Charles G Eberhart

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Charles G Eberhart

Publications by authors named "Charles G Eberhart"

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100Publications

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Association of Macular and Peripheral Retinal Macro-Pseudocysts With Chronic Retinal Detachment.

JAMA Ophthalmol 2018 Jun 14. Epub 2018 Jun 14.

Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland.

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June 2018

Concurrent BRAF/MEK Inhibitors in V600-Mutant High-Grade Primary Brain Tumors.

J Natl Compr Canc Netw 2018 Apr;16(4):343-347

Department of Neurology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Department of Pathology, Johns Hopkins University; Department of Radiology and Radiological Science, Johns Hopkins Hospital; and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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April 2018

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.

Dev Cell 2018 03 15;44(6):709-724.e6. Epub 2018 Mar 15.

Center for Neuropathology, Ludwig-Maximilians-University, 81377 Munich, Germany; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, N63 (HPI), Hamburg 20251, Germany; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

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March 2018

Orbital progressive transformation of germinal centers as part of the spectrum of IgG4-related ophthalmic disease: Clinicopathologic features of three cases.

Saudi J Ophthalmol 2018 Jan-Mar;32(1):56-61. Epub 2018 Mar 10.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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March 2018

Primary mesenchymal chondrosarcoma of the orbit: Histopathological report of 3 pediatric cases.

Saudi J Ophthalmol 2018 Jan-Mar;32(1):69-74. Epub 2018 Mar 8.

Pathology and Laboratory Medicine Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

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March 2018

No BRAF V600E Mutation Identified in 28 Periocular Pyogenic Granuloma.

Ophthalmic Plast Reconstr Surg 2018 Feb 5. Epub 2018 Feb 5.

Department of Pathology, First Affiliated Hospital, Dalian Medical University, Dalian, China.

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February 2018

Identifying Corneal Infections in Formalin-Fixed Specimens Using Next Generation Sequencing.

Invest Ophthalmol Vis Sci 2018 Jan;59(1):280-288

Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States.

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January 2018

Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors.

Oncotarget 2018 Jan 3;9(8):8054-8067. Epub 2018 Jan 3.

Hunterian Neurosurgical Research Laboratory, Neurosurgery Department, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD 21231, USA.

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January 2018

Strategies to enhance the distribution of nanotherapeutics in the brain.

J Control Release 2017 Dec 21;267:232-239. Epub 2017 Jul 21.

Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States. Electronic address:

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December 2017

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Dev Cell 2017 12 2;43(6):673-688.e5. Epub 2017 Nov 2.

Department of Developmental Neurobiology, Neurobiology and Brain Tumor Program, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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December 2017

Hemophagocytic Lymphohistiocytosis in Adults with Intraocular Involvement: Clinicopathologic Features of 3 Cases.

Ocul Oncol Pathol 2017 Dec 1;4(1):1-11. Epub 2017 Jun 1.

Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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December 2017

The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity.

Neuro Oncol 2017 Oct;19(10):1361-1371

Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center and Division of Pediatric Oncology and Bloomberg Children's Hospital, Johns Hopkins Hospital, Baltimore, Maryland; St Jude Children's Research Hospital, Memphis, Tennessee.

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October 2017

Delayed Superficial Migration of Retained Hyaluronic Acid Years Following Periocular Injection.

Ophthalmic Plast Reconstr Surg 2017 May/Jun;33(3S Suppl 1):S116-S118

*Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD; and †North Shore Eye Care, Smithtown, NY, U.S.A.

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September 2017

Hypoxia inhibits growth, proliferation, and increases response to chemotherapy in retinoblastoma cells.

Exp Eye Res 2017 09 6;162:48-61. Epub 2017 Jul 6.

Departments of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. Electronic address:

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September 2017

Amide proton transfer-weighted magnetic resonance image-guided stereotactic biopsy in patients with newly diagnosed gliomas.

Eur J Cancer 2017 09 10;83:9-18. Epub 2017 Jul 10.

Department of Radiology, Johns Hopkins University, Baltimore, MD, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA. Electronic address:

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September 2017

Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI.

Magn Reson Med 2017 Sep 16;78(3):1100-1109. Epub 2017 Jul 16.

Division of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.

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September 2017

Melanoma subtypes demonstrate distinct PD-L1 expression profiles.

Lab Invest 2017 09 24;97(9):1063-1071. Epub 2017 Jul 24.

Department of Dermatology, Johns Hopkins University School of Medicine, Bloomberg Kimmel Institute for Cancer Immunotherapy, and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.

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September 2017

An immunocompetent mouse model of human glioblastoma.

Oncotarget 2017 Sep 15;8(37):61072-61082. Epub 2017 May 15.

Russel H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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September 2017

Rabbit Model of Human Gliomas: Implications for Intra-Arterial Drug Delivery.

PLoS One 2017 19;12(1):e0169656. Epub 2017 Jan 19.

Russell H. Morgan Department. of Radiology and Radiological Science, Division of MR Research, Cellular Imaging Section, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.

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August 2017

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.

Cancer Lett 2017 08 25;400:110-116. Epub 2017 Apr 25.

Department of Pathology, Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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August 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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June 2017

The effect of neurosphere culture conditions on the cellular metabolism of glioma cells.

Folia Neuropathol 2015 ;53(3):219-25

Jarek Maciaczyk, PD, Department of Neurosurgery, University Medical Center Düsseldorf, Germany, e-mail:

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December 2016

Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres.

Brain Pathol 2016 11 8;26(6):713-723. Epub 2016 Feb 8.

Department of Pathology, Division of Neuropathology, Johns Hopkins Hospital, Baltimore, MD.

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November 2016

Targeting Notch signaling as a novel therapy for retinoblastoma.

Oncotarget 2016 Oct;7(43):70028-70044

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

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October 2016

The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma.

Cancer Lett 2016 07 18;377(1):55-64. Epub 2016 Apr 18.

Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA; Division of Pediatric Oncology, Johns Hopkins University, Bloomberg Children's Hospital, Room 11379, 1800 Orleans St, Baltimore, MD 21287, USA. Electronic address:

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July 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 Jul 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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July 2016

Differential DNA methylation identified in the blood and retina of AMD patients.

Epigenetics 2015 ;10(8):698-707

a Department of Ophthalmology; Johns Hopkins University; School of Medicine ; Baltimore , MD USA.

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May 2016

EMT-associated factors promote invasive properties of uveal melanoma cells.

Mol Vis 2015 25;21:919-29. Epub 2015 Aug 25.

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD ; Department of Ophthalmology, Johns Hopkins University, School of Medicine, Baltimore, MD ; Department of Oncology, Johns Hopkins University, School of Medicine, Baltimore, MD.

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May 2016

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.

Genes Chromosomes Cancer 2016 May 4;55(5):418-27. Epub 2016 Feb 4.

Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), and Department of Neuropathology University Hospital, Heidelberg, Germany.

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May 2016

Altered gene expression in conjunctival squamous cell carcinoma.

Mod Pathol 2016 05 26;29(5):452-60. Epub 2016 Feb 26.

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

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May 2016

Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells.

Int J Cancer 2016 Mar 13;138(5):1246-55. Epub 2015 Oct 13.

Department of Pathology, Division of Neuropathology, Johns Hopkins Hospital, Baltimore, MD.

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March 2016

Somatic cell transfer of c-Myc and Bcl-2 induces large-cell anaplastic medulloblastomas in mice.

J Neurooncol 2016 Feb 30;126(3):415-24. Epub 2015 Oct 30.

Department of Neurosurgery and Huntsman Cancer Institute, University of Utah School of Medicine, 175 North Medical Drive East, Salt Lake City, UT, 84132, USA.

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February 2016

Divergent clonal selection dominates medulloblastoma at recurrence.

Authors:
A Sorana Morrissy Livia Garzia David J H Shih Scott Zuyderduyn Xi Huang Patryk Skowron Marc Remke Florence M G Cavalli Vijay Ramaswamy Patricia E Lindsay Salomeh Jelveh Laura K Donovan Xin Wang Betty Luu Kory Zayne Yisu Li Chelsea Mayoh Nina Thiessen Eloi Mercier Karen L Mungall Yusanne Ma Kane Tse Thomas Zeng Karey Shumansky Andrew J L Roth Sohrab Shah Hamza Farooq Noriyuki Kijima Borja L Holgado John J Y Lee Stuart Matan-Lithwick Jessica Liu Stephen C Mack Alex Manno K A Michealraj Carolina Nor John Peacock Lei Qin Juri Reimand Adi Rolider Yuan Y Thompson Xiaochong Wu Trevor Pugh Adrian Ally Mikhail Bilenky Yaron S N Butterfield Rebecca Carlsen Young Cheng Eric Chuah Richard D Corbett Noreen Dhalla An He Darlene Lee Haiyan I Li William Long Michael Mayo Patrick Plettner Jenny Q Qian Jacqueline E Schein Angela Tam Tina Wong Inanc Birol Yongjun Zhao Claudia C Faria José Pimentel Sofia Nunes Tarek Shalaby Michael Grotzer Ian F Pollack Ronald L Hamilton Xiao-Nan Li Anne E Bendel Daniel W Fults Andrew W Walter Toshihiro Kumabe Teiji Tominaga V Peter Collins Yoon-Jae Cho Caitlin Hoffman David Lyden Jeffrey H Wisoff James H Garvin Duncan S Stearns Luca Massimi Ulrich Schüller Jaroslav Sterba Karel Zitterbart Stephanie Puget Olivier Ayrault Sandra E Dunn Daniela P C Tirapelli Carlos G Carlotti Helen Wheeler Andrew R Hallahan Wendy Ingram Tobey J MacDonald Jeffrey J Olson Erwin G Van Meir Ji-Yeoun Lee Kyu-Chang Wang Seung-Ki Kim Byung-Kyu Cho Torsten Pietsch Gudrun Fleischhack Stephan Tippelt Young Shin Ra Simon Bailey Janet C Lindsey Steven C Clifford Charles G Eberhart Michael K Cooper Roger J Packer Maura Massimino Maria Luisa Garre Ute Bartels Uri Tabori Cynthia E Hawkins Peter Dirks Eric Bouffet James T Rutka Robert J Wechsler-Reya William A Weiss Lara S Collier Adam J Dupuy Andrey Korshunov David T W Jones Marcel Kool Paul A Northcott Stefan M Pfister David A Largaespada Andrew J Mungall Richard A Moore Nada Jabado Gary D Bader Steven J M Jones David Malkin Marco A Marra Michael D Taylor

Nature 2016 Jan 13;529(7586):351-7. Epub 2016 Jan 13.

Developmental &Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.

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January 2016

Expression of p16 and p53 in Intraepithelial Periocular Sebaceous Carcinoma.

Ocul Oncol Pathol 2015 Dec 18;2(2):71-5. Epub 2015 Sep 18.

The Johns Hopkins University School of Medicine, Baltimore, Md., USA.

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December 2015

ZEB1 Promotes Invasion in Human Fetal Neural Stem Cells and Hypoxic Glioma Neurospheres.

Brain Pathol 2015 Nov 8;25(6):724-32. Epub 2015 Feb 8.

Department of Pathology, Division of Neuropathology, Johns Hopkins Hospital, Baltimore, MD.

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November 2015

Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation.

PLoS One 2014 28;9(8):e105372. Epub 2014 Aug 28.

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America; Department of Ophthalmology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America; Department of Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States of America.

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October 2015

Clinicopathologic implications of NF1 gene alterations in diffuse gliomas.

Hum Pathol 2015 Sep 30;46(9):1323-30. Epub 2015 May 30.

Division of Neuropathology, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD 21231; Sydney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1800 Orleans Street, Baltimore, MD 21231. Electronic address:

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September 2015

Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells.

J Neuropathol Exp Neurol 2015 Sep;74(9):889-900

From the Division of Neuropathology, Department of Pathology, Johns Hopkins Hospital (UDK, MN, CGE); and Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University (MH), Baltimore, Maryland; Anatomical Pathology, St Jude Children Research Hospital, Memphis, Tennessee (BAO); and Department of Neurosurgery, University Medical Center Düsseldorf, Düsseldorf, Germany (UDK, AKS, KK, JM).

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September 2015

Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition.

J Neuropathol Exp Neurol 2015 Aug;74(8):778-90

From the Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center (ICT, MH-C, WB, CGE, EHR) and Division of Pediatric Oncology (ICT, EHR), Johns Hopkins University, Bloomberg Children's Hospital, Baltimore, Maryland; Children's National Medical Center and George Washington University School of Medicine and Health Sciences, Washington, District of Columbia (MK, JN); Department of Neurology and Ophthalmology, Michigan State University, East Lansing (HTC); and Sparrow Health System, Lansing (HTC), Michigan; and Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (KEW).

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August 2015

Prevalence and distribution of VZV in temporal arteries of patients with giant cell arteritis.

Neurology 2015 May 18;84(19):1948-55. Epub 2015 Feb 18.

From the Departments of Neurology (D.G., T.W., N.K., A.H., A.C., A.R., N.B., J.L.B., R.J.C., R.M., M.A.N.), Microbiology (D.G., R.J.C.), Pathology (P.J.B., B.K.), and Ophthalmology (J.L.B., N.M.), University of Colorado School of Medicine, Aurora; Children's Hospital (C.G., J.E.C.), University of Iowa, Iowa City; Arapahoe County Coroner's Office (K.L.-K.), Aurora, CO; Denver Office of the Medical Examiner (D.B.H.), Denver, CO; Department of Pathology (C.G.E.), Johns Hopkins University School of Medicine, Baltimore, MD; A.M. Rywlin Department of Pathology (B.B., R.J.P.), Mount Sinai Medical Center, Miami Beach, FL; Florida International University (B.B., R.J.P.), Miami Beach; Scheie Eye Institute (M.A.T.) and Department of Pathology and Laboratory Medicine (F.F.), University of Pennsylvania, Philadelphia; Texas Oculoplastic Consultants (M.A., E.W., V.D.), Austin; University of Texas, Southwestern - Austin Transitional Year Program (E.W.), Austin; Departments of Pathology and Laboratory Medicine, Ophthalmology, and Visual Sciences (S.R.), University of British Columbia, Vancouver, Canada; Landspitali University Hospital (V.P.), Reykjavik, Iceland; Department of Neurology (L.P.) and Pathological Institute (S.M.), Assaf Harofeh Medical Center, Zerifin, University of Tel Aviv, Israel; Department of Pathology (D.C.), Centre Hospitalier Universitaire du Nord and RECIP, Amiens, France; Institute of Neuropathology (K.K.), University of Duisburg-Essen, Germany; and Department of Neuropathology (W.B.), University Medical Center Gottingen, Germany.

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May 2015

Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain.

Adv Healthc Mater 2015 May 11;4(7):1023-33. Epub 2015 Mar 11.

Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, 400 N. Broadway, Baltimore, MD, 21231, USA.

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May 2015

Genetic profiling by single-nucleotide polymorphism-based array analysis defines three distinct subtypes of orbital meningioma.

Brain Pathol 2015 Mar 21;25(2):193-201. Epub 2014 May 21.

Department of Pathology, Johns Hopkins University, Baltimore, MD; Division of Pathology, Children's National Medical Center, Washington, DC.

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March 2015

Corticosteroid-loaded biodegradable nanoparticles for prevention of corneal allograft rejection in rats.

J Control Release 2015 Mar 8;201:32-40. Epub 2015 Jan 8.

Department of Ophthalmology, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Center for Nanomedicine, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA. Electronic address:

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March 2015

EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.

Nat Commun 2015 Mar 26;6:6576. Epub 2015 Mar 26.

Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda Maryland 20892, USA.

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March 2015

Intraocular tuberculosis presenting as a large anterior chamber mass.

Ocul Immunol Inflamm 2015 Feb 25;23(1):100-1. Epub 2014 Apr 25.

Wilmer Eye Institute , Baltimore, MD , USA.

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February 2015

A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres.

J Neurooncol 2015 Feb 4;121(3):479-87. Epub 2014 Dec 4.

Department of Neurosurgery, School of Medicine, Johns Hopkins University, 1550 Orleans Street, Room 257 CRB2, Baltimore, MD, 21231, USA.

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February 2015

Notch signaling activation in pediatric low-grade astrocytoma.

J Neuropathol Exp Neurol 2015 Feb;74(2):121-31

From the Departments of Pathology (WDB, KCS, IT, ER, CGE, FJR), Neuroscience (KCS, EEB), and Oncology (LM, ER, CGE, FJR), Johns Hopkins University, Baltimore, Maryland; and Department of Neurological Surgery, Case Western Reserve University, Cleveland, Ohio (EEB).

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February 2015

The chromatin-modifying protein HMGA2 promotes atypical teratoid/rhabdoid cell tumorigenicity.

J Neuropathol Exp Neurol 2015 Feb;74(2):177-85

From the Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center (HK, MH-C, MFW, CGE, EHR), Division of Pediatric Oncology (EHR), Johns Hopkins University School of Medicine, Bloomberg Children's Hospital, Baltimore, Maryland; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina (YK, BEW); and Division of Hematology, Oncology, and Blood and Bone Marrow Transplant, Children's Hospital Los Angeles (JX, AE-E); and the University of Southern California (AE-E), Los Angeles, California.

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February 2015

Molecular pathways: not a simple tube--the many functions of blood vessels.

Clin Cancer Res 2015 Jan 29;21(1):18-23. Epub 2014 Jul 29.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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January 2015

Lateral inhibition of Notch signaling in neoplastic cells.

Oncotarget 2015 Jan;6(3):1666-77

Department of Pathology, Johns Hopkins University, Baltimore, MD 21231, Maryland, USA.

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January 2015

Transcript profile of cellular senescence-related genes in Fuchs endothelial corneal dystrophy.

Exp Eye Res 2014 Dec 11;129:13-7. Epub 2014 Oct 11.

The Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, USA. Electronic address:

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December 2014

Mass confusion in a 30-year-old man.

J Neuroophthalmol 2014 Dec;34(4):408-11

Department of Ophthalmology and Visual Sciences (EM, JG), University of Toronto, Toronto, Canada; Department of Neurology (EM), University of Toronto, Toronto, Canada; Department of Ophthalmology (JG), Queen Elizabeth Hospital, Bridgetown, Barbados; and Departments of Pathology (CGE) and Radiology and Radiological Science (AMB), Johns Hopkins Medical Center, Baltimore, Maryland.

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December 2014

SnapShot: Medulloblastoma.

Cancer Cell 2014 Dec;26(6):940-940.e1

Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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December 2014

Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma.

Invest Ophthalmol Vis Sci 2014 Dec 9;55(12):8604-13. Epub 2014 Dec 9.

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States Department of Ophthalmology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States Department of Oncology, Johns Hopkins University, School of Medicine, Baltimore, Maryland, United States.

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December 2014

Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas.

Neuro Oncol 2014 Oct 6;16(10):1408-16. Epub 2014 May 6.

NYU Comprehensive Neurofibromatosis Center, Division of Pediatric Hematology/Oncology, Department of Pediatrics and Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (M.A.K., G.L., A.M., J.C.A.); Division of Oncology, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (M.J.F., A.J.S.); Department of Radiology, NYU Langone Medical Center, New York, New York (S.S.M., M.C.B.); The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland (K.J.C.); Division of Pediatric Neurosurgery, Department of Neurosurgery, NYU Langone Medical Center, New York, New York (J.H.W., D.H.H.); Division of Biostatistics, Department of Population Health and The Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (J.D.G., T.H.); Department of Neurosurgery, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (A.C.R); Division of Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, California (G.D.); German Cancer Research Center and University Hospital, Heidelberg, Germany (D.T.W.J., A.K., S.M.P.); Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, Maryland (C.G.E.); Division of Neuropathology, Department of Pathology, Department of Neurosurgery and Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (D.Z.).

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October 2014

On the origin of 'guttae'.

Br J Ophthalmol 2014 Sep 10;98(9):1308-10. Epub 2014 Jul 10.

Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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September 2014

No increase in IgG4-positive plasma cells in limbal Rosai-Dorfman disease.

Cornea 2014 Aug;33(8):844-7

*Departments of Ophthalmology and †Pathology, Johns Hopkins University School of Medicine, Baltimore, MD; ‡Department of Ophthalmology, King Saud University School of Medicine, Riyadh, Saudi Arabia.

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August 2014

The demethylating agent 5-Aza reduces the growth, invasiveness, and clonogenicity of uveal and cutaneous melanoma.

Invest Ophthalmol Vis Sci 2014 Aug 21;55(10):6178-86. Epub 2014 Aug 21.

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.

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August 2014

Podocalyxin-like protein is expressed in glioblastoma multiforme stem-like cells and is associated with poor outcome.

PLoS One 2013 16;8(10):e75945. Epub 2013 Oct 16.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America ; Johns Hopkins Physical Science Oncology Center and Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, United States of America.

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July 2014

HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells.

Cancer Res 2014 Jun 7;74(11):3168-79. Epub 2014 Apr 7.

Authors' Affiliations: Hugo W. Moser Research Institute at Kennedy Krieger; Departments of Neurology, Neuroscience, Oncology, Neurosurgery, and Pathology, Johns Hopkins School of Medicine; Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; and Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GeorgiaAuthors' Affiliations: Hugo W. Moser Research Institute at Kennedy Krieger; Departments of Neurology, Neuroscience, Oncology, Neurosurgery, and Pathology, Johns Hopkins School of Medicine; Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; and Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia

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June 2014

Notch signaling in prostate cancer: a moving target.

Prostate 2014 Jun 16;74(9):933-45. Epub 2014 Apr 16.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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June 2014

Long interspersed element-1 protein expression is a hallmark of many human cancers.

Am J Pathol 2014 May 6;184(5):1280-6. Epub 2014 Mar 6.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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May 2014

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation.

Oncotarget 2014 May;5(9):2820-6

Department of Radiation Oncology, Johns Hopkins University School of Medicine, Baltimore MD, USA.

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May 2014

Fuchs endothelial corneal dystrophy: a neurodegenerative disorder?

JAMA Ophthalmol 2014 Apr;132(4):377-8

Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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April 2014

DNA mismatch repair defects and microsatellite instability status in periocular sebaceous carcinoma.

Am J Ophthalmol 2014 Mar 7;157(3):640-7.e1-2. Epub 2013 Dec 7.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Ophthalmology, Johns Hopkins University School of Medicine Wilmer Eye Institute, Baltimore, Maryland. Electronic address:

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March 2014

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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March 2014

Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres.

Acta Neuropathol Commun 2014 Mar 31;2:31. Epub 2014 Mar 31.

Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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March 2014

Design and analysis of keratoconus tissue microarrays.

Cornea 2014 Jan;33(1):49-55

*The Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD; †Department of Ophthalmology, Medical University of Graz, Graz, Austria; ‡Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; §Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD; and ¶Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD.

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January 2014

Endothelial cell microRNA expression in human late-onset Fuchs' dystrophy.

Invest Ophthalmol Vis Sci 2014 Jan 9;55(1):216-25. Epub 2014 Jan 9.

The Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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January 2014

Intratarsal keratinous cyst - an emerging entity.

Case Rep Ophthalmol 2013 5;4(3):160-4. Epub 2013 Oct 5.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Md., USA.

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January 2014

5-Fluorouracil for epithelial downgrowth after Descemet stripping automated endothelial keratoplasty.

Cornea 2013 Dec;32(12):1610-2

*Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT; and †Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.

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December 2013

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

Acta Neuropathol 2013 Dec 31;126(6):917-29. Epub 2013 Oct 31.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.

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December 2013

Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target.

Neuro Oncol 2013 Dec 6;15(12):1604-14. Epub 2013 Nov 6.

Corresponding Authors: Fausto J. Rodriguez, MD, Division of Neuropathology, Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21231. Eric H. Raabe, MD, PhD, Division of Neuropathology, Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21231

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December 2013

cMYC expression in infiltrating gliomas: associations with IDH1 mutations, clinicopathologic features and outcome.

J Neurooncol 2013 Nov 11;115(2):249-59. Epub 2013 Aug 11.

Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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November 2013

Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas.

Am J Surg Pathol 2013 Sep;37(9):1357-64

*Laboratory of Pathology †Pediatric Oncology Branch, NCI, NIH, Bethesda ‡Department of Pathology, Division of Neuropathology, Johns Hopkins Hospital, Baltimore, MD §Children's National Medical Center, Research Center for Genetic Medicine, Washington, DC.

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September 2013