Publications by authors named "Charles J Lowenstein"

81Publications

Severe COVID-19 is a Microvascular Disease.

Circulation 2020 Sep 2. Epub 2020 Sep 2.

Cardiovascular Division, Brigham and Womenâs Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.050354DOI Listing
September 2020

Acetylcholine Inhibits Platelet Activation.

J Pharmacol Exp Ther 2019 05 14;369(2):182-187. Epub 2019 Feb 14.

Aab Cardiovascular Research Institute, Department of Medicine (J.A.B., S.K.T., R.A.S., M.A.M., S.J.C., C.N.M., C.J.L.) and Department of Pharmacology and Physiology (L.E.T., D.I.Y.), University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.1124/jpet.118.253583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439456PMC
May 2019

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Circulation 2019 01;139(5):620-635

Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438386PMC
January 2019

New vascular insights into premature aging.

J Clin Invest 2019 02 18;129(2):492-493. Epub 2018 Dec 18.

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https://www.jci.org/articles/view/125616
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http://dx.doi.org/10.1172/JCI125616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355212PMC
February 2019

Sarnoff Cardiovascular Research Foundation: Inspiring the Physician-Scientists of Tomorrow.

Circulation 2018 08;138(6):554-556

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (J.H.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.030397DOI Listing
August 2018

Do elevated blood levels of omega-3 fatty acids modify effects of particulate air pollutants on fibrinogen?

Air Qual Atmos Health 2018 3;11(7):791-799. Epub 2018 Jun 3.

1Division of Pulmonary and Critical Care, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Box 692, Rochester, NY 14642 USA.

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http://link.springer.com/10.1007/s11869-018-0586-0
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http://dx.doi.org/10.1007/s11869-018-0586-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097058PMC
June 2018

VAMP-3 mediates platelet endocytosis.

Blood 2017 12;130(26):2816-2818

UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY.

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http://dx.doi.org/10.1182/blood-2017-10-808576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746672PMC
December 2017

Variation in Do-Not-Resuscitate Orders and Implications for Heart Failure Risk-Adjusted Hospital Mortality Metrics.

JACC Heart Fail 2017 10;5(10):743-752

Division of Pulmonary, Allergy, Sleep, and Critical Care Medicine, Boston University Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jchf.2017.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552359PMC
October 2017

Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients.

Environ Res 2017 04 4;154:352-361. Epub 2017 Feb 4.

Department of Public Health Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA; Department of Environmental Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2017.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375102PMC
April 2017

Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.

Arterioscler Thromb Vasc Biol 2017 Feb 29;37(2):264-270. Epub 2016 Dec 29.

From the Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, NY (Q.M.Z., K.A.K., S.T., M.A.M., C.N.M., J.M.M., C.J.L.); Division of Intramural Research, National Heart, Lung and Blood Institute (NHLBI), National Institutes of Health, and NHLBI Framingham Heart Study, Framingham, MA (M.-H.C., A.D.J., C.J.O.D.); and Cardiovascular Division, Massachusetts General Hospital, Harvard Medical School, Boston (C.J.O.D.).

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http://dx.doi.org/10.1161/ATVBAHA.116.308614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269475PMC
February 2017

A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.

Arterioscler Thromb Vasc Biol 2016 06 21;36(6):1058-75. Epub 2016 Apr 21.

From the Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY (J.M.M., Q.M.Z., C.J.L.); and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA (Q.M.Z.).

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http://dx.doi.org/10.1161/ATVBAHA.116.304790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882230PMC
June 2016

A Novel Anti-Inflammatory Effect for High Density Lipoprotein.

PLoS One 2015 17;10(12):e0144372. Epub 2015 Dec 17.

Departments of Medicine, Division of Cardiology, University of Rochester School of Medicine, Box 679, 601 Elmwood Avenue, Rochester, NY, 14652, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144372PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683005PMC
June 2016

SNAP23 Regulates Endothelial Exocytosis of von Willebrand Factor.

PLoS One 2015 12;10(8):e0118737. Epub 2015 Aug 12.

Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118737PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534191PMC
May 2016

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Authors:
Jie Huang Jennifer E Huffman Munekazu Yamakuchi Munekazu Yamkauchi Stella Trompet Folkert W Asselbergs Maria Sabater-Lleal David-Alexandre Trégouët Wei-Min Chen Nicholas L Smith Marcus E Kleber So-Youn Shin Diane M Becker Weihong Tang Abbas Dehghan Andrew D Johnson Vinh Truong Lasse Folkersen Qiong Yang Tiphaine Oudot-Mellkah Brendan M Buckley Jason H Moore Frances M K Williams Harry Campbell Günther Silbernagel Veronique Vitart Igor Rudan Geoffrey H Tofler Gerjan J Navis Anita Destefano Alan F Wright Ming-Huei Chen Anton J M de Craen Bradford B Worrall Alicja R Rudnicka Ann Rumley Ebony B Bookman Bruce M Psaty Fang Chen Keith L Keene Oscar H Franco Bernhard O Böhm Andre G Uitterlinden Angela M Carter J Wouter Jukema Naveed Sattar Joshua C Bis Mohammad A Ikram Michèle M Sale Barbara McKnight Myriam Fornage Ian Ford Kent Taylor P Eline Slagboom Wendy L McArdle Fang-Chi Hsu Anders Franco-Cereceda Alison H Goodall Lisa R Yanek Karen L Furie Mary Cushman Albert Hofman Jacqueline C M Witteman Aaron R Folsom Saonli Basu Nena Matijevic Wiek H van Gilst James F Wilson Rudi G J Westendorp Sekar Kathiresan Muredach P Reilly Russell P Tracy Ozren Polasek Bernhard R Winkelmann Peter J Grant Hans L Hillege Francois Cambien David J Stott Gordon D Lowe Timothy D Spector James B Meigs Winfried Marz Per Eriksson Lewis C Becker Pierre-Emmanuel Morange Nicole Soranzo Scott M Williams Caroline Hayward Pim van der Harst Anders Hamsten Charles J Lowenstein David P Strachan Christopher J O'Donnell

Arterioscler Thromb Vasc Biol 2014 May 27;34(5):1093-101. Epub 2014 Feb 27.

From National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (J.H., A.D.J., C.J.O.); Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, MD (J.H., A.D.J., C.J.O.); MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, United Kingdom (J.E.H., V.V., A.F.W., C.H.); The Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY (M.Y., C.J.L.); Departments of Cardiology (S.T., J.W.J.), Gerontology and Geriatrics (S.T., A.J.M.d.C., R.G.J.W.), and Molecular Epidemiology (P.E.S.), Leiden University Medical Center, the Netherlands; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands (F.W.A.); Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands (F.W.A.); Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, United Kingdom (F.W.A.); Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine (M.S.-L., L.F., P.E., A.H.), Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden; INSERM UMRS 937, Pierre et Marie Curie University, Paris, France (D.-A.T., V.T., T.O.M., F.C.); ICAN Institute for Cardiometabolism and Nutrion, Paris, France (D.-A.T., V.T., F.C.); Departments of Public Health Sciences (W.M.C., B.B.W., F.C.) and Biochemistry and Molecular Genetics (M.M.S.), Center for Public Health Genomics, University of Virginia, Charlottesville, VA; Departments of Epidemiology (N.L.S., B.M.P., B.M.), Medicine (B.M.P., J.C.B.), and Health Services (B.M.P.), University of Washington, Seattle, WA; Group Health Research Institute, Group Health Cooperative, Seattle, WA (N.L.S., B.M.P.); Seattle Epidemiologic Research and Information Center, VA Office of Research and

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http://dx.doi.org/10.1161/ATVBAHA.113.302088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009733PMC
May 2014

Enhanced assay of endothelial exocytosis using extracellular matrix components.

Anal Biochem 2014 May 20;452:19-24. Epub 2014 Feb 20.

Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2014.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048756PMC
May 2014

MicroRNA-22 regulates hypoxia signaling in colon cancer cells.

PLoS One 2011 23;6(5):e20291. Epub 2011 May 23.

Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020291PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100326PMC
September 2011

Vav-Vav-Vav-voom!

Blood 2011 May;117(21):5557-9

University of Rochester School of Medicine and Dentistry, USA.

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http://dx.doi.org/10.1182/blood-2011-04-345561DOI Listing
May 2011

Thioredoxin increases exocytosis by denitrosylating N-ethylmaleimide-sensitive factor.

J Biol Chem 2011 Apr 15;286(13):11179-84. Epub 2011 Feb 15.

Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M110.201780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064172PMC
April 2011

VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes.

J Mol Cell Cardiol 2010 Nov 27;49(5):791-800. Epub 2010 Aug 27.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949530PMC
http://dx.doi.org/10.1016/j.yjmcc.2010.08.020DOI Listing
November 2010

Ets-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cells.

Arterioscler Thromb Vasc Biol 2010 Oct 29;30(10):1990-7. Epub 2010 Jul 29.

Cellular and Molecular Medicine Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1161/ATVBAHA.110.211706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121560PMC
October 2010

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis.

Proc Natl Acad Sci U S A 2010 Apr 22;107(14):6334-9. Epub 2010 Mar 22.

Department of Medicine, Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1073/pnas.0911082107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851979PMC
April 2010

High-density lipoprotein metabolism and endothelial function.

Curr Opin Endocrinol Diabetes Obes 2010 Apr;17(2):166-70

Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1097/MED.0b013e32833727eeDOI Listing
April 2010

Aldosterone activates endothelial exocytosis.

Proc Natl Acad Sci U S A 2009 Mar 17;106(10):3782-7. Epub 2009 Feb 17.

Department of Medicine, Graduate Program in Pathobiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0804037106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2656157PMC
March 2009

MiR-34, SIRT1 and p53: the feedback loop.

Cell Cycle 2009 Mar 2;8(5):712-5. Epub 2009 Mar 2.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.4161/cc.8.5.7753DOI Listing
March 2009

miR-34a repression of SIRT1 regulates apoptosis.

Proc Natl Acad Sci U S A 2008 Sep 28;105(36):13421-6. Epub 2008 Aug 28.

Departments of Medicine and Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0801613105
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http://dx.doi.org/10.1073/pnas.0801613105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533205PMC
September 2008

Epigallocatechin gallate inhibits endothelial exocytosis.

Biol Chem 2008 Jul;389(7):935-41

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1515/BC.2008.095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846414PMC
July 2008

Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling.

J Exp Med 2008 Jun 26;205(6):1491-503. Epub 2008 May 26.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1084/jem.20071728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413043PMC
June 2008

Glutamate mediates platelet activation through the AMPA receptor.

J Exp Med 2008 Mar 18;205(3):575-84. Epub 2008 Feb 18.

Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1084/jem.20071474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275381PMC
March 2008

MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1.

Proc Natl Acad Sci U S A 2008 Feb 28;105(5):1516-21. Epub 2008 Jan 28.

Cellular and Molecular Medicine Program and Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0707493105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234176PMC
February 2008

Myocardial reperfusion injury.

N Engl J Med 2007 Dec;357(23):2409; author reply 2409-10

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December 2007

Nitric oxide regulates vascular calcification by interfering with TGF- signalling.

Cardiovasc Res 2008 Jan 25;77(1):221-30. Epub 2007 Oct 25.

Department of Oral Disease Research, National Center for Geriatrics and Gerontology, 36-3 Gengo, Morioka-cho, Obu, Aichi 474-8511, Japan.

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http://dx.doi.org/10.1093/cvr/cvm049DOI Listing
January 2008

Inhibition of N-ethylmaleimide-sensitive factor protects against myocardial ischemia/reperfusion injury.

Circ Res 2007 Dec 11;101(12):1247-54. Epub 2007 Oct 11.

Department of Medicine, Division of Cardiology and Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.162610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836825PMC
December 2007

Outbreak management and implications of a nosocomial norovirus outbreak.

Clin Infect Dis 2007 Sep 18;45(5):534-40. Epub 2007 Jul 18.

Division of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1086/520666DOI Listing
September 2007

Nitric oxide regulation of protein trafficking in the cardiovascular system.

Cardiovasc Res 2007 Jul 3;75(2):240-6. Epub 2007 Apr 3.

The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.cardiores.2007.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213885PMC
July 2007

Novel pathogenetic mechanisms in myocarditis: nitric oxide signaling.

Heart Fail Clin 2005 Oct;1(3):345-61

The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.hfc.2005.06.002DOI Listing
October 2005

Inhibitor of NF kappa B alpha is a host sensor of coxsackievirus infection.

Cell Cycle 2007 Mar 25;6(5):503-6. Epub 2007 Mar 25.

Departamento de Fisiologia, Facultad de Medicina, Universidad de Alcala, Alcala de Henares, Spain.

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http://dx.doi.org/10.4161/cc.6.5.3918DOI Listing
March 2007

Antibody to human leukocyte antigen triggers endothelial exocytosis.

Proc Natl Acad Sci U S A 2007 Jan 17;104(4):1301-6. Epub 2007 Jan 17.

Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0602035104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783109PMC
January 2007

Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells.

J Biol Chem 2007 Mar 16;282(11):8134-41. Epub 2007 Jan 16.

Department of Oral Disease Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, 36-3 Gengo, Morioka, Obu, Aichi 474-8522, Japan.

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http://dx.doi.org/10.1074/jbc.M609962200DOI Listing
March 2007

Viral protease cleavage of inhibitor of kappaBalpha triggers host cell apoptosis.

Proc Natl Acad Sci U S A 2006 Dec 30;103(50):19051-6. Epub 2006 Nov 30.

Fundación Centro Nacional de Investigaciones Cardiovasculares, Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1073/pnas.0606019103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1748175PMC
December 2006

N-ethylmaleimide-sensitive factor: a redox sensor in exocytosis.

Biol Chem 2006 Oct-Nov;387(10-11):1377-83

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1515/BC.2006.173DOI Listing
December 2006

Stat3 mediates interleukin-6 [correction of interelukin-6] inhibition of human endothelial nitric-oxide synthase expression.

J Biol Chem 2006 Oct 3;281(40):30057-62. Epub 2006 Aug 3.

Department of Physiology, Universidad de Alcalá, Alcalá de Henares, 28871 Madrid, Spain.

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http://dx.doi.org/10.1074/jbc.M606279200DOI Listing
October 2006

What's in a name? eNOS and anaphylactic shock.

J Clin Invest 2006 Aug;116(8):2075-8

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1172/JCI29406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1523396PMC
August 2006

Nitric oxide inhibits exocytosis of cytolytic granules from lymphokine-activated killer cells.

Proc Natl Acad Sci U S A 2006 Aug 20;103(31):11689-94. Epub 2006 Jul 20.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0600275103
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http://dx.doi.org/10.1073/pnas.0600275103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544231PMC
August 2006

Beneficial effects of neuronal nitric oxide synthase in atherosclerosis.

Arterioscler Thromb Vasc Biol 2006 Jul;26(7):1417-8

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http://dx.doi.org/10.1161/01.ATV.0000226550.89264.91DOI Listing
July 2006

Mature hepatocyte growth factor/scatter factor on the surface of human granulocytes is released by a mechanism involving activated factor Xa.

J Immunol 2006 Jun;176(11):6945-53

Division of Biochemistry and Molecular Dentistry, Department of Developmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Sakuragaoka, Kagoshima, Japan.

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http://dx.doi.org/10.4049/jimmunol.176.11.6945DOI Listing
June 2006

Regulation of Weibel-Palade body exocytosis.

Trends Cardiovasc Med 2005 Nov;15(8):302-8

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1016/j.tcm.2005.09.005DOI Listing
November 2005

A novel inhibitor of N-ethylmaleimide-sensitive factor decreases leukocyte trafficking and peritonitis.

J Pharmacol Exp Ther 2005 Jul 18;314(1):155-61. Epub 2005 Mar 18.

Department of Comparative Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1124/jpet.104.082529DOI Listing
July 2005

Regulation of platelet granule exocytosis by S-nitrosylation.

Proc Natl Acad Sci U S A 2005 Mar 28;102(10):3782-7. Epub 2005 Feb 28.

Department of Comparative Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0408310102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC553307PMC
March 2005

A novel class of fusion polypeptides inhibits exocytosis.

Mol Pharmacol 2005 Apr 17;67(4):1137-44. Epub 2004 Dec 17.

Department of Medicine, The Johns Hopkins University School of Medicine, 950 Ross Building, 720 Rutland Avenue, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1124/mol.104.004275DOI Listing
April 2005

Rac1 regulates the release of Weibel-Palade Bodies in human aortic endothelial cells.

Chin Med J (Engl) 2004 Aug;117(8):1143-50

Cardiovascular Center, Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China.

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August 2004

Exogenous thioredoxin reduces inflammation in autoimmune myocarditis.

Circulation 2004 Sep;110(10):1178-9

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http://dx.doi.org/10.1161/01.CIR.0000143048.05940.0DDOI Listing
September 2004

Peroxynitrite inhibition of Coxsackievirus infection by prevention of viral RNA entry.

Proc Natl Acad Sci U S A 2004 Aug 30;101(32):11731-6. Epub 2004 Jul 30.

Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0400518101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC511044PMC
August 2004

Sphingosine 1-phosphate activates Weibel-Palade body exocytosis.

Proc Natl Acad Sci U S A 2004 Aug 23;101(31):11483-7. Epub 2004 Jul 23.

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.0400185101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC509226PMC
August 2004

Ceramide triggers Weibel-Palade body exocytosis.

Circ Res 2004 Aug 24;95(3):319-24. Epub 2004 Jun 24.

Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Md 21205, USA.

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http://dx.doi.org/10.1161/01.RES.0000136519.84279.7aDOI Listing
August 2004

iNOS (NOS2) at a glance.

J Cell Sci 2004 Jun;117(Pt 14):2865-7

Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1242/jcs.01166DOI Listing
June 2004

L-arginine ameliorates the abnormal sympathetic response of the dysfunctional human coronary microvasculature.

Angiology 2004 Jan-Feb;55(1):1-8

Department of Internal Medicine, Division of Cardiology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/000331970405500101DOI Listing
February 2004

Nitric oxide inhibits the adenovirus proteinase in vitro and viral infectivity in vivo.

FASEB J 2003 Dec 2;17(15):2345-6. Epub 2003 Oct 2.

Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1096/fj.03-0396fjeDOI Listing
December 2003

Inducible nitric oxide synthase expression inhibition by adenovirus E1A.

Proc Natl Acad Sci U S A 2003 Jun 13;100(13):7773-8. Epub 2003 Jun 13.

Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.1337185100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC164663PMC
June 2003

Measuring reactive oxygen species inhibition of endothelin-converting enzyme.

Methods Enzymol 2002 ;353:263-8

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)53054-8DOI Listing
August 2002

Purification and assessment of proteins associated with nitric oxide synthase.

Methods Enzymol 2002 ;353:233-40

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1016/s0076-6879(02)53051-2DOI Listing
August 2002

TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells.

Am J Physiol Cell Physiol 2002 Jul;283(1):C327-37

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1152/ajpcell.00442.2001DOI Listing
July 2002