Charles Gu

Charles Gu

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Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.

Authors:
Paul S de Vries Michael R Brown Amy R Bentley Yun J Sung Thomas W Winkler Ioanna Ntalla Karen Schwander Aldi T Kraja Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Xuan Deng Rajkumar Dorajoo Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Evangelos Evangelou Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Joseph H Lee Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Muhammad Riaz M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Yajuan Wang Erin B Ware Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Christie Ballantyne Eric Boerwinkle Ulrich Broeckel Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Ulf de Faire Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Jingzhong Ding Anna F Dominiczak Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul Virginia Fisher Terrence Forrester Oscar H Franco Yechiel Friedlander Mohsen Ghanbari Franco Giulianini Hans J Grabe Megan L Grove C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson Barbara V Howard M Arfan Ikram David R Jacobs Craig Johnson Jost Bruno Jonas Candace M Kammerer Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Heikki A Koistinen Ivana Kolcic Charles Kooperberg Jose E Krieger Steve B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Rozenn N Lemaitre Yize Li Jingjing Liang Jianjun Liu Kiang Liu Marie Loh Tin Louie Reedik Mägi Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Thomas H Mosley Kenneth J Mukamal Mike A Nalls Matthias Nauck Christopher P Nelson Nona Sotoodehnia Jeff R O'Connell Nicholette D Palmer Raha Pazoki Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Leslie J Raffel Olli T Raitakari Alex P Reiner Treva K Rice Stephen S Rich Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Nicholas Tan Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Diana van Heemst Dragana Vuckovic Melanie Waldenberger Lihua Wang Yujie Wang Zhe Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Markku Laakso Karin Leander Terho Lehtimäki Patrik K E Magnusson Brenda Penninx Alexandre C Pereira Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Wei Zheng Paul Elliott Kari E North Claude Bouchard Michele K Evans Vilmundur Gudnason Ching-Ti Liu Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Sharon L R Kardia Xiaofeng Zhu Charles N Rotimi Dennis O Mook-Kanamori Myriam Fornage Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Jingmin Liu Jerome I Rotter W James Gauderman Michael A Province Patricia B Munroe Kenneth Rice Daniel I Chasman L Adrienne Cupples Dabeeru C Rao Alanna C Morrison

Am J Epidemiol 2019 Jun;188(6):1033-1054

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas.

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https://academic.oup.com/aje/advance-article/doi/10.1093/aje
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http://dx.doi.org/10.1093/aje/kwz005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545280PMC
June 2019

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.

Authors:
Amy R Bentley Yun J Sung Michael R Brown Thomas W Winkler Aldi T Kraja Ioanna Ntalla Karen Schwander Daniel I Chasman Elise Lim Xuan Deng Xiuqing Guo Jingmin Liu Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jennifer E Huffman Solomon K Musani Changwei Li Mary F Feitosa Melissa A Richard Raymond Noordam Jenna Baker Guanjie Chen Hugues Aschard Traci M Bartz Jingzhong Ding Rajkumar Dorajoo Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Wei Zhao Mariaelisa Graff Maris Alver Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Evangelos Evangelou Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Yi-Jen Hung Anne U Jackson Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Nana Matoba Ilja M Nolte Maik Pietzner Bram Prins Muhammad Riaz Antonietta Robino M Abdullah Said Nicole Schupf Robert A Scott Tamar Sofer Alena Stancáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Tzung-Dau Wang Yajuan Wang Erin B Ware Wanqing Wen Yong-Bing Xiang Lisa R Yanek Weihua Zhang Jing Hua Zhao Adebowale Adeyemo Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Zorayr Arzumanyan Tin Aung Christie Ballantyne R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Ulrich Broeckel Morris Brown Brian E Cade Archie Campbell Mickaël Canouil Sabanayagam Charumathi Yii-Der Ida Chen Kaare Christensen Maria Pina Concas John M Connell Lisa de Las Fuentes H Janaka de Silva Paul S de Vries Ayo Doumatey Qing Duan Charles B Eaton Ruben N Eppinga Jessica D Faul James S Floyd Nita G Forouhi Terrence Forrester Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Sina A Gharib Bruna Gigante Franco Giulianini Hans J Grabe C Charles Gu Tamara B Harris Sami Heikkinen Chew-Kiat Heng Makoto Hirata James E Hixson M Arfan Ikram Yucheng Jia Roby Joehanes Craig Johnson Jost Bruno Jonas Anne E Justice Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Ivana Kolcic Charles Kooperberg Jose E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Jingjing Liang Shiow Lin Ching-Ti Liu Jianjun Liu Kiang Liu Marie Loh Kurt K Lohman Tin Louie Anna Luzzi Reedik Mägi Anubha Mahajan Ani W Manichaikul Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Andrew P Morris Alison D Murray Mike A Nalls Matthias Nauck Christopher P Nelson Kari E North Jeffrey R O'Connell Nicholette D Palmer George J Papanicolau Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Neil Poulter Olli T Raitakari Alex P Reiner Frida Renström Treva K Rice Stephen S Rich Jennifer G Robinson Lynda M Rose Frits R Rosendaal Igor Rudan Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Yuan Shi Stephen Sidney Mario Sims Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Henning Tiemeier Stephen T Turner André G Uitterlinden Diana van Heemst Melanie Waldenberger Heming Wang Lan Wang Lihua Wang Wen Bin Wei Christine A Williams Gregory Wilson Mary K Wojczynski Jie Yao Kristin Young Caizheng Yu Jian-Min Yuan Jie Zhou Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Richard S Cooper Ulf de Faire Ian J Deary Paul Elliott Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo L Horta Jyh-Ming Jimmy Juang Yoichiro Kamatani Candace M Kammerer Norihiro Kato Jaspal S Kooner Markku Laakso Cathy C Laurie I-Te Lee Terho Lehtimäki Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Alexandre C Pereira Rainer Rauramaa Susan Redline Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Jun-Sing Wang Ya Xing Wang Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Eleftheria Zeggini Wei Zheng Claude Bouchard Michele K Evans Vilmundur Gudnason Sharon L R Kardia Yongmei Liu Bruce M Psaty Paul M Ridker Rob M van Dam Dennis O Mook-Kanamori Myriam Fornage Michael A Province Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Nora Franceschini Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Kenneth Rice Patricia B Munroe Alanna C Morrison Dabeeru C Rao Charles N Rotimi L Adrienne Cupples

Nat Genet 2019 04 29;51(4):636-648. Epub 2019 Mar 29.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41588-019-0378-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467258PMC
April 2019

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Authors:
Yun Ju Sung Lisa de Las Fuentes Thomas W Winkler Daniel I Chasman Amy R Bentley Aldi T Kraja Ioanna Ntalla Helen R Warren Xiuqing Guo Karen Schwander Alisa K Manning Michael R Brown Hugues Aschard Mary F Feitosa Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Tuomas O Kilpeläinen Melissa A Richard Stella Aslibekyan Traci M Bartz Rajkumar Dorajoo Changwei Li Yongmei Liu Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Candace M Kammerer Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Colin A McKenzie Christopher P Nelson Raymond Noordam Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Robert J Waken Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan E Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Brian Cade Archie Campbell Mickaël Canouil Aravinda Chakravarti Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante C Charles Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Albert Hofman Barbara V Howard Steven C Hunt Marguerite R Irvin Yucheng Jia Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Charles B Kooperberg Jose E Krieger Michiaki Kubo Zoltan Kutalik Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Joseph H Lee Benjamin Lehne Daniel Levy Cora E Lewis Yize Li Sing Hui Lim Ching-Ti Liu Jianjun Liu Jingmin Liu Yeheng Liu Marie Loh Kurt K Lohman Tin Louie Reedik Mägi Koichi Matsuda Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Thomas H Mosley Mike A Nalls Ubaydah Nasri Jeff R O'Connell Adesola Ogunniyi Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David Porteous Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Mario Sims Colleen M Sitlani Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Gregory Wilson Mary K Wojczynski Yong-Bing Xiang Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen David R Weir Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost Bruno Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Albertine J Oldehinkel Alexandre C Pereira Thomas Perls Rainer Rauramaa Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins Ananda R Wickremasinghe Tangchun Wu Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason James Hixson Sharon L R Kardia Stephen B Kritchevsky Bruce M Psaty Rob M van Dam Donna K Arnett Dennis O Mook-Kanamori Myriam Fornage Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Charles N Rotimi Laura J Bierut Xiaofeng Zhu L Adrienne Cupples Michael A Province Jerome I Rotter Paul W Franks Kenneth Rice Paul Elliott Mark J Caulfield W James Gauderman Patricia B Munroe Dabeeru C Rao Alanna C Morrison

Hum Mol Genet 2019 Apr 10. Epub 2019 Apr 10.

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.

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https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg
Publisher Site
http://dx.doi.org/10.1093/hmg/ddz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644157PMC
April 2019

Uncovering the complex genetics of human personality: response from authors on the PGMRA Model.

Mol Psychiatry 2019 Mar 18. Epub 2019 Mar 18.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41380-019-0399-zDOI Listing
March 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

PLoS One 2018 18;13(6):e0198166. Epub 2018 Jun 18.

The Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198166PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005576PMC
January 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 Jan 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

Authors:
Yun J Sung Thomas W Winkler Lisa de Las Fuentes Amy R Bentley Michael R Brown Aldi T Kraja Karen Schwander Ioanna Ntalla Xiuqing Guo Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Mary F Feitosa Tuomas O Kilpeläinen Melissa A Richard Raymond Noordam Stella Aslibekyan Hugues Aschard Traci M Bartz Rajkumar Dorajoo Yongmei Liu Alisa K Manning Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Helen R Warren Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando Pires Hartwig Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian 'an Luan Colin A McKenzie He Meian Christopher P Nelson Rainer Rauramaa Nicole Schupf Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Claudia P Cabrera Brian Cade Yu Caizheng Archie Campbell Mickaël Canouil Aravinda Chakravarti Ganesh Chauhan Kaare Christensen Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Stephanie Debette Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Virginia A Fisher Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante Misa Graff C Charles Gu Dongfeng Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Albert Hofman Barbara V Howard Steven Hunt Marguerite R Irvin Yucheng Jia Roby Joehanes Anne E Justice Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Pirjo Komulainen Charles Kooperberg Jose E Krieger Michiaki Kubo Johanna Kuusisto Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Sing Hui Lim Shiow Lin Ching-Ti Liu Jianjun Liu Jingmin Liu Kiang Liu Yeheng Liu Marie Loh Kurt K Lohman Jirong Long Tin Louie Reedik Mägi Anubha Mahajan Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Andrew P Morris Thomas H Mosley Peter Munson Alison D Murray Mike A Nalls Ubaydah Nasri Jill M Norris Kari North Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Sudha Seshadri Peter Sever Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya X Wang Wen Bin Wei Christine Williams Gregory Wilson Mary K Wojczynski Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost B Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Anne B Newman Albertine J Oldehinkel Alexandre C Pereira Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason Sharon L R Kardia Stephen B Kritchevsky Daniel Levy Jeff R O'Connell Bruce M Psaty Rob M van Dam Mario Sims Donna K Arnett Dennis O Mook-Kanamori Tanika N Kelly Ervin R Fox Caroline Hayward Myriam Fornage Charles N Rotimi Michael A Province Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Jerome I Rotter Xiaofeng Zhu Laura J Bierut W James Gauderman Mark J Caulfield Paul Elliott Kenneth Rice Patricia B Munroe Alanna C Morrison L Adrienne Cupples Dabeeru C Rao Daniel I Chasman

Am J Hum Genet 2018 03 15;102(3):375-400. Epub 2018 Feb 15.

Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985266PMC
March 2018

Blood Pressure Genetic Risk Score Predicts Blood Pressure Responses to Dietary Sodium and Potassium: The GenSalt Study (Genetic Epidemiology Network of Salt Sensitivity).

Hypertension 2017 12 9;70(6):1106-1112. Epub 2017 Oct 9.

From the Department of Epidemiology (J.L.N., C.L., J.H., T.N.K.) and Department of Medicine (J.H.), Tulane University School of Public Health and Tropical Medicine, New Orleans, LA; Department of Epidemiology and Biostatistics, University of Georgia College of Public Health, Athens (C.L.); Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (D.G., J.C., X.L., J.L., X.W.); Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston (J.E.H.); and Division of Biostatistics, Washington University School of Medicine, St. Louis, MO (C.C.G., D.C.R.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443381PMC
December 2017

Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry.

J Hypertens 2017 07;35(7):1381-1389

aMcKusick-Nathans Institute of Genetic Medicine bPredoctoral Training Program in Human Genetics and Molecular Biology, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland cBrown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas dCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland eDepartment of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois fDepartment of Epidemiology gInstitute for Social Research, University of Michigan, Ann Arbor, Michigan hDivision of Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA iDepartment of Medicine, University of Ibadan, Ibadan, Nigeria jHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA kDepartment of Specialties of Medicine, Geneva University Hospital, Geneva, Switzerland.

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http://dx.doi.org/10.1097/HJH.0000000000001319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451310PMC
July 2017

Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.

Hum Genet 2017 06 8;136(6):771-800. Epub 2017 Apr 8.

Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1007/s00439-017-1787-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485655PMC
June 2017

Associations Between Genetic Variants of NADPH Oxidase-Related Genes and Blood Pressure Responses to Dietary Sodium Intervention: The GenSalt Study.

Am J Hypertens 2017 Apr;30(4):427-434

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1093/ajh/hpw200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191854PMC
April 2017

Associations of Variants in the CACNA1A and CACNA1C Genes With Longitudinal Blood Pressure Changes and Hypertension Incidence: The GenSalt Study.

Am J Hypertens 2016 11;29(11):1301-1306

Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055736PMC
http://dx.doi.org/10.1093/ajh/hpw070DOI Listing
November 2016

Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study.

Hypertension 2016 08 6;68(2):348-55. Epub 2016 Jun 6.

From the Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (C.L., J.H., J.Z., T.N.K.); Department of Medicine, Tulane University School of Medicine, New Orleans, LA (J.H., J.C.); State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (D.G., J.C., J.H., S.C.); Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston (J.E.H.); Division of Biostatistics, Washington University School of Medicine, St. Louis, MO (D.C.R., C.C.G.); and Division of Prevention and Population Sciences, National Heart, Lung, Blood Institute, Bethesda, MD (C.E.J.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.06765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373034PMC
August 2016

Associations Between Genetic Variants of the Natriuretic Peptide System and Blood Pressure Response to Dietary Sodium Intervention: The GenSalt Study.

Am J Hypertens 2016 Mar 29;29(3):397-404. Epub 2015 Jul 29.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China;

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http://dx.doi.org/10.1093/ajh/hpv129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757957PMC
March 2016

Genetic association of left ventricular mass assessed by M-mode and two-dimensional echocardiography.

J Hypertens 2016 Jan;34(1):88-96

aDivision of Biostatistics bDepartment of Genetics cCardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1097/HJH.0000000000000765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410384PMC
January 2016

Directional dominance on stature and cognition in diverse human populations.

Authors:
Peter K Joshi Tonu Esko Hannele Mattsson Niina Eklund Ilaria Gandin Teresa Nutile Anne U Jackson Claudia Schurmann Albert V Smith Weihua Zhang Yukinori Okada Alena Stančáková Jessica D Faul Wei Zhao Traci M Bartz Maria Pina Concas Nora Franceschini Stefan Enroth Veronique Vitart Stella Trompet Xiuqing Guo Daniel I Chasman Jeffery R O'Connel Tanguy Corre Suraj S Nongmaithem Yuning Chen Massimo Mangino Daniela Ruggiero Michela Traglia Aliki-Eleni Farmaki Tim Kacprowski Andrew Bjonnes Ashley van der Spek Ying Wu Anil K Giri Lisa R Yanek Lihua Wang Edith Hofer Cornelius A Rietveld Olga McLeod Marilyn C Cornelis Cristian Pattaro Niek Verweij Clemens Baumbach Abdel Abdellaoui Helen R Warren Dragana Vuckovic Hao Mei Claude Bouchard John R B Perry Stefania Cappellani Saira S Mirza Miles C Benton Ulrich Broeckel Sarah E Medland Penelope A Lind Giovanni Malerba Alexander Drong Loic Yengo Lawrence F Bielak Degui Zhi Peter J van der Most Daniel Shriner Reedik Mägi Gibran Hemani Tugce Karaderi Zhaoming Wang Tian Liu Ilja Demuth Jing Hua Zhao Weihua Meng Lazaros Lataniotis Sander W van der Laan Jonathan P Bradfield Andrew R Wood Amelie Bonnefond Tarunveer S Ahluwalia Leanne M Hall Erika Salvi Seyhan Yazar Lisbeth Carstensen Hugoline G de Haan Mark Abney Uzma Afzal Matthew A Allison Najaf Amin Folkert W Asselbergs Stephan J L Bakker R Graham Barr Sebastian E Baumeister Daniel J Benjamin Sven Bergmann Eric Boerwinkle Erwin P Bottinger Archie Campbell Aravinda Chakravarti Yingleong Chan Stephen J Chanock Constance Chen Y-D Ida Chen Francis S Collins John Connell Adolfo Correa L Adrienne Cupples George Davey Smith Gail Davies Marcus Dörr Georg Ehret Stephen B Ellis Bjarke Feenstra Mary F Feitosa Ian Ford Caroline S Fox Timothy M Frayling Nele Friedrich Frank Geller Generation Scotland Irina Gillham-Nasenya Omri Gottesman Misa Graff Francine Grodstein Charles Gu Chris Haley Christopher J Hammond Sarah E Harris Tamara B Harris Nicholas D Hastie Nancy L Heard-Costa Kauko Heikkilä Lynne J Hocking Georg Homuth Jouke-Jan Hottenga Jinyan Huang Jennifer E Huffman Pirro G Hysi M Arfan Ikram Erik Ingelsson Anni Joensuu Åsa Johansson Pekka Jousilahti J Wouter Jukema Mika Kähönen Yoichiro Kamatani Stavroula Kanoni Shona M Kerr Nazir M Khan Philipp Koellinger Heikki A Koistinen Manraj K Kooner Michiaki Kubo Johanna Kuusisto Jari Lahti Lenore J Launer Rodney A Lea Benjamin Lehne Terho Lehtimäki David C M Liewald Lars Lind Marie Loh Marja-Liisa Lokki Stephanie J London Stephanie J Loomis Anu Loukola Yingchang Lu Thomas Lumley Annamari Lundqvist Satu Männistö Pedro Marques-Vidal Corrado Masciullo Angela Matchan Rasika A Mathias Koichi Matsuda James B Meigs Christa Meisinger Thomas Meitinger Cristina Menni Frank D Mentch Evelin Mihailov Lili Milani May E Montasser Grant W Montgomery Alanna Morrison Richard H Myers Rajiv Nadukuru Pau Navarro Mari Nelis Markku S Nieminen Ilja M Nolte George T O'Connor Adesola Ogunniyi Sandosh Padmanabhan Walter R Palmas James S Pankow Inga Patarcic Francesca Pavani Patricia A Peyser Kirsi Pietilainen Neil Poulter Inga Prokopenko Sarju Ralhan Paul Redmond Stephen S Rich Harri Rissanen Antonietta Robino Lynda M Rose Richard Rose Cinzia Sala Babatunde Salako Veikko Salomaa Antti-Pekka Sarin Richa Saxena Helena Schmidt Laura J Scott William R Scott Bengt Sennblad Sudha Seshadri Peter Sever Smeeta Shrestha Blair H Smith Jennifer A Smith Nicole Soranzo Nona Sotoodehnia Lorraine Southam Alice V Stanton Maria G Stathopoulou Konstantin Strauch Rona J Strawbridge Matthew J Suderman Nikhil Tandon Sian-Tsun Tang Kent D Taylor Bamidele O Tayo Anna Maria Töglhofer Maciej Tomaszewski Natalia Tšernikova Jaakko Tuomilehto Andre G Uitterlinden Dhananjay Vaidya Astrid van Hylckama Vlieg Jessica van Setten Tuula Vasankari Sailaja Vedantam Efthymia Vlachopoulou Diego Vozzi Eero Vuoksimaa Melanie Waldenberger Erin B Ware William Wentworth-Shields John B Whitfield Sarah Wild Gonneke Willemsen Chittaranjan S Yajnik Jie Yao Gianluigi Zaza Xiaofeng Zhu The BioBank Japan Project Rany M Salem Mads Melbye Hans Bisgaard Nilesh J Samani Daniele Cusi David A Mackey Richard S Cooper Philippe Froguel Gerard Pasterkamp Struan F A Grant Hakon Hakonarson Luigi Ferrucci Robert A Scott Andrew D Morris Colin N A Palmer George Dedoussis Panos Deloukas Lars Bertram Ulman Lindenberger Sonja I Berndt Cecilia M Lindgren Nicholas J Timpson Anke Tönjes Patricia B Munroe Thorkild I A Sørensen Charles N Rotimi Donna K Arnett Albertine J Oldehinkel Sharon L R Kardia Beverley Balkau Giovanni Gambaro Andrew P Morris Johan G Eriksson Margie J Wright Nicholas G Martin Steven C Hunt John M Starr Ian J Deary Lyn R Griffiths Henning Tiemeier Nicola Pirastu Jaakko Kaprio Nicholas J Wareham Louis Pérusse James G Wilson Giorgia Girotto Mark J Caulfield Olli Raitakari Dorret I Boomsma Christian Gieger Pim van der Harst Andrew A Hicks Peter Kraft Juha Sinisalo Paul Knekt Magnus Johannesson Patrik K E Magnusson Anders Hamsten Reinhold Schmidt Ingrid B Borecki Erkki Vartiainen Diane M Becker Dwaipayan Bharadwaj Karen L Mohlke Michael Boehnke Cornelia M van Duijn Dharambir K Sanghera Alexander Teumer Eleftheria Zeggini Andres Metspalu Paolo Gasparini Sheila Ulivi Carole Ober Daniela Toniolo Igor Rudan David J Porteous Marina Ciullo Tim D Spector Caroline Hayward Josée Dupuis Ruth J F Loos Alan F Wright Giriraj R Chandak Peter Vollenweider Alan Shuldiner Paul M Ridker Jerome I Rotter Naveed Sattar Ulf Gyllensten Kari E North Mario Pirastu Bruce M Psaty David R Weir Markku Laakso Vilmundur Gudnason Atsushi Takahashi John C Chambers Jaspal S Kooner David P Strachan Harry Campbell Joel N Hirschhorn Markus Perola Ozren Polašek James F Wilson

Nature 2015 Jul 1;523(7561):459-462. Epub 2015 Jul 1.

Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.

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http://dx.doi.org/10.1038/nature14618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516141PMC
July 2015

A custom correlation coefficient (CCC) approach for fast identification of multi-SNP association patterns in genome-wide SNPs data.

Genet Epidemiol 2014 Nov 28;38(7):610-21. Epub 2014 Aug 28.

Division of Biostatistics, Washington University School of Medicine, Missouri, United States of America; Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Department of Medicine, Washington University School of Medicine, Missouri, United States of America; Current address: Sharlee Climer, Department of Computer Science and Engineering, Washington University School of Engineering, Missouri, United States of America.

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http://dx.doi.org/10.1002/gepi.21833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190009PMC
November 2014

Interplay of genetic risk (CHRNA5) and environmental risk (partner smoking) on cigarette smoking reduction.

Drug Alcohol Depend 2014 Oct 3;143:36-43. Epub 2014 Jul 3.

Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2014.06.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161618PMC
October 2014

Random forest fishing: a novel approach to identifying organic group of risk factors in genome-wide association studies.

Eur J Hum Genet 2014 Feb 22;22(2):254-9. Epub 2013 May 22.

1] Division of Biostatistics, Washington University School of Medicine, St Louis, MO, USA [2] Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1038/ejhg.2013.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895629PMC
February 2014

A whole-genome simulator capable of modeling high-order epistasis for complex disease.

Genet Epidemiol 2013 Nov 1;37(7):686-94. Epub 2013 Oct 1.

Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1002/gepi.21761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143152PMC
November 2013

Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets.

Eur J Hum Genet 2012 Nov 18;20(11):1168-73. Epub 2012 Apr 18.

Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1038/ejhg.2012.66DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477866PMC
November 2012

Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance.

Cell Metab 2012 Nov 25;16(5):658-64. Epub 2012 Oct 25.

Center for Human Nutrition and Atkins Center of Excellence in Obesity Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131120039
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http://dx.doi.org/10.1016/j.cmet.2012.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496026PMC
November 2012

Genotype imputation for African Americans using data from HapMap phase II versus 1000 genomes projects.

Genet Epidemiol 2012 Jul 29;36(5):508-16. Epub 2012 May 29.

Division of Biostatistics, Washington University in St. Louis, School of Medicine, St. Louis, Missouri 63110-1093, USA.

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http://doi.wiley.com/10.1002/gepi.21647
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http://dx.doi.org/10.1002/gepi.21647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703942PMC
July 2012

Characterization of autosomal copy-number variation in African Americans: the HyperGEN Study.

Eur J Hum Genet 2011 Dec 15;19(12):1271-5. Epub 2011 Jun 15.

Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1038/ejhg.2011.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230358PMC
December 2011

Enrichment analysis of genetic association in genes and pathways by aggregating signals from both rare and common variants.

BMC Proc 2011 Nov 29;5 Suppl 9:S52. Epub 2011 Nov 29.

Division of Biostatistics, Washington University School of Medicine, Box 8067, 660 South Euclid Avenue, St, Louis, MO 63110, USA.

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http://dx.doi.org/10.1186/1753-6561-5-S9-S52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287890PMC
November 2011

Variable set enrichment analysis in genome-wide association studies.

Eur J Hum Genet 2011 Aug 23;19(8):893-900. Epub 2011 Mar 23.

Division of Biostatistics, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1038/ejhg.2011.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172928PMC
August 2011

Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families.

Circ Res 2011 Feb 6;108(3):279-83. Epub 2011 Jan 6.

Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, RPHB 220E, 1530 3rd Ave South, Birmingham, AL 35294-0022, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.110.239210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328104PMC
February 2011

Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS.

Genet Epidemiol 2011 Feb 31;35(2):111-8. Epub 2010 Dec 31.

Division of Biostatistics, Washington University School of Medicine, Saint Louis, Missouri 63110-1093, USA.

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http://doi.wiley.com/10.1002/gepi.20556
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http://dx.doi.org/10.1002/gepi.20556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624896PMC
February 2011

Genetic variants in the renin-angiotensin system and blood pressure reactions to the cold pressor test.

J Hypertens 2010 Dec;28(12):2422-8

Department of Evidence Based Medicine and Division of Population Genetics, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1097/HJH.0b013e32833ea74eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029492PMC
December 2010

NOD2 status and human ileal gene expression.

Inflamm Bowel Dis 2010 Oct;16(10):1649-57

Division of Gastroenterology, Washington University, St Louis School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1002/ibd.21208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4002261PMC
October 2010

Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure.

J Hypertens 2010 Jun;28(6):1210-20

Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Chinese National Center for Cardiovascular Disease Control and Research, Beijing, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884148PMC
June 2010

Association and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic function.

BMC Med Genet 2010 Apr 28;11:65. Epub 2010 Apr 28.

Cardiovascular Division, Department of Medicine, Cardiovascular Imaging and Clinical Research Core Laboratory, Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1186/1471-2350-11-65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874543PMC
April 2010

Comparison between single-marker analysis using Merlin and multi-marker analysis using LASSO for Framingham simulated data.

BMC Proc 2009 Dec 15;3 Suppl 7:S27. Epub 2009 Dec 15.

Division of Biostatistics, Washington University School of Medicine, 660 South Euclid Avenue, Box 8067, St, Louis, Missouri 63110-1093, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795924PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s27DOI Listing
December 2009

Genome-wide association analysis of Framingham Heart Study data for the Genetics Analysis Workshop 16: effects due to medication use.

BMC Proc 2009 Dec 15;3 Suppl 7:S52. Epub 2009 Dec 15.

Division of Biostatistics, Washington University School of Medicine, Box 8067, 660 South Euclid Avenue, St Louis, Missouri 63110 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795952PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s52DOI Listing
December 2009

Combining least absolute shrinkage and selection operator (LASSO) and principal-components analysis for detection of gene-gene interactions in genome-wide association studies.

BMC Proc 2009 Dec 15;3 Suppl 7:S62. Epub 2009 Dec 15.

Division of Biostatistics, Washington University School of Medicine, 660 South Euclid Avenue, St, Louis, Missouri 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795963PMC
http://dx.doi.org/10.1186/1753-6561-3-s7-s62DOI Listing
December 2009

Selection of important variables by statistical learning in genome-wide association analysis.

BMC Proc 2009 Dec 15;3 Suppl 7:S70. Epub 2009 Dec 15.

Division of Biostatistics, Washington University School of Medicine, 660 South Euclid Avenue, St, Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1186/1753-6561-3-s7-s70DOI Listing
December 2009

Genetic association analysis of coronary heart disease by profiling gene-environment interaction based on latent components in longitudinal endophenotypes.

BMC Proc 2009 Dec 15;3 Suppl 7:S86. Epub 2009 Dec 15.

Division of Biostatistics, Washington University School of Medicine, 660 South Euclid Avenue, Box 8067, St, Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1186/1753-6561-3-s7-s86DOI Listing
December 2009

Heritability of blood pressure responses to cold pressor test in a Chinese population.

Am J Hypertens 2009 Oct 6;22(10):1096-100. Epub 2009 Aug 6.

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.

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http://dx.doi.org/10.1038/ajh.2009.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896683PMC
October 2009

Admixture mapping of quantitative trait loci for BMI in African Americans: evidence for loci on chromosomes 3q, 5q, and 15q.

Obesity (Silver Spring) 2009 Jun 19;17(6):1226-31. Epub 2009 Feb 19.

Institute for Human Genetics, Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929755PMC
June 2009

Genome-wide distribution of ancestry in Mexican Americans.

Hum Genet 2008 Oct 28;124(3):207-14. Epub 2008 Aug 28.

Institute for Human Genetics, University of California, San Francisco, 513 Parnassus Ave., Room 901H HSW, San Francisco, CA 94143, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131689PMC
October 2008

Enhanced detection of genetic association of hypertensive heart disease by analysis of latent phenotypes.

Genet Epidemiol 2008 Sep;32(6):528-38

Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://doi.wiley.com/10.1002/gepi.20326
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September 2008

Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness.

J Am Soc Echocardiogr 2008 Aug 11;21(8):954-60. Epub 2008 Apr 11.

Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.echo.2008.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536614PMC
August 2008

Risk factors for surgical recurrence after ileocolic resection of Crohn's disease.

Dis Colon Rectum 2008 Aug 7;51(8):1211-6. Epub 2008 Jun 7.

Department of Medicine, Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1007/s10350-008-9348-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580671PMC
August 2008

Characterization of LD structures and the utility of HapMap in genetic association studies.

Adv Genet 2008 ;60:407-35

Division of Biostatistics and Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/S0065-2660(07)00415-4DOI Listing
June 2008

On transferability of genome-wide tagSNPs.

Genet Epidemiol 2008 Feb;32(2):89-97

Division of Biostatistics, Washington University School of Medicine, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1002/gepi.20269DOI Listing
February 2008

Relation of albuminuria to left ventricular mass (from the HyperGEN Study).

Am J Cardiol 2008 Jan;101(2):212-6

Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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January 2008

A novel method combining linkage disequilibrium information and imputed functional knowledge for tagSNP selection.

Hum Hered 2007 22;64(4):243-9. Epub 2007 Jun 22.

Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880730PMC
September 2007

An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (FBPP).

Hum Genet 2007 Jun 20;121(5):577-90. Epub 2007 Mar 20.

Division of Biostatistics, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8067, St Louis, MO 63110, USA.

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June 2007

Measuring marker information content by the ambiguity of block boundaries observed in dense SNP data.

Ann Hum Genet 2007 Jan 8;71(Pt 1):127-40. Epub 2006 Sep 8.

Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA.

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January 2007

Genotype-by-sex interaction on fasting insulin concentration: the HyperGEN study.

Diabetes 2007 Jan;56(1):137-42

Department of Epidemiology, University of North Carolina Chapel Hill, Bank of America Center, 137 E. Franklin St., Suite 306, Chapel Hill, NC 27514, USA.

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January 2007

Haplotype association analysis of AGT variants with hypertension-related traits: the HyperGEN study.

Hum Hered 2005 12;60(3):164-76. Epub 2005 Dec 12.

Division of Biostatistics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.

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September 2006

Global transmission/disequilibrium tests based on haplotype sharing in multiple candidate genes.

Genet Epidemiol 2005 Dec;29(4):323-35

Division of Statistical Genomics, Department of Genetics Washington University, School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/gepi.20102DOI Listing
December 2005

A population association study of angiotensinogen polymorphisms and haplotypes with left ventricular phenotypes.

Hypertension 2005 Dec 14;46(6):1294-9. Epub 2005 Nov 14.

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1161/01.HYP.0000192653.17209.84DOI Listing
December 2005

Admixture mapping for hypertension loci with genome-scan markers.

Nat Genet 2005 Feb 23;37(2):177-81. Epub 2005 Jan 23.

Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, 2160 S. First Ave., Maywood, Illinois 60153, USA.

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February 2005

Power loss for linkage analysis due to the dichotomization of trichotomous phenotypes.

Hum Hered 2004 ;57(1):21-7

Division of Biostatistics, Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.

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November 2004

Genetic association mapping under founder heterogeneity via weighted haplotype similarity analysis in candidate genes.

Genet Epidemiol 2004 Nov;27(3):182-91

Division of Biostatistics, School of Medicine, Washington University, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1002/gepi.20022DOI Listing
November 2004

A variable fold change threshold determines significance for expression microarrays.

FASEB J 2003 Feb 3;17(2):321-3. Epub 2002 Dec 3.

Division of Pulmonary and Critical Care, Department of Medicine, Brigham and Women's Hospital at Harvard Medical School, Boston, Massachusetts 02115, USA.

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February 2003