Publications by authors named "Charles Eberhart"

100Publications

Chocolate Cysts Associated With Porous Polyethylene Orbital Implants.

Ophthalmic Plast Reconstr Surg 2020 Aug 18. Epub 2020 Aug 18.

Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IOP.0000000000001797DOI Listing
August 2020

Tarsal Epithelial Cysts: Prevalence, Case Series, and Synthesis of Existing Literature.

Ophthalmic Plast Reconstr Surg 2020 Aug 18. Epub 2020 Aug 18.

Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IOP.0000000000001795DOI Listing
August 2020

Sunitinib malate-loaded biodegradable microspheres for the prevention of corneal neovascularization in rats.

J Control Release 2020 Aug 18;327:456-466. Epub 2020 Aug 18.

Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Departments of Pharmaceutics, Virginia Commonwealth University, Richmond, VA 23298, USA; Department of Ophthalmology, Massey Cancer Center, Center for Pharmaceutical Engineering, Institute for Structural Biology, Drug Discovery & Development, Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2020.08.019DOI Listing
August 2020

Response to letter to the editor: "All models are wrong; some models are useful".

Neuro Oncol 2020 Sep;22(9):1406-1407

Department of Pathology, Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noaa137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523438PMC
September 2020

ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection.

Ocul Surf 2020 Jun 13;18(4):537-544. Epub 2020 Jun 13.

Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtos.2020.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293510PMC
June 2020

MEK Inhibition Suppresses Growth of Atypical Teratoid/Rhabdoid Tumors.

J Neuropathol Exp Neurol 2020 Jul;79(7):746-753

Division of Pediatric Oncology, Department of Oncology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnen/nlaa042DOI Listing
July 2020

Spatial enrichment of cellular states in glioblastoma.

Acta Neuropathol 2020 07 24;140(1):85-87. Epub 2020 May 24.

Departments of Pathology and Neurosurgery, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, 655 W. Baltimore St., Bressler Research Bldg., Room 8-039, Baltimore, MD, 21201, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-020-02165-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362280PMC
July 2020

Non-adhesive and highly stable biodegradable nanoparticles that provide widespread and safe transgene expression in orthotopic brain tumors.

Drug Deliv Transl Res 2020 06;10(3):572-581

Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13346-020-00759-8DOI Listing
June 2020

Partial-thickness scleral defect in a congenital scleral epithelial cyst.

J AAPOS 2020 Jun 4;24(3):169-172. Epub 2020 Apr 4.

Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland; Dana Center for Preventive Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Berman Institute of Bioethics, Johns Hopkins University, Baltimore, Maryland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaapos.2020.01.012DOI Listing
June 2020

SWI/SNF complex differences promote cellular heterogeneity in rhabdoid tumors.

Neuro Oncol 2020 06;22(6):741-742

Department of Oncology, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noaa081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283025PMC
June 2020

Increased Tau Expression Correlates With IDH Mutation in Infiltrating Gliomas and Impairs Cell Migration.

J Neuropathol Exp Neurol 2020 May;79(5):493-499

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnen/nlaa013DOI Listing
May 2020

Astrocytes: new stars in the medulloblastoma firmament.

Authors:
Charles Eberhart

Neuro Oncol 2020 05;22(5):587-589

Johns Hopkins University School of Medicine, Departments of Pathology, Oncology, and Ophthalmology.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noaa057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229242PMC
May 2020

Role of anterior segment imaging in the diagnosis of atypical pterygium.

Can J Ophthalmol 2020 06 23;55(3):e115-e117. Epub 2019 Dec 23.

Johns Hopkins University School of Medicine, Baltimore, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcjo.2019.10.009DOI Listing
June 2020

Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity.

Neuro Oncol 2020 04;22(4):563-574

Johns Hopkins School of Medicine, Department of Pathology, Division of Neuropathology, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/noz230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158655PMC
April 2020

Genomic Landscape of Intramedullary Spinal Cord Gliomas.

Sci Rep 2019 12 10;9(1):18722. Epub 2019 Dec 10.

Ludwig Center for Cancer Genetics, Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-54286-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904446PMC
December 2019

PD-L1 Expression in Pediatric Low-Grade Gliomas Is Independent of BRAF V600E Mutational Status.

J Neuropathol Exp Neurol 2020 01;79(1):74-85

Division of Pediatric Oncology, Johns Hopkins School of Medicine, Sidney Kimmel Cancer Center, Baltimore, Maryland (AMM, EHR); Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota (WRB); Department of Pathology, Division of Neuropathology, Johns Hopkins School of Medicine, Baltimore, Maryland (MY, BP, AA, LA, EHR, CGE); Department of Molecular and Cell Biology, The Johns Hopkins University, Krieger School of Arts and Sciences, Baltimore, Maryland (LH); Department of Oncology, Bloomberg-Kimmel Institute for Cancer Immunotherapy (ELE); and Department of Neurosurgery, Division of Neurosurgical Oncology (ML), Johns Hopkins School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnen/nlz119DOI Listing
January 2020

Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor.

Sci Rep 2019 11 29;9(1):17936. Epub 2019 Nov 29.

Nanoelectronics Laboratory, Department of Electrical Engineering and Computer Science, University of Cincinnati, Cincinnati, OH, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-54283-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884550PMC
November 2019

The therapeutic and diagnostic potential of regulatory noncoding RNAs in medulloblastoma.

Neurooncol Adv 2019 May-Dec;1(1):vdz023. Epub 2019 Sep 6.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/noajnl/vdz023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859950PMC
September 2019

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Nature 2019 10 9;574(7780):707-711. Epub 2019 Oct 9.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41586-019-1650-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141958PMC
October 2019

Characterization of Progressive Cicatrizing Conjunctivitis With Negative Immunofluorescence Staining.

Am J Ophthalmol 2020 01 25;209:3-9. Epub 2019 Sep 25.

Ocular Surface Diseases and Dry Eye Clinic, Division of Cornea and External Diseases, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajo.2019.09.020DOI Listing
January 2020

ADAM3A copy number gains occur in a subset of conjunctival squamous cell carcinoma and its high grade precursors.

Hum Pathol 2019 12 5;94:92-97. Epub 2019 Sep 5.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Sydney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humpath.2019.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917831PMC
December 2019

Downregulation of Nodal inhibits metastatic progression in retinoblastoma.

Acta Neuropathol Commun 2019 08 26;7(1):137. Epub 2019 Aug 26.

Department of Pathology, Johns Hopkins University, School of Medicine, Smith Building, 400 N. Broadway Avenue, Room 4029, Baltimore, MD, 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40478-019-0785-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709548PMC
August 2019

Association of Giant Cell Arteritis With Race.

JAMA Ophthalmol 2019 Aug 8. Epub 2019 Aug 8.

Department of Ophthalmology, Johns Hopkins Wilmer Eye Institute, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamaophthalmol.2019.2919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692689PMC
August 2019

Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma.

Transl Oncol 2019 Oct 21;12(10):1314-1322. Epub 2019 Jul 21.

Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD 21287; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, School of Medicine, Baltimore, MD 21287. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tranon.2019.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657308PMC
October 2019

ATRX Mutations in Pineal Parenchymal Tumors of Intermediate Differentiation.

J Neuropathol Exp Neurol 2019 May 27. Epub 2019 May 27.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnen/nlz050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640895PMC
May 2019

A fox with many faces: FOXR2 and embryonal brain tumors.

Neuro Oncol 2019 May 31. Epub 2019 May 31.

Departments of Pathology and Oncology, Johns Hopkins University.

View Article

Download full-text PDF

Source
https://academic.oup.com/neuro-oncology/article/21/8/963/550
Publisher Site
http://dx.doi.org/10.1093/neuonc/noz102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682211PMC
May 2019

Periocular Histiocytoid Carcinoma: Potential Diagnostic Challenges.

Ocul Oncol Pathol 2019 Feb 5;5(2):94-101. Epub 2018 Jul 5.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
https://www.karger.com/Article/FullText/490250
Publisher Site
http://dx.doi.org/10.1159/000490250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422134PMC
February 2019

Incidence and clinicopathologic features of H3 K27M mutations in adults with radiographically-determined midline gliomas.

J Neurooncol 2019 May 12;143(1):87-93. Epub 2019 Mar 12.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 201 North Broadway, Viragh Building, 9th floor, Post Box 3, Baltimore, MD, 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11060-019-03134-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6482123PMC
May 2019

Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers.

Front Oncol 2019 25;9:96. Epub 2019 Feb 25.

Department of Veterinary Clinical Medicine and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2019.00096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397847PMC
February 2019

Controlled release of dexamethasone sodium phosphate with biodegradable nanoparticles for preventing experimental corneal neovascularization.

Nanomedicine 2019 04 21;17:119-123. Epub 2019 Jan 21.

Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Center for Nanomedicine, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA, USA; Department of Ophthalmology, and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nano.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520116PMC
April 2019

Controlled release of corticosteroid with biodegradable nanoparticles for treating experimental autoimmune uveitis.

J Control Release 2019 02 17;296:68-80. Epub 2019 Jan 17.

Department of Ophthalmology, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Center for Nanomedicine, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 400 North Broadway, Baltimore, MD 21231, USA; Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA; Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, MD 21231, USA; Departments of Oncology, Neurosurgery, and Pharmacology & Molecular Sciences, The Johns Hopkins University, Baltimore, MD 21231, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2019.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476551PMC
February 2019

Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high-MYC medulloblastoma.

Neuropathology 2019 Apr 10;39(2):71-77. Epub 2019 Jan 10.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/neup.12534
Publisher Site
http://dx.doi.org/10.1111/neup.12534DOI Listing
April 2019

Pituitary Adenoma Apoplexy of the Orbit, Diagnosis, and Management With Presurgical Embolization.

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):e196-e197

Johns Hopkins University School of Medicine, Wilmer Eye Institute, Baltimore, Maryland, U.S.A.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IOP.0000000000001241DOI Listing
May 2019

Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33.

Transl Oncol 2019 Jan 3;12(1):96-105. Epub 2018 Oct 3.

Division of Cancer Imaging Research, Department of Radiology and Radiology Science, Johns Hopkins University, School of Medicine, Baltimore, MD; Department of Oncology, Johns Hopkins University, School of Medicine, Baltimore, MD; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19365233183030
Publisher Site
http://dx.doi.org/10.1016/j.tranon.2018.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171097PMC
January 2019

Pathologic study of early manifestations of polypoidal choroidal vasculopathy and pathogenesis of choroidal neo-vascularization.

Am J Ophthalmol Case Rep 2018 Sep 4;11:176-180. Epub 2017 Oct 4.

Wilmer Eye Institute, Johns Hopkins University, School of Medicine, Smith Research Building, Room 4035, 400 North Broadway Street, Baltimore, MD 21287, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajoc.2017.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097175PMC
September 2018

Endocrine mucin-producing sweat gland carcinoma: A study of 11 cases with molecular analysis.

J Cutan Pathol 2018 Jun 25. Epub 2018 Jun 25.

Department of Dermatology, Dermatopathology and Oral Pathology, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cup.13308DOI Listing
June 2018

Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating miRNAs Inhibit Glioblastoma Growth and Prolong Survival.

Nano Lett 2018 07 28;18(7):4086-4094. Epub 2018 Jun 28.

Department of Biomedical Engineering , Institute for NanoBioTechnology, and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine , Baltimore , Maryland 21231 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.nanolett.8b00390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197883PMC
July 2018

Primary mesenchymal chondrosarcoma of the orbit: Histopathological report of 3 pediatric cases.

Saudi J Ophthalmol 2018 Jan-Mar;32(1):69-74. Epub 2018 Mar 8.

Pathology and Laboratory Medicine Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.sjopt.2018.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943970PMC
March 2018

Orbital progressive transformation of germinal centers as part of the spectrum of IgG4-related ophthalmic disease: Clinicopathologic features of three cases.

Saudi J Ophthalmol 2018 Jan-Mar;32(1):56-61. Epub 2018 Mar 10.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.sjopt.2018.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943984PMC
March 2018

Concurrent BRAF/MEK Inhibitors in V600-Mutant High-Grade Primary Brain Tumors.

J Natl Compr Canc Netw 2018 04;16(4):343-347

Department of Neurology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Department of Pathology, Johns Hopkins University; Department of Radiology and Radiological Science, Johns Hopkins Hospital; and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.6004/jnccn.2017.7052DOI Listing
April 2018

Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.

Dev Cell 2018 03 15;44(6):709-724.e6. Epub 2018 Mar 15.

Center for Neuropathology, Ludwig-Maximilians-University, 81377 Munich, Germany; Research Institute Children's Cancer Center Hamburg, Martinistrasse 52, N63 (HPI), Hamburg 20251, Germany; Institute of Neuropathology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany; Department of Pediatric Hematology and Oncology, University Medical Center, Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2018.02.012DOI Listing
March 2018

No BRAF V600E Mutation Identified in 28 Periocular Pyogenic Granuloma.

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):525-527

Department of Pathology, First Affiliated Hospital, Dalian Medical University, Dalian, China.

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00002341-201811000-0000
Publisher Site
http://dx.doi.org/10.1097/IOP.0000000000001075DOI Listing
May 2019

Hemophagocytic Lymphohistiocytosis in Adults with Intraocular Involvement: Clinicopathologic Features of 3 Cases.

Ocul Oncol Pathol 2017 Dec 1;4(1):1-11. Epub 2017 Jun 1.

Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000475551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757609PMC
December 2017

Identifying Corneal Infections in Formalin-Fixed Specimens Using Next Generation Sequencing.

Invest Ophthalmol Vis Sci 2018 01;59(1):280-288

Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.17-21617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770184PMC
January 2018

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Dev Cell 2017 12 2;43(6):673-688.e5. Epub 2017 Nov 2.

Department of Developmental Neurobiology, Neurobiology and Brain Tumor Program, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2017.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736446PMC
December 2017

An immunocompetent mouse model of human glioblastoma.

Oncotarget 2017 Sep 15;8(37):61072-61082. Epub 2017 May 15.

Russel H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.17851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617407PMC
September 2017

Strategies to enhance the distribution of nanotherapeutics in the brain.

J Control Release 2017 Dec 21;267:232-239. Epub 2017 Jul 21.

Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2017.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723233PMC
December 2017

Melanoma subtypes demonstrate distinct PD-L1 expression profiles.

Lab Invest 2017 09 24;97(9):1063-1071. Epub 2017 Jul 24.

Department of Dermatology, Johns Hopkins University School of Medicine, Bloomberg Kimmel Institute for Cancer Immunotherapy, and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/labinvest.2017.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685163PMC
September 2017

Predicting IDH mutation status in grade II gliomas using amide proton transfer-weighted (APTw) MRI.

Magn Reson Med 2017 09 16;78(3):1100-1109. Epub 2017 Jul 16.

Division of MR Research, Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mrm.26820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561497PMC
September 2017

Amide proton transfer-weighted magnetic resonance image-guided stereotactic biopsy in patients with newly diagnosed gliomas.

Eur J Cancer 2017 09 10;83:9-18. Epub 2017 Jul 10.

Department of Radiology, Johns Hopkins University, Baltimore, MD, USA; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2017.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572540PMC
September 2017

Hypoxia inhibits growth, proliferation, and increases response to chemotherapy in retinoblastoma cells.

Exp Eye Res 2017 09 6;162:48-61. Epub 2017 Jul 6.

Departments of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2017.07.001DOI Listing
September 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163053PMC
June 2017

The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity.

Neuro Oncol 2017 Oct;19(10):1361-1371

Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center and Division of Pediatric Oncology and Bloomberg Children's Hospital, Johns Hopkins Hospital, Baltimore, Maryland; St Jude Children's Research Hospital, Memphis, Tennessee.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/neuonc/nox067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604899PMC
October 2017

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma.

Cancer Lett 2017 08 25;400:110-116. Epub 2017 Apr 25.

Department of Pathology, Division of Neuropathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Pediatric Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2017.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569904PMC
August 2017

Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats.

J Control Release 2017 Oct 7;263:112-119. Epub 2017 Mar 7.

Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States; Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, United States; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jconrel.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589496PMC
October 2017

Rabbit Model of Human Gliomas: Implications for Intra-Arterial Drug Delivery.

PLoS One 2017 19;12(1):e0169656. Epub 2017 Jan 19.

Russell H. Morgan Department. of Radiology and Radiological Science, Division of MR Research, Cellular Imaging Section, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169656PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245890PMC
August 2017

Targeting Notch signaling as a novel therapy for retinoblastoma.

Oncotarget 2016 Oct;7(43):70028-70044

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.12142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342532PMC
October 2016

Subepidermal Calcified Nodules of the Eyelid Differ in Children and Adults.

Ophthalmic Plast Reconstr Surg 2017 Jul/Aug;33(4):304-306

*Department of Ophthalmology, King Saud University College of Medicine, Riyadh, Saudi Arabia; †Department of Ophthalmic Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.; ‡Katzen Eye Group, Mercy Medical Center, Baltimore, Maryland, U.S.A.; and §King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IOP.0000000000000778DOI Listing
September 2017

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.65.7825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962737PMC
July 2016

Expression of p16 and p53 in Intraepithelial Periocular Sebaceous Carcinoma.

Ocul Oncol Pathol 2015 Dec 18;2(2):71-5. Epub 2015 Sep 18.

The Johns Hopkins University School of Medicine, Baltimore, Md., USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000439308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847677PMC
December 2015

The transcriptional modulator HMGA2 promotes stemness and tumorigenicity in glioblastoma.

Cancer Lett 2016 07 18;377(1):55-64. Epub 2016 Apr 18.

Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA; Division of Pediatric Oncology, Johns Hopkins University, Bloomberg Children's Hospital, Room 11379, 1800 Orleans St, Baltimore, MD 21287, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2016.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091648PMC
July 2016

Multiple cilia suppress tumour formation.

Authors:
Charles Eberhart

Nat Cell Biol 2016 Apr;18(4):368-9

Johns Hopkins University School of Medicine, Departments of Pathology, Ophthalmology and Oncology, Baltimore, Maryland 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb3331DOI Listing
April 2016

Altered gene expression in conjunctival squamous cell carcinoma.

Mod Pathol 2016 05 26;29(5):452-60. Epub 2016 Feb 26.

Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/modpathol.2016.41DOI Listing
May 2016