. Epub 2007 Sep 20.

Cardiovascular Institute, University of Pittsburgh Medical Center, 1750 Bioscience Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvm023DOI Listing
January 2008

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

Mol Ther 2006 Jul 19;14(1):45-53. Epub 2006 May 19.

Department of Molecular Genetics & Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.ymthe.2006.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564441PMC
July 2006

Electrical remodeling of cardiac myocytes from mice with heart failure due to the overexpression of tumor necrosis factor-alpha.

Am J Physiol Heart Circ Physiol 2006 May 9;290(5):H2098-107. Epub 2005 Dec 9.

Department of Cell Biology and Physiology,University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00097.2005
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http://dx.doi.org/10.1152/ajpheart.00097.2005DOI Listing
May 2006

Differential expression of MMPs and TIMPs in moderate and severe heart failure in a transgenic model.

J Card Fail 2006 May;12(4):314-25

Cardiovascular Institute of the UPMC Health System, University of Pittsburgh, Pennsylvania, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S107191640600039
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http://dx.doi.org/10.1016/j.cardfail.2006.01.009DOI Listing
May 2006

Cardioprotection afforded by NF-kappaB ablation is associated with activation of Akt in mice overexpressing TNF-alpha.

Am J Physiol Heart Circ Physiol 2006 Feb 30;290(2):H590-8. Epub 2005 Sep 30.

Center for Translational Medicine, Dept. of Medicine, Jefferson Medical College, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1152/ajpheart.00379.2005DOI Listing
February 2006

Atrial contractile dysfunction, fibrosis, and arrhythmias in a mouse model of cardiomyopathy secondary to cardiac-specific overexpression of tumor necrosis factor-{alpha}.

Am J Physiol Heart Circ Physiol 2005 Oct 27;289(4):H1456-67. Epub 2005 May 27.

Cardiovascular Institute, University of Pittsburgh, 200 Lothrop St., Scaife S572, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1152/ajpheart.00733.2004DOI Listing
October 2005

Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transfer.

Circulation 2005 Oct 17;112(17):2650-9. Epub 2005 Oct 17.

Department of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.105.5
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http://dx.doi.org/10.1161/CIRCULATIONAHA.105.565598DOI Listing
October 2005

17 Beta-estradiol improves survival in male mice with cardiomyopathy induced by cardiac-specific tumor necrosis factor-alpha overexpression.

J Interferon Cytokine Res 2005 May;25(5):254-60

Department of Medicine, Jefferson Medical College, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1089/jir.2005.25.254DOI Listing
May 2005

Troponin I protein kinase C phosphorylation sites and ventricular function.

Cardiovasc Res 2004 Aug;63(2):245-55

Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.cardiores.2004.04.010DOI Listing
August 2004

Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.

Cardiovasc Res 2004 Jun;62(3):468-80

Cardiovascular Institute, University of Pittsburgh, 200 Lothrop Street, 1744.1 BST, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.cardiores.2004.02.006DOI Listing
June 2004

Is there any future for tumor necrosis factor antagonists in chronic heart failure?

Am J Cardiovasc Drugs 2004 ;4(1):11-9

Department of Medicine, Jefferson Medical College, Room 822, 1025 Walnut Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.2165/00129784-200404010-00002DOI Listing
April 2004

Gene expression profiling during the transition to failure in TNF-alpha over-expressing mice demonstrates the development of autoimmune myocarditis.

J Mol Cell Cardiol 2004 Apr;36(4):515-30

Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Suite 813 College Building, 1025 Walnut Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2004.01.008DOI Listing
April 2004

Morphological and functional changes in cardiac myocytes isolated from mice overexpressing TNF-alpha.

Am J Physiol Heart Circ Physiol 2003 Mar;284(3):H960-9

Cardiovascular Institute, University of Pittsburgh Health System, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1152/ajpheart.0718.2001DOI Listing
March 2003

The role of anticytokine therapy in heart failure: recent lessons from preclinical and clinical trials?

Med Clin North Am 2003 Mar;87(2):419-40

Department of Medicine, Thomas Jefferson University Medical College, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/s0025-7125(02)00189-xDOI Listing
March 2003

Calcium-dependent arrhythmias in transgenic mice with heart failure.

Am J Physiol Heart Circ Physiol 2003 Feb 17;284(2):H431-41. Epub 2002 Oct 17.

Cardiovascular Institute, University of Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1152/ajpheart.00431.2002DOI Listing
February 2003

Chronic exposure to interleukin 1beta induces a delayed and reversible alteration in excitation-contraction coupling of cultured cardiomyocytes.

Pflugers Arch 2002 Nov 13;445(2):246-56. Epub 2002 Sep 13.

Service de Réanimation Médicale, Pr Gibert, Institut de Cardiologie, Hopital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1007/s00424-002-0921-yDOI Listing
November 2002

MMP inhibition modulates TNF-alpha transgenic mouse phenotype early in the development of heart failure.

Am J Physiol Heart Circ Physiol 2002 Mar;282(3):H983-9

Cardiovascular Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00233.2001
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http://dx.doi.org/10.1152/ajpheart.00233.2001DOI Listing
March 2002