Publications by authors named "Charles J Sherr"

69Publications

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.

Cell 2020 04 31;181(2):424-441.e21. Epub 2020 Mar 31.

Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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April 2020

Surprising regulation of cell cycle entry.

Authors:
Charles J Sherr

Science 2019 12;366(6471):1315-1316

St. Jude Children's Research Hospital, Memphis, TN, USA.

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December 2019

Sexually dimorphic tumor suppression by small mitochondrial .

Oncotarget 2019 Feb 8;10(12):1235-1237. Epub 2019 Feb 8.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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February 2019

Acquired palbociclib resistance in KRAS-mutant lung cancer.

Authors:
Charles J Sherr

Oncotarget 2018 Aug 28;9(67):32734-32735. Epub 2018 Aug 28.

Charles J. Sherr: Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN, USA.

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August 2018

Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

Sci Rep 2018 06 7;8(1):8733. Epub 2018 Jun 7.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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June 2018

Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of tumor suppressor-deficient mice.

Proc Natl Acad Sci U S A 2017 07 26;114(28):7420-7425. Epub 2017 Jun 26.

Howard Hughes Medical Institute, Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN 38105;

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July 2017

A New Cell-Cycle Target in Cancer - Inhibiting Cyclin D-Dependent Kinases 4 and 6.

Authors:
Charles J Sherr

N Engl J Med 2016 Nov;375(20):1920-1923

From the Howard Hughes Medical Institute and the Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN.

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November 2016

Targeting CDK4 and CDK6: From Discovery to Therapy.

Cancer Discov 2016 Apr 11;6(4):353-67. Epub 2015 Dec 11.

Early Drug Development Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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April 2016

Forging a signature of in vivo senescence.

Nat Rev Cancer 2015 Jul;15(7):397-408

Department of Tumor Cell Biology and The Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.

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July 2015

Janus kinase inhibition by ruxolitinib extends dasatinib- and dexamethasone-induced remissions in a mouse model of Ph+ ALL.

Blood 2015 Feb 12;125(9):1444-51. Epub 2014 Dec 12.

Cancer Biology & Genetics Program, and Howard Hughes Medical Institute, and Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN.

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February 2015

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.

Genes Dev 2014 Aug;28(16):1800-14

Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA; Cell and Developmental Biology Program, Weill Graduate School of Medical Sciences, Cornell University, New York, New York 10065, USA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA;

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August 2014

Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model.

Pharmacogenet Genomics 2014 May;24(5):263-71

Departments of aPharmaceutical Sciences bPathology cBiostatistics dOncology, St Jude Children's Research Hospital (Current address Puma Biotechnology Inc., Los Angeles, CA 90024, USA) eDepartment of Tumor Cell Biology, Howard Hughes Medical Institute, St Jude Children's Research Hospital, Memphis, Tennessee, USA.

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May 2014

Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells.

Proc Natl Acad Sci U S A 2013 Mar 4;110(12):E1112-21. Epub 2013 Mar 4.

Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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March 2013

Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia.

Exp Hematol 2013 Apr 23;41(4):377-86. Epub 2012 Nov 23.

Division of Pediatric Hematology-Oncology, Vanderbilt University, Nashville, TN, USA.

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April 2013

How politics trumped peer review at Texas cancer institute.

Authors:
Charles J Sherr

BMJ 2012 Nov 15;345:e7334. Epub 2012 Nov 15.

Department of Tumor Cell Biology, St Jude Children’s Research Hospital, Memphis, USA.

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November 2012

Ink4-Arf locus in cancer and aging.

Authors:
Charles J Sherr

Wiley Interdiscip Rev Dev Biol 2012 Sep-Oct;1(5):731-41

Howard Hughes Medical Institute, Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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February 2014

Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells.

PLoS Genet 2011 Jul 21;7(7):e1002157. Epub 2011 Jul 21.

Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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July 2011