Charles Lu

Charles Lu

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Charles Lu

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The Effects of Liver Disease on Surgical Outcomes Following Adult Spinal Deformity Surgery.

World Neurosurg 2019 Jun 26. Epub 2019 Jun 26.

Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2019.06.137DOI Listing
June 2019

Matching Mitochondrial DNA Haplotypes for Circumventing Tissue-Specific Segregation Bias.

iScience 2019 Mar 5;13:371-379. Epub 2019 Mar 5.

Reproductive Medicine Center, Zhongshan Hospital, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai 200032, China. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426714PMC
March 2019

Metabolic dynamics in critically injured patients: a prospective cohort study integrated with 1H NMR metabolomics.

Asia Pac J Clin Nutr 2019 ;28(2):411-418

Department of Acute Care Surgery, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, China.

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http://dx.doi.org/10.6133/apjcn.201906_28(2).0024DOI Listing
January 2019

A Computerized Microelectrode Recording to Magnetic Resonance Imaging Mapping System for Subthalamic Nucleus Deep Brain Stimulation Surgery.

Oper Neurosurg (Hagerstown) 2018 06;14(6):661-667

Surgical Therapies Improving Movement Program, University of Michigan, Ann Arbor, Michigan.

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https://academic.oup.com/ons/article/14/6/661/4067764
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http://dx.doi.org/10.1093/ons/opx169DOI Listing
June 2018

Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 06 2;36(18):1813-1822. Epub 2018 Jan 2.

Zhongxing Liao, J. Jack Lee, Ritsuko Komaki, Daniel R. Gomez, Michael S. O'Reilly, Frank V. Fossella, George R. Blumenschein Jr, John V. Heymach, Ara A. Vaporciyan, Stephen G. Swisher, Pamela K. Allen, Stephen M. Hahn, James D. Cox, Charles S. Lu, and Radhe Mohan, The University of Texas MD Anderson Cancer Center, Houston, TX; and Noah Chan Choi and Thomas F. DeLaney, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.0720
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http://dx.doi.org/10.1200/JCO.2017.74.0720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008104PMC
June 2018

Shape memory response of porous NiTi shape memory alloys fabricated by selective laser melting.

J Mater Sci Mater Med 2018 Mar 21;29(4):40. Epub 2018 Mar 21.

Department of Mechanical Engineering, University of Kentucky, Lexington, KY, 40506-0503, USA.

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http://dx.doi.org/10.1007/s10856-018-6044-6DOI Listing
March 2018

Optimization of brain metabolism using metabolic-targeted therapeutic hypothermia can reduce mortality from traumatic brain injury.

J Trauma Acute Care Surg 2017 08;83(2):296-304

From the Department of Trauma Surgery (J.F., W.W., J.Z., S.L., H.J.), Department of Computational Mathematics and Biostatistics (W.W., J.Z., Z.Z., J.P., H.Y., C.D.L., H.J.), Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu; North Sichuan Medical College (W.W.), Nanchong, China; Department of Biochemistry (Z.Z.), Southwest Medical University, Luzhou; and Analytical and Testing Center (P.D.), Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1097/TA.0000000000001522DOI Listing
August 2017

Cohort study of oncologic emergencies in patients with head and neck cancer.

Head Neck 2017 06 27;39(6):1195-1204. Epub 2017 Mar 27.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/hed.24748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429871PMC
June 2017

Patterns of Treatment Failure in Anaplastic Thyroid Carcinoma.

Thyroid 2017 05 16;27(5):672-681. Epub 2017 Feb 16.

1 Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center , Houston, Texas.

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http://dx.doi.org/10.1089/thy.2016.0395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802249PMC
May 2017

Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma.

Thyroid 2017 01 29;27(1):81-87. Epub 2016 Nov 29.

5 Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center , Houston, Texas.

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http://dx.doi.org/10.1089/thy.2016.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704769PMC
January 2017

Integrated analysis of germline and somatic variants in ovarian cancer.

Nat Commun 2014 ;5:3156

1] The Genome Institute, Washington University, St. Louis, Missouri 63108, USA [2] Department of Genetics, Washington University, St. Louis, Missouri 63108, USA [3] Siteman Cancer Center, Washington University, St. Louis, Missouri 63108, USA [4] Department of Medicine, Washington University, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/ncomms4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025965PMC
March 2016

The dilemma of heterogeneity tests in meta-analysis: a challenge from a simulation study.

PLoS One 2015 29;10(5):e0127538. Epub 2015 May 29.

Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127538PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449216PMC
March 2016

Association between Genetic Variants in DNA Double-Strand Break Repair Pathways and Risk of Radiation Therapy-Induced Pneumonitis and Esophagitis in Non-Small Cell Lung Cancer.

Cancers (Basel) 2016 Feb 18;8(2). Epub 2016 Feb 18.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers8020023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773746PMC
February 2016

A common founding clone with TP53 and PTEN mutations gives rise to a concurrent germ cell tumor and acute megakaryoblastic leukemia.

Cold Spring Harb Mol Case Stud 2016 Jan;2(1):a000687

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, Missouri 63110, USA;; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA;

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http://dx.doi.org/10.1101/mcs.a000687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849848PMC
January 2016

Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.

PLoS One 2015 23;10(3):e0120585. Epub 2015 Mar 23.

Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120585PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370741PMC
December 2015

Thyroid Gland Malignancies.

Hematol Oncol Clin North Am 2015 Dec;29(6):1123-43

Pathology Head and Neck Section, Department of Pathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 85, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.hoc.2015.07.011DOI Listing
December 2015

[Challenges to evidence-based medicine in an era of artificial intelligence].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2015 Sep;27(9):709-11

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September 2015

Genome Modeling System: A Knowledge Management Platform for Genomics.

PLoS Comput Biol 2015 Jul 9;11(7):e1004274. Epub 2015 Jul 9.

The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, United States of America; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America; Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497734PMC
July 2015

The origin of novel avian influenza A (H7N9) and mutation dynamics for its human-to-human transmissible capacity.

PLoS One 2014 26;9(3):e93094. Epub 2014 Mar 26.

Department of Computational Mathematics and Bio-Statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Institute for Emergency and Disaster Medicine, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan Province, China; Emergency Medicine Center, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan Province, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093094PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966860PMC
June 2015

Establishment of quantitative severity evaluation model for spinal cord injury by metabolomic fingerprinting.

PLoS One 2014 11;9(4):e93736. Epub 2014 Apr 11.

Program for Computational Biology, Systems Biology, and Translational Research, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Institute for Disaster and Emergency Medicine, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan Province, China; Department of Trauma Surgery, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan Province, China; Department of Computational Mathematics and Biostatistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Institute for Disaster and Emergency Medicine, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan Province, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093736PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984092PMC
December 2014

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nat Med 2014 Dec 19;20(12):1472-8. Epub 2014 Oct 19.

1] The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, USA. [2] Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA. [3] Department of Genetics, Washington University in St. Louis, St. Louis, Missouri, USA. [4] Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nm.3733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313872PMC
December 2014

Nomogram for predicting symptom severity during radiation therapy for head and neck cancer.

Otolaryngol Head Neck Surg 2014 Oct 7;151(4):619-26. Epub 2014 Aug 7.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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http://dx.doi.org/10.1177/0194599814545746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184965PMC
October 2014

Socioeconomic status is associated with depressive severity among patients with advanced non-small-cell lung cancer: treatment setting and minority status do not make a difference.

J Thorac Oncol 2014 Oct;9(10):1459-63

Departments of *Health Disparities, †General Oncology, ‡Symptom Research, and §Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston,Texas.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864153070
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http://dx.doi.org/10.1097/JTO.0000000000000284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514021PMC
October 2014

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

N Engl J Med 2014 Sep;371(11):1005-15

From the Departments of Pathology (K.G.R., D.P.-T., Y.-L.Y., K. McCastlain, G.S., J.M., S.-C.C., J.C., N.S.-M., I.I., J.W., J.R.D., C.G.M.), Computational Biology and Bioinformatics (Y.L., J.B., M.R., E.H., P.G., P.N., G.W., X.C., J.Z.), Biostatistics (D.P., C.C.), Pharmaceutical Sciences (S.W.P., M.V.R., W.E.E.), and Oncology (C.-H.P., S.J.), the Pediatric Cancer Genome Project (Y.L., L.D., C.L., M.R., J.E., J.C., K.B., R.S.F., E.H., P.G., P.N., G.W., X.C., D.Y., B.V., H.M., M.V.R., W.E.E., E.M., R.K.W., J.R.D., J.Z., C.G.M.), and Cytogenetics Shared Resource (M.V.), St. Jude Children's Research Hospital, Memphis, TN; the University of New Mexico Cancer Center and School of Medicine, Albuquerque (R.C.H., I-M.C., C.L.W.); the Genome Institute at Washington University (L.D., C.L., R.S.F., E.M., R.K.W.), the Department of Genetics, Washington University School of Medicine (L.D., C.L., R.S.F., E.M., R.K.W.), and Siteman Cancer Center, Washington University (E.M., R.K.W.) - all in St. Louis; Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville (M.D.); the Research Institute at Nationwide Children's Hospital (S.R., A.S., J.M.G.-F.), the Department of Pathology, College of Medicine, Ohio State University (N.A.H.), and Ohio State University Comprehensive Cancer Center (G.M., C.D.B., K. Mrózek, J.K.) - all in Columbus, OH; the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (N.J.W.), Scott and White Hospitals and Clinics and Texas A&M Health Science Center, Temple (G.G.), the University of Texas Health Science Center San Antonio, San Antonio (M.F.-J.), and the Departments of Leukemia and Stem Cell Transplantation, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (S.M.K., M.K.) - all in Texas; Maine Children's Cancer Program, Scarborough (E.C.L.); New York University Cancer Institute, New York (W.L.C.), and the Department of Medicine (Oncology), Albert Einstein

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http://dx.doi.org/10.1056/NEJMoa1403088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191900PMC
September 2014

Comprehensive level one trauma center could lower in-hospital mortality of severe trauma in China.

Biomed Environ Sci 2014 Jul;27(7):537-43

Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Institute for Disaster and Emergency Medicine Research, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu 610101, Sichuan, China; Trauma Surgery Center, East Branch, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu 610101, Sichuan, China.

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http://dx.doi.org/10.3967/bes2014.084DOI Listing
July 2014

Telomere length in peripheral blood leukocytes and lung cancer risk: a large case-control study in Caucasians.

Cancer Res 2014 May 11;74(9):2476-86. Epub 2014 Mar 11.

Authors' Affiliations: Departments of Epidemiology, Radiation Oncology, Thoracic/Head and Neck Medical Oncology, and Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357479PMC
May 2014

Is omega-3 fatty acids enriched nutrition support safe for critical ill patients? A systematic review and meta-analysis.

Nutrients 2014 May 30;6(6):2148-64. Epub 2014 May 30.

Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, Chengdu 610101, China.

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http://dx.doi.org/10.3390/nu6062148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073140PMC
May 2014

MSIsensor: microsatellite instability detection using paired tumor-normal sequence data.

Bioinformatics 2014 Apr 25;30(7):1015-6. Epub 2013 Dec 25.

Departments of Genetics and Mathematics, The Genome Institute, Department of Genetics, Division of Statistical Genomics, Department of Medicine and Siteman Cancer Center, Washington University in St. Louis, MO 63108, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btt755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967115PMC
April 2014

Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes.

Proc Natl Acad Sci U S A 2013 Nov 28;110(46):E4393-402. Epub 2013 Oct 28.

Lewis-Sigler Institute for Integrative Genomics and Department of Molecular Biology, Princeton University, Princeton, NJ 08544.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1318100110
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http://dx.doi.org/10.1073/pnas.1318100110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831991PMC
November 2013

High symptom burden prior to radiation therapy for head and neck cancer: a patient-reported outcomes study.

Head Neck 2013 Oct 20;35(10):1490-8. Epub 2012 Nov 20.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/hed.23181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788079PMC
October 2013

Prognostic value of patient-reported symptom interference in patients with late-stage lung cancer.

Qual Life Res 2013 Oct 31;22(8):2143-50. Epub 2013 Jan 31.

Department of Mathematics and Statistics, Kennesaw State University, Kennesaw, Georgia.

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http://dx.doi.org/10.1007/s11136-013-0356-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724766PMC
October 2013

Current challenges to the clinical translation of brain machine interface technology.

Int Rev Neurobiol 2012 ;107:137-60

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/B978-0-12-404706-8.00008-5DOI Listing
September 2013

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

N Engl J Med 2013 05 1;368(22):2059-74. Epub 2013 May 1.

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http://dx.doi.org/10.1056/NEJMoa1301689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767041PMC
May 2013

Systematic evaluation of apoptotic pathway gene polymorphisms and lung cancer risk.

Carcinogenesis 2012 Sep 4;33(9):1699-706. Epub 2012 Jun 4.

Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/carcin/bgs192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514904PMC
September 2012

Initial medical attention on patients with early-stage non-small cell lung cancer.

PLoS One 2012 7;7(3):e32644. Epub 2012 Mar 7.

Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032644PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296738PMC
August 2012

Malnutrition in hospitalized people living with HIV/AIDS: evidence from a cross-sectional study from Chengdu, China.

Asia Pac J Clin Nutr 2011 ;20(4):544-50

West China Hospital, Sichuan University, Department of Clinical Nutrition, Chengdu, China.

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http://apjcn.org/update%5Cpdf%5C2011%5C4%5C544-550%5C544.pdf
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February 2012

Efficacy of hypocaloric parenteral nutrition for surgical patients: a systematic review and meta-analysis.

Clin Nutr 2011 Dec 24;30(6):730-7. Epub 2011 Jun 24.

Department of Trauma Surgery, East Branch, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Sciences, No.585, Da Mian Hong He Bei Lu, Long Quan District, Chengdu 610110, PR China.

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http://dx.doi.org/10.1016/j.clnu.2011.05.006DOI Listing
December 2011

Common genetic variants in cell cycle pathway are associated with survival in stage III-IV non-small-cell lung cancer.

Carcinogenesis 2011 Dec 28;32(12):1867-71. Epub 2011 Sep 28.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1155 Pressler Street, Houston, TX 77030, USA.

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http://dx.doi.org/10.1093/carcin/bgr217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220611PMC
December 2011

Genetic variations in the regulator of G-protein signaling genes are associated with survival in late-stage non-small cell lung cancer.

PLoS One 2011 17;6(6):e21120. Epub 2011 Jun 17.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021120PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117866PMC
November 2011

Phase 2 study of high-dose proton therapy with concurrent chemotherapy for unresectable stage III nonsmall cell lung cancer.

Cancer 2011 Oct 22;117(20):4707-13. Epub 2011 Mar 22.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA.

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http://doi.wiley.com/10.1002/cncr.26080
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http://dx.doi.org/10.1002/cncr.26080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174272PMC
October 2011