Charles L Brooks

J Chem Theory Comput 2019 Feb 4;15(2):799-802. Epub 2019 Feb 4.

Department of Computational Medicine & Bioinformatics , University of Michigan , Ann Arbor , Michigan 48109 , United States.

J Am Chem Soc 2018 Dec 19;140(48):16560-16569. Epub 2018 Nov 19.

Protein Sci 2018 Nov;27(11):1910-1922

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, 48109.

Nat Struct Mol Biol 2018 Nov;25(11):990-991

Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.

Mol Cell 2018 11;72(3):541-552.e6

Single Molecule Analysis Group, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA; Center for RNA Biomedicine, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

Proc Natl Acad Sci U S A 2018 09 20;115(36):8960-8965. Epub 2018 Aug 20.

Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109;

Annu Rev Virol 2018 09;5(1):477-488

Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California 92037, USA; email:

J Phys Chem Lett 2018 Jun 6;9(12):3328-3332. Epub 2018 Jun 6.

Department of Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States.

Chem Sci 2018 Feb 30;9(7):1769-1773. Epub 2017 Nov 30.

Department of Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , USA . Email:

J Comput Aided Mol Des 2018 01 7;32(1):89-102. Epub 2017 Sep 7.

Department of Computational Medicine and Bioinformatics, Univeristy of Michigan, Ann Arbor, MI, 48109, USA.

Phys Chem Chem Phys 2018 Jan;20(2):1021-1029

Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

J Biol Chem 2017 09 24;292(36):14963-14976. Epub 2017 Jul 24.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109-1055

Nucleic Acids Res 2017 09;45(16):9706-9715

Single Molecule Analysis Group and Center for RNA Biomedicine, Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109-1055, USA.

J Comput Chem 2017 Jun 16;38(15):1270-1274. Epub 2017 Apr 16.

Departments of Biophysics and Chemistry, University of Michigan, Ann Arbor, MI, 48109.

J Comput Chem 2017 Jun 11;38(21):1879-1886. Epub 2017 May 11.

Department of Biological Sciences and Bioengineering Program, Lehigh University, Bethlehem, Pennsylvania.

J Chem Theory Comput 2017 Jun 26;13(6):2501-2510. Epub 2017 May 26.

Department of Computational Medicine & Bioinformatics, ‡Department of Chemistry, §Biophysics Program, University of Michigan , Ann Arbor, Michigan 48109, United States.

Small 2017 05 7;13(18). Epub 2017 Mar 7.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, MI, 48109, USA.

J Phys Chem B 2017 04 10;121(15):3626-3635. Epub 2017 Feb 10.

Department of Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.

Sci Adv 2017 Apr 14;3(4):e1700325. Epub 2017 Apr 14.

Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

ACS Chem Biol 2016 12 31;11(12):3374-3382. Epub 2016 Oct 31.

Program in Chemical Biology, ‡Department of Chemistry, §Department of Biophysics, and ∥Life Sciences Institute, University of Michigan , 930 N. University Ave., Ann Arbor, Michigan 48109, United States.

Angew Chem Int Ed Engl 2016 11 28;55(48):14997-15001. Epub 2016 Oct 28.

Department of Chemistry, University of Michigan, Ann Arbor, USA.

Bioorg Med Chem 2016 10 18;24(20):4812-4825. Epub 2016 Jun 18.

Computer-Aided Drug Design Center, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201, United States. Electronic address:

J Comput Chem 2016 09 12;37(24):2171-80. Epub 2016 Jul 12.

Department of Chemistry and Biophysics Program, University of Michigan, 930 N. University Ave, Ann Arbor, Michigan, 48109.

J Am Chem Soc 2016 08 2;138(31):9826-39. Epub 2016 Aug 2.

Department of Molecular, Cellular and Developmental Biology, and the Howard Hughes Medical Institute, University of Michigan , Ann Arbor, Michigan 48109, United States.

Nat Struct Mol Biol 2016 07 30;23(7):691-7. Epub 2016 May 30.

Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.

J Comput Chem 2016 Apr 20;37(10):927-39. Epub 2016 Jan 20.

Department of Chemistry, University of Michigan, 930 N. University Ave., Ann Arbor, Michigan, 48109.

J Comput Chem 2016 Mar 6;37(6):587-94. Epub 2015 Aug 6.

Department of Chemistry, The University of Michigan, Ann Arbor, Michigan, 48109.

J Comput Chem 2016 Mar 21;37(8):753-62. Epub 2015 Dec 21.

Department of Chemistry, University of Michigan, Ann Arbor, Michigan.

Nucleic Acids Res 2016 Jan 19;44(1):402-12. Epub 2015 Oct 19.

Department of Biophysics, University of Michigan, Ann Arbor, MI 48109, USA Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA

J Chem Theory Comput 2016 Jan 3;12(1):405-13. Epub 2015 Dec 3.

Department of Molecular Biosciences and Center for Computational Biology, The University of Kansas , Lawrence, Kansas 66047, United States.

Protein Sci 2016 Jan;25(1):5-8

Department of Medicinal Chemistry, and Pharmacology Purdue University, West Lafayette, IN, 47907.

Phys Rev E 2016 Jan 28;93(1):012417. Epub 2016 Jan 28.

Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, California 90095, USA.

J Mol Biol 2015 Nov 12;427(22):3613-3624. Epub 2015 Sep 12.

Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI 48109-2218, USA; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109-1055, USA; Biophysics Program, University of Michigan, Ann Arbor, MI 48109-1055, USA. Electronic address:

Proc Natl Acad Sci U S A 2015 Oct 29;112(41):E5608-17. Epub 2015 Sep 29.

Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109;

J Am Chem Soc 2015 Aug 11;137(32):10190-8. Epub 2015 Aug 11.

†Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Langmuir 2015 Jun 27;31(22):6145-53. Epub 2015 May 27.

†Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109, United States.

J Phys Chem B 2015 May 7;119(20):6217-24. Epub 2015 May 7.

†Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, Michigan 48109, United States.

J Mol Biol 2015 Apr 10;427(8):1670-80. Epub 2015 Jan 10.

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA; Biophysics Program, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

J Struct Biol 2015 Apr 16;190(1):47-55. Epub 2015 Feb 16.

Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.

J Phys Chem B 2015 Apr 22;119(13):4601-7. Epub 2015 Mar 22.

†Department of Chemistry and ‡Biophysics Program, University of Michigan, 930 N. University Ave., Ann Arbor, Michigan, 48109, United States.

Proteins 2015 Mar 21;83(3):403-410. Epub 2015 Jan 21.

Department of Biological Chemistry, Howard Hughes Medical Institute, University of Michigan, Ann Arbor MI 48109 USA.

J Am Chem Soc 2015 Mar 18;137(8):2892-900. Epub 2015 Feb 18.

Department of Chemistry and ‡Biophysics Program, University of Michigan , Ann Arbor, Michigan 48109, United States.

J Am Chem Soc 2015 Mar 9;137(10):3592-9. Epub 2015 Mar 9.

∥Departments of Biochemistry and Chemistry, Duke University School of Medicine, Durham, North Carolina 27710, United States.

J Chem Theory Comput 2015 Mar;11(3):1267-77

Department of Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109, United States.

BMC Bioinformatics 2015 Feb 1;16:33. Epub 2015 Feb 1.

Department of Computational Medicine and Bioinformatics, Medical School, University of Michigan, Ann Arbor, MI, USA.

Proc Natl Acad Sci U S A 2015 Feb 2;112(7):2034-9. Epub 2015 Feb 2.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, MI 48109; and

Annu Rev Biochem 2014 5;83:441-66. Epub 2014 Mar 5.

Departments of 1Biophysics and.

J Chem Theory Comput 2015 Jan;11(1):325-31

Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States

Nucleic Acids Res 2014 Oct 12;42(18):11792-804. Epub 2014 Sep 12.

Department of Biochemistry and Chemistry, Duke University School of Medicine, Durham, NC 27710, USA

J Phys Chem B 2014 Oct 15;118(42):12168-75. Epub 2014 Oct 15.

Department of Chemistry and Biophysics, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109-1055, United States.

J Phys Chem B 2014 Oct 14;118(42):12176-85. Epub 2014 Oct 14.

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University , Si Pai Lou 2, Nanjing 210096, China.

J Phys Chem Lett 2014 Oct 19;5(19):3441-3444. Epub 2014 Sep 19.

Department of Chemistry and Biophysics Program, The University of Michigan , Ann Arbor, Michigan 48109, United States.

Nucleic Acids Res 2014 Oct 7;42(19):12126-37. Epub 2014 Oct 7.

Department of Chemistry, University of Michigan, 930 N University, Ann Arbor, MI 48109, USA Department of Biophysics, University of Michigan, 930 N University, Ann Arbor, MI 48109, USA

J Mol Biol 2014 Sep 9;426(19):3201-3213. Epub 2014 May 9.

Department of Chemistry and Biophysics Program, University of Michigan, 930 North University Avenue, Ann Arbor, MI 48109, USA. Electronic address:

J Comput Chem 2014 Sep 4;35(24):1757-61. Epub 2014 Jul 4.

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, 48109; Department of Biophysics, University of Michigan, Ann Arbor, Michigan, 48109, Fax: +1 (734) 647 1604.

Proc Natl Acad Sci U S A 2014 Aug 7;111(33):12067-72. Epub 2014 Jul 7.

Departments of Chemistry andBiophysics, and

PLoS Comput Biol 2013 14;9(11):e1003324. Epub 2013 Nov 14.

Department of Chemistry, The University of Michigan, Ann Arbor, Michigan, United States of America.

Proteins 2014 Jul 15;82(7):1319-31. Epub 2014 Jan 15.

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, 48109.

J Phys Chem B 2014 Jul 29;118(28):8118-27. Epub 2014 May 29.

Department of Chemistry and ‡Biophysics Program, University of Michigan , 930 N. University Avenue , Ann Arbor, Michigan 48109-1055, USA.

Proc Natl Acad Sci U S A 2014 Jul 7;111(29):10562-7. Epub 2014 Jul 7.

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605;

Comput Struct Biotechnol J 2012 30;2:e201209018. Epub 2012 Nov 30.

University of Michigan, Department of Chemistry and Biophysics, 930 North University Avenue, Ann Arbor, MI 48109 USA.

J Am Chem Soc 2014 Jun 3;136(24):8496-9. Epub 2014 Jun 3.

Department of Chemistry and ‡Biophysics Program, University of Michigan , Ann Arbor, Michigan 48109, United States.

J Phys Chem B 2014 May 16;118(21):5670-80. Epub 2014 May 16.

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University , Si Pai Lou 2, Nanjing 210096, China.

J Phys Chem B 2014 Apr 11;118(13):3532-42. Epub 2014 Feb 11.

Department of Chemistry, University of Michigan , Ann Arbor, Michigan, United States.

J Struct Biol 2014 Mar 19;185(3):375-82. Epub 2013 Dec 19.

Health Science Research Facility 130, 149 Beaumont Avenue, Department of Molecular Physiology & Biophysics, University of Vermont, Burlington, VT 05405, United States.

J Phys Chem B 2014 Mar 3;118(10):2615-27. Epub 2014 Mar 3.

Departments of Biophysics and ‡Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109, United States.

J Phys Chem B 2014 Mar 6;118(11):2904-12. Epub 2014 Mar 6.

Department of Chemistry, ‡Department of Biophysics, and §Department of Environmental Health Sciences, University of Michigan , Ann Arbor, Michigan 48109, United States.

J Am Chem Soc 2014 Feb 13;136(8):3097-107. Epub 2014 Feb 13.

Department of Molecular and Cell Biology, University of Connecticut , Storrs, Connecticut 06269, United States.

J Am Chem Soc 2014 Jan 16;136(1):188-94. Epub 2013 Dec 16.

Department of Chemistry, University of Michigan , 930 N. University Ave., Ann Arbor, Michigan 48109, United States.

Top Curr Chem 2013 ;337:165-87

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, MI, 48109, USA.

Nucleic Acids Res 2013 Dec 3;41(22):10462-75. Epub 2013 Sep 3.

Biophysics, University of Michigan, Ann Arbor, MI 48109, USA, Single Molecule Analysis Group, University of Michigan, Ann Arbor, MI 48109, USA, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA, Program in Chemical Biology, University of Michigan, Ann Arbor, MI 48109, USA, Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA and Center for Theoretical Biological Physics, University of California San Diego, San Diego, CA 92037, USA.

ACS Chem Biol 2013 Dec 24;8(12):2778-84. Epub 2013 Oct 24.

Department of Chemical Engineering, University of New Hampshire , Durham, New Hampshire 03824, United States of America.

PLoS Comput Biol 2013 7;9(2):e1002905. Epub 2013 Feb 7.

Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.

J Phys Chem B 2013 Oct 1;117(42):13219-25. Epub 2013 Jul 1.

Department of Chemistry, The University of Michigan , Ann Arbor, Michigan, United States.

J Am Chem Soc 2013 Jul 22;135(30):10906-9. Epub 2013 Jul 22.

Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

PLoS Comput Biol 2012 27;8(12):e1002839. Epub 2012 Dec 27.

Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America.

Protein Sci 2013 May 30;22(5):595-604. Epub 2013 Mar 30.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109, USA.

J Am Chem Soc 2013 May 29;135(18):6766-9. Epub 2013 Apr 29.

Department of Chemistry and Biophysics, University of Michigan, Ann Arbor, Michigan 48109, United States.

J Comput Chem 2013 Apr 7;34(11):893-903. Epub 2013 Jan 7.

Department of Chemistry & Department of Biophysics University of Michigan, 930 N. University Ave. Ann Arbor, MI 48109 USA

Proc Natl Acad Sci U S A 2013 Apr 4;110(14):E1254-62. Epub 2013 Mar 4.

Howard Hughes Medical Institute and Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, MI 48109-1055, USA.

J Phys Chem B 2013 Apr 1;117(14):3738-46. Epub 2013 Apr 1.

Department of Chemistry and Biophysics Program, Department of Biological Chemistry, and Biophysics Program, University of Michigan , Ann Arbor, Michigan, USA.

J Am Chem Soc 2013 Mar 22;135(9):3363-6. Epub 2013 Feb 22.

Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan 48109, United States.

J Am Chem Soc 2013 Mar 15;135(12):4729-34. Epub 2013 Mar 15.

Department of Chemistry, The University of Michigan, Ann Arbor, Michigan 48109, USA.

J Phys Chem Lett 2013 Mar 12;4(5):760-766. Epub 2013 Feb 12.

Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, Michigan 48109, United States.

J Chem Theory Comput 2013 Feb 3;9(2):935-943. Epub 2013 Jan 3.

Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, Michigan 48109, United States.

J Comput Chem 2013 Jan;34(1)

Angew Chem Int Ed Engl 2012 Nov 8;51(45):11258-62. Epub 2012 Oct 8.

Department of Chemistry, University of Michigan, Ann Arbor, USA.

J Am Chem Soc 2012 Sep 7;134(37):15357-70. Epub 2012 Sep 7.

Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.

Structure 2012 Sep;20(9):1453-62

Department of Chemistry and Biophysics Program, University of Michigan, 930 North University Avenue, Chem 2006, Ann Arbor, MI 48109, USA.

Endocr Rev 2012 Aug 10;33(4):504-25. Epub 2012 May 10.

Departments of Veterinary Biosciences and Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA.

J Phys Chem B 2012 Jul 27;116(29):8604-9. Epub 2012 Mar 27.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109, United States.

J Phys Chem B 2012 May 7;116(19):5604-11. Epub 2012 May 7.

Department of Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109, United States.

Proc Natl Acad Sci U S A 2012 Feb 30;109(7):2342-7. Epub 2012 Jan 30.

Natuur- en Sterrenkunde and LaserLab, VU University, 1081 HV Amsterdam, The Netherlands.

Biophys J 2012 Feb 7;102(3):606-12. Epub 2012 Feb 7.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan, USA.

J Comput Chem 2012 Jan 1;33(2):189-202. Epub 2011 Nov 1.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109, USA.

J Chem Theory Comput 2012 ;8(9):3044-3052

Department of Chemistry, The University of Michigan, Ann Arbor, MI, and Department of Chemistry and Biophysics Program, The University of Michigan, Ann Arbor, MI.

J Chem Theory Comput 2012 Jan;8(1):36-46

Department of Chemistry, University of Michigan, 930 N. University, Ann Arbor, Michigan 48109, United States.

J Am Chem Soc 2011 Dec 9;133(48):19393-8. Epub 2011 Nov 9.

Department of Chemistry and Biophysics Program, University of Michigan, Ann Arbor, Michigan 48109, USA.

J Am Chem Soc 2011 Dec 23;133(50):20072-5. Epub 2011 Nov 23.

Department of Chemistry, University of Michigan, 930 North University, Ann Arbor, Michigan 48109, USA.

J Chem Theory Comput 2011 Sep;7(9):2728-2739

Department of Chemistry & Department of Biophysics. University of Michigan. 930 N. University Ave. Ann Arbor, MI 48109 USA.